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DNA-dependent_RNA_polymerase_subunit_rpo132

Euk-Vir

Murmansk_poxvirus

DNA-dependent_RNA_polymerase_subunit_rpo132__YP_009408322__Murmansk_poxvirus__2025359

Identity

Accession:: YP_009408322 ↗
Protein ID:: DNA-dependent_RNA_polymerase_subunit_rpo132
Kingdom:: euk

Quality

70.8 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Centapoxvirus› Murmansk_poxvirus

TaxID: 2025359

Cluster

View cluster (58 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 38-172

PDB

D2 high residues 491-663

PDB

Domain cluster: rep: RNA_polymerase_RPO132__YP_008004199__Choristoneura_biennis_entomopoxvirus__10288__D504-695

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF04567.23 best	RNA_pol_Rpb2_5	29.2	1.90e-06	27.8%	56.1%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4948672	4961.1.1.1 ↗	a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4	0.76	58.0	6.43e-01	80.9%	95.8%

D3 high residues 738-770_878-1017

PDB

Domain cluster: rep: KU935715.1__AND75470.1__ME3_309__00309__D264-326_420-534

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00562.34 best	RNA_pol_Rpb2_6	86.3	3.30e-24	82.1%	32.7%

D4 medium residues 183-346

PDB

Domain cluster: rep: DNA-directed_RNA_polymerase_subunit_beta__YP_009162498__Salmon_gill_poxvirus__1680908__D173-349

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF12415.15 best	rpo132	64.0	8.20e-18	19.5%	100.0%

D5 medium residues 347-387_413-446

PDB

D6 medium residues 664-737

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00562.34 best	RNA_pol_Rpb2_6	23.8	3.30e-05	87.8%	14.5%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3u0jA00	3.90.176.10	Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1	0.54	45.0	3.28e-01	97.3%	65.1%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3450033	4042.1.1.1 ↗	a+b complex topology › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_6	0.62	55.0	4.57e-01	100.0%	56.7%
3269569	2488.1.1.1 ↗	a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase	0.54	34.0	2.58e-01	100.0%	26.3%
3193611	109.3.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat	0.53	38.0	2.44e-01	79.7%	66.7%

D7 medium residues 773-831_846-875

PDB

Domain cluster: rep: putative_RNA_polymerase_beta_subunit__YP_009052296__Aureococcus_anophagefferens_virus__1474867__D765-873

D8 medium residues 1022-1133

PDB