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DNA-directed_RNA_polymerase_subunit_1

Euk-Vir

Acanthamoeba_polyphaga_mimivirus

DNA-directed_RNA_polymerase_subunit_1__YP_003987013__Acanthamoeba_polyphaga_mimivirus__212035

Identity

Accession:
YP_003987013 ↗
Protein ID:
DNA-directed_RNA_polymerase_subunit_1
Kingdom:
euk

Quality

72.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 103-226
PDB
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3hi2B00 3.30.2310.40 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › 0.66 27.0 3.08e-01 85.5% 47.4%
4dm5A00 3.30.1450.10 Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › 0.57 27.0 3.14e-01 88.7% 60.9%
1pcfA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.54 28.0 3.59e-01 95.2% 90.9%
2nwvA00 3.30.310.110 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › XisI-like 0.52 33.0 3.45e-01 92.7% 70.5%
2f20A00 3.90.1680.10 Alpha Beta › Alpha-Beta Complex › hypothetical protein yedk fold › SOS response associated peptidase-like 0.52 42.0 3.47e-01 89.5% 95.7%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4803223 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.90 71.0 5.19e-01 100.0% 34.2%
4648965 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.89 78.0 5.51e-01 100.0% 34.2%
4871979 4246.1.1.4 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 0.87 72.0 5.91e-01 100.0% 51.0%
3596097 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.84 73.0 5.22e-01 100.0% 35.3%
4023558 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.83 79.0 5.50e-01 100.0% 40.0%
3610049 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.82 78.0 5.45e-01 100.0% 39.4%
4027469 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.81 77.0 5.45e-01 100.0% 37.3%
3487002 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.81 78.0 5.43e-01 100.0% 38.3%
4838956 4246.1.1.4 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 0.77 67.0 5.67e-01 100.0% 57.9%
3479543 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.77 73.0 5.11e-01 100.0% 39.7%
3393665 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.77 73.0 5.10e-01 100.0% 40.9%
4079870 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.76 73.0 5.06e-01 100.0% 36.9%
3348138 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.76 72.0 5.06e-01 100.0% 39.4%
3596876 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.76 72.0 5.08e-01 100.0% 42.9%
4809191 4246.1.1.4 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 0.74 67.0 5.31e-01 94.4% 59.0%
5056462 4312.1.1.0 a+b two layers › RelE-like › RelE-like › RelE-like 0.58 26.0 3.01e-01 84.7% 54.4%
5019065 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.51 35.0 2.44e-01 91.9% 18.7%
D2 high residues 542-662
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04983.24 best RNA_pol_Rpb1_3 62.4 7.00e-17 100.0% 84.6%
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1twfA05 1.10.274.100 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 0.93 90.0 8.17e-01 100.0% 88.9%
7oqyA01 1.10.274.100 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 0.90 86.0 7.95e-01 100.0% 96.0%
4qiwA04 1.10.274.100 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 0.90 86.0 7.33e-01 100.0% 81.4%
6f40A01 1.10.274.100 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 0.88 81.0 7.46e-01 96.7% 100.0%
4c3iA04 1.10.274.100 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 0.88 84.0 7.48e-01 100.0% 95.7%
7eu1A02 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.82 78.0 7.54e-01 100.0% 95.5%
6j9eD01 1.10.274.100 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 0.64 61.0 6.00e-01 99.2% 100.0%
2go7A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.64 36.0 4.60e-01 96.7% 98.5%
5tw1D01 1.10.274.100 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › RNA polymerase Rpb1, domain 3 0.62 59.0 5.50e-01 99.2% 100.0%
3vskA03 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.56 45.0 3.20e-01 86.0% 100.0%
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.54 39.0 3.73e-01 91.7% 64.5%
2km6A00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.52 38.0 4.19e-01 88.4% 96.9%
2jokA01 1.10.4120.10 Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › SopE-like, GEF domain 0.52 44.0 3.96e-01 95.0% 68.6%
4f92B10 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.51 40.0 3.85e-01 85.1% 88.1%
ECOD (61)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3235040 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.93 90.0 8.09e-01 100.0% 93.5%
4936467 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.93 90.0 7.98e-01 100.0% 95.6%
3486998 4959.1.1.0 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit 0.93 89.0 8.18e-01 100.0% 96.7%
4979447 4959.1.1.0 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit 0.93 89.0 7.77e-01 100.0% 84.6%
5048449 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.92 89.0 7.91e-01 100.0% 89.4%
4667658 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.92 89.0 7.80e-01 100.0% 97.6%
5040549 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.92 88.0 7.76e-01 100.0% 89.7%
5034276 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.91 88.0 7.84e-01 100.0% 88.7%
5058904 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.91 85.0 7.66e-01 97.5% 88.6%
3923417 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.91 87.0 7.68e-01 100.0% 95.8%
4261866 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.91 87.0 7.74e-01 100.0% 96.2%
1641048 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.91 87.0 7.82e-01 100.0% 95.5%
3614240 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.91 87.0 8.22e-01 100.0% 95.0%
5043376 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.90 87.0 8.08e-01 100.0% 93.8%
2772083 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.90 86.0 7.92e-01 100.0% 95.3%
4994701 4959.1.1.0 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit 0.90 87.0 7.96e-01 100.0% 96.0%
4938234 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.90 87.0 8.20e-01 100.0% 87.9%
4933545 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.90 87.0 8.33e-01 100.0% 97.0%
4932734 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.90 82.0 8.16e-01 100.0% 92.0%
3596096 4959.1.1.0 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit 0.90 87.0 8.17e-01 100.0% 95.0%
5054582 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.90 87.0 8.17e-01 100.0% 94.3%
3693563 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.90 86.0 7.68e-01 100.0% 95.0%
4012261 4959.1.1.0 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit 0.90 86.0 7.67e-01 100.0% 95.6%
3670781 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.90 86.0 7.48e-01 100.0% 97.1%
3592133 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.89 86.0 7.17e-01 100.0% 96.3%
5028611 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.89 86.0 7.75e-01 100.0% 93.5%
3709289 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.89 85.0 7.73e-01 100.0% 96.1%
5000429 4959.1.1.0 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit 0.89 86.0 7.97e-01 100.0% 93.8%
3414196 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.89 86.0 7.45e-01 100.0% 96.5%
4948679 1.1.2.2 beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb1_2 0.89 86.0 6.01e-01 100.0% 37.4%
3722538 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.89 85.0 7.24e-01 100.0% 95.6%
3483005 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.89 85.0 7.31e-01 100.0% 95.4%
4942642 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.88 85.0 8.28e-01 100.0% 93.8%
3821067 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.88 84.0 6.98e-01 100.0% 96.9%
4015758 4959.1.1.0 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit 0.87 83.0 7.40e-01 99.2% 95.6%
3206396 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.85 74.0 7.60e-01 100.0% 93.9%
3834810 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.84 80.0 7.65e-01 100.0% 94.8%
4801460 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.83 74.0 7.46e-01 100.0% 94.2%
3355872 4959.1.1.0 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit 0.82 78.0 7.59e-01 100.0% 94.6%
3835221 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.81 77.0 7.54e-01 100.0% 94.6%
3942099 605.1.1.209 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › AI-2E_transport 0.66 44.0 4.83e-01 90.9% 82.0%
4302020 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.66 63.0 5.76e-01 100.0% 92.0%
4667069 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.66 62.0 5.39e-01 100.0% 94.3%
4057414 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.64 62.0 5.52e-01 100.0% 93.8%
4289952 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.64 61.0 5.39e-01 100.0% 98.2%
4362500 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.64 61.0 5.71e-01 100.0% 95.2%
4235207 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.64 61.0 5.26e-01 100.0% 93.1%
4438819 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.64 60.0 5.36e-01 100.0% 95.8%
4445936 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.64 61.0 5.59e-01 100.0% 96.0%
4280869 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.64 61.0 5.84e-01 100.0% 97.0%
4394123 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.63 60.0 5.62e-01 100.0% 95.9%
4172986 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.63 60.0 5.79e-01 100.0% 98.5%
4639456 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.62 59.0 5.46e-01 100.0% 93.3%
4440636 4959.1.1.1 a+b complex topology › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › first helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_3 0.62 59.0 5.59e-01 100.0% 94.3%
3549279 5054.1.1.2 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.61 44.0 2.50e-01 75.2% 37.8%
4997589 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.56 39.0 3.79e-01 90.1% 63.7%
3743981 5081.1.1.2 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › DER1 0.54 45.0 3.83e-01 91.7% 56.3%
5022243 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.53 36.0 3.44e-01 91.7% 57.9%
5076317 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.52 35.0 3.42e-01 86.8% 63.1%
4970826 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.51 36.0 3.40e-01 90.1% 59.3%
3601731 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 36.0 2.12e-01 74.4% 15.3%
D3 medium residues 30-97_240-265
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04997.18 best RNA_pol_Rpb1_1 62.9 4.80e-17 75.5% 18.6%
D4 medium residues 266-347
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04997.18 best RNA_pol_Rpb1_1 83.1 3.40e-23 100.0% 25.6%
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3rklA00 6.10.140.1640 Special › Helix non-globular › Helix Hairpins › 0.85 56.0 5.73e-01 97.6% 68.8%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.83 57.0 5.22e-01 100.0% 56.9%
1grjA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.81 57.0 6.06e-01 98.8% 81.1%
3sjqC00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.80 58.0 5.88e-01 100.0% 76.2%
3l1nA01 6.10.140.790 Special › Helix non-globular › Helix Hairpins › 0.75 45.0 5.60e-01 81.7% 98.0%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 48.0 4.78e-01 96.3% 62.8%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.74 59.0 5.39e-01 100.0% 66.0%
2xokP00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.72 49.0 5.13e-01 97.6% 78.4%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.71 52.0 4.91e-01 93.9% 64.6%
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.71 47.0 5.18e-01 98.8% 85.9%
4nsmA00 6.10.250.2770 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.70 48.0 5.13e-01 95.1% 81.7%
2qkdA04 2.60.120.1040 Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain 0.69 44.0 3.78e-01 75.6% 42.5%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.68 46.0 5.07e-01 97.6% 86.6%
2bskB00 1.10.287.810 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains 0.67 40.0 4.47e-01 93.9% 75.4%
4rm7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 50.0 4.16e-01 78.0% 93.5%
2a3qA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.67 46.0 4.12e-01 90.2% 51.3%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 49.0 3.66e-01 100.0% 31.0%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.66 46.0 4.93e-01 97.6% 86.8%
3ecqA07 6.10.140.660 Special › Helix non-globular › Helix Hairpins › 0.66 34.0 4.26e-01 75.6% 88.9%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 45.0 4.00e-01 100.0% 50.4%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.62 45.0 4.66e-01 100.0% 80.8%
3nb0B03 6.10.260.10 Special › Helix non-globular › F1FO ATP Synthase › 0.61 45.0 4.50e-01 100.0% 76.2%
2j3tD01 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.60 37.0 3.21e-01 92.7% 38.8%
3hgtA00 3.40.50.12360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 49.0 3.50e-01 97.6% 83.2%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.59 43.0 3.63e-01 93.9% 46.7%
2jx4A01 6.10.140.460 Special › Helix non-globular › Helix Hairpins › 0.58 35.0 4.15e-01 92.7% 100.0%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.57 47.0 4.58e-01 100.0% 83.1%
3fd0A01 3.90.1150.60 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Methioning gamme-lyase, C-terminal domain 0.56 46.0 3.52e-01 90.2% 85.0%
2hgkA01 1.20.1440.40 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › YqcC-like 0.54 39.0 3.65e-01 76.8% 100.0%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.54 44.0 4.05e-01 98.8% 67.9%
3r0qA02 2.70.160.11 Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 0.52 45.0 3.42e-01 100.0% 87.5%
3q23A08 1.20.140.110 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.51 44.0 3.61e-01 97.6% 98.7%
ECOD (45)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3487002 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.89 83.0 5.26e-01 100.0% 23.2%
5026630 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.89 83.0 5.32e-01 100.0% 24.6%
4023558 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.89 78.0 4.97e-01 95.1% 22.0%
4648965 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.89 82.0 5.26e-01 100.0% 24.2%
4228406 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.89 82.0 5.37e-01 100.0% 27.7%
4380798 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.89 82.0 5.27e-01 100.0% 24.6%
3951780 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.88 81.0 4.95e-01 100.0% 18.8%
3596097 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.88 81.0 5.21e-01 100.0% 24.7%
4090024 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.88 81.0 5.16e-01 100.0% 23.6%
3610049 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.88 81.0 5.12e-01 100.0% 22.9%
4803223 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.88 74.0 4.85e-01 90.2% 24.4%
4513601 4246.1.1.0 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.88 81.0 4.75e-01 100.0% 14.9%
4367766 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.88 81.0 5.00e-01 100.0% 19.8%
4410658 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.87 81.0 4.96e-01 100.0% 19.3%
4036245 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.87 78.0 4.81e-01 98.8% 19.2%
4344997 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.87 82.0 5.19e-01 100.0% 23.4%
4815139 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 76.0 6.62e-01 96.3% 66.1%
4647819 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.86 81.0 5.05e-01 100.0% 22.1%
4261674 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.85 80.0 5.20e-01 100.0% 26.2%
4469646 4246.1.1.2 a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 0.82 77.0 4.94e-01 100.0% 24.9%
3507431 11.2.1.7 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › Anillin 0.79 56.0 3.99e-01 100.0% 27.1%
3447097 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.78 54.0 4.81e-01 100.0% 52.7%
3331217 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 56.0 4.18e-01 100.0% 32.1%
3847053 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.77 48.0 5.05e-01 100.0% 69.3%
3730904 650.1.1.14 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › Med10 0.72 53.0 5.10e-01 96.3% 68.9%
3178092 611.3.1.0 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.70 40.0 3.78e-01 95.1% 46.0%
3441169 159.1.1.2 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG-like 0.70 51.0 4.35e-01 85.4% 49.6%
3554599 159.1.2.4 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › MazG-like 0.70 51.0 4.36e-01 85.4% 49.6%
3493322 2006.1.1.8 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › 5_nucleotid 0.69 46.0 3.16e-01 87.8% 21.7%
4440629 192.3.1.1 alpha bundles › Long alpha-hairpin › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Fe,Mn superoxide dismutase (SOD), N-terminal domain › Sod_Fe_N 0.68 48.0 4.67e-01 100.0% 66.7%
3711237 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.64 45.0 4.58e-01 72.0% 75.0%
4486891 5059.1.1.5 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA 0.64 51.0 3.28e-01 84.1% 80.9%
1770995 223.2.1.8 a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.62 37.0 2.77e-01 79.3% 24.3%
4977511 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.62 48.0 4.27e-01 93.9% 58.3%
3299464 159.1.2.4 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › MazG-like 0.62 41.0 3.74e-01 90.2% 50.0%
4361357 5046.1.1.1 extended segments › F-type ATP synthase subunit b › F-type ATP synthase subunit b › F-type ATP synthase subunit b › ATP-synt_B 0.62 44.0 3.49e-01 98.8% 35.9%
3795092 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.61 58.0 4.80e-01 100.0% 60.7%
3979725 3291.1.1.15 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF2583 0.61 46.0 4.53e-01 100.0% 74.4%
4818504 325.1.7.2 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.56 40.0 3.25e-01 74.4% 49.3%
4822508 3681.1.1.0 a+b complex topology › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit 0.56 39.0 3.94e-01 74.4% 81.9%
4220179 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.55 42.0 3.91e-01 86.6% 63.8%
4150217 633.2.1.1 alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein › EntA_Immun 0.55 46.0 4.53e-01 91.5% 100.0%
4512991 4954.1.1.1 a+b complex topology › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › central helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5 0.55 46.0 3.42e-01 100.0% 73.1%
3716068 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 39.0 2.62e-01 95.1% 19.4%
5046582 3921.1.1.3 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › GDT1 0.52 44.0 3.38e-01 92.7% 62.2%
D5 medium residues 667-751
PDB
Domain cluster: representative
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h0gA05 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.93 88.0 7.11e-01 100.0% 61.6%
4aybA07 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.90 82.0 7.20e-01 97.6% 73.3%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.81 60.0 5.59e-01 76.5% 67.6%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.80 56.0 6.28e-01 75.3% 95.4%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 53.0 4.92e-01 71.8% 57.4%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.77 57.0 5.80e-01 78.8% 78.8%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 55.0 4.84e-01 76.5% 53.3%
2kseA00 1.20.5.1040 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Sensor protein qsec. 0.72 50.0 5.25e-01 71.8% 83.1%
3fxdB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 45.0 5.41e-01 89.4% 94.8%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.70 61.0 4.26e-01 95.3% 83.2%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 48.0 4.66e-01 75.3% 65.6%
1qgtB00 1.10.4090.10 Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus 0.67 57.0 4.79e-01 92.9% 71.3%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.67 49.0 4.99e-01 77.6% 87.8%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.67 46.0 3.62e-01 71.8% 83.0%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 50.0 3.57e-01 78.8% 29.2%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 48.0 3.97e-01 77.6% 82.1%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.65 49.0 4.24e-01 81.2% 69.2%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.65 46.0 3.89e-01 92.9% 43.8%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 41.0 4.86e-01 72.9% 94.9%
4adzA00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.64 54.0 5.31e-01 91.8% 88.9%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.64 45.0 4.50e-01 74.1% 86.7%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 44.0 5.05e-01 80.0% 100.0%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 47.0 3.84e-01 78.8% 82.6%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.63 44.0 3.89e-01 71.8% 52.5%
3hpcX00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.62 49.0 4.11e-01 87.1% 70.3%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.62 43.0 4.36e-01 71.8% 80.0%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.62 49.0 4.17e-01 97.6% 51.0%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 47.0 4.59e-01 82.4% 75.0%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 44.0 4.72e-01 78.8% 88.0%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.60 50.0 4.25e-01 92.9% 71.0%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.60 44.0 4.23e-01 76.5% 86.5%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.60 51.0 5.11e-01 92.9% 94.1%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 43.0 4.11e-01 75.3% 67.0%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.59 44.0 4.85e-01 85.9% 100.0%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 46.0 4.01e-01 83.5% 55.5%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.59 53.0 4.16e-01 100.0% 48.9%
2e9xB02 1.20.58.1020 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 37.0 3.41e-01 70.6% 50.5%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.58 41.0 4.59e-01 74.1% 97.0%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 49.0 3.78e-01 94.1% 64.6%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 41.0 3.95e-01 78.8% 68.4%
1jkvA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 44.0 3.42e-01 90.6% 77.7%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.53 47.0 3.82e-01 96.5% 69.2%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3711496 4958.1.1.1 a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_5,RNA_pol_Rpb1_4 0.95 91.0 6.47e-01 100.0% 41.9%
3717860 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.85 62.0 6.14e-01 76.5% 74.4%
5055960 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.78 55.0 4.85e-01 76.5% 51.7%
3953372 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.76 57.0 5.45e-01 78.8% 71.4%
5064072 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.76 58.0 5.70e-01 90.6% 75.6%
3591396 3866.1.1.0 extended segments › Mitochondrial 54S ribosomal protein L25 › Mitochondrial 54S ribosomal protein L25 › Mitochondrial 54S ribosomal protein L25 0.76 52.0 5.07e-01 77.6% 64.2%
3701375 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 51.0 4.98e-01 76.5% 63.2%
5017847 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.74 67.0 6.34e-01 100.0% 88.0%
None 0.73 57.0 3.95e-01 82.4% 28.5%
4033272 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.73 56.0 4.97e-01 81.2% 60.8%
4989238 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.72 56.0 5.08e-01 83.5% 75.7%
5044927 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.71 49.0 5.69e-01 81.2% 100.0%
4939465 622.1.1.0 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.70 48.0 4.40e-01 71.8% 53.0%
5050114 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.70 54.0 5.28e-01 85.9% 76.7%
3410128 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.70 51.0 5.64e-01 76.5% 100.0%
3935140 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.70 50.0 3.83e-01 74.1% 38.3%
4982694 3843.1.1.35 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF1634 0.69 57.0 5.46e-01 94.1% 79.6%
3291561 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 47.0 4.95e-01 70.6% 82.7%
4950709 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.68 48.0 5.42e-01 76.5% 96.9%
4575830 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 55.0 3.45e-01 88.2% 58.4%
3635408 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 51.0 4.37e-01 83.5% 52.1%
3741935 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.66 55.0 4.30e-01 91.8% 89.2%
4964878 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.66 47.0 5.18e-01 81.2% 91.4%
4505128 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.65 44.0 4.40e-01 75.3% 66.7%
4674 192.7.1.1 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › FemAB 0.64 46.0 5.16e-01 76.5% 96.9%
4329615 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.64 45.0 4.87e-01 80.0% 88.6%
5006970 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.64 46.0 3.95e-01 76.5% 72.9%
3278037 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.64 47.0 3.54e-01 82.4% 33.3%
3948872 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 48.0 4.13e-01 78.8% 93.8%
4238998 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.63 44.0 4.68e-01 74.1% 91.4%
3968516 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.62 47.0 4.98e-01 80.0% 93.3%
3788511 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.62 49.0 3.02e-01 82.4% 32.7%
4006721 325.1.7.50 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25876 0.61 48.0 4.87e-01 83.5% 88.2%
3948731 192.10.1.1 alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain › DksA_N 0.61 51.0 4.56e-01 90.6% 74.2%
3732192 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.61 46.0 4.83e-01 83.5% 92.0%
4362754 5086.1.1.86 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG 0.60 48.0 4.28e-01 85.9% 60.0%
4951992 5041.1.1.55 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › DUF1622 0.60 49.0 4.69e-01 92.9% 78.0%
3410365 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.60 53.0 3.47e-01 100.0% 24.2%
3386973 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.59 46.0 4.58e-01 83.5% 84.4%
3775580 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.59 44.0 4.62e-01 82.4% 89.3%
3281879 101.1.2.48 alpha arrays › HTH › HTH › winged helix domain › PadR 0.59 42.0 3.33e-01 82.4% 35.6%
5040143 208.1.1.6 beta duplicates or obligate multimers › Single-stranded left-handed beta-helix › Trimeric LpxA-like enzymes › Trimeric LpxA-like enzymes › Hexapep_2 0.59 50.0 3.80e-01 98.8% 70.7%
2067201 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.57 45.0 4.67e-01 83.5% 100.0%
4317199 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.56 43.0 3.78e-01 84.7% 56.0%
3832264 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.55 46.0 2.92e-01 95.3% 36.9%
4945692 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.51 35.0 3.45e-01 80.0% 64.2%
3440543 207.1.1.96 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_At1g61320_AtMIF1 0.51 46.0 2.87e-01 100.0% 23.8%
D6 medium residues 752-843
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF05000.23 best RNA_pol_Rpb1_4 41.9 1.10e-10 50.0% 41.1%
PF04998.23 RNA_pol_Rpb1_5 60.9 1.90e-16 43.5% 15.0%
D7 medium residues 880-954
PDB
D8 medium residues 955-999_1015-1056
PDB
D9 medium residues 1188-1285
PDB