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DNA-directed_RNA_polymerase_subunit_beta

Euk-Vir

Marseillevirus_marseillevirus

DNA-directed_RNA_polymerase_subunit_beta__YP_003406778__Marseillevirus_marseillevirus__694581

Identity

Accession:
YP_003406778 ↗
Protein ID:
DNA-directed_RNA_polymerase_subunit_beta
Kingdom:
euk

Quality

74.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D3 medium residues 72-166
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04563.21 best RNA_pol_Rpb2_1 42.5 7.80e-11 96.8% 37.4%
D4 medium residues 452-518_684-768
PDB
D5 medium residues 519-604
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04566.19 best RNA_pol_Rpb2_4 47.7 1.90e-12 62.8% 87.1%
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pmzB05 3.90.1070.20 Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › 0.91 77.0 8.02e-01 88.4% 100.0%
1twfB05 3.90.1070.20 Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › 0.87 73.0 7.47e-01 88.4% 100.0%
4b0eD00 3.10.20.410 Alpha Beta › Roll › Ubiquitin-like (UB roll) › PapC, N-terminal domain 0.64 45.0 4.27e-01 72.1% 82.0%
1ze3D00 3.10.20.410 Alpha Beta › Roll › Ubiquitin-like (UB roll) › PapC, N-terminal domain 0.63 44.0 3.97e-01 72.1% 74.1%
1n6zA00 3.10.20.250 Alpha Beta › Roll › Ubiquitin-like (UB roll) › YML108W-like 0.63 43.0 4.08e-01 72.1% 83.8%
3tm4A01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.62 36.0 2.80e-01 86.0% 25.9%
1mhxA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.62 36.0 4.02e-01 89.5% 75.4%
2x8xX01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.59 41.0 4.30e-01 90.7% 81.6%
7arcC01 3.30.460.80 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › NADH:ubiquinone oxidoreductase Nqo5 subunit 0.58 46.0 4.04e-01 88.4% 69.6%
5efrA02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.57 41.0 4.34e-01 89.5% 89.0%
4qkyA02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.57 40.0 4.23e-01 90.7% 86.5%
3adyA00 3.55.50.60 Alpha Beta › 3-Layer(bab) Sandwich › Phage tail protein beta-alpha-beta fold › DotD protein 0.56 43.0 4.11e-01 82.6% 71.6%
4bzaA02 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.55 42.0 4.24e-01 88.4% 81.6%
1mpyA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.54 38.0 3.29e-01 76.7% 76.5%
3v8vA01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.53 42.0 3.16e-01 84.9% 68.9%
4k3bA04 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.53 39.0 4.07e-01 95.3% 88.5%
4k3cA01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.51 38.0 3.89e-01 88.4% 82.9%
2qdfA03 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.51 37.0 3.89e-01 89.5% 85.7%
3og5A01 3.10.20.310 Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac 0.51 37.0 3.81e-01 88.4% 80.0%
7q5yB01 3.30.460.80 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › NADH:ubiquinone oxidoreductase Nqo5 subunit 0.51 41.0 3.73e-01 91.9% 68.3%
2kc8A00 3.30.2310.20 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › RelE-like 0.50 38.0 3.71e-01 90.7% 72.6%
2ba1D01 3.30.230.70 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain 0.50 40.0 2.97e-01 87.2% 54.3%
2ghfA01 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.50 35.0 3.55e-01 75.6% 96.6%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5073048 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.95 89.0 8.78e-01 97.7% 100.0%
4979469 4961.1.1.0 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.94 89.0 8.80e-01 98.8% 100.0%
3637895 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.94 90.0 8.67e-01 100.0% 98.9%
4946074 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.94 86.0 8.06e-01 95.3% 99.0%
4933431 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.94 86.0 8.45e-01 95.3% 100.0%
5062681 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.93 87.0 8.75e-01 96.5% 100.0%
3306570 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.93 86.0 8.44e-01 95.3% 100.0%
3594275 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.93 85.0 8.42e-01 95.3% 98.9%
3335720 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.93 84.0 8.31e-01 94.2% 98.9%
3491435 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.93 84.0 8.53e-01 94.2% 100.0%
4994086 4961.1.1.0 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.93 85.0 8.62e-01 95.3% 100.0%
3610294 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.93 85.0 8.38e-01 95.3% 97.8%
5059475 4961.1.1.0 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.93 80.0 8.10e-01 89.5% 100.0%
3410221 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.93 85.0 8.35e-01 95.3% 100.0%
4927222 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.93 86.0 8.32e-01 97.7% 100.0%
4980642 4961.1.1.0 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.92 76.0 8.10e-01 84.9% 100.0%
1511443 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.92 85.0 8.41e-01 96.5% 100.0%
5000299 4961.1.1.0 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.92 82.0 8.09e-01 93.0% 100.0%
5037577 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.92 81.0 7.79e-01 91.9% 100.0%
4888116 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.92 68.0 6.93e-01 76.7% 85.7%
3517397 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.92 79.0 7.95e-01 89.5% 100.0%
3231491 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.91 87.0 8.35e-01 100.0% 98.9%
3654329 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.91 87.0 8.52e-01 98.8% 100.0%
4935989 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.90 83.0 8.19e-01 96.5% 100.0%
5026627 4961.1.1.0 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.90 66.0 6.21e-01 75.6% 99.0%
4939951 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.90 82.0 7.94e-01 96.5% 100.0%
4956726 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.90 81.0 8.17e-01 94.2% 100.0%
4855745 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.89 78.0 7.33e-01 91.9% 84.2%
3721265 4961.1.1.2 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpa2_4 0.87 78.0 7.51e-01 95.3% 100.0%
4948672 4961.1.1.1 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 0.85 82.0 6.68e-01 100.0% 67.1%
4932691 4961.1.1.0 a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit 0.81 74.0 7.47e-01 96.5% 100.0%
4379866 3121.1.1.0 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.65 43.0 4.77e-01 89.5% 89.2%
3165534 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.65 44.0 4.72e-01 89.5% 81.3%
3983695 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.64 43.0 4.42e-01 91.9% 72.5%
3946104 4212.1.1.1 beta barrels › FimD N-terminal domain-like › FimD N-terminal domain-like › FimD N-terminal domain-like › PapC_N 0.64 44.0 4.22e-01 72.1% 79.0%
3257275 3121.1.1.0 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.63 43.0 4.65e-01 90.7% 85.7%
3979412 4212.1.1.1 beta barrels › FimD N-terminal domain-like › FimD N-terminal domain-like › FimD N-terminal domain-like › PapC_N 0.63 44.0 4.24e-01 72.1% 87.4%
5050501 3715.1.1.1 a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal_L22e 0.61 51.0 5.02e-01 93.0% 85.3%
4592695 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.60 41.0 4.37e-01 95.3% 82.7%
119486 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.60 43.0 4.42e-01 94.2% 81.2%
3387643 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.59 44.0 4.60e-01 87.2% 85.0%
4673176 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.58 41.0 4.32e-01 91.9% 85.3%
4407101 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.58 41.0 4.29e-01 89.5% 85.3%
4027954 3121.1.1.0 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.57 43.0 4.24e-01 93.0% 75.6%
3970584 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.57 40.0 4.05e-01 95.3% 74.1%
3654654 3121.1.1.0 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain 0.57 42.0 4.26e-01 93.0% 80.0%
1731820 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.57 41.0 4.25e-01 91.9% 83.7%
4995927 3715.1.1.0 a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e 0.56 48.0 4.76e-01 95.3% 92.2%
3972388 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.56 42.0 4.30e-01 93.0% 86.3%
3494854 221.3.1.5 a+b two layers › beta-Grasp › Immunoglobulin-binding domains › Immunoglobulin-binding domains › Zn_SUZ12 0.56 45.0 4.28e-01 88.4% 93.2%
4241517 3070.1.1.6 a+b complex topology › N0 domain in phage tail proteins and secretins-like › N0 domain in phage tail proteins and secretins › N0 domain in phage tail proteins and secretins › TcpQ 0.55 43.0 4.49e-01 84.9% 91.3%
4528693 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.54 41.0 4.22e-01 89.5% 86.3%
2547935 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.53 40.0 4.04e-01 93.0% 79.8%
4085807 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.53 40.0 4.08e-01 91.9% 83.5%
4542622 3121.1.1.1 a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA 0.51 40.0 3.99e-01 88.4% 86.7%
3386504 2003.1.5.49 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_30 0.50 35.0 2.63e-01 73.3% 83.3%
D6 medium residues 605-683
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04567.23 best RNA_pol_Rpb2_5 41.5 2.70e-10 57.0% 100.0%
D7 medium residues 769-782_996-1056_1103-1156
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00562.34 best RNA_pol_Rpb2_6 104.2 1.20e-29 93.8% 30.6%
D8 medium residues 813-861
PDB