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DNA-directed_RNA_polymerase_subunit_alpha

Euk-Vir

Salmon_gill_poxvirus

DNA-directed_RNA_polymerase_subunit_alpha__YP_009162537__Salmon_gill_poxvirus__1680908

Identity

Accession:
YP_009162537 ↗
Protein ID:
DNA-directed_RNA_polymerase_subunit_alpha
Kingdom:
euk

Quality

70.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D2 high residues 474-592
PDB
D3 high residues 812-921
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3oreA01 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.57 25.0 3.16e-01 94.5% 66.7%
3kdrA03 3.30.1120.70 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › 0.55 21.0 2.98e-01 75.5% 72.0%
2gtvX00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.54 39.0 4.08e-01 98.2% 81.7%
1b10A00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.52 40.0 4.12e-01 97.3% 86.5%
2gtaA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.50 36.0 3.78e-01 95.5% 83.5%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4887311 4957.1.1.0 a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit 0.88 77.0 7.35e-01 100.0% 80.2%
3268058 4957.1.1.1 a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit › RNA_pol_Rpb1_6 0.80 75.0 6.05e-01 100.0% 88.7%
5069732 545.1.2.0 alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain 0.57 39.0 4.48e-01 88.2% 97.5%
3742790 621.1.1.7 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 0.51 37.0 3.97e-01 100.0% 86.3%
D4 medium residues 61-85_200-271
PDB
D5 medium residues 307-457
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00623.26 best RNA_pol_Rpb1_2 79.1 6.50e-22 98.0% 90.4%
D6 medium residues 605-742
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05000.23 best RNA_pol_Rpb1_4 61.1 1.20e-16 79.0% 98.1%
D7 medium residues 998-1020_1117-1202
PDB
D8 medium residues 1021-1116
PDB
D9 medium residues 1236-1277
PDB