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DNA_helicase_primase
Euk-VirPithovirus_sibericum
DNA_helicase_primase__YP_009001273__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001273 ↗
- Protein ID:
- DNA_helicase_primase
- Kingdom:
- euk
Quality
68.2
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 71-161_178-222
Domain cluster:
rep: hypothetical_protein_H012_gp354__YP_007354538__Acanthamoeba_polyphaga_moumouvirus__1269028__D9-184
CATH (62)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2lqjA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.68 | 44.0 | 5.19e-01 | 94.9% | 94.7% |
| 3gz7B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 46.0 | 5.22e-01 | 96.3% | 95.9% |
| 1zpvA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.67 | 42.0 | 5.00e-01 | 97.1% | 98.8% |
| 4bpuC00 | 3.90.920.10 | Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain | 0.66 | 60.0 | 4.31e-01 | 97.8% | 72.5% |
| 4mt1A02 | 3.30.70.1430 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain | 0.65 | 47.0 | 5.26e-01 | 80.1% | 98.1% |
| 5abxA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.65 | 43.0 | 3.97e-01 | 95.6% | 52.0% |
| 5t0oA02 | 3.30.70.1430 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain | 0.65 | 47.0 | 5.25e-01 | 79.4% | 98.1% |
| 4limA00 | 3.90.920.10 | Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain | 0.65 | 60.0 | 4.26e-01 | 99.3% | 75.6% |
| 1q8bA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 43.0 | 5.00e-01 | 97.1% | 98.9% |
| 2rrnA01 | 3.30.70.2040 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 39.0 | 4.80e-01 | 96.3% | 98.8% |
| 4zosB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 44.0 | 5.05e-01 | 97.1% | 97.9% |
| 2pd1A01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 43.0 | 4.92e-01 | 95.6% | 95.8% |
| 2c2nA02 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.64 | 37.0 | 4.67e-01 | 93.4% | 100.0% |
| 2gffA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 44.0 | 5.00e-01 | 98.5% | 100.0% |
| 1m55A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.63 | 53.0 | 4.72e-01 | 89.7% | 96.9% |
| 4hl9A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 43.0 | 4.90e-01 | 96.3% | 100.0% |
| 1r89A03 | 3.30.70.590 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain | 0.62 | 50.0 | 5.09e-01 | 85.3% | 87.3% |
| 2f5gA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.62 | 44.0 | 4.50e-01 | 97.8% | 76.2% |
| 3e8oB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 42.0 | 4.77e-01 | 97.1% | 95.0% |
| 4mlaA03 | 3.40.462.10 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › FAD-linked oxidases, C-terminal domain | 0.61 | 47.0 | 3.96e-01 | 79.4% | 82.1% |
| 4dpoB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 42.0 | 4.70e-01 | 95.6% | 94.1% |
| 1iujA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 43.0 | 4.83e-01 | 97.8% | 98.0% |
| 2y1rK00 | 3.30.70.1950 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 40.0 | 4.67e-01 | 76.5% | 97.8% |
| 1x7vA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 42.0 | 4.79e-01 | 97.1% | 100.0% |
| 1f3vA00 | 3.30.70.680 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TRADD, N-terminal domain | 0.60 | 44.0 | 4.22e-01 | 77.2% | 93.7% |
| 1xmbA02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 42.0 | 4.82e-01 | 100.0% | 98.0% |
| 2fiuA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 41.0 | 4.67e-01 | 96.3% | 100.0% |
| 2mq8A00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.60 | 42.0 | 4.58e-01 | 97.1% | 89.3% |
| 4x0qA03 | 3.30.70.370 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 38.0 | 3.81e-01 | 94.1% | 62.2% |
| 4kw3A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.59 | 49.0 | 3.96e-01 | 90.4% | 97.4% |
| 3vteA03 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.59 | 45.0 | 4.05e-01 | 80.1% | 82.7% |
| 3rjaA02 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.59 | 48.0 | 4.04e-01 | 87.5% | 95.6% |
| 1x31C02 | 3.30.70.1520 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Heterotetrameric sarcosine oxidase | 0.58 | 34.0 | 4.29e-01 | 93.4% | 100.0% |
| 4djbA00 | 3.30.70.2870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 | 0.58 | 46.0 | 4.93e-01 | 97.1% | 98.3% |
| 3fw9A03 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.57 | 44.0 | 3.98e-01 | 80.1% | 81.0% |
| 2bvfA03 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.57 | 46.0 | 4.05e-01 | 87.5% | 99.0% |
| 1zr6A03 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.57 | 46.0 | 4.06e-01 | 87.5% | 99.0% |
| 5l6gA02 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.57 | 46.0 | 3.89e-01 | 87.5% | 95.6% |
| 4ud8A03 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.56 | 43.0 | 3.89e-01 | 80.1% | 81.5% |
| 4c8yA01 | 3.30.70.1890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 41.0 | 4.57e-01 | 95.6% | 100.0% |
| 5axmB00 | 3.30.70.3000 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) | 0.56 | 49.0 | 4.12e-01 | 97.8% | 95.8% |
| 1tuwA00 | 3.30.70.1090 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. | 0.56 | 40.0 | 4.46e-01 | 97.1% | 97.2% |
| 3h7hB00 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.56 | 37.0 | 4.25e-01 | 72.1% | 96.8% |
| 3mcnA01 | 3.30.70.560 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK | 0.56 | 47.0 | 4.63e-01 | 94.9% | 85.0% |
| 4er8A00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.55 | 47.0 | 4.47e-01 | 93.4% | 89.7% |
| 5d79A03 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.55 | 42.0 | 3.83e-01 | 80.1% | 79.7% |
| 1f08B00 | 3.40.1310.10 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.55 | 44.0 | 4.30e-01 | 89.0% | 78.6% |
| 1qd1B02 | 3.30.70.670 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Formiminotransferase, C-terminal subdomain | 0.55 | 39.0 | 3.87e-01 | 99.3% | 68.3% |
| 4d53A00 | 3.40.33.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pathogenesis-related Protein p14a › CAP | 0.55 | 30.0 | 3.12e-01 | 98.5% | 54.9% |
| 3mcsA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 49.0 | 4.21e-01 | 98.5% | 97.7% |
| 4cyuA00 | 3.30.70.560 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK | 0.55 | 48.0 | 4.60e-01 | 94.9% | 86.4% |
| 3znuA00 | 3.30.70.1060 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel | 0.54 | 37.0 | 4.22e-01 | 98.5% | 100.0% |
| 2abyA00 | 3.30.70.1980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF09406, DUF2004 | 0.54 | 41.0 | 4.36e-01 | 92.6% | 91.0% |
| 1r9wA00 | 3.40.1310.10 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.53 | 41.0 | 4.13e-01 | 91.2% | 81.2% |
| 3f44A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 47.0 | 4.10e-01 | 98.5% | 99.0% |
| 2exuA02 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.52 | 35.0 | 3.95e-01 | 71.3% | 96.8% |
| 1ab8A00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.52 | 46.0 | 4.22e-01 | 95.6% | 76.3% |
| 5yjlB01 | 3.30.460.30 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Glutamyl-tRNA reductase, N-terminal domain | 0.52 | 44.0 | 4.20e-01 | 91.9% | 90.7% |
| 2kcuA00 | 3.20.80.10 | Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain | 0.52 | 42.0 | 3.99e-01 | 86.8% | 81.3% |
| 3u02A01 | 3.30.70.2200 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 44.0 | 4.35e-01 | 91.9% | 100.0% |
| 4pvkA03 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.51 | 41.0 | 3.81e-01 | 86.8% | 76.8% |
| 5tkwA01 | 3.30.420.380 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › | 0.51 | 32.0 | 3.01e-01 | 95.6% | 48.8% |
ECOD (59)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3677440 | 862.1.1.11 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › AEP_C962R | 0.80 | 76.0 | 6.06e-01 | 100.0% | 71.4% |
| 3802060 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.79 | 75.0 | 5.96e-01 | 100.0% | 68.2% |
| 4540833 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.72 | 44.0 | 5.37e-01 | 94.1% | 97.6% |
| 5024024 | 304.16.1.1 ↗ | a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE | 0.70 | 46.0 | 5.31e-01 | 97.1% | 94.7% |
| 4416593 | 304.28.1.4 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st | 0.70 | 46.0 | 5.46e-01 | 94.9% | 100.0% |
| 4932448 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.69 | 45.0 | 5.40e-01 | 96.3% | 100.0% |
| 3729382 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.67 | 47.0 | 5.17e-01 | 97.8% | 89.1% |
| 5043596 | 304.15.1.0 ↗ | a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain | 0.67 | 47.0 | 5.11e-01 | 95.6% | 86.1% |
| 3348724 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.66 | 47.0 | 5.26e-01 | 76.5% | 95.2% |
| 5081312 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.66 | 62.0 | 5.19e-01 | 100.0% | 67.3% |
| 3215882 | 304.8.1.72 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › SCVP | 0.65 | 41.0 | 4.83e-01 | 95.6% | 94.4% |
| 4880004 | 304.55.1.7 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Rep_N | 0.65 | 53.0 | 4.63e-01 | 87.5% | 91.3% |
| 4012488 | 304.4.1.4 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM | 0.65 | 43.0 | 4.98e-01 | 97.1% | 96.8% |
| 4051078 | 304.4.1.71 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › DUF4937 | 0.63 | 47.0 | 5.08e-01 | 78.7% | 100.0% |
| 4133039 | 304.8.1.81 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › REP_ORF2-G2P | 0.62 | 48.0 | 4.49e-01 | 80.1% | 86.7% |
| 4667955 | 304.150.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain | 0.61 | 42.0 | 4.84e-01 | 77.2% | 100.0% |
| 5005568 | 304.28.1.38 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › CAA_C | 0.61 | 49.0 | 4.58e-01 | 86.0% | 93.5% |
| 4032691 | 304.150.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA | 0.61 | 41.0 | 4.72e-01 | 77.2% | 97.9% |
| 4350848 | 304.150.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA | 0.60 | 41.0 | 4.75e-01 | 75.7% | 98.9% |
| 3460420 | 304.51.1.0 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related | 0.60 | 43.0 | 4.79e-01 | 96.3% | 96.2% |
| 2721342 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.59 | 48.0 | 3.88e-01 | 87.5% | 82.2% |
| 1711357 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.59 | 48.0 | 3.83e-01 | 86.0% | 82.3% |
| 4219489 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.58 | 48.0 | 3.80e-01 | 87.5% | 80.7% |
| 4312788 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.58 | 48.0 | 3.80e-01 | 87.5% | 82.5% |
| 3685983 | 304.6.1.0 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain | 0.58 | 47.0 | 3.88e-01 | 87.5% | 83.6% |
| 4982409 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.58 | 46.0 | 4.24e-01 | 85.3% | 88.3% |
| 1887045 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.57 | 46.0 | 3.69e-01 | 86.8% | 82.4% |
| 4342843 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.57 | 46.0 | 3.81e-01 | 87.5% | 83.7% |
| 5024461 | 304.28.1.38 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › CAA_C | 0.56 | 48.0 | 4.48e-01 | 90.4% | 94.5% |
| 3952578 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.56 | 46.0 | 3.84e-01 | 87.5% | 83.3% |
| 4104254 | 304.17.1.2 ↗ | a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN | 0.56 | 37.0 | 4.14e-01 | 72.1% | 86.7% |
| 4089147 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.56 | 45.0 | 3.71e-01 | 87.5% | 81.5% |
| 2605091 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.56 | 44.0 | 3.55e-01 | 85.3% | 78.8% |
| 4054638 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.56 | 46.0 | 4.33e-01 | 89.7% | 90.0% |
| 4139791 | 304.41.1.1 ↗ | a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N | 0.56 | 47.0 | 4.46e-01 | 91.9% | 92.5% |
| 3168157 | 304.17.1.2 ↗ | a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN | 0.56 | 37.0 | 4.21e-01 | 72.1% | 92.0% |
| 3937461 | 304.151.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase | 0.56 | 41.0 | 4.47e-01 | 95.6% | 95.5% |
| 4092955 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.56 | 47.0 | 4.41e-01 | 90.4% | 94.5% |
| 5028094 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.56 | 47.0 | 4.27e-01 | 91.9% | 92.4% |
| 3256537 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.55 | 45.0 | 3.76e-01 | 87.5% | 82.5% |
| 3180053 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.55 | 44.0 | 3.65e-01 | 87.5% | 83.9% |
| 4011256 | 304.6.1.0 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain | 0.55 | 44.0 | 3.66e-01 | 88.2% | 83.9% |
| 3686788 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.54 | 43.0 | 3.41e-01 | 85.3% | 85.4% |
| 3447791 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.54 | 43.0 | 3.45e-01 | 87.5% | 77.5% |
| 3638202 | 304.6.1.0 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain | 0.54 | 43.0 | 3.68e-01 | 87.5% | 97.4% |
| 4552979 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.53 | 46.0 | 4.36e-01 | 92.6% | 94.4% |
| 4018430 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.53 | 43.0 | 3.58e-01 | 86.0% | 80.0% |
| 4015323 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.53 | 42.0 | 3.56e-01 | 87.5% | 84.4% |
| 3192994 | 304.6.1.0 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain | 0.53 | 42.0 | 3.27e-01 | 85.3% | 86.1% |
| 3727919 | 304.6.1.0 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain | 0.53 | 43.0 | 3.53e-01 | 88.2% | 80.4% |
| 3250368 | 304.4.1.8 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › rhaM | 0.52 | 40.0 | 4.27e-01 | 97.8% | 94.2% |
| 5003409 | 886.1.1.1 ↗ | a+b duplicates or obligate multimers › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › SOUL | 0.52 | 45.0 | 4.26e-01 | 93.4% | 87.5% |
| 4621809 | 304.6.1.0 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain | 0.51 | 42.0 | 3.43e-01 | 89.7% | 84.1% |
| 4990743 | 304.42.1.1 ↗ | a+b two layers › Alpha-beta plaits › Molybdenum cofactor biosynthesis protein C, MoaC › Molybdenum cofactor biosynthesis protein C, MoaC › MoaC | 0.51 | 35.0 | 3.89e-01 | 95.6% | 91.4% |
| 4054258 | 2484.1.1.47 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › T2SSL | 0.51 | 32.0 | 3.23e-01 | 94.9% | 60.0% |
| 1892335 | 2484.1.1.47 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › T2SSL | 0.51 | 32.0 | 3.14e-01 | 95.6% | 55.7% |
| 3237694 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.51 | 43.0 | 4.34e-01 | 94.9% | 100.0% |
| 4443361 | 304.55.2.7 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f | 0.51 | 44.0 | 3.70e-01 | 94.1% | 95.1% |
| 4438667 | 304.42.1.0 ↗ | a+b two layers › Alpha-beta plaits › Molybdenum cofactor biosynthesis protein C, MoaC › Molybdenum cofactor biosynthesis protein C, MoaC | 0.50 | 34.0 | 3.79e-01 | 97.1% | 90.5% |
D2
high
residues 232-314
Domain cluster:
rep: origin_of_replication-binding_protein__YP_009345580__Noumeavirus__1955558__D365-435
CATH (51)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3dcdA00 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.66 | 55.0 | 3.75e-01 | 91.6% | 96.3% |
| 3k25A00 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.65 | 55.0 | 3.78e-01 | 92.8% | 95.1% |
| 2qmiA02 | 2.40.128.210 | Mainly Beta › Beta Barrel › Lipocalin › Pab87 octamerisation domain | 0.64 | 55.0 | 5.22e-01 | 95.2% | 95.0% |
| 3ci0J01 | 3.10.610.10 | Alpha Beta › Roll › Pili subunits › GSPII I/J protein-like | 0.64 | 48.0 | 4.44e-01 | 79.5% | 94.2% |
| 2pagA00 | 3.40.1580.10 | Alpha Beta › 3-Layer(aba) Sandwich › SMI1/KNR4-like › SMI1/KNR4-like | 0.61 | 43.0 | 3.69e-01 | 90.4% | 46.2% |
| 3kyaA02 | 2.120.10.30 | Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain | 0.61 | 48.0 | 3.16e-01 | 86.7% | 40.1% |
| 1ixlA00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.60 | 52.0 | 4.55e-01 | 98.8% | 93.8% |
| 2d4rA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.57 | 46.0 | 3.83e-01 | 88.0% | 57.5% |
| 7snsB01 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.57 | 47.0 | 3.82e-01 | 92.8% | 72.2% |
| 5i4nA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.57 | 40.0 | 3.91e-01 | 74.7% | 88.0% |
| 2l1tA00 | 2.30.110.70 | Mainly Beta › Roll › Pnp Oxidase; Chain A › | 0.56 | 40.0 | 3.69e-01 | 74.7% | 83.5% |
| 2gu1A02 | 3.10.450.350 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.56 | 49.0 | 4.55e-01 | 98.8% | 95.2% |
| 3zxfA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.55 | 47.0 | 3.95e-01 | 92.8% | 77.8% |
| 3ligA02 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.55 | 49.0 | 3.89e-01 | 100.0% | 81.1% |
| 1a78A00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.55 | 47.0 | 3.96e-01 | 92.8% | 78.4% |
| 3ap9A00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 48.0 | 3.99e-01 | 100.0% | 80.8% |
| 5ocrA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 48.0 | 3.34e-01 | 100.0% | 78.4% |
| 2wsuB02 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 46.0 | 3.85e-01 | 94.0% | 75.7% |
| 5ocqA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 48.0 | 3.36e-01 | 100.0% | 80.1% |
| 4ym3C00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 48.0 | 4.05e-01 | 98.8% | 82.9% |
| 5nslA02 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.54 | 48.0 | 3.67e-01 | 100.0% | 66.8% |
| 5nldB00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 46.0 | 3.90e-01 | 94.0% | 75.4% |
| 4agrB00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 46.0 | 3.80e-01 | 92.8% | 74.3% |
| 3zsjA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 46.0 | 3.88e-01 | 94.0% | 75.4% |
| 2e3nA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.54 | 47.0 | 3.47e-01 | 100.0% | 95.2% |
| 3qeeB00 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.54 | 44.0 | 3.08e-01 | 94.0% | 92.0% |
| 1x23B00 | 3.10.110.10 | Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme | 0.54 | 43.0 | 3.60e-01 | 90.4% | 61.2% |
| 6e20A00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 46.0 | 3.93e-01 | 94.0% | 79.5% |
| 5gm0A01 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 45.0 | 3.73e-01 | 92.8% | 71.6% |
| 2joxA00 | 2.60.40.4240 | Mainly Beta › Sandwich › Immunoglobulin-like › Transcription activator, Churchill | 0.53 | 38.0 | 3.52e-01 | 74.7% | 80.2% |
| 5xrkA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 45.0 | 3.79e-01 | 92.8% | 74.5% |
| 1hlcA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 46.0 | 3.94e-01 | 94.0% | 78.3% |
| 4ccdA03 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.53 | 47.0 | 3.59e-01 | 100.0% | 83.5% |
| 6n44A00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 46.0 | 3.85e-01 | 94.0% | 75.5% |
| 3uaqB02 | 2.40.160.90 | Mainly Beta › Beta Barrel › Porin › | 0.53 | 42.0 | 3.49e-01 | 90.4% | 59.5% |
| 2wsuA01 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.53 | 47.0 | 3.96e-01 | 97.6% | 80.6% |
| 1w2tA02 | 2.60.120.560 | Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 | 0.53 | 47.0 | 4.04e-01 | 100.0% | 76.1% |
| 2v43A01 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.53 | 44.0 | 3.49e-01 | 94.0% | 89.1% |
| 1lc5A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.53 | 43.0 | 3.79e-01 | 90.4% | 60.0% |
| 3npfB01 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.52 | 34.0 | 3.75e-01 | 84.3% | 83.3% |
| 5dzeA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 46.0 | 3.53e-01 | 100.0% | 75.4% |
| 1gbgA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 46.0 | 3.46e-01 | 100.0% | 78.5% |
| 2mouA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.52 | 46.0 | 3.41e-01 | 100.0% | 71.4% |
| 6xofA01 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 46.0 | 3.30e-01 | 100.0% | 78.7% |
| 2wkkA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 45.0 | 3.72e-01 | 96.4% | 76.0% |
| 1d2sA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 44.0 | 3.50e-01 | 94.0% | 58.2% |
| 1c1fA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 45.0 | 3.82e-01 | 96.4% | 79.3% |
| 1ukfA00 | 3.90.70.20 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › | 0.51 | 42.0 | 3.24e-01 | 90.4% | 42.0% |
| 5h66A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 43.0 | 3.41e-01 | 97.6% | 54.5% |
| 1xd3C00 | 3.40.532.10 | Alpha Beta › 3-Layer(aba) Sandwich › Ubiquitin C-terminal Hydrolase UCH-l3 › Peptidase C12, ubiquitin carboxyl-terminal hydrolase | 0.51 | 46.0 | 3.33e-01 | 100.0% | 78.9% |
| 4tyzA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.50 | 38.0 | 3.50e-01 | 81.9% | 76.1% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3719984 | 243.16.1.0 ↗ | a+b two layers › Cystatin-like › hypothetical protein CLOLEP_02462 › hypothetical protein CLOLEP_02462 | 0.71 | 63.0 | 5.17e-01 | 100.0% | 93.5% |
| 3211631 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.63 | 46.0 | 3.18e-01 | 81.9% | 23.8% |
| 3697524 | 9.2.1.7 ↗ | beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › PF30970 | 0.62 | 49.0 | 4.80e-01 | 85.5% | 81.1% |
| 4009137 | 274.1.1.12 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits › T2SSJ | 0.62 | 47.0 | 3.70e-01 | 80.7% | 49.4% |
| 3511117 | 9.1.1.12 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › THAP4_heme-bd | 0.61 | 51.0 | 4.16e-01 | 94.0% | 95.8% |
| 3480143 | 241.15.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain | 0.60 | 51.0 | 4.21e-01 | 92.8% | 67.3% |
| 5059099 | 241.2.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › Frataxin-like › Frataxin-like | 0.60 | 48.0 | 4.70e-01 | 89.2% | 80.7% |
| 3988064 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.60 | 45.0 | 4.79e-01 | 80.7% | 100.0% |
| 3926131 | 331.3.1.3 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START | 0.59 | 46.0 | 3.36e-01 | 84.3% | 37.0% |
| 3269422 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.59 | 44.0 | 3.10e-01 | 79.5% | 29.3% |
| 3243587 | 2484.1.1.200 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FTH | 0.59 | 42.0 | 2.79e-01 | 74.7% | 22.9% |
| 3226910 | 2484.1.1.200 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › FTH | 0.59 | 42.0 | 3.05e-01 | 74.7% | 32.7% |
| 4929053 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.58 | 43.0 | 4.57e-01 | 80.7% | 94.3% |
| 3635423 | 844.1.1.0 ↗ | beta barrels › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain › Transcriptional factor tubby, C-terminal domain | 0.57 | 48.0 | 3.66e-01 | 96.4% | 41.1% |
| 3578918 | 331.3.1.3 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START | 0.56 | 40.0 | 3.45e-01 | 74.7% | 49.6% |
| 3258463 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.56 | 36.0 | 3.77e-01 | 89.2% | 72.0% |
| 5014638 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.55 | 49.0 | 4.04e-01 | 98.8% | 79.3% |
| 3901954 | 10.1.1.4 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Gal-bind_lectin | 0.55 | 47.0 | 3.88e-01 | 92.8% | 72.9% |
| 4383747 | 220.1.1.8 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM | 0.54 | 43.0 | 3.52e-01 | 85.5% | 55.5% |
| 3746679 | 216.1.1.4 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like › RWD | 0.54 | 44.0 | 3.90e-01 | 90.4% | 72.0% |
| 2462227 | 10.1.1.4 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Gal-bind_lectin | 0.54 | 46.0 | 3.95e-01 | 94.0% | 78.2% |
| 3798404 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.54 | 45.0 | 3.77e-01 | 92.8% | 73.1% |
| 3183973 | 10.1.1.26 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Glyco_hydro_32C | 0.54 | 48.0 | 3.90e-01 | 100.0% | 76.8% |
| 3429522 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.54 | 43.0 | 2.84e-01 | 88.0% | 46.9% |
| 2588563 | 10.1.1.4 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Gal-bind_lectin | 0.53 | 45.0 | 3.76e-01 | 92.8% | 73.9% |
| 3821609 | 2004.1.1.442 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21 | 0.53 | 45.0 | 2.77e-01 | 97.6% | 20.2% |
| 3315173 | 243.3.1.46 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › SWIM | 0.53 | 39.0 | 3.56e-01 | 79.5% | 87.8% |
| 3472659 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.53 | 41.0 | 3.55e-01 | 86.7% | 73.6% |
| 3494266 | 331.4.1.5 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › KA1_BRSK | 0.53 | 43.0 | 3.86e-01 | 90.4% | 86.7% |
| 3930230 | 331.4.1.5 ↗ | a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › KA1_BRSK | 0.53 | 43.0 | 3.89e-01 | 90.4% | 80.0% |
| 4481031 | 10.1.1.11 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Glyco_hydro_16 | 0.52 | 47.0 | 3.36e-01 | 100.0% | 78.4% |
| 3680270 | 2004.1.1.567 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23 | 0.52 | 44.0 | 2.78e-01 | 97.6% | 21.6% |
| 3869913 | 2004.1.1.442 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21 | 0.52 | 45.0 | 2.89e-01 | 98.8% | 23.9% |
| 3915989 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.52 | 44.0 | 2.60e-01 | 97.6% | 12.9% |
| 3182497 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.52 | 44.0 | 2.84e-01 | 97.6% | 24.2% |
| 4942135 | 9.2.1.0 ↗ | beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin | 0.52 | 40.0 | 3.60e-01 | 86.7% | 72.6% |
| 29947 | 10.1.1.4 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Gal-bind_lectin | 0.52 | 45.0 | 3.82e-01 | 96.4% | 79.3% |
| 3254045 | 5084.5.1.3 ↗ | beta barrels › Outer membrane meander beta-barrels › Porins › Porin › Porin_3 | 0.51 | 44.0 | 3.10e-01 | 98.8% | 69.4% |
| 4021196 | 270.1.1.0 ↗ | beta barrels › FMT C-terminal domain-like › FMT C-terminal domain-related › FMT C-terminal domain-related | 0.50 | 35.0 | 3.07e-01 | 73.5% | 76.3% |
| 4504274 | 7515.1.1.2 ↗ | a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Sulfatase | 0.50 | 43.0 | 2.83e-01 | 97.6% | 78.3% |
| 4468812 | 10.1.1.1 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_1 | 0.50 | 42.0 | 3.22e-01 | 92.8% | 49.7% |
D3
medium
residues 1-70_162-177
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4g54A01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.62 | 47.0 | 4.18e-01 | 81.4% | 90.4% |
| 2jveA00 | 2.10.60.10 | Mainly Beta › Ribbon › CD59 › CD59 | 0.61 | 43.0 | 4.69e-01 | 80.2% | 90.1% |
| 2hiyA02 | 3.30.70.1260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › bacterial protein sp0830 like | 0.58 | 42.0 | 4.15e-01 | 75.6% | 93.5% |
| 3lurA00 | 3.20.80.10 | Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain | 0.58 | 47.0 | 3.93e-01 | 90.7% | 91.1% |
| 2jvfA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.57 | 39.0 | 3.88e-01 | 72.1% | 100.0% |
| 5xbtA01 | 3.20.80.10 | Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain | 0.55 | 46.0 | 3.84e-01 | 90.7% | 93.9% |
| 1qysA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.55 | 37.0 | 3.71e-01 | 70.9% | 100.0% |
| 1x67A01 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.54 | 44.0 | 3.83e-01 | 89.5% | 65.4% |
| 2onsA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.53 | 44.0 | 3.84e-01 | 97.7% | 88.8% |
| 2qsdB02 | 3.50.100.10 | Alpha Beta › 3-Layer(bba) Sandwich › protein il1583 fold › protein il1583 domain | 0.52 | 36.0 | 3.74e-01 | 70.9% | 82.1% |
| 2d8bA01 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.52 | 40.0 | 3.54e-01 | 88.4% | 91.4% |
| 1hqz800 | 3.40.20.10 | Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin | 0.52 | 42.0 | 3.67e-01 | 89.5% | 65.2% |
| 1uscA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.51 | 42.0 | 3.46e-01 | 95.3% | 70.2% |
| 2q0oA01 | 3.30.450.80 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain | 0.50 | 35.0 | 2.90e-01 | 73.3% | 76.8% |
| 2x2zD01 | 3.50.4.10 | Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor | 0.50 | 40.0 | 3.41e-01 | 89.5% | 68.9% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3512046 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.84 | 76.0 | 5.19e-01 | 94.2% | 82.0% |
| 3802060 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.83 | 75.0 | 5.16e-01 | 95.3% | 80.0% |
| 3677440 | 862.1.1.11 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › AEP_C962R | 0.82 | 74.0 | 5.18e-01 | 95.3% | 83.7% |
| 3937694 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.82 | 74.0 | 5.07e-01 | 96.5% | 78.1% |
| 3717917 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.80 | 74.0 | 4.71e-01 | 97.7% | 78.5% |
| 3608399 | 862.1.1.7 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › PPL5 | 0.79 | 70.0 | 5.02e-01 | 95.3% | 77.9% |
| 3596656 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.79 | 72.0 | 4.92e-01 | 97.7% | 80.7% |
| 4973396 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.61 | 43.0 | 3.34e-01 | 73.3% | 75.0% |
| 5018277 | 5103.1.1.0 ↗ | a/b three-layered sandwiches › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 › Insert domain in hypothetical protein PF0380 | 0.59 | 43.0 | 4.11e-01 | 76.7% | 90.0% |
| 3179413 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.59 | 50.0 | 3.40e-01 | 96.5% | 59.1% |
| 3209196 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.58 | 51.0 | 3.43e-01 | 100.0% | 55.4% |
| 5056019 | 886.1.1.5 ↗ | a+b duplicates or obligate multimers › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Bact_hydrolase | 0.58 | 48.0 | 4.09e-01 | 90.7% | 92.9% |
| 3929549 | 382.1.1.0 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like | 0.57 | 43.0 | 3.82e-01 | 81.4% | 94.6% |
| 3920703 | 10.12.1.40 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › JmjC_2 | 0.57 | 40.0 | 2.73e-01 | 73.3% | 46.9% |
| 3915843 | 382.1.1.0 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like | 0.57 | 33.0 | 3.95e-01 | 75.6% | 90.9% |
| 3428340 | 390.1.1.6 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_2 | 0.56 | 38.0 | 3.83e-01 | 77.9% | 70.6% |
| 3625936 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.55 | 40.0 | 3.96e-01 | 77.9% | 74.7% |
| 2723799 | 382.1.1.7 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › Toxin_cobra-type | 0.54 | 35.0 | 3.69e-01 | 77.9% | 73.7% |
| 3236076 | 382.1.1.17 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › ET | 0.54 | 41.0 | 4.05e-01 | 80.2% | 87.8% |
| 3936711 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.54 | 39.0 | 4.16e-01 | 79.1% | 90.7% |
| 3505196 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.54 | 39.0 | 3.97e-01 | 79.1% | 82.4% |
| 3212789 | 382.1.1.17 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › ET | 0.53 | 40.0 | 3.95e-01 | 79.1% | 91.1% |
| 4212253 | 304.150.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA | 0.53 | 40.0 | 3.94e-01 | 81.4% | 98.9% |
| 3923618 | 382.1.1.0 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like | 0.53 | 39.0 | 3.84e-01 | 79.1% | 94.7% |
| 4245789 | 304.150.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA | 0.53 | 39.0 | 3.90e-01 | 80.2% | 100.0% |
| 3516508 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.52 | 39.0 | 3.97e-01 | 80.2% | 81.2% |
| 4288170 | 3292.1.1.1 ↗ | a+b complex topology › Adenine deaminase 2 C-terminal domain › Adenine deaminase 2 C-terminal domain › Adenine deaminase 2 C-terminal domain › Adenine_deam_C | 0.52 | 43.0 | 3.23e-01 | 89.5% | 61.0% |
| 3933162 | 382.1.1.0 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like | 0.52 | 40.0 | 3.91e-01 | 86.0% | 90.0% |
| 3385583 | 288.1.1.1 ↗ | a+b four layers › CNF1/YfiH-like putative cysteine hydrolases › CNF1/YfiH-like putative cysteine hydrolases › CNF1/YfiH-like putative cysteine hydrolases › Cu-oxidase_4 | 0.52 | 44.0 | 3.37e-01 | 97.7% | 58.6% |
| 4447947 | 3292.1.1.1 ↗ | a+b complex topology › Adenine deaminase 2 C-terminal domain › Adenine deaminase 2 C-terminal domain › Adenine deaminase 2 C-terminal domain › Adenine_deam_C | 0.52 | 42.0 | 3.21e-01 | 88.4% | 63.0% |
| 3368071 | 390.1.1.0 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like | 0.51 | 36.0 | 3.66e-01 | 77.9% | 74.1% |
| None | — | 0.51 | 39.0 | 2.91e-01 | 84.9% | 91.4% | |
| 3820637 | 390.1.1.6 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_2 | 0.51 | 36.0 | 3.73e-01 | 77.9% | 78.8% |
| 3941259 | 382.1.1.18 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › DUF7741 | 0.50 | 37.0 | 3.89e-01 | 80.2% | 90.0% |