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DNA_gyrase_subunit_B

Euk-Vir

Kaumoebavirus_Viruses.

DNA_gyrase_subunit_B__YP_009352802__Kaumoebavirus_Viruses.__X

Identity

Accession:
YP_009352802 ↗
Protein ID:
DNA_gyrase_subunit_B
Kingdom:
euk

Quality

78.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 311-415
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qzrA02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.84 71.0 6.71e-01 96.2% 75.6%
3lnuA02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.75 69.0 5.91e-01 100.0% 67.1%
4hy1A02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.73 65.0 5.64e-01 99.0% 64.6%
3zkbI02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.72 66.0 5.70e-01 100.0% 66.3%
3iieB03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.62 42.0 4.56e-01 88.6% 85.9%
3mekA02 6.10.140.2220 Special › Helix non-globular › Helix Hairpins › 0.56 26.0 3.37e-01 93.3% 85.7%
2kzcA00 1.10.790.20 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Domain of unknown function DUF1476 0.54 31.0 3.40e-01 84.8% 68.2%
1h19A02 3.30.2010.30 Alpha Beta › 2-Layer Sandwich › Zincin-like › 0.51 37.0 3.90e-01 90.5% 85.6%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4000834 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.85 80.0 6.72e-01 100.0% 65.5%
3275256 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.85 79.0 6.58e-01 100.0% 61.2%
3799215 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.83 77.0 6.54e-01 100.0% 63.6%
3513708 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.83 77.0 6.60e-01 100.0% 68.1%
3220683 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.83 77.0 6.52e-01 100.0% 69.1%
3585145 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.83 77.0 6.58e-01 100.0% 66.3%
3433616 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.81 71.0 6.11e-01 97.1% 61.3%
4261801 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.78 71.0 5.80e-01 100.0% 58.4%
4234522 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.77 70.0 5.98e-01 100.0% 67.1%
3970715 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.77 70.0 5.86e-01 100.0% 63.4%
4641709 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.77 71.0 5.85e-01 100.0% 60.0%
3964340 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.77 70.0 5.76e-01 100.0% 59.5%
4298571 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.76 70.0 5.74e-01 100.0% 61.6%
3807571 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.76 69.0 5.82e-01 100.0% 63.4%
4380841 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.76 69.0 5.83e-01 100.0% 64.0%
4207771 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.76 69.0 5.83e-01 100.0% 62.9%
4040519 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.76 62.0 5.31e-01 93.3% 55.8%
3967155 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.75 69.0 5.77e-01 100.0% 62.9%
4027043 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.75 68.0 5.73e-01 100.0% 62.9%
4945732 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.75 68.0 5.72e-01 100.0% 65.1%
4288775 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.74 67.0 5.57e-01 100.0% 60.6%
1388837 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.72 60.0 5.33e-01 93.3% 63.7%
3594648 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.70 64.0 5.52e-01 100.0% 68.8%
4237384 171.1.1.4 ↗ alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonucleas_3_3 0.52 45.0 4.06e-01 96.2% 84.8%
D2 high residues 437-586_649-728
PDB
Domain cluster: rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D385-517_553-621_640-664
D3 high residues 587-641
PDB
D4 high residues 923-1020
PDB
Domain cluster: rep: IMGVR_UViG_3300007985_000017-3300007985-Ga0100381_100027569__D212-299
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 32.9 4.90e-08 87.8% 17.4%
CATH (81)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8gccA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.92 76.0 8.08e-01 93.9% 97.7%
3qx3B03 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.87 79.0 7.87e-01 100.0% 93.0%
3l4jA04 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.84 77.0 7.63e-01 100.0% 93.1%
3lpxB02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.81 69.0 7.06e-01 94.9% 93.6%
6bq9A02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.76 64.0 6.60e-01 94.9% 93.6%
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 49.0 5.52e-01 82.7% 93.2%
3ewgA00 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.69 45.0 4.90e-01 77.6% 80.0%
1b24A01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.69 52.0 5.31e-01 79.6% 90.5%
2cdqA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 52.0 5.59e-01 91.8% 95.2%
4pcqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.68 46.0 4.93e-01 79.6% 81.0%
7qh2C03 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 50.0 5.52e-01 81.6% 97.4%
2m9kA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.68 46.0 4.70e-01 82.7% 73.1%
2dchX01 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.67 45.0 4.64e-01 80.6% 72.0%
2xhcA01 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.67 44.0 4.49e-01 78.6% 68.4%
2l48A00 3.30.70.2030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 43.0 4.54e-01 81.6% 74.1%
1m1hA01 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.67 46.0 4.59e-01 79.6% 69.0%
5w2fA01 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.66 49.0 5.15e-01 88.8% 87.2%
2dt9A01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 48.0 5.32e-01 89.8% 100.0%
1itpA00 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.66 42.0 4.58e-01 82.7% 80.5%
2j0wA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 49.0 5.31e-01 89.8% 95.1%
2go8A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 43.0 4.83e-01 78.6% 87.8%
5zneA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 42.0 4.72e-01 80.6% 87.7%
1a9nD00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.65 47.0 4.85e-01 83.7% 80.6%
2kkhA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 44.0 4.88e-01 80.6% 90.7%
2p5vA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.65 44.0 4.67e-01 79.6% 81.0%
1i6uA01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.65 43.0 5.04e-01 78.6% 98.5%
6j6ga00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.65 45.0 4.75e-01 79.6% 83.3%
1qupA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 41.0 4.67e-01 79.6% 90.0%
2gqqA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.64 44.0 4.67e-01 79.6% 81.2%
2dbbA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.64 43.0 4.47e-01 80.6% 73.1%
2kjwA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.64 46.0 4.66e-01 81.6% 76.0%
2pd1A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 47.0 4.83e-01 81.6% 81.1%
2b4vA03 3.30.70.1970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 46.0 4.59e-01 83.7% 73.7%
6gmhK00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.63 48.0 4.62e-01 94.9% 69.6%
6u26A01 3.30.70.80 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptidase S8 propeptide/proteinase inhibitor I9 0.63 48.0 5.01e-01 96.9% 89.8%
4u9rA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 48.0 5.15e-01 81.6% 97.6%
2dgxA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.63 46.0 4.95e-01 80.6% 93.8%
3kg0A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 48.0 4.85e-01 81.6% 83.5%
1y4uB01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.63 53.0 4.18e-01 90.8% 74.7%
1dq3A04 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.62 47.0 4.51e-01 83.7% 69.3%
4p6qA02 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 43.0 4.74e-01 81.6% 92.1%
4d9uA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.62 41.0 4.33e-01 75.5% 75.0%
3gz7B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 47.0 4.77e-01 81.6% 84.7%
1hl6C00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 45.0 4.36e-01 82.7% 67.6%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 47.0 4.74e-01 79.6% 82.3%
3tviA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.62 51.0 4.36e-01 89.8% 95.0%
2c2nA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.62 41.0 4.50e-01 80.6% 85.7%
7csxA02 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 42.0 4.72e-01 80.6% 95.8%
1y0hB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 47.0 4.71e-01 81.6% 81.6%
4dpoB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 47.0 4.66e-01 81.6% 80.2%
4g08A02 3.30.1370.120 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.60 40.0 4.57e-01 81.6% 95.7%
3znuA00 3.30.70.1060 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel 0.60 44.0 4.49e-01 80.6% 80.9%
2q7eA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.60 42.0 3.31e-01 74.5% 52.8%
1tuwA00 3.30.70.1090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. 0.60 45.0 4.44e-01 80.6% 75.5%
3s6eB00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.60 45.0 4.38e-01 84.7% 71.2%
4dn9B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 44.0 4.46e-01 81.6% 80.4%
1iujA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 45.0 4.47e-01 81.6% 81.4%
2jvfA00 3.30.1710.10 Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein 0.59 40.0 4.11e-01 70.4% 100.0%
5mmjh01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.59 43.0 4.79e-01 77.6% 100.0%
1x5oA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 44.0 4.65e-01 80.6% 94.2%
2psoB02 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.58 47.0 3.91e-01 88.8% 95.5%
2clqA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 38.0 4.03e-01 73.5% 78.8%
1in0A02 3.30.70.990 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YajQ-like, domain 2 0.56 39.0 4.05e-01 72.4% 84.8%
3c1mA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.56 50.0 4.20e-01 100.0% 100.0%
1i94H01 3.30.1370.30 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › 0.55 41.0 4.47e-01 77.6% 100.0%
3elkA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 40.0 3.99e-01 77.6% 78.1%
6abqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.55 40.0 3.94e-01 76.5% 78.3%
2p92A00 3.30.70.1490 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp 0.54 43.0 4.36e-01 100.0% 89.5%
4g6tA00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.54 44.0 4.12e-01 98.0% 71.1%
2qrrA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.54 41.0 4.14e-01 82.7% 83.5%
1x19A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 37.0 3.17e-01 71.4% 85.6%
2uvaG03 3.30.70.3320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 42.0 4.12e-01 86.7% 77.8%
4r9iA02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.53 29.0 2.89e-01 81.6% 48.0%
1ie0A00 3.30.1360.80 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › S-ribosylhomocysteinase (LuxS) 0.53 46.0 4.05e-01 100.0% 85.9%
5dymA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 39.0 3.93e-01 76.5% 83.3%
4o1pD02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.53 46.0 3.51e-01 99.0% 53.6%
3l7wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 42.0 4.18e-01 86.7% 86.7%
1s28A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.53 42.0 3.87e-01 88.8% 67.7%
4gf3A00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.52 42.0 3.95e-01 100.0% 71.5%
1s9iB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 37.0 3.77e-01 78.6% 77.4%
2kx2A00 3.30.780.30 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › 0.51 43.0 4.40e-01 93.9% 97.9%
ECOD (93)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3096551 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 89.0 6.95e-01 100.0% 54.1%
3614277 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.90 78.0 6.18e-01 100.0% 49.4%
3719735 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.89 80.0 6.51e-01 100.0% 55.8%
3594650 4014.1.1.0 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.89 77.0 6.38e-01 100.0% 55.6%
2390536 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 76.0 6.29e-01 96.9% 55.6%
3277529 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.87 78.0 6.42e-01 100.0% 57.5%
3188905 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.84 80.0 6.31e-01 100.0% 55.0%
3789606 4014.1.1.0 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.80 75.0 6.10e-01 100.0% 57.1%
3998667 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.80 76.0 5.88e-01 100.0% 51.8%
4887990 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.80 70.0 5.84e-01 100.0% 57.1%
3220665 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.79 74.0 5.97e-01 100.0% 57.7%
4878007 101.1.2.9 ↗ alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.78 69.0 6.00e-01 98.0% 64.8%
4855517 101.1.2.9 ↗ alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.77 73.0 5.40e-01 100.0% 47.8%
4266765 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.77 71.0 5.83e-01 100.0% 58.2%
3590557 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.76 71.0 5.56e-01 100.0% 54.9%
4624017 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.76 71.0 5.70e-01 100.0% 57.2%
2140592 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.74 69.0 5.49e-01 100.0% 57.7%
3250936 304.15.1.0 ↗ a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain 0.74 47.0 5.49e-01 75.5% 91.4%
3252800 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.72 47.0 5.59e-01 75.5% 98.5%
3269235 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.71 47.0 5.47e-01 77.6% 94.3%
3268586 306.3.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.71 51.0 5.12e-01 90.8% 74.0%
5036213 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.70 49.0 5.07e-01 80.6% 77.8%
4943756 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.70 46.0 4.34e-01 81.6% 55.0%
3290652 306.2.1.0 ↗ a+b two layers › Glucose permease domain IIB-like › arginine repressor C terminal domain-related › C-terminal domain of arginine repressor 0.70 53.0 5.55e-01 90.8% 87.8%
4937376 304.17.1.2 ↗ a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN 0.70 45.0 4.90e-01 78.6% 80.0%
4944621 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.69 46.0 4.25e-01 80.6% 52.8%
4945096 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.69 46.0 4.57e-01 81.6% 63.8%
4519566 4955.1.1.0 ↗ a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.69 52.0 5.70e-01 90.8% 98.8%
1211839 242.1.1.7 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.68 50.0 5.10e-01 77.6% 87.5%
4937799 4956.1.1.0 ↗ a+b two layers › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.67 43.0 4.90e-01 78.6% 90.0%
4020561 306.3.1.0 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.67 51.0 5.06e-01 100.0% 78.0%
4930463 304.17.1.2 ↗ a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN 0.67 44.0 4.60e-01 79.6% 73.3%
5031028 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.66 45.0 4.36e-01 81.6% 61.8%
3738706 320.1.1.0 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain 0.65 46.0 4.28e-01 72.4% 62.5%
3829402 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 50.0 5.35e-01 88.8% 100.0%
4204243 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.65 47.0 3.03e-01 83.7% 16.4%
3651874 306.3.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.65 50.0 5.01e-01 100.0% 80.0%
3843541 306.3.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.65 49.0 4.78e-01 90.8% 71.8%
3596068 306.3.1.0 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.65 50.0 5.19e-01 100.0% 88.9%
3998431 306.3.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.64 49.0 4.77e-01 90.8% 71.8%
4518165 207.11.1.1 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.64 57.0 4.13e-01 99.0% 90.4%
3345154 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.64 42.0 4.61e-01 80.6% 84.6%
3611985 304.3.1.1 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.64 42.0 4.55e-01 81.6% 82.5%
4343880 304.28.1.2 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Sec_GG 0.64 45.0 4.77e-01 83.7% 85.9%
5025432 304.165.1.0 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 0.64 49.0 4.14e-01 82.7% 81.8%
3500307 306.3.1.0 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like 0.64 48.0 4.55e-01 90.8% 67.8%
4378578 304.11.1.2 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › SAT 0.63 41.0 4.66e-01 85.7% 91.4%
4026919 306.3.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.63 48.0 4.69e-01 90.8% 71.8%
3517813 306.3.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.63 49.0 5.18e-01 100.0% 92.0%
5009401 304.165.1.0 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 0.63 50.0 4.48e-01 84.7% 94.1%
3317802 304.8.1.45 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.63 52.0 5.32e-01 89.8% 95.8%
3591340 206.1.1.10 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Choline_kinase 0.63 53.0 3.39e-01 91.8% 82.0%
5075416 242.1.1.7 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.63 47.0 4.53e-01 78.6% 88.2%
4311880 304.11.1.4 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › FAS_AT_central 0.62 42.0 4.11e-01 86.7% 63.8%
3602142 242.1.1.7 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.62 45.0 4.40e-01 80.6% 70.5%
3312923 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 51.0 5.20e-01 90.8% 95.8%
5052854 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 47.0 4.17e-01 82.7% 86.8%
3643150 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 49.0 5.15e-01 100.0% 100.0%
3300216 306.3.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.61 46.0 4.50e-01 90.8% 74.3%
2595266 241.1.1.6 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › YbjN 0.61 50.0 4.52e-01 89.8% 72.6%
5001154 206.1.1.9 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 0.61 55.0 4.48e-01 99.0% 70.6%
5029357 242.1.1.7 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.61 45.0 4.27e-01 83.7% 66.1%
4529236 207.11.1.1 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.61 53.0 3.92e-01 99.0% 92.6%
1954213 241.1.1.6 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › YbjN 0.61 49.0 4.38e-01 89.8% 67.6%
3588048 304.156.1.0 ↗ a+b two layers › Alpha-beta plaits › DNA translocase FtsK N-terminal domain › DNA translocase FtsK N-terminal domain 0.61 42.0 4.12e-01 71.4% 81.9%
1442273 304.11.1.4 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › FAS_AT_central 0.61 41.0 4.18e-01 86.7% 71.1%
4946187 241.6.1.0 ↗ a+b two layers › Type III secretory system chaperone-like › Arp2/3 complex subunits › Arp2/3 complex subunits 0.60 47.0 4.42e-01 88.8% 67.2%
3507255 304.11.1.0 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.60 38.0 4.29e-01 77.6% 84.0%
3178984 206.1.1.11 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.59 53.0 3.86e-01 100.0% 84.3%
3450309 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.59 50.0 5.15e-01 96.9% 97.9%
4172447 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 42.0 4.72e-01 76.5% 98.7%
4505080 242.1.1.2 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 0.59 45.0 4.20e-01 82.7% 73.6%
3433011 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.59 44.0 4.12e-01 81.6% 65.0%
5018607 304.128.1.0 ↗ a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB 0.58 44.0 4.60e-01 82.7% 87.8%
4237289 207.11.1.1 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD 0.58 51.0 3.78e-01 99.0% 93.5%
4373762 242.1.1.2 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 0.57 44.0 4.19e-01 83.7% 76.7%
2583503 304.156.1.0 ↗ a+b two layers › Alpha-beta plaits › DNA translocase FtsK N-terminal domain › DNA translocase FtsK N-terminal domain 0.57 41.0 4.26e-01 74.5% 100.0%
3272845 206.1.1.70 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.57 51.0 3.45e-01 100.0% 47.6%
3831694 5104.1.1.1 ↗ a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.57 50.0 4.52e-01 100.0% 86.2%
4997572 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.56 44.0 4.34e-01 90.8% 78.2%
3709408 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.56 50.0 3.56e-01 100.0% 60.2%
5000362 306.3.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.56 44.0 4.50e-01 87.8% 96.8%
5083337 101.1.2.14 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.56 38.0 3.91e-01 75.5% 72.6%
3614406 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.56 49.0 3.55e-01 100.0% 60.2%
3964731 304.3.1.1 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA 0.56 48.0 4.77e-01 95.9% 94.0%
4126668 304.11.1.0 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.55 43.0 4.21e-01 85.7% 78.1%
3689719 206.1.1.11 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.55 48.0 3.48e-01 100.0% 87.8%
3675646 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.54 45.0 3.37e-01 91.8% 47.5%
2531310 306.3.1.1 ↗ a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 0.54 44.0 4.18e-01 91.8% 84.7%
4934055 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.53 37.0 3.97e-01 71.4% 92.5%
3724718 206.1.1.11 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.53 47.0 3.38e-01 100.0% 78.3%
4928473 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.52 45.0 3.36e-01 99.0% 39.6%
3184022 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.51 40.0 3.72e-01 86.7% 90.8%
D5 high residues 1046-1171
PDB
Domain cluster: rep: hypothetical_protein_MIV086L__YP_654658__Invertebrate_iridescent_virus_3__345201__D990-1107
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.84 44.0 5.09e-01 93.7% 69.5%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.82 38.0 4.15e-01 100.0% 52.3%
8gccA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.81 64.0 7.10e-01 95.2% 100.0%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.79 33.0 4.25e-01 88.9% 66.2%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.79 42.0 5.36e-01 96.0% 88.0%
3qx3A04 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.78 60.0 6.68e-01 88.9% 100.0%
1bgwA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.75 62.0 6.65e-01 89.7% 99.1%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.74 48.0 4.05e-01 100.0% 42.1%
1zvuA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.72 56.0 5.46e-01 100.0% 74.3%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 47.0 4.59e-01 100.0% 62.6%
1qbzA00 1.10.287.210 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 46.0 5.05e-01 100.0% 82.4%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 48.0 3.80e-01 100.0% 38.6%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 47.0 5.05e-01 71.4% 83.2%
3lpxA03 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.63 48.0 5.31e-01 87.3% 97.1%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.62 43.0 3.79e-01 100.0% 48.9%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 43.0 3.86e-01 99.2% 52.0%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 50.0 4.83e-01 92.1% 81.1%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.57 51.0 5.14e-01 92.9% 96.8%
2rfqC03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 41.0 3.65e-01 73.0% 65.7%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.57 47.0 4.79e-01 96.0% 90.4%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.56 41.0 4.54e-01 96.0% 95.0%
1aluA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 45.0 4.15e-01 92.9% 67.5%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 38.0 3.64e-01 71.4% 66.4%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.55 50.0 4.89e-01 100.0% 100.0%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.53 43.0 4.42e-01 87.3% 100.0%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 39.0 3.41e-01 79.4% 78.4%
3dyjA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.51 43.0 3.98e-01 93.7% 81.3%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.51 42.0 3.59e-01 92.1% 61.3%
1r8iA00 1.20.58.430 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Type IV secretion system, VirB5-domain 0.50 46.0 4.05e-01 100.0% 71.7%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.50 36.0 4.00e-01 74.6% 95.1%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3662019 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.88 46.0 4.41e-01 100.0% 45.5%
3600354 4016.1.1.0 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.86 69.0 6.46e-01 100.0% 69.3%
3708939 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.86 69.0 6.37e-01 100.0% 67.1%
3935542 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.84 70.0 6.54e-01 100.0% 72.7%
3096549 4016.1.1.0 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.83 77.0 6.93e-01 100.0% 74.7%
3652359 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.82 69.0 6.16e-01 100.0% 64.7%
3509307 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.81 47.0 4.18e-01 99.2% 42.3%
3789604 4016.1.1.0 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.81 72.0 6.75e-01 100.0% 78.0%
4887991 4016.1.1.0 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase 0.81 58.0 6.27e-01 92.1% 86.0%
223696 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.80 71.0 6.61e-01 100.0% 77.5%
3267708 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.79 67.0 6.36e-01 100.0% 76.6%
3849009 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.79 44.0 3.35e-01 100.0% 26.5%
3610015 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.79 71.0 6.40e-01 100.0% 72.1%
3630114 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.79 70.0 6.60e-01 100.0% 80.7%
3276180 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.77 73.0 6.17e-01 100.0% 75.4%
3488292 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.77 41.0 4.36e-01 93.7% 60.0%
3718739 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.76 72.0 6.51e-01 100.0% 76.4%
1297277 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.75 59.0 5.20e-01 100.0% 57.5%
3857880 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 44.0 4.24e-01 100.0% 51.0%
4025638 1189.1.1.0 ↗ alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.75 43.0 3.68e-01 100.0% 36.9%
4238706 101.1.2.9 ↗ alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.75 71.0 5.17e-01 100.0% 44.9%
3768919 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.74 71.0 5.18e-01 100.0% 46.3%
3634044 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.74 71.0 6.02e-01 100.0% 72.1%
3508111 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.74 70.0 6.11e-01 100.0% 80.0%
4452951 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.74 70.0 6.15e-01 100.0% 74.3%
3328306 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.74 70.0 5.98e-01 100.0% 73.2%
3201856 2004.1.1.199 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B 0.71 45.0 2.87e-01 81.0% 14.0%
3692753 5086.1.1.12 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Uds1 0.71 42.0 3.92e-01 100.0% 48.7%
2443871 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.71 67.0 6.04e-01 100.0% 77.1%
3696555 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.70 50.0 4.31e-01 72.2% 80.0%
5015079 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.69 44.0 2.99e-01 100.0% 18.0%
4018811 603.1.1.158 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › KAR9 0.69 37.0 3.66e-01 100.0% 48.5%
3244448 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 46.0 4.21e-01 100.0% 56.9%
3542202 3755.3.1.44 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › JMY 0.65 45.0 4.03e-01 100.0% 53.9%
3686025 604.7.1.10 ↗ alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › Tmemb_170 0.64 38.0 3.52e-01 92.9% 47.7%
3553221 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.61 42.0 4.29e-01 71.4% 73.3%
5062336 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.60 54.0 4.95e-01 100.0% 87.9%
4596972 150.3.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.59 55.0 4.66e-01 98.4% 99.5%
4211798 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.59 41.0 3.63e-01 100.0% 50.0%
4964968 192.2.1.88 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › NFACT_N 0.57 53.0 4.86e-01 100.0% 82.5%
4088407 150.3.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.56 52.0 4.44e-01 100.0% 99.0%
3239790 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 41.0 4.28e-01 100.0% 82.6%
5031247 3755.3.1.127 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NFACT_N 0.55 50.0 4.55e-01 100.0% 80.0%
5045441 192.2.1.88 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › NFACT_N 0.55 50.0 4.54e-01 100.0% 81.8%
3447988 603.1.1.102 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF3537 0.54 42.0 3.64e-01 81.0% 75.9%
3786466 601.1.2.75 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PTPLA 0.54 45.0 3.76e-01 88.9% 59.1%
3477269 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.54 43.0 3.98e-01 100.0% 67.1%
3546316 3922.1.1.186 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › WWC1 0.54 44.0 3.84e-01 100.0% 58.4%
3855780 604.1.1.66 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL 0.54 39.0 4.14e-01 75.4% 88.7%
3452483 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 49.0 4.33e-01 100.0% 75.1%
4994917 3834.1.1.25 ↗ alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 0.54 45.0 3.57e-01 100.0% 45.7%
3994861 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 44.0 3.99e-01 88.1% 72.4%
4340169 601.3.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.53 42.0 4.27e-01 91.3% 85.4%
5065305 601.14.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.53 45.0 4.10e-01 94.4% 80.0%
4310744 563.1.1.1 ↗ alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.53 43.0 4.01e-01 88.1% 75.0%
3595538 3711.1.1.0 ↗ alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.52 40.0 3.81e-01 98.4% 69.0%
4012828 196.1.1.0 ↗ alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS 0.52 45.0 3.91e-01 92.1% 64.3%
4947883 5082.1.1.6 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › ZT_dimer 0.51 46.0 3.92e-01 98.4% 69.0%
D6 medium residues 60-74_100-130_143-214
PDB
Domain cluster: rep: GyrB-like_ATPase_domain_protein__YP_784274__Nile_crocodilepox_virus__1285600__D74-178
D7 medium residues 75-99_215-277
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1jndA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.64 48.0 3.31e-01 80.7% 44.4%
3w4rA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.63 47.0 3.28e-01 80.7% 43.3%
1bifA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 45.0 3.44e-01 76.1% 82.0%
3inpA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.59 44.0 3.32e-01 79.5% 43.6%
2rh8A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 43.0 2.95e-01 77.3% 59.6%
4loaA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 43.0 3.56e-01 80.7% 71.5%
2ajtA01 3.40.50.10940 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.54 40.0 3.25e-01 79.5% 95.4%
4maaA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 38.0 3.12e-01 80.7% 51.2%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4969716 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.69 48.0 3.62e-01 71.6% 89.0%
3704849 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.63 50.0 3.53e-01 84.1% 90.9%
3679568 207.1.1.95 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_14 0.61 42.0 2.63e-01 70.5% 17.8%
3515781 7512.1.1.66 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Exostosin_GT47 0.56 49.0 3.91e-01 100.0% 58.4%
3483520 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.54 47.0 3.23e-01 98.9% 62.2%
3422461 207.1.1.95 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_14 0.53 47.0 3.22e-01 96.6% 30.3%
3680511 2484.1.1.26 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Piwi 0.53 39.0 2.97e-01 78.4% 62.0%