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DNA_helicase,_transcritional_elongation
Euk-VirSheeppox_virus
DNA_helicase,_transcritional_elongation__NP_659682__Sheeppox_virus__10266
Identity
- Accession:
- NP_659682 ↗
- Protein ID:
- DNA_helicase,_transcritional_elongation
- Kingdom:
- euk
Quality
87.4
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Capripoxvirus›
Sheeppox_virus
TaxID: 10266
Cluster
View cluster (178 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 270-457
Domain cluster:
rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00271.38 best | Helicase_C | 29.3 | 1.20e-06 | 61.2% | 89.1% |
D2
medium
residues 1-52
Domain cluster:
rep: 110R__NP_938365__Yaba_monkey_tumor_virus__38804__D1-54
D3
medium
residues 105-144_205-254
Domain cluster:
rep: hypothetical_protein_VARVgp122__NP_042166__Variola_virus__10255__D95-132_210-254
D4
medium
residues 145-204
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vecA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.73 | 63.0 | 4.40e-01 | 100.0% | 32.5% |
| 3berA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.71 | 61.0 | 4.21e-01 | 100.0% | 30.5% |
| 3cfyA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.70 | 60.0 | 4.74e-01 | 100.0% | 65.4% |
| 3jteA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.68 | 58.0 | 4.67e-01 | 100.0% | 69.8% |
| 6lpiD03 | 3.40.50.970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | 0.65 | 54.0 | 4.08e-01 | 100.0% | 97.6% |
| 3votA01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.65 | 54.0 | 4.63e-01 | 96.7% | 83.2% |
| 3tc3B00 | 3.20.20.150 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes | 0.64 | 54.0 | 3.53e-01 | 100.0% | 71.4% |
| 1dekA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 52.0 | 4.27e-01 | 100.0% | 48.3% |
| 3okpA01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.61 | 51.0 | 3.74e-01 | 100.0% | 63.0% |
| 4kp7A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.61 | 52.0 | 3.87e-01 | 96.7% | 52.3% |
| 1zccA00 | 3.20.20.190 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphatidylinositol (PI) phosphodiesterase | 0.61 | 50.0 | 3.47e-01 | 100.0% | 89.2% |
| 5lomA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.60 | 47.0 | 4.27e-01 | 100.0% | 61.5% |
| 1j1uA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.60 | 50.0 | 3.62e-01 | 100.0% | 73.0% |
| 4xrpA02 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.60 | 49.0 | 4.00e-01 | 100.0% | 73.6% |
| 2d00A01 | 3.40.50.10580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ATPase, V1 complex, subunit F | 0.59 | 43.0 | 4.22e-01 | 81.7% | 79.1% |
| 1vddA03 | 3.40.1360.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › | 0.59 | 47.0 | 4.30e-01 | 98.3% | 82.6% |
| 5w16A02 | 3.40.50.1860 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.59 | 50.0 | 4.29e-01 | 100.0% | 97.1% |
| 3delB02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.58 | 45.0 | 4.06e-01 | 100.0% | 59.1% |
| 1wdnA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.58 | 45.0 | 4.04e-01 | 93.3% | 79.2% |
| 3vv5A02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.58 | 47.0 | 4.15e-01 | 100.0% | 59.2% |
| 4i62A02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.57 | 47.0 | 4.19e-01 | 100.0% | 63.4% |
| 1egaA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 46.0 | 3.47e-01 | 100.0% | 72.4% |
| 8g0cG01 | 3.40.1380.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › ATP synthase, F1 complex, gamma subunit | 0.57 | 46.0 | 3.20e-01 | 90.0% | 33.6% |
| 1mzhA00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.55 | 45.0 | 3.24e-01 | 100.0% | 65.8% |
| 8dbsG01 | 3.40.1380.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › ATP synthase, F1 complex, gamma subunit | 0.55 | 42.0 | 3.01e-01 | 90.0% | 32.6% |
| 3kbrA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.55 | 42.0 | 3.84e-01 | 98.3% | 60.4% |
| 2r7kA01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.55 | 43.0 | 3.67e-01 | 96.7% | 50.5% |
| 2pvuA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 44.0 | 3.88e-01 | 100.0% | 60.2% |
| 4uhwA03 | 3.30.43.10 | Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2 › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2 | 0.53 | 36.0 | 3.55e-01 | 71.7% | 88.1% |
| 1iuqA02 | 3.40.1130.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase | 0.52 | 39.0 | 2.66e-01 | 86.7% | 21.7% |
| 2b4oA02 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.51 | 41.0 | 3.00e-01 | 100.0% | 51.6% |
| 3agkA03 | 3.30.1330.30 | Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Ribosomal protein L30/S12 | 0.51 | 40.0 | 3.69e-01 | 100.0% | 64.5% |
| 2pbzA01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.50 | 38.0 | 3.57e-01 | 90.0% | 91.5% |
ECOD (33)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3237175 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.80 | 70.0 | 4.69e-01 | 100.0% | 30.9% |
| 3088345 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.79 | 65.0 | 4.73e-01 | 100.0% | 33.5% |
| 3482521 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.77 | 68.0 | 4.44e-01 | 100.0% | 30.2% |
| 5022252 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.75 | 67.0 | 4.58e-01 | 100.0% | 30.7% |
| 4153562 | 2004.1.1.23 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom | 0.74 | 64.0 | 4.26e-01 | 100.0% | 24.8% |
| 3597207 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.74 | 64.0 | 3.84e-01 | 100.0% | 15.8% |
| 3627729 | 2004.1.1.120 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII | 0.73 | 65.0 | 4.12e-01 | 100.0% | 23.0% |
| 4273731 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.73 | 64.0 | 4.17e-01 | 100.0% | 24.4% |
| 3576230 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.73 | 65.0 | 4.24e-01 | 100.0% | 27.5% |
| 3368345 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.72 | 61.0 | 4.16e-01 | 100.0% | 27.5% |
| 3268477 | 2004.1.1.364 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C | 0.71 | 60.0 | 3.54e-01 | 100.0% | 13.0% |
| 4682251 | 2007.1.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like | 0.70 | 61.0 | 3.68e-01 | 100.0% | 20.5% |
| 3781041 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.69 | 60.0 | 3.96e-01 | 100.0% | 29.6% |
| 3594482 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.68 | 58.0 | 3.99e-01 | 100.0% | 27.8% |
| 4972373 | 7589.1.1.1 ↗ | a/b three-layered sandwiches › YgbK-like › YgbK-like › YgbK-like › SBD_N | 0.68 | 60.0 | 3.99e-01 | 100.0% | 29.0% |
| 4205955 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.67 | 54.0 | 3.78e-01 | 100.0% | 27.5% |
| 3645791 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.67 | 55.0 | 4.45e-01 | 93.3% | 51.7% |
| 4271781 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.65 | 52.0 | 3.73e-01 | 100.0% | 28.9% |
| 4945305 | 213.1.1.0 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) | 0.64 | 52.0 | 4.73e-01 | 93.3% | 88.2% |
| 4385096 | 4978.1.1.1 ↗ | a/b three-layered sandwiches › a/b domain in AF0625-like proteins › a/b domain in AF0625-like proteins › a/b domain in AF0625-like proteins › tRNA_deacylase | 0.62 | 49.0 | 4.55e-01 | 96.7% | 81.2% |
| 3097431 | 282.1.1.1 ↗ | a+b duplicates or obligate multimers › CBS-domain › CBS-domain › CBS-domain › CBS | 0.60 | 34.0 | 3.10e-01 | 95.0% | 40.5% |
| 4634179 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.59 | 47.0 | 4.15e-01 | 100.0% | 58.0% |
| 4876649 | 1137.1.1.1 ↗ | a+b two layers › Tetrapyrrole methylase C-terminal domain-like › Tetrapyrrole methylase C-terminal domain › Tetrapyrrole methylase C-terminal domain › TP_methylase | 0.58 | 49.0 | 4.57e-01 | 100.0% | 86.3% |
| 3444269 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.58 | 47.0 | 4.02e-01 | 95.0% | 75.5% |
| 3957853 | 2006.1.1.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase | 0.58 | 46.0 | 4.14e-01 | 93.3% | 86.7% |
| 1523027 | 7523.1.1.0 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II | 0.58 | 47.0 | 4.25e-01 | 100.0% | 64.4% |
| 3953121 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.58 | 48.0 | 3.78e-01 | 100.0% | 57.9% |
| 3516781 | 2003.4.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP | 0.57 | 39.0 | 3.06e-01 | 96.7% | 32.3% |
| 4143164 | 7519.1.1.1 ↗ | a/b three-layered sandwiches › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › ATP synthase (F1-ATPase), gamma subunit › ATP-synt | 0.57 | 45.0 | 3.03e-01 | 90.0% | 24.9% |
| 4007520 | 7523.1.1.19 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › NMT1 | 0.55 | 45.0 | 4.03e-01 | 100.0% | 63.2% |
| 3566328 | 7512.1.1.46 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_11 | 0.55 | 41.0 | 3.47e-01 | 85.0% | 50.9% |
| 3505358 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.53 | 37.0 | 2.49e-01 | 76.7% | 16.4% |
| 3989984 | 2484.1.1.66 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 | 0.51 | 41.0 | 3.46e-01 | 98.3% | 82.4% |