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DNA_packaging_tegument_protein_UL25
Euk-VirMacacine_alphaherpesvirus_1
DNA_packaging_tegument_protein_UL25__NP_851884__Macacine_alphaherpesvirus_1__10325
Identity
- Accession:
- NP_851884 ↗
- Protein ID:
- DNA_packaging_tegument_protein_UL25
- Kingdom:
- euk
Quality
77.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Macacine_alphaherpesvirus_1
TaxID: 10325
Cluster
View cluster (77 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 170-227
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01499.22 best | Herpes_UL25 | 64.8 | 8.90e-18 | 100.0% | 9.6% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2pjqA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.55 | 41.0 | 3.63e-01 | 82.8% | 98.9% |
| 1vwxQ00 | 3.100.10.10 | Alpha Beta › Ribosomal Protein L15; Chain: K; domain 2 › Ribosomal Protein L15; Chain: K; domain 2 › | 0.53 | 43.0 | 3.13e-01 | 94.8% | 54.5% |
| 5f1cA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.50 | 37.0 | 3.69e-01 | 79.3% | 79.7% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5034082 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.69 | 52.0 | 3.81e-01 | 82.8% | 50.6% |
| 4369884 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.58 | 37.0 | 3.74e-01 | 86.2% | 63.3% |
| 3730946 | 3924.1.1.0 ↗ | alpha complex topology › Sterol uptake control protein 2 › Sterol uptake control protein 2 › Sterol uptake control protein 2 | 0.52 | 41.0 | 3.00e-01 | 91.4% | 65.4% |
D2
medium
residues 228-332_346-356
Domain cluster:
rep: DNA_packaging_tegument_protein_UL25__YP_010085894__Wood_mouse_herpesvirus__432370__D202-318
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01499.22 best | Herpes_UL25 | 94.4 | 9.40e-27 | 100.0% | 21.4% |
D3
medium
residues 368-414_434-475_487-579
Domain cluster:
rep: DNA_packaging_tegument_protein_UL25__YP_009054940__Equid_alphaherpesvirus_3__80341__D158-233_380-417_449-491_503-595
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01499.22 best | Herpes_UL25 | 162.3 | 2.50e-47 | 87.9% | 34.4% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2y1eA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.66 | 24.0 | 3.40e-01 | 72.5% | 66.7% |
| 2e62A01 | 6.10.140.420 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 18.0 | 3.43e-01 | 70.3% | 96.2% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 21.0 | 3.51e-01 | 70.3% | 96.9% |
| 8h8jC01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 40.0 | 3.52e-01 | 79.1% | 92.6% |
| 6mh4A03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.51 | 24.0 | 3.26e-01 | 95.1% | 92.4% |
| 4mbsA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 40.0 | 3.24e-01 | 81.9% | 91.9% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.51 | 25.0 | 3.46e-01 | 82.4% | 100.0% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 39.0 | 3.41e-01 | 80.2% | 89.8% |
| 1q5nA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.51 | 40.0 | 3.64e-01 | 81.9% | 93.4% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.50 | 24.0 | 3.56e-01 | 92.3% | 98.9% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 39.0 | 3.32e-01 | 81.3% | 90.1% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 185949 | 3424.1.1.1 ↗ | alpha arrays › Virion protein UL25 › Virion protein UL25 › Virion protein UL25 › Herpes_UL25 | 0.96 | 92.0 | 6.74e-01 | 98.4% | 46.8% |
| 3503444 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.59 | 28.0 | 4.06e-01 | 73.6% | 94.4% |
| 3997160 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.55 | 26.0 | 3.50e-01 | 90.7% | 83.0% |
| 3987542 | 1079.1.1.1 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD | 0.52 | 35.0 | 3.25e-01 | 95.1% | 53.0% |
| 4938848 | 5069.1.3.131 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF92 | 0.51 | 21.0 | 2.81e-01 | 74.7% | 67.0% |
| 4031537 | 159.1.2.0 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related | 0.51 | 27.0 | 3.73e-01 | 91.8% | 97.0% |