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DNA-directed_RNA_polymerase_subunit_alpha
Euk-VirTunisvirus_fontaine2
DNA-directed_RNA_polymerase_subunit_alpha__YP_009507159__Tunisvirus_fontaine2__1421067
Identity
- Accession:
- YP_009507159 ↗
- Protein ID:
- DNA-directed_RNA_polymerase_subunit_alpha
- Kingdom:
- euk
Quality
77.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Marseilleviridae›
Losannavirus›
Tunisvirus_fontaine2
TaxID: 1421067
Cluster
View cluster (8 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 86-217
Domain cluster:
rep: DNA-directed_RNA_polymerase_II_largest_subunit__YP_010084808__Shrimp_hemocyte_iridescent_virus__2039780__D81-188
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04997.18 best | RNA_pol_Rpb1_1 | 40.5 | 3.00e-10 | 93.9% | 36.5% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3dbaA00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.51 | 35.0 | 3.27e-01 | 70.5% | 97.1% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4803223 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.86 | 70.0 | 5.21e-01 | 91.7% | 37.3% |
| 3487002 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.84 | 75.0 | 5.26e-01 | 91.7% | 40.9% |
| 4648965 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.84 | 74.0 | 5.31e-01 | 91.7% | 37.0% |
| 4380798 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.83 | 72.0 | 5.19e-01 | 90.2% | 38.5% |
| 4023558 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.82 | 73.0 | 5.17e-01 | 91.7% | 42.6% |
| 3610049 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.82 | 73.0 | 5.17e-01 | 91.7% | 42.0% |
| 3393665 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.82 | 72.0 | 5.09e-01 | 90.9% | 43.1% |
| 3596876 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.82 | 71.0 | 5.07e-01 | 90.2% | 45.0% |
| 4871979 | 4246.1.1.4 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 | 0.82 | 69.0 | 5.79e-01 | 91.7% | 55.2% |
| 3717545 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.82 | 71.0 | 5.08e-01 | 90.2% | 45.7% |
| 4027469 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.81 | 70.0 | 5.04e-01 | 89.4% | 39.1% |
| 3348138 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.81 | 70.0 | 5.01e-01 | 90.2% | 41.4% |
| 3699234 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.81 | 68.0 | 5.50e-01 | 87.9% | 64.4% |
| 3166784 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.81 | 71.0 | 4.97e-01 | 91.7% | 42.4% |
| 4809191 | 4246.1.1.4 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_2, RNA_pol_Rpb1_1 | 0.80 | 63.0 | 5.14e-01 | 81.8% | 60.3% |
| 3596097 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.80 | 71.0 | 5.12e-01 | 91.7% | 38.1% |
| 5026630 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.80 | 68.0 | 4.96e-01 | 90.2% | 36.3% |
| 3185006 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.78 | 69.0 | 4.93e-01 | 91.7% | 40.3% |
| 4079870 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.76 | 71.0 | 5.05e-01 | 98.5% | 40.0% |
| 4069919 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.75 | 64.0 | 4.31e-01 | 90.2% | 49.8% |
| 3714090 | 4246.1.1.0 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit | 0.74 | 67.0 | 4.46e-01 | 96.2% | 48.0% |
| 3618547 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.73 | 62.0 | 4.25e-01 | 90.2% | 54.5% |
| 3550786 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.72 | 63.0 | 4.32e-01 | 91.7% | 47.8% |
| 3409846 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.72 | 62.0 | 4.29e-01 | 91.7% | 46.1% |
| 3928969 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.71 | 63.0 | 4.27e-01 | 92.4% | 48.1% |
| 4801458 | 4246.1.1.2 ↗ | a+b complex topology › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › N-terminal domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_1 | 0.71 | 57.0 | 4.38e-01 | 90.2% | 40.1% |
| 3821839 | 192.8.1.59 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › ATG14 | 0.54 | 38.0 | 2.91e-01 | 71.2% | 57.6% |
D2
medium
residues 11-85
Domain cluster:
rep: RNA_polymerase_RPB1_large_subunit__YP_009345156__Noumeavirus__1955558__D1-73
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04997.18 best | RNA_pol_Rpb1_1 | 60.7 | 2.20e-16 | 100.0% | 22.1% |
D3
medium
residues 238-281_297-348
Domain cluster:
rep: DNA-directed_RNA_polymerase_subunit_alpha__YP_003406803__Marseillevirus_marseillevirus__694581__D272-293_307-365
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04997.18 best | RNA_pol_Rpb1_1 | 59.4 | 5.40e-16 | 94.8% | 32.4% |
D4
medium
residues 349-476
Domain cluster:
rep: DNA-directed_RNA_polymerase_subunit_alpha__YP_009238536__Brazilian_marseillevirus__1813599__D353-470
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00623.26 best | RNA_pol_Rpb1_2 | 82.3 | 7.00e-23 | 100.0% | 79.5% |