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DNA_Polymerase
Euk-VirAlcelaphine_gammaherpesvirus_1
DNA_Polymerase__NP_065512__Alcelaphine_gammaherpesvirus_1__35252
Identity
- Accession:
- NP_065512 ↗
- Protein ID:
- DNA_Polymerase
- Kingdom:
- euk
Quality
84.7
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Macavirus›
Alcelaphine_gammaherpesvirus_1
TaxID: 35252
Cluster
View cluster (158 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 310-526
Domain cluster:
rep: DNA_polymerase_catalytic_subunit__YP_401712__Human_gammaherpesvirus_4__10376__D288-457
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF13482.13 best | RNase_H_2 | 25.1 | 2.20e-05 | 83.9% | 89.1% |
| PF03104.26 | DNA_pol_B_exo1 | 173.7 | 6.20e-51 | 77.4% | 74.0% |
D2
medium
residues 576-605_735-841
Domain cluster:
rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 111.7 | 5.40e-32 | 79.6% | 24.1% |
| PF00136.27 | DNA_pol_B | 34.1 | 2.00e-08 | 22.6% | 6.4% |
D3
medium
residues 606-652_715-734
Domain cluster:
rep: DNA_polymerase_catalytic_subunit__YP_009342373__Spheniscid_alphaherpesvirus_1__2560777__D710-763
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 44.3 | 1.60e-11 | 71.6% | 9.9% |
D4
medium
residues 653-714
Domain cluster:
rep: DNA_polymerase__YP_008052566__Phaeocystis_globosa_virus__251749__D724-746_869-928
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 90.7 | 1.30e-25 | 100.0% | 13.7% |
CATH (71)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4fvmA06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.99 | 74.0 | 8.49e-01 | 77.4% | 100.0% |
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.94 | 89.0 | 6.42e-01 | 100.0% | 40.5% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.93 | 83.0 | 8.50e-01 | 96.8% | 100.0% |
| 4hb1A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.92 | 63.0 | 7.42e-01 | 71.0% | 100.0% |
| 2a26B01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.91 | 62.0 | 7.39e-01 | 72.6% | 100.0% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.90 | 75.0 | 7.03e-01 | 87.1% | 76.7% |
| 1vjxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.90 | 73.0 | 5.32e-01 | 85.5% | 36.2% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.89 | 66.0 | 7.47e-01 | 83.9% | 100.0% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.89 | 73.0 | 5.83e-01 | 87.1% | 49.1% |
| 1z0jB00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.89 | 66.0 | 7.31e-01 | 77.4% | 96.1% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.88 | 65.0 | 6.19e-01 | 82.3% | 67.6% |
| 4r42A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.88 | 74.0 | 5.06e-01 | 88.7% | 30.5% |
| 1wrdA00 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.88 | 72.0 | 6.09e-01 | 87.1% | 55.1% |
| 2qtfA02 | 6.10.250.2860 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.88 | 63.0 | 7.16e-01 | 77.4% | 97.9% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.88 | 73.0 | 4.95e-01 | 87.1% | 29.5% |
| 1xioA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.87 | 74.0 | 4.92e-01 | 90.3% | 27.2% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.87 | 74.0 | 6.54e-01 | 88.7% | 67.9% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.86 | 65.0 | 6.04e-01 | 80.6% | 65.3% |
| 1jkvA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.86 | 71.0 | 4.81e-01 | 87.1% | 27.4% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.86 | 76.0 | 5.79e-01 | 95.2% | 50.7% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.86 | 70.0 | 4.59e-01 | 87.1% | 23.6% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.86 | 68.0 | 6.68e-01 | 85.5% | 85.1% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.85 | 70.0 | 5.96e-01 | 87.1% | 58.9% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.85 | 70.0 | 7.22e-01 | 85.5% | 91.4% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.85 | 67.0 | 5.71e-01 | 82.3% | 57.0% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.85 | 70.0 | 5.90e-01 | 87.1% | 58.8% |
| 1pd3A00 | 1.10.287.230 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.85 | 66.0 | 7.00e-01 | 82.3% | 100.0% |
| 6z01B03 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.85 | 72.0 | 5.23e-01 | 91.9% | 36.4% |
| 3nkzA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.85 | 72.0 | 6.14e-01 | 91.9% | 61.9% |
| 2r9iA00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.85 | 71.0 | 6.76e-01 | 88.7% | 81.7% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.84 | 78.0 | 5.74e-01 | 100.0% | 49.7% |
| 3rkoG00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 68.0 | 5.72e-01 | 87.1% | 55.0% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.84 | 74.0 | 5.46e-01 | 93.5% | 76.4% |
| 2rpaA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.84 | 67.0 | 6.20e-01 | 85.5% | 68.8% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 68.0 | 5.75e-01 | 87.1% | 62.2% |
| 3anwA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 68.0 | 5.46e-01 | 87.1% | 53.1% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.83 | 66.0 | 6.14e-01 | 83.9% | 70.7% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.83 | 69.0 | 6.38e-01 | 87.1% | 73.7% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.83 | 66.0 | 6.71e-01 | 85.5% | 88.5% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.83 | 71.0 | 6.25e-01 | 91.9% | 66.7% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.82 | 73.0 | 4.86e-01 | 95.2% | 72.4% |
| 3vkgB03 | 1.20.58.1120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 | 0.82 | 73.0 | 5.31e-01 | 95.2% | 43.6% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.82 | 71.0 | 6.11e-01 | 91.9% | 74.7% |
| 2oh3A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.82 | 71.0 | 5.29e-01 | 93.5% | 45.8% |
| 1sg2A00 | 3.30.910.20 | Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain | 0.81 | 71.0 | 5.32e-01 | 93.5% | 43.3% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.81 | 73.0 | 6.24e-01 | 96.8% | 68.4% |
| 2e5yA02 | 1.20.5.440 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain | 0.81 | 56.0 | 6.40e-01 | 74.2% | 100.0% |
| 2cazC00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.80 | 63.0 | 6.26e-01 | 85.5% | 81.2% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 70.0 | 4.51e-01 | 95.2% | 35.6% |
| 8d3mA02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.80 | 67.0 | 4.38e-01 | 90.3% | 24.2% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.79 | 62.0 | 4.55e-01 | 85.5% | 46.0% |
| 4nwpD00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.79 | 69.0 | 5.05e-01 | 93.5% | 76.5% |
| 2hh7A00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.79 | 68.0 | 6.12e-01 | 95.2% | 75.3% |
| 4akgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.78 | 65.0 | 4.73e-01 | 91.9% | 54.8% |
| 2gw1A02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.77 | 61.0 | 3.67e-01 | 85.5% | 14.4% |
| 2c0gA02 | 1.20.1150.12 | Mainly Alpha › Up-down Bundle › Endoplasmic reticulum protein erp29 › Endoplasmic reticulum resident protein 29, C-terminal domain | 0.76 | 61.0 | 4.99e-01 | 85.5% | 84.0% |
| 2rd3D00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.75 | 65.0 | 4.39e-01 | 95.2% | 56.0% |
| 7k3zG01 | 3.50.7.10 | Alpha Beta › 3-Layer(bba) Sandwich › GroEL › GroEL | 0.75 | 62.0 | 4.14e-01 | 87.1% | 28.6% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.75 | 61.0 | 5.30e-01 | 87.1% | 63.3% |
| 1ni3A03 | 1.10.150.300 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain | 0.74 | 64.0 | 5.59e-01 | 93.5% | 64.8% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.74 | 52.0 | 4.69e-01 | 77.4% | 54.1% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.73 | 53.0 | 4.80e-01 | 79.0% | 56.3% |
| 5mmjn01 | 1.10.287.1480 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.73 | 49.0 | 4.36e-01 | 74.2% | 49.4% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 50.0 | 4.95e-01 | 74.2% | 98.5% |
| 4q5qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.72 | 58.0 | 4.92e-01 | 90.3% | 56.2% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.71 | 56.0 | 5.31e-01 | 91.9% | 73.0% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.71 | 58.0 | 4.70e-01 | 95.2% | 78.5% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 57.0 | 5.46e-01 | 88.7% | 83.3% |
| 3rm5B02 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.69 | 56.0 | 3.84e-01 | 91.9% | 53.6% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.68 | 54.0 | 4.40e-01 | 90.3% | 77.8% |
| 2wzkA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.64 | 51.0 | 4.18e-01 | 91.9% | 85.0% |
ECOD (81)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3480546 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.98 | 94.0 | 5.86e-01 | 100.0% | 23.4% |
| 57654 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.95 | 79.0 | 8.44e-01 | 88.7% | 100.0% |
| 1948638 | 4970.1.1.1 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.94 | 78.0 | 8.35e-01 | 88.7% | 100.0% |
| 3879987 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.94 | 67.0 | 6.62e-01 | 74.2% | 70.8% |
| 3976663 | 3812.1.1.1 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E | 0.92 | 78.0 | 7.65e-01 | 88.7% | 84.6% |
| 3249106 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.92 | 70.0 | 7.71e-01 | 80.6% | 98.0% |
| 3570403 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.91 | 76.0 | 5.82e-01 | 87.1% | 45.6% |
| 3932069 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.91 | 72.0 | 6.64e-01 | 82.3% | 70.7% |
| 3763454 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.91 | 76.0 | 5.89e-01 | 87.1% | 46.7% |
| 4156333 | 109.4.1.206 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › YfiO | 0.91 | 76.0 | 5.54e-01 | 88.7% | 38.0% |
| 3480097 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.91 | 73.0 | 6.94e-01 | 83.9% | 75.7% |
| 3504474 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.91 | 75.0 | 6.23e-01 | 87.1% | 56.0% |
| 3255948 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.90 | 73.0 | 5.73e-01 | 85.5% | 45.0% |
| 4272021 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.90 | 79.0 | 6.53e-01 | 91.9% | 87.0% |
| 3766400 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.90 | 75.0 | 6.01e-01 | 87.1% | 50.9% |
| 4971709 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.90 | 77.0 | 5.61e-01 | 88.7% | 39.3% |
| 3605450 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.90 | 75.0 | 4.51e-01 | 87.1% | 16.3% |
| 3884649 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.90 | 75.0 | 6.34e-01 | 87.1% | 58.9% |
| 3484694 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.90 | 74.0 | 4.46e-01 | 85.5% | 17.0% |
| 3965569 | 150.1.1.183 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Transposase_20 | 0.90 | 75.0 | 5.16e-01 | 87.1% | 31.7% |
| 3940953 | 109.4.1.623 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd1 | 0.90 | 75.0 | 4.13e-01 | 87.1% | 7.9% |
| 3617771 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.90 | 77.0 | 6.18e-01 | 90.3% | 77.3% |
| 3713604 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.90 | 76.0 | 4.64e-01 | 88.7% | 17.5% |
| 3498716 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.90 | 77.0 | 6.18e-01 | 90.3% | 63.6% |
| 3614078 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.90 | 75.0 | 5.79e-01 | 87.1% | 47.5% |
| 4955780 | 3939.1.1.387 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › DUF4349 | 0.90 | 74.0 | 7.33e-01 | 87.1% | 86.2% |
| 3550436 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.89 | 74.0 | 6.06e-01 | 87.1% | 67.3% |
| 3590755 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.89 | 76.0 | 7.77e-01 | 90.3% | 95.0% |
| 3492118 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.89 | 75.0 | 4.72e-01 | 87.1% | 21.5% |
| 3290879 | 3922.1.1.155 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF4349 | 0.89 | 74.0 | 7.06e-01 | 87.1% | 80.0% |
| 2810773 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.89 | 70.0 | 7.62e-01 | 87.1% | 100.0% |
| 3266812 | 3291.1.1.211 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › EMC3_TMCO1 | 0.89 | 75.0 | 5.35e-01 | 88.7% | 36.3% |
| 4979981 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.89 | 75.0 | 6.02e-01 | 88.7% | 80.0% |
| 3167235 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.89 | 77.0 | 5.46e-01 | 90.3% | 36.9% |
| 3417096 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.89 | 76.0 | 6.09e-01 | 90.3% | 53.6% |
| 3358885 | 604.12.1.8 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT | 0.89 | 70.0 | 6.39e-01 | 83.9% | 66.3% |
| 5048590 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.89 | 75.0 | 5.98e-01 | 88.7% | 78.2% |
| 5081365 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.88 | 77.0 | 5.64e-01 | 91.9% | 56.6% |
| 3247204 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.88 | 73.0 | 7.47e-01 | 87.1% | 90.0% |
| 3584462 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.88 | 78.0 | 5.22e-01 | 93.5% | 41.5% |
| 2814930 | 150.1.1.14 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › EncFtn-like | 0.88 | 73.0 | 6.51e-01 | 87.1% | 67.5% |
| 3969159 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.88 | 71.0 | 4.91e-01 | 85.5% | 28.6% |
| 3627942 | 3755.4.1.1 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 | 0.88 | 73.0 | 5.09e-01 | 87.1% | 32.6% |
| 3996264 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.88 | 73.0 | 5.12e-01 | 87.1% | 33.5% |
| 2394365 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.88 | 74.0 | 6.75e-01 | 88.7% | 89.7% |
| 3922888 | 109.4.1.889 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_M | 0.88 | 79.0 | 5.29e-01 | 95.2% | 42.4% |
| 4041347 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.88 | 75.0 | 5.95e-01 | 88.7% | 80.0% |
| 4576287 | 3755.3.1.471 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Paralemmin | 0.88 | 74.0 | 5.34e-01 | 88.7% | 36.8% |
| 3864054 | 192.10.1.0 ↗ | alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain | 0.88 | 73.0 | 5.66e-01 | 88.7% | 68.0% |
| 3369775 | 5076.2.1.10 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 | 0.88 | 73.0 | 4.60e-01 | 88.7% | 20.0% |
| 3638713 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.87 | 76.0 | 4.36e-01 | 91.9% | 57.6% |
| 3394272 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.87 | 76.0 | 5.32e-01 | 91.9% | 49.1% |
| 4551916 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.87 | 76.0 | 5.83e-01 | 91.9% | 48.0% |
| 3692897 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.87 | 73.0 | 6.79e-01 | 88.7% | 76.0% |
| 3600065 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.87 | 74.0 | 4.31e-01 | 90.3% | 31.7% |
| 3601402 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.86 | 75.0 | 4.58e-01 | 91.9% | 40.9% |
| 4531598 | 4970.1.1.14 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › RRP36 | 0.86 | 72.0 | 5.24e-01 | 88.7% | 52.3% |
| 4446039 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.86 | 71.0 | 6.79e-01 | 87.1% | 78.6% |
| 3925849 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.86 | 75.0 | 4.97e-01 | 91.9% | 71.6% |
| 3595966 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.86 | 71.0 | 6.84e-01 | 87.1% | 80.9% |
| 4115372 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.86 | 75.0 | 5.99e-01 | 91.9% | 78.2% |
| 3497029 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.86 | 75.0 | 6.21e-01 | 91.9% | 60.0% |
| 3699638 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.85 | 73.0 | 4.09e-01 | 91.9% | 20.2% |
| 3414767 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.85 | 71.0 | 6.44e-01 | 88.7% | 71.2% |
| 4419515 | 150.1.1.59 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F | 0.85 | 69.0 | 6.31e-01 | 87.1% | 71.2% |
| 3219646 | 3826.1.1.0 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) | 0.85 | 66.0 | 6.98e-01 | 83.9% | 98.2% |
| 3497934 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.84 | 73.0 | 4.69e-01 | 91.9% | 64.8% |
| 3273491 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.84 | 76.0 | 4.61e-01 | 95.2% | 25.6% |
| 3640083 | 2004.1.1.185 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11,AAA_12 | 0.84 | 71.0 | 4.28e-01 | 88.7% | 21.7% |
| 3302917 | 2004.1.1.505 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11, AAA_30 | 0.84 | 71.0 | 4.31e-01 | 88.7% | 23.3% |
| 3690329 | 2004.1.1.473 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII, AAA_11 | 0.84 | 70.0 | 4.22e-01 | 88.7% | 20.8% |
| 3224742 | 3755.3.1.9 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › SH3BP5 | 0.84 | 68.0 | 4.58e-01 | 87.1% | 26.5% |
| 3717958 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.84 | 76.0 | 4.24e-01 | 96.8% | 20.0% |
| 3820373 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.84 | 74.0 | 6.41e-01 | 93.5% | 64.4% |
| 4954852 | 101.1.2.136 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_20 | 0.84 | 68.0 | 4.76e-01 | 85.5% | 31.8% |
| 5016885 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.83 | 71.0 | 7.00e-01 | 91.9% | 84.6% |
| 3724988 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.83 | 70.0 | 4.18e-01 | 88.7% | 20.5% |
| 4170989 | 150.1.1.59 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F | 0.83 | 73.0 | 5.33e-01 | 93.5% | 74.7% |
| 5053066 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.82 | 72.0 | 4.73e-01 | 95.2% | 49.8% |
| 3385229 | 2003.1.9.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF | 0.82 | 65.0 | 3.90e-01 | 83.9% | 40.0% |
| 3599922 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.78 | 71.0 | 4.37e-01 | 100.0% | 40.9% |
D5
medium
residues 842-1021
Domain cluster:
rep: DNA_polymerase_catalytic_subunit__NP_073324__Meleagrid_alphaherpesvirus_1__37108__D926-999_1042-1063_1105-1149
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 142.4 | 2.80e-41 | 92.2% | 33.3% |