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DNA_helicase-primase_complex_component

Euk-Vir

Eptesicus_fuscus_gammaherpesvirus

DNA_helicase-primase_complex_component__YP_009552507__Eptesicus_fuscus_gammaherpesvirus__2035399

Identity

Accession:
YP_009552507 ↗
Protein ID:
DNA_helicase-primase_complex_component
Kingdom:
euk

Quality

73.0 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Eptesicus_fuscus_gammaherpesvirus

TaxID: 2035399

Cluster

View cluster (90 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 168-209_391-414
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF02689.21 best Herpes_Helicase 75.5 3.70e-21 66.7% 5.3%
PF02689.21 Herpes_Helicase 42.4 3.60e-11 40.9% 3.3%
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8ouzD01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 55.0 3.70e-01 78.8% 80.8%
6b4kB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 48.0 3.60e-01 71.2% 92.9%
7l4aA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 55.0 3.92e-01 97.0% 79.5%
4xrpA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 55.0 4.36e-01 97.0% 96.4%
1zm7B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 56.0 4.00e-01 100.0% 85.9%
6qj2A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 45.0 2.81e-01 77.3% 88.2%
2gzaB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 46.0 3.28e-01 86.4% 70.4%
2oap202 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 44.0 2.98e-01 84.8% 51.6%
3u7eB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 49.0 3.64e-01 98.5% 65.2%
1lwdA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.57 41.0 2.59e-01 78.8% 42.6%
1lsuA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 40.0 3.27e-01 75.8% 88.1%
2cvzA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 38.0 2.99e-01 72.7% 74.4%
4mp8A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 38.0 2.93e-01 74.2% 57.2%
3s7zA01 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 39.0 3.20e-01 75.8% 67.7%
3phhA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 37.0 3.05e-01 71.2% 70.0%
4g65A03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 37.0 3.01e-01 71.2% 88.1%
3abiA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 38.0 2.86e-01 74.2% 68.0%
1ne2B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 40.0 3.03e-01 83.3% 86.9%
2qkbA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.54 40.0 3.19e-01 81.8% 98.0%
3r4vA01 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.54 46.0 3.07e-01 100.0% 44.0%
3kkjA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 40.0 3.16e-01 81.8% 88.2%
3d1lB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 39.0 3.00e-01 77.3% 72.7%
3iusB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 3.00e-01 95.5% 85.6%
1l9fA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 41.0 3.05e-01 84.8% 79.4%
3uj9A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 39.0 2.75e-01 83.3% 86.0%
1x7dA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 36.0 2.75e-01 71.2% 58.8%
6hrdA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 44.0 3.24e-01 95.5% 52.9%
8c0zE01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 37.0 3.02e-01 74.2% 75.6%
8k5lA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 41.0 2.94e-01 84.8% 76.8%
3lk7A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 35.0 3.31e-01 71.2% 82.6%
2fh5B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 43.0 3.21e-01 97.0% 49.5%
5je8B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 37.0 2.88e-01 77.3% 75.3%
4lxqB00 3.40.50.12230 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 44.0 2.98e-01 100.0% 70.8%
2yg5A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 38.0 2.84e-01 83.3% 91.2%
7uehA01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.51 37.0 3.09e-01 77.3% 77.8%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5082502 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.60 41.0 3.26e-01 71.2% 85.7%
5060907 2003.1.1.386 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Sacchrp_dh_C 0.58 47.0 3.03e-01 93.9% 45.0%
4982264 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.56 43.0 2.94e-01 86.4% 79.1%
5014504 2003.1.1.386 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Sacchrp_dh_C 0.55 45.0 2.92e-01 95.5% 45.2%
151025 2003.1.6.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like 0.54 45.0 3.45e-01 100.0% 71.5%
5037054 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.53 37.0 2.98e-01 74.2% 82.9%
3696240 2003.1.3.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › FAD_binding_3 0.52 42.0 2.56e-01 90.9% 69.7%
4238751 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.52 37.0 3.02e-01 77.3% 70.0%
1520169 7523.1.1.13 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Lipoprotein_9 0.51 36.0 3.07e-01 75.8% 66.1%
None — 0.51 36.0 2.70e-01 75.8% 76.8%
3598447 7528.1.1.5 ↗ a/b three-layered sandwiches › Phosphoglucomutase, first 3 domains › Phosphoglucomutase, first 3 domains › Phosphoglucomutase, first 3 domains › AMG1_II 0.51 38.0 2.93e-01 78.8% 66.9%
3657635 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.51 35.0 3.00e-01 74.2% 74.8%
3211131 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.51 36.0 2.94e-01 78.8% 46.4%
4676104 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.51 39.0 2.80e-01 84.8% 74.1%
D2 medium residues 210-390
PDB
Domain cluster: rep: ORF35__NP_733888__Callitrichine_gammaherpesvirus_3__106331__D45-78_114-298
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02689.21 best Herpes_Helicase 276.0 8.50e-82 100.0% 21.9%
D3 medium residues 415-476
PDB
Domain cluster: rep: helicase-primase_helicase_subunit__YP_068371__Suid_alphaherpesvirus_1__10345__D328-393
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02689.21 best Herpes_Helicase 84.4 7.30e-24 100.0% 7.3%
D4 medium residues 477-553_837-859
PDB
Domain cluster: rep: helicase-primase_helicase_subunit__NP_045354__Bovine_alphaherpesvirus_1__10320__D392-469_736-760
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02689.21 best Herpes_Helicase 85.8 2.80e-24 78.0% 9.5%
D5 medium residues 554-639_717-752
PDB
Domain cluster: rep: helicase-primase_helicase_subunit__YP_004940266__Saimiriine_betaherpesvirus_4__1535247__D509-572_638-677
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02689.21 best Herpes_Helicase 107.1 1.00e-30 70.5% 10.0%
D6 medium residues 753-802_819-836
PDB
Domain cluster: rep: JM73__YP_238376__Macaca_fuscata_rhadinovirus__272551__D601-676
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02689.21 best Herpes_Helicase 53.9 1.20e-14 100.0% 10.3%
D7 medium residues 860-922
PDB
Domain cluster: rep: helicase-primase_helicase_subunit__YP_009342401__Spheniscid_alphaherpesvirus_1__2560777__D779-840
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02689.21 best Herpes_Helicase 100.9 7.40e-29 100.0% 7.4%