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DNA_helicase_2
Euk-VirDrosophila_innubila_nudivirus
DNA_helicase_2__YP_009553154__Drosophila_innubila_nudivirus__2057187
Identity
- Accession:
- YP_009553154 ↗
- Protein ID:
- DNA_helicase_2
- Kingdom:
- euk
Quality
63.6
mean pLDDT
Taxonomy
TaxID: 2057187
Cluster
View cluster (5 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 701-852
D2
medium
residues 147-168_184-226_286-306_318-334
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3dmqA04 | 3.40.50.10810 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain | 0.71 | 64.0 | 4.51e-01 | 97.1% | 89.4% |
| 3l8dA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.61 | 54.0 | 4.35e-01 | 97.1% | 61.9% |
| 3fbtA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.61 | 51.0 | 4.73e-01 | 90.3% | 100.0% |
| 4ydsA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 53.0 | 4.17e-01 | 100.0% | 91.6% |
| 3eccA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 52.0 | 4.45e-01 | 94.2% | 97.5% |
| 2r44A02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.59 | 53.0 | 4.47e-01 | 98.1% | 94.0% |
| 2j8zA02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.58 | 49.0 | 4.39e-01 | 91.3% | 100.0% |
| 3ntvA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.58 | 50.0 | 4.06e-01 | 97.1% | 92.4% |
| 4hh4C01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.58 | 50.0 | 4.10e-01 | 96.1% | 81.1% |
| 2e28A03 | 3.40.1380.20 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain | 0.58 | 48.0 | 4.38e-01 | 89.3% | 87.4% |
| 3qtgA03 | 3.40.1380.20 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain | 0.57 | 48.0 | 4.61e-01 | 89.3% | 91.3% |
| 1wznA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.57 | 49.0 | 4.09e-01 | 97.1% | 83.0% |
| 7oo1A02 | 3.40.1380.20 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain | 0.57 | 46.0 | 4.40e-01 | 86.4% | 97.5% |
| 1ipaA02 | 3.40.1280.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain | 0.57 | 40.0 | 3.58e-01 | 74.8% | 83.0% |
| 3g8rA01 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.57 | 46.0 | 3.45e-01 | 87.4% | 87.1% |
| 1fuyB01 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 48.0 | 4.13e-01 | 95.1% | 76.2% |
| 4b4dA02 | 3.40.50.80 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module | 0.56 | 47.0 | 4.09e-01 | 94.2% | 98.1% |
| 3ccfA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.55 | 48.0 | 3.74e-01 | 100.0% | 92.9% |
| 1e0tA01 | 3.40.1380.20 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain | 0.54 | 44.0 | 4.17e-01 | 87.4% | 92.7% |
| 1a3wA01 | 3.40.1380.20 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain | 0.54 | 45.0 | 3.95e-01 | 90.3% | 80.6% |
| 3eoeD01 | 3.40.1380.20 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain | 0.53 | 44.0 | 3.99e-01 | 89.3% | 75.9% |
| 1b93B00 | 3.40.50.1380 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylglyoxal synthase-like domain | 0.52 | 41.0 | 3.65e-01 | 84.5% | 75.5% |
| 1gz0B02 | 3.40.1280.10 | Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain | 0.52 | 40.0 | 3.50e-01 | 83.5% | 79.6% |
| 2f62A00 | 3.40.50.450 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.52 | 37.0 | 3.24e-01 | 73.8% | 90.5% |
| 4relA02 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.50 | 39.0 | 3.33e-01 | 84.5% | 72.2% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4944925 | 2004.1.1.120 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII | 0.69 | 60.0 | 4.96e-01 | 93.2% | 90.3% |
| 5051568 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.64 | 57.0 | 4.57e-01 | 97.1% | 87.7% |
| 3576450 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.63 | 56.0 | 4.50e-01 | 98.1% | 91.0% |
| 3687167 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.61 | 44.0 | 4.29e-01 | 74.8% | 83.5% |
| 4314819 | 2004.1.1.58 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase | 0.60 | 55.0 | 4.40e-01 | 100.0% | 78.5% |
| 5003701 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.60 | 49.0 | 4.47e-01 | 89.3% | 84.9% |
| 4569056 | 2004.1.1.415 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA, RuvB_N | 0.59 | 53.0 | 4.28e-01 | 99.0% | 85.0% |
| 4949381 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.58 | 49.0 | 4.42e-01 | 90.3% | 88.5% |
| 5008886 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.58 | 48.0 | 4.44e-01 | 89.3% | 90.0% |
| 3744287 | 7515.1.1.0 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like | 0.58 | 50.0 | 3.85e-01 | 98.1% | 80.0% |
| 3391497 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.58 | 48.0 | 4.09e-01 | 89.3% | 74.5% |
| 5017650 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.58 | 47.0 | 4.32e-01 | 89.3% | 81.9% |
| 2801111 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.58 | 48.0 | 4.44e-01 | 89.3% | 92.2% |
| 5010230 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.58 | 48.0 | 4.54e-01 | 89.3% | 95.8% |
| 4944121 | 7518.1.1.0 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like | 0.57 | 47.0 | 4.36e-01 | 89.3% | 89.5% |
| 5049561 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.57 | 50.0 | 3.98e-01 | 95.1% | 87.8% |
| 3322739 | 2004.1.1.462 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NBD_SMAX1 | 0.57 | 50.0 | 4.16e-01 | 97.1% | 82.2% |
| 4026032 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.56 | 46.0 | 4.19e-01 | 89.3% | 89.3% |
| 3404546 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.56 | 46.0 | 4.12e-01 | 90.3% | 83.3% |
| 3200120 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.56 | 50.0 | 3.78e-01 | 100.0% | 83.5% |
| 3264060 | 2007.1.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like | 0.56 | 41.0 | 3.68e-01 | 75.7% | 78.6% |
| 3600856 | 7518.1.1.0 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like | 0.55 | 46.0 | 4.26e-01 | 90.3% | 93.3% |
| 3506784 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.55 | 48.0 | 3.80e-01 | 96.1% | 72.6% |
| 4065963 | 2003.1.5.3 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 | 0.54 | 48.0 | 3.62e-01 | 100.0% | 55.1% |
| 3599286 | 7518.1.1.0 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like | 0.54 | 44.0 | 4.06e-01 | 89.3% | 92.6% |
| 3590234 | 2004.1.1.63 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › FtsK_SpoIIIE | 0.53 | 42.0 | 3.86e-01 | 83.5% | 100.0% |
| 4147948 | 2488.1.1.1 ↗ | a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase | 0.52 | 41.0 | 3.56e-01 | 83.5% | 83.1% |
| 4997215 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.52 | 45.0 | 3.83e-01 | 97.1% | 81.1% |
D3
medium
residues 335-402_545-582
Domain cluster:
rep: helicase_2__YP_010087709__Homarus_gammarus_nudivirus__2509616__D258-315_421-469
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6jimB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.73 | 50.0 | 4.52e-01 | 70.8% | 64.3% |
| 3upuA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.71 | 65.0 | 6.07e-01 | 100.0% | 96.2% |
| 4b3fX03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 57.0 | 4.59e-01 | 100.0% | 79.2% |
| 2gk6A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 53.0 | 3.98e-01 | 95.3% | 81.1% |
| 3u4qB03 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 55.0 | 4.37e-01 | 100.0% | 80.3% |
| 4azcA02 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.61 | 26.0 | 3.42e-01 | 99.1% | 71.2% |
| 5eanA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 52.0 | 4.11e-01 | 100.0% | 78.7% |
| 3bigA02 | 3.40.190.90 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › | 0.55 | 46.0 | 4.01e-01 | 91.5% | 70.3% |
| 3c3jA01 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.53 | 41.0 | 3.45e-01 | 84.9% | 68.0% |
| 3vs8H00 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.51 | 44.0 | 3.01e-01 | 94.3% | 92.7% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3267758 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.73 | 65.0 | 5.91e-01 | 100.0% | 73.3% |
| 3385675 | 2004.1.1.298 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Herpes_Helicase | 0.73 | 65.0 | 5.77e-01 | 100.0% | 69.7% |
| 3596401 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.73 | 62.0 | 5.73e-01 | 100.0% | 71.9% |
| 3605939 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.69 | 63.0 | 5.77e-01 | 100.0% | 77.0% |
| 3600234 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.68 | 64.0 | 5.37e-01 | 100.0% | 76.5% |
| 3988979 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.66 | 51.0 | 5.04e-01 | 82.1% | 95.5% |
| 3414279 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.64 | 58.0 | 4.50e-01 | 100.0% | 79.1% |
| 4331804 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.64 | 58.0 | 4.71e-01 | 100.0% | 76.9% |
| 3265034 | 2004.1.1.186 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12 | 0.61 | 55.0 | 4.30e-01 | 100.0% | 71.6% |
| 4957823 | 2007.1.1.15 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › DUF2124 | 0.57 | 42.0 | 3.73e-01 | 78.3% | 77.5% |
| 4951921 | 2003.1.7.7 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › LUD_dom | 0.57 | 44.0 | 3.61e-01 | 84.9% | 84.9% |
| 3960707 | 7577.1.1.10 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › GDC-P | 0.56 | 42.0 | 3.44e-01 | 80.2% | 52.5% |
| 4257947 | 2003.1.5.79 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 | 0.53 | 42.0 | 3.38e-01 | 86.8% | 69.6% |
| 4987994 | 633.2.1.0 ↗ | alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein | 0.52 | 25.0 | 3.00e-01 | 100.0% | 68.6% |
| 4620939 | 2003.1.1.48 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › YjeF_N | 0.51 | 43.0 | 3.43e-01 | 93.4% | 92.0% |
D4
medium
residues 403-413_461-544