←Back to structures

DNA-directed_RNA_polymerase_subunit_RPB2

Euk-Vir

Pithovirus_sibericum

DNA-directed_RNA_polymerase_subunit_RPB2__YP_009001144__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001144 ↗
Protein ID:
DNA-directed_RNA_polymerase_subunit_RPB2
Kingdom:
euk

Quality

79.4 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

View cluster (58 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 887-980
PDB
Domain cluster: rep: hypothetical_protein_MIV009R__YP_654581__Invertebrate_iridescent_virus_3__345201__D796-874
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00562.34 best RNA_pol_Rpb2_6 27.9 1.90e-06 100.0% 25.2%
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1twfB07 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.86 81.0 7.23e-01 100.0% 75.0%
2pmzB07 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.85 79.0 7.12e-01 100.0% 75.0%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.83 78.0 6.22e-01 100.0% 92.0%
2a6hC06 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.82 77.0 6.70e-01 100.0% 87.2%
6ruiB07 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.74 68.0 6.10e-01 100.0% 76.2%
1x0tA02 6.20.50.20 Special › Other non-globular › N-terminal domain of TfIIb › 0.60 26.0 3.51e-01 70.2% 75.6%
1x3zA04 2.20.25.10 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.58 33.0 4.21e-01 72.3% 100.0%
4mbrA02 2.60.40.1290 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 40.0 3.42e-01 84.0% 84.9%
1g29102 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 25.0 3.36e-01 89.4% 91.1%
4fwwA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 39.0 2.55e-01 79.8% 32.3%
1iz6A01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.52 31.0 3.49e-01 76.6% 79.7%
1a15A00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.52 28.0 3.27e-01 90.4% 74.6%
3tdgA01 3.10.450.520 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 28.0 3.23e-01 86.2% 74.2%
2eqmA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.51 27.0 3.33e-01 93.6% 88.7%
1qypA00 2.20.25.10 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.51 26.0 3.11e-01 84.0% 75.4%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3556801 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.90 86.0 7.64e-01 100.0% 84.8%
4946076 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.89 85.0 7.60e-01 100.0% 86.4%
4970832 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.89 85.0 7.55e-01 100.0% 84.8%
4956728 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.89 85.0 7.44e-01 100.0% 85.4%
4682340 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.89 84.0 7.51e-01 100.0% 85.6%
4976162 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.88 84.0 7.60e-01 100.0% 88.3%
5000301 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.88 83.0 7.66e-01 100.0% 88.7%
4629505 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.87 82.0 7.04e-01 100.0% 91.4%
4932693 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.87 82.0 7.49e-01 100.0% 87.5%
5070341 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.87 82.0 7.37e-01 100.0% 87.2%
4297838 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.85 79.0 7.61e-01 100.0% 87.6%
4026621 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.85 81.0 7.46e-01 100.0% 84.3%
4513514 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.85 81.0 7.21e-01 100.0% 92.0%
4135657 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.85 79.0 6.93e-01 100.0% 91.9%
3491434 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.85 80.0 7.05e-01 100.0% 89.2%
4323756 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.84 79.0 6.90e-01 100.0% 89.6%
3056924 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.84 79.0 5.66e-01 100.0% 93.9%
3728982 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.84 79.0 7.00e-01 100.0% 83.8%
4255464 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.84 79.0 5.65e-01 100.0% 93.1%
3302882 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.84 78.0 7.04e-01 100.0% 84.0%
3792089 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.84 79.0 6.86e-01 100.0% 85.2%
3786933 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.84 79.0 7.05e-01 100.0% 86.4%
4876258 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.83 78.0 6.77e-01 100.0% 84.1%
4120984 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.83 79.0 7.29e-01 100.0% 84.3%
4886404 4042.1.1.1 ↗ a+b complex topology › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › barrel domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_6 0.83 79.0 5.79e-01 100.0% 94.5%
4599969 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.83 78.0 7.52e-01 100.0% 90.5%
4921634 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.83 78.0 7.30e-01 100.0% 84.8%
4654615 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.83 78.0 5.66e-01 100.0% 92.6%
4366177 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.82 77.0 5.63e-01 100.0% 92.6%
4638008 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.82 77.0 7.02e-01 100.0% 85.0%
4069281 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.82 77.0 6.29e-01 100.0% 88.7%
4175999 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.81 76.0 7.19e-01 100.0% 90.0%
2714993 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.80 76.0 6.39e-01 100.0% 72.1%
4587173 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.79 74.0 7.12e-01 100.0% 88.6%
4067177 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.78 74.0 6.94e-01 100.0% 88.2%
3801974 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.77 69.0 6.50e-01 100.0% 81.8%
3616946 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.76 66.0 6.41e-01 100.0% 84.8%
3517994 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.75 67.0 6.50e-01 100.0% 86.7%
3695559 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.74 67.0 5.99e-01 100.0% 84.6%
4026378 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 30.0 2.22e-01 73.4% 16.1%
4932876 375.1.1.26 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 0.61 31.0 2.89e-01 80.9% 39.1%
3490945 3256.1.1.0 ↗ a+b two layers › DUF2233 N-terminal domain › DUF2233 N-terminal domain › DUF2233 N-terminal domain 0.61 32.0 3.78e-01 78.7% 76.7%
5029226 375.1.1.21 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-ZPR1 0.60 35.0 4.40e-01 76.6% 100.0%
4172303 375.1.1.26 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 0.58 34.0 3.13e-01 80.9% 44.8%
3253618 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 39.0 4.18e-01 84.0% 93.8%
3473251 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 41.0 3.58e-01 86.2% 92.0%
5030911 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.53 39.0 4.21e-01 80.9% 89.2%
136515 1170.1.1.1 ↗ beta barrels › IL8-related › IL8-related › IL8 › IL8 0.52 28.0 3.25e-01 90.4% 72.1%
3392728 331.9.1.8 ↗ a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain › AP3B1_C_2 0.51 36.0 3.28e-01 73.4% 71.2%
D2 medium residues 87-115_133-162
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2v3aA03 3.30.390.120 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.61 35.0 3.50e-01 93.2% 51.6%
3iq2A00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.57 41.0 3.29e-01 93.2% 36.6%
2k75A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 35.0 2.98e-01 88.1% 35.9%
4damC00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 39.0 3.32e-01 86.4% 44.0%
2gdqA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.54 40.0 3.40e-01 93.2% 45.8%
2kieA00 2.30.29.110 Mainly Beta › Roll › PH-domain like › 0.53 33.0 2.70e-01 88.1% 29.8%
2y6uA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 41.0 2.60e-01 88.1% 89.2%
2chrA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.52 36.0 2.95e-01 76.3% 96.1%
3vfcA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.52 38.0 2.95e-01 81.4% 85.2%
2oztA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.51 38.0 3.14e-01 83.1% 94.1%
2pgwA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.51 37.0 2.90e-01 81.4% 87.3%
4p2iA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.51 37.0 3.03e-01 93.2% 40.2%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5013672 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.56 39.0 3.81e-01 89.8% 66.2%
5014602 504.1.1.0 ↗ a+b two layers › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB 0.55 42.0 3.38e-01 94.9% 39.2%
5037301 2.1.1.111 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ssb-like_OB 0.55 36.0 3.10e-01 88.1% 40.4%
5043294 504.1.1.0 ↗ a+b two layers › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB 0.55 41.0 3.29e-01 93.2% 38.5%
4964647 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.54 36.0 3.18e-01 88.1% 45.6%
3256415 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 43.0 3.75e-01 94.9% 78.9%
D3 medium residues 116-132_163-208_392-482
PDB
Domain cluster: rep: conserved_DNA-directed_RNA_polymerase_subunit_beta__YP_009094523__Melbournevirus__1560514__D73-184_383-448
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04563.21 best RNA_pol_Rpb2_1 56.8 3.30e-15 71.4% 41.9%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k17A02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.55 25.0 2.64e-01 79.9% 45.7%
3hx3A01 1.10.8.20 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › N-terminal domain of phosphatidylinositol transfer protein sec14p 0.50 23.0 3.20e-01 86.4% 94.0%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3492370 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.90 87.0 6.74e-01 100.0% 60.3%
3824946 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.89 86.0 6.49e-01 100.0% 56.9%
3450034 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.89 86.0 6.58e-01 100.0% 57.4%
4021691 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.89 86.0 6.21e-01 100.0% 59.0%
3639746 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.88 85.0 6.22e-01 100.0% 51.4%
4292527 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.88 85.0 6.46e-01 100.0% 56.5%
4029039 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.88 84.0 6.03e-01 100.0% 54.6%
3601611 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.88 85.0 6.38e-01 100.0% 52.6%
3509883 4010.1.1.1 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.87 85.0 6.49e-01 100.0% 56.7%
3605313 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.87 84.0 5.73e-01 100.0% 52.4%
4956724 4010.1.1.1 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.86 83.0 6.45e-01 100.0% 55.6%
3596939 4010.1.1.0 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.86 82.0 5.54e-01 100.0% 49.9%
3515716 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.85 83.0 6.47e-01 100.0% 56.2%
5026625 4010.1.1.0 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.85 83.0 6.30e-01 100.0% 55.8%
4946072 4010.1.1.1 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.85 83.0 6.36e-01 100.0% 56.3%
4513137 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.84 81.0 6.06e-01 100.0% 54.0%
5009207 4010.1.1.1 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.84 81.0 6.03e-01 100.0% 53.2%
5059473 4010.1.1.0 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.84 81.0 6.15e-01 100.0% 56.5%
4937697 4010.1.1.1 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.83 81.0 6.30e-01 100.0% 56.2%
4932689 4010.1.1.1 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1 0.83 80.0 6.38e-01 100.0% 60.7%
5000297 4010.1.1.0 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.83 79.0 6.03e-01 100.0% 56.9%
3204293 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.82 79.0 5.84e-01 100.0% 48.5%
3641572 3831.1.1.0 ↗ alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 0.67 35.0 4.17e-01 79.2% 73.3%
4888114 4010.1.1.2 ↗ a+b complex topology › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › N-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_1,RNA_pol_Rpb2_3 0.65 62.0 4.68e-01 100.0% 48.5%
3190527 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.58 23.0 2.85e-01 70.1% 56.0%
D4 medium residues 209-277_334-391
PDB
Domain cluster: rep: RNA_polymerase_beta_subunit__YP_009342128__Lymphocystis_disease_virus_Sa__1898060__D129-284
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7ob9B01 3.90.1110.10 Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2 0.88 81.0 6.92e-01 96.9% 97.9%
4qiwB04 3.90.1110.10 Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2 0.87 74.0 6.73e-01 89.0% 100.0%
1yqfB00 3.10.280.10 Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein 0.64 52.0 4.66e-01 87.4% 76.8%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.59 47.0 4.53e-01 84.3% 95.0%
2bs6A01 2.40.128.190 Mainly Beta › Beta Barrel › Lipocalin › 0.57 33.0 3.88e-01 79.5% 84.5%
1mrzB02 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.55 38.0 4.00e-01 92.9% 79.5%
3djaA01 1.20.920.70 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.55 33.0 3.20e-01 92.9% 51.7%
4h5bA00 3.30.1460.70 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.54 38.0 3.62e-01 73.2% 87.5%
2gsbA01 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.53 30.0 3.52e-01 80.3% 81.0%
2qpvA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 36.0 3.63e-01 89.8% 68.2%
2pwwA00 3.30.310.100 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › YugN-like 0.52 36.0 3.77e-01 80.3% 78.3%
1d4tA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.51 36.0 3.94e-01 82.7% 89.4%
3k1lA01 3.30.457.40 Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › 0.51 31.0 3.52e-01 81.1% 81.5%
6nu7A01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.51 41.0 3.15e-01 90.6% 90.5%
4n4bA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.50 43.0 3.17e-01 91.3% 47.3%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4994698 4041.1.1.0 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase 0.88 81.0 6.87e-01 96.9% 100.0%
3519803 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.88 82.0 6.98e-01 97.6% 99.5%
4958749 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.88 82.0 6.98e-01 97.6% 98.4%
4942210 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.88 79.0 7.01e-01 93.7% 100.0%
5044101 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.88 82.0 7.11e-01 97.6% 99.4%
4927221 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.87 80.0 7.02e-01 95.3% 98.9%
4946073 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.87 80.0 7.01e-01 95.3% 99.4%
4980641 4041.1.1.0 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase 0.87 80.0 6.90e-01 96.1% 98.4%
5027940 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.87 80.0 7.12e-01 96.1% 100.0%
4937698 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.87 80.0 7.19e-01 96.1% 98.2%
3592763 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.86 81.0 6.88e-01 97.6% 98.9%
4933430 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.86 80.0 7.03e-01 96.9% 100.0%
4973001 4041.1.1.0 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase 0.86 78.0 6.68e-01 95.3% 100.0%
5070259 4041.1.1.1 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.85 76.0 6.82e-01 93.7% 98.2%
4983207 4041.1.1.0 ↗ a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase 0.82 73.0 6.51e-01 94.5% 98.9%
3483806 295.1.1.3 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.62 43.0 4.06e-01 70.1% 100.0%
3364063 295.1.1.3 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.61 46.0 4.45e-01 78.0% 99.3%
3228051 295.1.1.3 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.61 30.0 3.96e-01 71.7% 89.2%
3866695 295.1.1.3 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.61 45.0 4.20e-01 76.4% 100.0%
3890928 295.1.1.3 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.60 49.0 4.37e-01 86.6% 91.1%
3241305 295.1.1.3 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.59 47.0 4.60e-01 84.3% 96.4%
4124004 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.58 26.0 3.54e-01 83.5% 83.1%
3929256 295.1.1.3 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.57 47.0 4.55e-01 86.6% 93.6%
5016556 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.55 34.0 3.88e-01 74.8% 84.4%
222386 241.1.1.6 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › YbjN 0.54 38.0 3.62e-01 73.2% 87.5%
4015773 216.1.1.0 ↗ a+b two layers › UBC-like › UBC-like › UBC-like 0.53 37.0 4.06e-01 97.6% 89.0%
4265925 3518.1.2.0 ↗ a+b two layers › putative RnfG subunit of electron transport complex › putative RnfG subunit of electron transport complex 0.53 43.0 4.12e-01 88.2% 98.0%
4602126 214.1.1.1 ↗ a+b two layers › SH2 › SH2 › SH2 › SH2 0.51 36.0 3.84e-01 79.5% 83.6%
2439577 214.1.1.0 ↗ a+b two layers › SH2 › SH2 › SH2 0.51 36.0 3.71e-01 72.4% 79.0%
D5 medium residues 278-333
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2yz0A00 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.61 42.0 3.24e-01 71.4% 30.4%
2kw3C00 6.10.290.30 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulatory factor X-associated C-terminal binding domain 0.54 37.0 3.62e-01 71.4% 71.0%
3u61D03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.51 40.0 3.53e-01 92.9% 81.3%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3457356 145.1.1.2 ↗ alpha arrays › F-box domain › F-box domain › F-box domain › Elongin_A 0.54 38.0 3.37e-01 76.8% 83.1%
3804512 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.53 40.0 3.81e-01 91.1% 68.6%
4173843 532.2.1.1 ↗ alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains › HrpJ 0.51 37.0 3.09e-01 80.4% 78.2%
D6 medium residues 497-551
PDB
D7 medium residues 552-623
PDB
Domain cluster: rep: DNA-directed_RNA_polymerase_subunit_beta__YP_003406778__Marseillevirus_marseillevirus__694581__D519-604
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1twfB05 3.90.1070.20 Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › 0.88 78.0 7.39e-01 93.1% 91.5%
6ruiB05 3.90.1070.20 Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › 0.86 75.0 6.84e-01 93.1% 91.3%
2pmzB05 3.90.1070.20 Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › 0.82 71.0 6.84e-01 93.1% 91.3%
1ze3D00 3.10.20.410 Alpha Beta › Roll › Ubiquitin-like (UB roll) › PapC, N-terminal domain 0.69 50.0 4.21e-01 75.0% 74.1%
1n6zA00 3.10.20.250 Alpha Beta › Roll › Ubiquitin-like (UB roll) › YML108W-like 0.68 49.0 4.36e-01 77.8% 81.9%
3u5eU00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.66 49.0 4.41e-01 80.6% 98.0%
1kqfB02 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 45.0 3.67e-01 72.2% 100.0%
1vx7X00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.63 47.0 4.28e-01 80.6% 100.0%
2m1mA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.62 48.0 4.20e-01 81.9% 95.3%
4orlA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 44.0 3.90e-01 79.2% 78.2%
2bw2A01 3.10.20.420 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Bypass-of-forespore C, N-terminal domain 0.58 41.0 4.47e-01 75.0% 100.0%
4bzaA01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.57 40.0 4.09e-01 100.0% 77.9%
1p65A00 6.10.140.90 Special › Helix non-globular › Helix Hairpins › 0.56 29.0 3.27e-01 87.5% 63.2%
2x8xX02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.56 43.0 4.28e-01 100.0% 80.3%
2af6A01 3.30.70.3180 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 43.0 3.62e-01 87.5% 86.3%
3jyyA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.55 41.0 3.36e-01 80.6% 91.0%
2b30A02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.55 47.0 4.11e-01 97.2% 90.8%
6j09A02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.54 43.0 4.24e-01 100.0% 80.8%
4jtmA00 3.55.50.30 Alpha Beta › 3-Layer(bab) Sandwich › Phage tail protein beta-alpha-beta fold › 0.54 44.0 4.29e-01 100.0% 81.5%
5e3xA00 1.10.1370.30 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › 0.53 45.0 2.74e-01 94.4% 74.4%
2qdfA02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.53 41.0 3.98e-01 100.0% 74.7%
1js3A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.52 41.0 3.83e-01 95.8% 67.0%
2kc1A00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 44.0 4.12e-01 95.8% 100.0%
4ol9A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 43.0 3.31e-01 93.1% 72.4%
3d37A02 3.55.50.10 Alpha Beta › 3-Layer(bab) Sandwich › Phage tail protein beta-alpha-beta fold › Baseplate protein-like domains 0.52 43.0 4.08e-01 91.7% 81.2%
2c60A01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.51 35.0 3.44e-01 72.2% 100.0%
3lmmA03 3.30.565.60 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › 0.50 40.0 3.19e-01 94.4% 63.2%
ECOD (67)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5054490 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.95 65.0 7.46e-01 70.8% 100.0%
4937778 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.94 67.0 7.64e-01 73.6% 100.0%
4942023 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.93 68.0 7.74e-01 75.0% 100.0%
3603406 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.92 66.0 7.59e-01 75.0% 100.0%
3491435 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.91 82.0 7.68e-01 94.4% 87.1%
5027955 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.91 66.0 7.49e-01 75.0% 100.0%
3306570 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.90 80.0 7.30e-01 93.1% 85.6%
3610294 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.89 79.0 7.25e-01 93.1% 83.3%
3637895 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.89 83.0 7.44e-01 98.6% 85.3%
4927222 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.89 81.0 7.26e-01 95.8% 86.3%
3654329 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.89 82.0 7.50e-01 97.2% 86.7%
5026627 4961.1.1.0 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.89 77.0 6.71e-01 90.3% 98.0%
3594275 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.89 78.0 7.17e-01 93.1% 84.4%
3721265 4961.1.1.2 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpa2_4 0.89 78.0 6.98e-01 93.1% 85.3%
5073048 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.88 80.0 7.31e-01 95.8% 85.6%
3575675 4961.1.1.2 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpa2_4 0.88 81.0 6.92e-01 98.6% 84.5%
4940801 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.88 64.0 7.29e-01 77.8% 100.0%
4994086 4961.1.1.0 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.87 78.0 7.30e-01 94.4% 85.9%
3401629 4961.1.1.2 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpa2_4 0.87 79.0 6.92e-01 95.8% 83.0%
3335720 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.87 75.0 6.93e-01 91.7% 82.2%
4980642 4961.1.1.0 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.87 75.0 7.47e-01 91.7% 93.3%
5062681 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.87 79.0 7.40e-01 97.2% 87.1%
4979469 4961.1.1.0 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.87 79.0 7.29e-01 97.2% 85.6%
4935989 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.87 78.0 7.17e-01 95.8% 83.3%
4939951 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.87 77.0 6.97e-01 95.8% 84.2%
3492372 4961.1.1.2 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpa2_4 0.87 78.0 6.62e-01 95.8% 84.5%
3258891 4961.1.1.2 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpa2_4 0.86 76.0 6.47e-01 94.4% 79.1%
3303495 4961.1.1.2 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpa2_4 0.86 74.0 6.28e-01 91.7% 76.4%
4150637 4961.1.1.2 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpa2_4 0.85 77.0 6.57e-01 97.2% 85.5%
5037577 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.85 73.0 6.59e-01 91.7% 88.4%
4946074 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.85 73.0 6.48e-01 93.1% 86.0%
5000299 4961.1.1.0 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.85 74.0 6.84e-01 94.4% 85.6%
4956726 4961.1.1.1 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.84 75.0 7.04e-01 94.4% 87.1%
4024672 4961.1.1.0 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.84 72.0 6.35e-01 91.7% 86.0%
3513013 4961.1.1.2 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpa2_4 0.83 75.0 6.73e-01 95.8% 86.3%
5059475 4961.1.1.0 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.82 72.0 6.82e-01 94.4% 91.8%
4932691 4961.1.1.0 ↗ a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.79 72.0 6.80e-01 97.2% 84.7%
3785086 870.1.1.1 ↗ a+b two layers › Hypothetical protein Yml108w › Hypothetical protein Yml108w › Hypothetical protein Yml108w › DUF1892 0.70 49.0 4.65e-01 73.6% 81.2%
5745 870.1.1.1 ↗ a+b two layers › Hypothetical protein Yml108w › Hypothetical protein Yml108w › Hypothetical protein Yml108w › DUF1892 0.68 49.0 4.36e-01 77.8% 81.9%
4989862 221.10.1.1 ↗ a+b two layers › beta-Grasp › FdhD/NarQ beta-grasp fold domain › FdhD/NarQ beta-grasp fold domain › FdhD-NarQ 0.63 45.0 4.60e-01 75.0% 84.3%
3595281 3715.1.1.0 ↗ a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e 0.63 48.0 4.10e-01 83.3% 85.8%
5008091 221.10.1.1 ↗ a+b two layers › beta-Grasp › FdhD/NarQ beta-grasp fold domain › FdhD/NarQ beta-grasp fold domain › FdhD-NarQ 0.63 45.0 4.57e-01 75.0% 82.9%
4960926 221.10.1.1 ↗ a+b two layers › beta-Grasp › FdhD/NarQ beta-grasp fold domain › FdhD/NarQ beta-grasp fold domain › FdhD-NarQ 0.63 44.0 4.76e-01 73.6% 96.7%
2106287 3715.1.1.1 ↗ a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal_L22e 0.62 46.0 4.22e-01 80.6% 100.0%
3706789 3715.1.1.1 ↗ a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal_L22e 0.62 48.0 4.04e-01 84.7% 82.4%
4854164 3715.1.1.1 ↗ a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal_L22e 0.60 46.0 4.17e-01 84.7% 100.0%
4951383 221.10.1.1 ↗ a+b two layers › beta-Grasp › FdhD/NarQ beta-grasp fold domain › FdhD/NarQ beta-grasp fold domain › FdhD-NarQ 0.60 43.0 4.17e-01 75.0% 70.0%
5075349 221.10.1.1 ↗ a+b two layers › beta-Grasp › FdhD/NarQ beta-grasp fold domain › FdhD/NarQ beta-grasp fold domain › FdhD-NarQ 0.60 43.0 4.41e-01 76.4% 84.3%
4970952 3715.1.1.1 ↗ a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal_L22e 0.60 49.0 4.69e-01 100.0% 78.8%
5020150 221.10.1.1 ↗ a+b two layers › beta-Grasp › FdhD/NarQ beta-grasp fold domain › FdhD/NarQ beta-grasp fold domain › FdhD-NarQ 0.59 43.0 4.08e-01 76.4% 69.4%
4460312 3121.1.1.0 ↗ a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.59 42.0 4.05e-01 76.4% 84.7%
4952589 221.10.1.1 ↗ a+b two layers › beta-Grasp › FdhD/NarQ beta-grasp fold domain › FdhD/NarQ beta-grasp fold domain › FdhD-NarQ 0.59 42.0 4.51e-01 76.4% 100.0%
4954187 221.10.1.1 ↗ a+b two layers › beta-Grasp › FdhD/NarQ beta-grasp fold domain › FdhD/NarQ beta-grasp fold domain › FdhD-NarQ 0.58 42.0 4.45e-01 76.4% 100.0%
5075317 221.10.1.0 ↗ a+b two layers › beta-Grasp › FdhD/NarQ beta-grasp fold domain › FdhD/NarQ beta-grasp fold domain 0.58 42.0 4.40e-01 76.4% 90.8%
4305209 3121.1.1.2 ↗ a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA_1 0.58 41.0 4.19e-01 76.4% 98.6%
4315663 4333.1.1.1 ↗ a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › Methylase_S 0.57 50.0 3.09e-01 95.8% 26.6%
4459724 221.9.1.1 ↗ a+b two layers › beta-Grasp › N-terminal domain of bypass of forespore C, BofC › N-terminal domain of bypass of forespore C, BofC › BOFC_N 0.57 41.0 4.27e-01 76.4% 86.2%
4522693 3121.1.1.2 ↗ a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA_1 0.57 41.0 3.92e-01 77.8% 85.9%
4846239 3070.1.1.12 ↗ a+b complex topology › N0 domain in phage tail proteins and secretins-like › N0 domain in phage tail proteins and secretins › N0 domain in phage tail proteins and secretins › Gp44-like_2nd 0.55 46.0 4.39e-01 97.2% 79.8%
4964858 2498.1.1.103 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SpoVR 0.55 43.0 2.82e-01 87.5% 23.7%
3273227 226.1.1.1 ↗ a+b two layers › POZ domain › POZ domain › POZ domain › BTB 0.53 41.0 3.17e-01 87.5% 36.7%
1070142 3070.1.1.11 ↗ a+b complex topology › N0 domain in phage tail proteins and secretins-like › N0 domain in phage tail proteins and secretins › N0 domain in phage tail proteins and secretins › type_II_gspD_N0 0.53 44.0 4.24e-01 93.1% 81.5%
4606766 3070.1.1.0 ↗ a+b complex topology › N0 domain in phage tail proteins and secretins-like › N0 domain in phage tail proteins and secretins › N0 domain in phage tail proteins and secretins 0.53 46.0 4.28e-01 98.6% 88.9%
4879386 101.1.2.93 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_Mga 0.52 42.0 4.12e-01 94.4% 82.1%
4299003 2498.1.1.103 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › SpoVR 0.52 40.0 2.81e-01 87.5% 29.1%
3952539 7581.1.1.1 ↗ a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N 0.52 39.0 2.64e-01 81.9% 31.6%
3672823 243.1.1.49 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF2358 0.51 36.0 2.94e-01 77.8% 60.6%
D8 medium residues 673-766
PDB
Domain cluster: representative
CATH (73)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.82 58.0 5.32e-01 100.0% 58.0%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.81 57.0 5.27e-01 98.9% 58.6%
3m7gA02 1.10.8.1010 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.76 47.0 4.77e-01 98.9% 62.1%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.76 40.0 3.36e-01 100.0% 31.2%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 43.0 4.34e-01 100.0% 57.4%
1kyoF00 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.73 33.0 3.67e-01 100.0% 54.1%
2yinA03 1.20.58.740 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C 0.72 40.0 3.61e-01 100.0% 40.6%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 58.0 4.08e-01 100.0% 29.1%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.72 58.0 5.97e-01 100.0% 88.9%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.69 59.0 4.13e-01 94.7% 87.8%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 47.0 4.51e-01 92.6% 60.0%
3aeiA00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 58.0 5.89e-01 98.9% 91.5%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.69 55.0 5.64e-01 100.0% 88.8%
3zbhA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.69 51.0 5.19e-01 100.0% 81.1%
1qv9A02 6.10.140.120 Special › Helix non-globular › Helix Hairpins › 0.69 46.0 4.52e-01 91.5% 63.1%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 50.0 4.95e-01 97.9% 72.3%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.68 46.0 3.50e-01 100.0% 30.1%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.67 54.0 5.10e-01 98.9% 71.4%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 40.0 3.58e-01 80.9% 43.0%
2gtaA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.67 44.0 4.36e-01 95.7% 63.9%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 47.0 4.08e-01 98.9% 47.6%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.66 57.0 5.21e-01 98.9% 81.7%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 46.0 4.58e-01 95.7% 69.1%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 48.0 4.56e-01 100.0% 65.5%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.65 56.0 5.64e-01 100.0% 91.5%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 51.0 4.66e-01 81.9% 96.7%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.65 49.0 5.08e-01 100.0% 86.2%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.65 54.0 3.73e-01 100.0% 27.5%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 58.0 4.98e-01 100.0% 64.7%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.64 50.0 5.30e-01 98.9% 95.1%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 60.0 5.83e-01 100.0% 94.2%
5nx5B00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.64 55.0 3.79e-01 93.6% 29.5%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.64 39.0 4.05e-01 90.4% 65.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.64 43.0 4.05e-01 100.0% 56.4%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.63 47.0 5.12e-01 92.6% 92.5%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 48.0 4.70e-01 100.0% 74.8%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.63 48.0 5.06e-01 98.9% 91.5%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 52.0 5.14e-01 95.7% 83.0%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 47.0 5.13e-01 100.0% 97.4%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.63 59.0 4.97e-01 100.0% 83.6%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 58.0 4.24e-01 100.0% 39.8%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 48.0 4.61e-01 88.3% 71.3%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.62 48.0 4.17e-01 100.0% 54.2%
2k8oA00 1.20.5.2120 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.62 28.0 3.43e-01 95.7% 61.7%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.62 41.0 3.55e-01 100.0% 41.9%
2ieqA00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.62 51.0 5.25e-01 100.0% 94.3%
1gpjA03 1.10.1200.70 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glutamyl tRNA-reductase dimerization domain 0.61 36.0 3.80e-01 86.2% 64.7%
4wpcA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.61 56.0 3.92e-01 100.0% 34.3%
4akvA02 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.61 53.0 4.13e-01 100.0% 46.3%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.61 54.0 5.37e-01 97.9% 92.7%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.60 44.0 4.83e-01 97.9% 95.9%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 48.0 4.74e-01 100.0% 82.8%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.59 52.0 4.30e-01 100.0% 55.3%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 49.0 4.32e-01 92.6% 61.0%
4iggB06 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 46.0 3.65e-01 86.2% 61.4%
4jioA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.59 54.0 4.46e-01 98.9% 64.6%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.59 40.0 4.51e-01 94.7% 97.1%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 51.0 4.06e-01 100.0% 48.6%
8gccA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.59 51.0 4.95e-01 94.7% 100.0%
2x0cA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.58 50.0 4.11e-01 96.8% 79.2%
2xgjA04 1.20.1500.20 Mainly Alpha › Up-down Bundle › YheA-like fold › 0.58 52.0 4.63e-01 96.8% 100.0%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 53.0 3.92e-01 100.0% 44.4%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 47.0 4.50e-01 98.9% 75.2%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.57 50.0 4.99e-01 98.9% 92.9%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.56 43.0 4.55e-01 97.9% 89.4%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.56 40.0 3.93e-01 91.5% 68.6%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 47.0 3.53e-01 100.0% 37.1%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 47.0 3.87e-01 100.0% 52.6%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.54 39.0 3.56e-01 78.7% 87.4%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 34.0 3.57e-01 95.7% 71.4%
3tbiB02 6.10.140.1670 Special › Helix non-globular › Helix Hairpins › 0.53 48.0 4.77e-01 98.9% 95.0%
7r0kB01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.51 38.0 2.83e-01 79.8% 80.6%
4hwdD00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.50 38.0 3.92e-01 79.8% 95.6%
ECOD (80)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4179150 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.84 53.0 3.24e-01 100.0% 11.5%
3286912 632.18.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.82 45.0 4.55e-01 100.0% 53.7%
3440913 4006.1.1.0 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.78 57.0 4.93e-01 100.0% 51.9%
3924662 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 47.0 4.75e-01 100.0% 62.1%
3605635 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.74 58.0 5.25e-01 100.0% 61.6%
3277724 150.5.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.74 57.0 5.76e-01 100.0% 80.0%
4983118 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.72 59.0 5.88e-01 100.0% 84.2%
3960437 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.72 57.0 4.57e-01 98.9% 45.9%
4142346 5086.1.1.87 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.71 53.0 5.03e-01 100.0% 66.4%
3254719 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.71 48.0 4.83e-01 98.9% 68.4%
3278767 2004.1.1.567 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 0.71 60.0 3.50e-01 100.0% 12.4%
3483996 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 52.0 4.92e-01 100.0% 65.5%
3253767 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.70 63.0 5.28e-01 100.0% 58.7%
3595205 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.70 41.0 3.09e-01 93.6% 25.0%
3503590 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.70 62.0 5.69e-01 100.0% 75.7%
5076440 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.69 43.0 4.24e-01 97.9% 59.0%
981547 150.5.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.68 50.0 5.24e-01 100.0% 83.9%
3937465 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.68 46.0 3.54e-01 100.0% 30.7%
3742018 7094.1.1.2 ↗ alpha bundles › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › LIS_MGM1 0.67 59.0 5.92e-01 100.0% 91.6%
4214119 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.66 58.0 4.04e-01 100.0% 31.6%
3242683 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.66 43.0 4.39e-01 95.7% 67.8%
3373782 6155.1.1.2 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.66 43.0 4.03e-01 95.7% 53.9%
3596922 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.65 57.0 4.69e-01 100.0% 55.1%
4203309 223.1.1.0 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains 0.65 48.0 3.07e-01 98.9% 16.3%
3961947 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 54.0 4.50e-01 100.0% 53.5%
3988700 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.65 57.0 4.57e-01 100.0% 71.3%
3478220 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.65 56.0 5.53e-01 100.0% 87.0%
3615971 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 56.0 4.39e-01 100.0% 45.8%
3594486 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 58.0 5.28e-01 98.9% 74.2%
4059164 6155.1.1.8 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › Pyr4-TMTC 0.64 43.0 4.27e-01 95.7% 65.0%
3221606 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.64 55.0 5.26e-01 96.8% 81.0%
3675934 3755.3.1.374 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › UCP030365 0.64 56.0 4.58e-01 100.0% 54.4%
4951835 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 60.0 5.37e-01 100.0% 77.6%
3381175 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.64 55.0 4.03e-01 100.0% 36.3%
3727276 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 41.0 4.23e-01 97.9% 69.7%
4336245 2004.1.1.567 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 0.63 59.0 3.47e-01 100.0% 54.5%
3596744 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.63 51.0 5.33e-01 98.9% 94.1%
3804937 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.63 56.0 4.61e-01 94.7% 100.0%
4086322 5086.1.1.205 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PF30209 0.63 56.0 4.54e-01 100.0% 53.9%
4862474 3291.1.1.4 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 0.63 51.0 4.46e-01 100.0% 58.5%
4414254 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 58.0 4.05e-01 100.0% 33.6%
3635376 3755.3.1.298 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ING 0.62 54.0 4.73e-01 98.9% 64.4%
3365701 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.61 57.0 5.41e-01 100.0% 98.2%
5074535 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 57.0 5.19e-01 100.0% 77.5%
3475021 4177.1.1.16 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FAP206 0.61 57.0 3.85e-01 100.0% 30.0%
3496446 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.61 50.0 4.22e-01 100.0% 53.5%
5031839 2004.1.1.198 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.61 57.0 3.63e-01 100.0% 23.1%
5025381 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.61 57.0 3.81e-01 100.0% 29.4%
3192129 3755.1.1.0 ↗ alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.61 57.0 4.26e-01 98.9% 45.7%
4673482 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 56.0 4.38e-01 100.0% 76.8%
3795092 622.4.1.0 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.61 52.0 4.59e-01 95.7% 64.4%
3787585 5086.1.1.87 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.61 52.0 5.01e-01 100.0% 82.9%
4676422 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.60 52.0 4.18e-01 100.0% 49.7%
3945620 5086.1.1.85 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.60 50.0 5.19e-01 97.9% 93.3%
3720276 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.60 52.0 3.57e-01 100.0% 28.4%
4403218 3291.1.1.82 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.60 51.0 4.96e-01 100.0% 82.9%
3184140 5086.1.1.87 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.60 51.0 4.76e-01 100.0% 75.7%
3235297 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.59 55.0 4.34e-01 100.0% 83.8%
4025636 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.59 55.0 4.56e-01 100.0% 74.7%
3883768 5086.1.1.101 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › SH3BP5 0.59 54.0 4.88e-01 100.0% 75.2%
3904356 3755.3.1.9 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › SH3BP5 0.59 54.0 4.14e-01 100.0% 45.9%
3636338 192.2.1.18 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.59 50.0 4.54e-01 100.0% 69.6%
3723606 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.58 54.0 3.40e-01 100.0% 21.1%
3239816 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 53.0 4.12e-01 100.0% 61.0%
3541873 3755.3.1.297 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 0.58 51.0 4.46e-01 100.0% 65.0%
3945729 604.32.1.0 ↗ alpha bundles › Spectrin repeat-like › Recombination protein uvsY › Recombination protein uvsY 0.58 53.0 4.74e-01 100.0% 72.3%
3755586 3291.1.1.118 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › KIF9 0.58 51.0 4.44e-01 100.0% 65.0%
3224742 3755.3.1.9 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › SH3BP5 0.57 49.0 3.75e-01 100.0% 40.9%
3616476 4177.1.1.6 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3_WASP_bdg 0.57 52.0 3.95e-01 100.0% 56.7%
3766955 192.7.1.17 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › FAM186A-B_C 0.57 51.0 4.37e-01 100.0% 62.8%
3707454 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.57 52.0 5.20e-01 98.9% 97.9%
3719459 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.57 50.0 3.98e-01 100.0% 49.2%
3958796 150.8.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE 0.56 45.0 4.13e-01 98.9% 66.7%
4974533 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.56 51.0 4.48e-01 97.9% 100.0%
4025289 192.29.1.197 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4110 0.56 46.0 4.82e-01 97.9% 100.0%
3940634 601.1.3.8 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › PF27524 0.56 50.0 4.38e-01 100.0% 82.1%
3279432 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.55 49.0 4.73e-01 100.0% 86.4%
4969095 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 47.0 3.11e-01 100.0% 30.6%
4431938 507.1.1.7 ↗ alpha arrays › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › PF30523 0.52 45.0 3.48e-01 97.9% 43.4%
3369128 2004.1.1.615 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23, AAA_29 0.51 45.0 2.79e-01 100.0% 33.9%
D9 medium residues 854-874_981-1123
PDB
Domain cluster: rep: KU935715.1__AND75470.1__ME3_309__00309__D264-326_420-534
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00562.34 best RNA_pol_Rpb2_6 183.6 9.20e-54 87.8% 37.5%
PF00562.34 RNA_pol_Rpb2_6 24.0 2.80e-05 18.3% 6.7%
D10 medium residues 1176-1244
PDB
Domain cluster: rep: IMGVR_UViG_3300025836_000142-3300025836-Ga0209748_10097103__D124-188
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5w5yB08 3.90.1800.10 Alpha Beta › Alpha-Beta Complex › DCoH-like › RNA polymerase alpha subunit dimerisation domain 0.82 73.0 5.64e-01 97.1% 72.9%
7ob9B02 3.90.1800.10 Alpha Beta › Alpha-Beta Complex › DCoH-like › RNA polymerase alpha subunit dimerisation domain 0.81 62.0 5.38e-01 81.2% 63.7%
2giaB00 2.30.31.40 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › 0.58 40.0 3.16e-01 72.5% 75.3%
3s8sA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.53 43.0 3.79e-01 91.3% 100.0%
1w7oA00 3.90.10.10 Alpha Beta › Alpha-Beta Complex › Cytochrome C3 › Cytochrome C3 0.53 36.0 3.15e-01 72.5% 85.6%
2xqyA01 3.30.500.50 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › 0.52 35.0 2.70e-01 72.5% 89.9%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4972999 4043.1.1.0 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.89 82.0 6.71e-01 100.0% 61.7%
4946078 4043.1.1.0 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.88 78.0 6.44e-01 94.2% 60.9%
3417299 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.88 79.0 6.25e-01 95.7% 60.8%
5054775 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.87 81.0 6.57e-01 100.0% 59.2%
1223288 4246.1.1.0 ↗ a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit 0.85 72.0 7.50e-01 91.3% 100.0%
3603405 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.85 78.0 6.13e-01 100.0% 60.0%
3695558 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.85 76.0 5.74e-01 97.1% 70.3%
3712063 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.85 79.0 6.16e-01 100.0% 60.0%
5070342 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.84 76.0 6.89e-01 97.1% 78.9%
1108098 4043.1.1.1 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 0.84 76.0 5.73e-01 97.1% 68.2%
4818395 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.84 72.0 6.65e-01 91.3% 84.7%
3599423 4043.1.1.0 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.83 75.0 5.91e-01 95.7% 60.0%
3182259 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.83 76.0 5.51e-01 98.6% 75.4%
3925293 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.82 75.0 5.81e-01 100.0% 65.0%
2754226 4043.1.1.1 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 0.81 71.0 5.83e-01 95.7% 56.2%
4932695 4043.1.1.2 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 0.81 74.0 6.05e-01 100.0% 58.3%
7620 4043.1.1.1 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 0.79 71.0 5.96e-01 97.1% 62.2%
1879234 4043.1.1.0 ↗ a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase 0.78 70.0 5.64e-01 97.1% 55.1%
3197773 10.12.1.52 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_8 0.66 46.0 2.97e-01 88.4% 16.1%
4942235 213.1.1.0 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) 0.59 34.0 2.86e-01 88.4% 34.8%
4222633 377.1.1.0 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.55 41.0 4.17e-01 95.7% 78.6%
5050596 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.53 29.0 2.89e-01 75.4% 50.0%
3680043 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.53 43.0 3.59e-01 95.7% 51.7%
5015962 375.1.1.64 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › RUBY_RBDX 0.52 36.0 4.03e-01 84.1% 100.0%
5000817 239.1.1.5 ↗ beta barrels › Ribosomal protein L25-like › Ribosomal protein L25-like › Ribosomal protein L25-like › tRNA-synt_1c_C 0.51 43.0 3.81e-01 95.7% 92.4%