←Back to structures
DNA-dependent_RNA_polymerase_subunit_rpo147
Euk-VirMurmansk_poxvirus
DNA-dependent_RNA_polymerase_subunit_rpo147__YP_009408276__Murmansk_poxvirus__2025359
Identity
- Accession:
- YP_009408276 ↗
- Protein ID:
- DNA-dependent_RNA_polymerase_subunit_rpo147
- Kingdom:
- euk
Quality
72.6
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Centapoxvirus›
Murmansk_poxvirus
TaxID: 2025359
Cluster
View cluster (32 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 272-311_370-443
Domain cluster:
rep: DNA-dependent_RNA_polymerase_subunit_rpo147__YP_232980__Vaccinia_virus__10245__D277-311_370-443
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00623.26 best | RNA_pol_Rpb1_2 | 48.8 | 1.40e-12 | 64.9% | 41.6% |
D2
high
residues 996-1089
D3
high
residues 1235-1282
D4
medium
residues 34-77_187-255
D5
medium
residues 461-505_565-580
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2jnfA01 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.61 | 44.0 | 4.23e-01 | 80.3% | 98.6% |
| 1xb4B01 | 1.10.10.570 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › """Winged helix"" DNA-binding domain. Chain C. Domain 1" | 0.56 | 38.0 | 3.25e-01 | 70.5% | 100.0% |
| 2p1aB01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.55 | 43.0 | 3.37e-01 | 88.5% | 86.3% |
| 5cqfA00 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.51 | 40.0 | 2.58e-01 | 98.4% | 73.3% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4801460 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 1.00 | 95.0 | 7.20e-01 | 98.4% | 98.3% |
| 4878224 | 108.1.1.18 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_2 | 0.63 | 43.0 | 3.40e-01 | 73.8% | 51.8% |
| 3754560 | 108.1.1.99 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5, EF-hand_6, EF-hand_7 | 0.59 | 40.0 | 3.77e-01 | 72.1% | 77.5% |
| 3918444 | 108.1.1.96 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_6, EF-hand_7 | 0.57 | 39.0 | 2.88e-01 | 73.8% | 42.2% |
| 3399181 | 108.1.1.99 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5, EF-hand_6, EF-hand_7 | 0.56 | 42.0 | 3.51e-01 | 82.0% | 82.7% |
| 3922770 | 108.1.1.97 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_7 | 0.55 | 39.0 | 3.37e-01 | 77.0% | 84.8% |
| 5040994 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.54 | 32.0 | 3.08e-01 | 91.8% | 48.0% |
| 3642524 | 108.1.1.96 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_6, EF-hand_7 | 0.53 | 41.0 | 3.32e-01 | 85.2% | 71.2% |
| 3959289 | 2003.1.2.69 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › NAD_binding_8, Pyr_redox_3 | 0.52 | 43.0 | 3.18e-01 | 100.0% | 59.5% |
D6
medium
residues 506-564
Domain cluster:
representative
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4c3iA04 | 1.10.274.100 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 | 0.85 | 78.0 | 5.55e-01 | 100.0% | 51.6% |
| 6f40A01 | 1.10.274.100 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 | 0.84 | 75.0 | 5.54e-01 | 100.0% | 59.3% |
| 1twfA05 | 1.10.274.100 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 | 0.81 | 72.0 | 5.31e-01 | 100.0% | 47.7% |
| 7oqyA01 | 1.10.274.100 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 | 0.78 | 69.0 | 5.12e-01 | 100.0% | 54.4% |
| 1bqbA02 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.60 | 53.0 | 4.02e-01 | 100.0% | 41.7% |
| 8fnyA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 40.0 | 2.84e-01 | 86.4% | 30.6% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4801460 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.97 | 92.0 | 6.98e-01 | 100.0% | 48.8% |
| 3923417 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.88 | 80.0 | 5.69e-01 | 100.0% | 49.7% |
| 4012261 | 4959.1.1.0 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit | 0.88 | 80.0 | 5.72e-01 | 100.0% | 55.0% |
| 3693563 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.86 | 78.0 | 5.61e-01 | 100.0% | 54.4% |
| 4979447 | 4959.1.1.0 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit | 0.86 | 77.0 | 5.48e-01 | 100.0% | 47.9% |
| 3670781 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.86 | 77.0 | 5.46e-01 | 100.0% | 58.8% |
| 3722538 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.85 | 77.0 | 5.34e-01 | 100.0% | 56.1% |
| 3709289 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.85 | 76.0 | 5.51e-01 | 100.0% | 54.2% |
| 4948679 | 1.1.2.2 ↗ | beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 | 0.84 | 76.0 | 4.66e-01 | 100.0% | 18.4% |
| 4933545 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.84 | 76.0 | 5.73e-01 | 100.0% | 51.1% |
| 5000429 | 4959.1.1.0 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit | 0.84 | 76.0 | 5.60e-01 | 100.0% | 51.0% |
| 4015758 | 4959.1.1.0 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit | 0.84 | 76.0 | 5.44e-01 | 100.0% | 51.9% |
| 3414196 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.84 | 75.0 | 5.34e-01 | 100.0% | 57.6% |
| 5048449 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.84 | 75.0 | 5.42e-01 | 100.0% | 50.6% |
| 3483005 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.84 | 75.0 | 5.30e-01 | 100.0% | 52.0% |
| 4966694 | 4959.1.1.0 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit | 0.83 | 75.0 | 5.67e-01 | 100.0% | 59.3% |
| 4943461 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.83 | 74.0 | 5.44e-01 | 100.0% | 54.0% |
| 3235040 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.82 | 73.0 | 5.35e-01 | 100.0% | 52.9% |
| 3614240 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.82 | 73.0 | 5.48e-01 | 100.0% | 51.4% |
| 4261866 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.82 | 73.0 | 5.27e-01 | 100.0% | 53.1% |
| 4667658 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.81 | 72.0 | 5.16e-01 | 100.0% | 45.5% |
| 4983204 | 4959.1.1.0 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit | 0.80 | 71.0 | 5.37e-01 | 100.0% | 60.7% |
| 2772083 | 4959.1.1.1 ↗ | a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 | 0.78 | 68.0 | 5.07e-01 | 100.0% | 54.0% |
D7
medium
residues 581-652
Domain cluster:
rep: RNA_polymerase__YP_010085368__Eastern_grey_kangaroopox_virus__2042482__D580-658
D8
medium
residues 653-748
Domain cluster:
rep: putative_DNA_directed_RNA_polymerase_largest_subunit__YP_009052394__Aureococcus_anophagefferens_virus__1474867__D688-749
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05000.23 best | RNA_pol_Rpb1_4 | 53.9 | 2.10e-14 | 68.8% | 57.0% |
D9
medium
residues 790-912
D10
medium
residues 913-972