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DNA_polymerase_-2-

Euk-Vir

Monkeypox_virus

DNA_polymerase_-2-__YP_010377054__Monkeypox_virus__10244

Identity

Accession:
YP_010377054 ↗
Protein ID:
DNA_polymerase_-2-
Kingdom:
euk

Quality

84.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Monkeypox_virus

TaxID: 10244

Cluster

View cluster (158 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 162-344_438-473
PDB
Domain cluster: rep: DNA_polymerase_catalytic_subunit__YP_401712__Human_gammaherpesvirus_4__10376__D288-457
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF03104.26 best DNA_pol_B_exo1 74.4 1.30e-20 86.3% 69.8%
PF08408.17 DNA_pol_B_3 63.1 4.10e-17 36.1% 28.1%
D2 high residues 351-432
PDB
Domain cluster: rep: DNA_polymerase_elongation_subunit_family_B__YP_009162448__Salmon_gill_poxvirus__1680908__D388-474
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08408.17 best DNA_pol_B_3 74.5 1.30e-20 100.0% 64.1%
CATH (75)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6oqrA01 2.40.30.20 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.75 56.0 5.48e-01 98.8% 72.2%
4q66D01 6.20.120.50 Special › Other non-globular › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.75 41.0 4.38e-01 96.3% 61.6%
2awnC02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.75 41.0 4.27e-01 100.0% 57.7%
3go5A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.72 41.0 4.46e-01 100.0% 67.1%
2dyiA01 2.40.30.60 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › RimM 0.70 58.0 5.75e-01 100.0% 86.9%
1bkbA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.69 42.0 4.70e-01 100.0% 78.5%
4p02A03 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.68 58.0 5.06e-01 92.7% 76.2%
4l82A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.66 58.0 4.62e-01 95.1% 80.1%
1vw3C01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.66 60.0 5.09e-01 100.0% 68.7%
4azsA02 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.66 50.0 5.04e-01 80.5% 88.9%
2rdeA02 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.65 56.0 5.06e-01 93.9% 83.8%
2qckA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.65 57.0 4.60e-01 95.1% 82.1%
3bnkA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.65 56.0 4.30e-01 95.1% 75.3%
4xhyA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.65 56.0 4.48e-01 95.1% 77.0%
1uscA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.65 56.0 4.36e-01 95.1% 77.0%
2ecuA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.64 56.0 4.57e-01 95.1% 79.2%
1rz1A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.64 56.0 4.52e-01 95.1% 80.3%
1yoaA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.64 55.0 4.46e-01 95.1% 81.1%
2r0xA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.64 55.0 4.48e-01 95.1% 81.4%
1i0rA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.64 55.0 4.40e-01 95.1% 81.4%
3a5zD02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.63 38.0 4.26e-01 100.0% 78.1%
2d37A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.63 54.0 4.41e-01 95.1% 81.3%
3cb0D00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.63 54.0 4.33e-01 95.1% 79.5%
2r6vA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.63 54.0 4.31e-01 95.1% 84.8%
2nwaA01 2.40.240.20 Mainly Beta › Beta Barrel › Ribosomal Protein L25; Chain P › Hypothetical PUA domain-like; domain 1 0.63 49.0 5.16e-01 87.8% 92.0%
2e8yA01 2.60.40.2320 Mainly Beta › Sandwich › Immunoglobulin-like › 0.63 49.0 4.66e-01 95.1% 70.3%
3wdhA01 2.60.40.2320 Mainly Beta › Sandwich › Immunoglobulin-like › 0.63 51.0 4.86e-01 92.7% 76.0%
5tr9A01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.62 54.0 5.20e-01 98.8% 94.8%
5choF00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.62 53.0 4.30e-01 95.1% 80.6%
2eqsA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.62 43.0 4.17e-01 97.6% 65.2%
4f07E00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.62 53.0 4.36e-01 95.1% 80.5%
1ejeA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.62 53.0 4.05e-01 95.1% 74.0%
3nfwA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.62 53.0 4.16e-01 95.1% 70.9%
3bn3B01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 46.0 4.60e-01 93.9% 75.6%
3pftA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.61 52.0 4.21e-01 95.1% 80.1%
4feuF01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.60 43.0 4.57e-01 78.0% 84.9%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.60 46.0 4.00e-01 84.1% 56.9%
3qx3B03 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.59 49.0 4.61e-01 91.5% 78.0%
2r7rA04 3.30.70.2480 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 47.0 3.81e-01 86.6% 60.5%
3g2fA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.59 46.0 4.54e-01 84.1% 82.8%
4d9uA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.58 42.0 4.18e-01 80.5% 71.6%
3zn6A02 2.60.40.3410 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 49.0 4.88e-01 96.3% 96.6%
6ygnA02 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.58 43.0 3.93e-01 78.0% 59.3%
2weiA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.58 45.0 4.39e-01 84.1% 80.0%
2q83B01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.58 43.0 4.09e-01 80.5% 69.7%
3gniB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 45.0 4.42e-01 85.4% 84.3%
4c0tA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 45.0 4.34e-01 85.4% 81.5%
3zh8C01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 43.0 3.89e-01 80.5% 61.7%
4qjvA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.57 44.0 4.33e-01 93.9% 77.5%
3w1eA01 3.30.1660.40 Alpha Beta › 2-Layer Sandwich › Dodecin subunit-like › FlgT, N-terminal domain 0.57 39.0 3.87e-01 72.0% 97.8%
4aqcB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.56 42.0 4.07e-01 81.7% 76.0%
5d9hA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 41.0 4.02e-01 79.3% 76.1%
1a1xA00 2.40.15.10 Mainly Beta › Beta Barrel › Proto-oncogene - Oncogene Product P14tcl1 › TCL1/MTCP1 0.55 43.0 3.97e-01 85.4% 89.6%
2p5zX01 2.30.110.50 Mainly Beta › Roll › Pnp Oxidase; Chain A › 0.55 47.0 3.80e-01 97.6% 90.4%
2gy5A04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 45.0 4.31e-01 97.6% 77.8%
2y4iB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 42.0 4.09e-01 82.9% 74.7%
1kkeA02 2.60.90.20 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Virus attachment protein , globular domain 0.54 46.0 3.97e-01 100.0% 75.9%
3udfA03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 42.0 3.96e-01 100.0% 69.5%
4wtxA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 44.0 4.25e-01 96.3% 77.3%
3axsA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 46.0 3.08e-01 93.9% 45.0%
3rghA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 43.0 4.12e-01 96.3% 78.1%
1uxbA00 2.60.90.10 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Adenovirus pIV-related, attachment domain 0.53 44.0 3.51e-01 97.6% 73.9%
2c9aA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 43.0 4.18e-01 97.6% 81.4%
3f56A01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.52 44.0 4.13e-01 97.6% 92.5%
4m9pA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 42.0 3.99e-01 93.9% 74.0%
4kh9B02 2.60.40.1930 Mainly Beta › Sandwich › Immunoglobulin-like › Macroglobulin (MG2) domain 0.52 43.0 3.95e-01 93.9% 70.8%
4nzdB01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 43.0 4.13e-01 97.6% 78.8%
2mklC00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 43.0 4.00e-01 93.9% 79.0%
5lt5A02 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.52 42.0 4.02e-01 95.1% 90.2%
2rf4E02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.51 39.0 3.89e-01 96.3% 78.3%
2esrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 36.0 2.94e-01 85.4% 38.1%
5e4eC02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 42.0 4.04e-01 98.8% 78.2%
2pmwB02 2.60.120.690 Mainly Beta › Sandwich › Jelly Rolls › Proprotein convertase subtilisin/kexin type 9 0.50 37.0 2.88e-01 97.6% 31.7%
4ifdI02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.50 43.0 3.54e-01 97.6% 52.8%
7nitA06 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.50 43.0 3.47e-01 98.8% 49.4%
ECOD (71)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2323865 1.1.7.26 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › DNA_pol_B_3 0.97 89.0 8.99e-01 95.1% 95.1%
4987320 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.79 45.0 5.17e-01 100.0% 76.7%
4026004 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.77 70.0 6.24e-01 100.0% 93.9%
3586203 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.76 44.0 4.94e-01 98.8% 73.8%
3187444 1.1.7.81 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › SEN1_barrel 0.72 66.0 5.87e-01 100.0% 95.7%
163768 1.1.7.11 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.70 58.0 5.72e-01 100.0% 85.9%
3555622 1.1.7.21 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RIBIOP_C 0.70 57.0 5.89e-01 98.8% 96.0%
4642133 1.1.7.21 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RIBIOP_C 0.69 56.0 5.14e-01 100.0% 66.4%
3358216 1.1.7.21 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RIBIOP_C 0.69 56.0 5.10e-01 100.0% 66.4%
3611250 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.68 58.0 4.84e-01 95.1% 90.3%
4999166 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.67 56.0 5.87e-01 98.8% 100.0%
3786062 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.65 56.0 4.41e-01 95.1% 78.5%
164880 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.65 57.0 4.53e-01 95.1% 78.0%
3542635 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.65 57.0 4.86e-01 98.8% 65.9%
3264420 11.1.1.29 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › TIG 0.65 50.0 5.10e-01 95.1% 86.3%
4600482 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.64 56.0 4.43e-01 95.1% 75.8%
3742569 1.1.7.24 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_8 0.64 57.0 5.22e-01 100.0% 92.7%
3672433 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.64 56.0 3.83e-01 97.6% 33.8%
5051353 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.64 55.0 4.28e-01 95.1% 79.4%
3964364 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.64 55.0 4.38e-01 95.1% 79.4%
1560729 1.1.5.35 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › YwpF 0.64 51.0 4.27e-01 87.8% 63.9%
4974855 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.63 55.0 4.34e-01 95.1% 81.2%
5040562 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.63 53.0 5.17e-01 97.6% 83.3%
4955177 11.1.5.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.63 52.0 4.81e-01 98.8% 70.5%
4489896 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.63 54.0 4.21e-01 95.1% 70.6%
4322439 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.63 52.0 4.74e-01 97.6% 67.3%
4986653 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.63 53.0 4.18e-01 95.1% 78.8%
3744150 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.63 53.0 4.14e-01 95.1% 73.9%
5033350 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.63 52.0 4.09e-01 92.7% 75.3%
4348615 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.63 54.0 4.16e-01 95.1% 67.0%
5017812 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.62 53.0 4.09e-01 95.1% 75.8%
4563164 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.62 53.0 4.79e-01 97.6% 67.8%
3165720 1.1.7.13 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › TrmO 0.62 54.0 4.41e-01 98.8% 81.2%
3386803 1.1.7.79 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Beta-barrel_RND 0.62 55.0 5.20e-01 100.0% 95.0%
3251647 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.61 48.0 4.73e-01 97.6% 78.9%
5042801 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.61 44.0 3.76e-01 97.6% 47.7%
3600269 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.61 54.0 4.69e-01 97.6% 86.4%
3351405 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.60 51.0 3.38e-01 93.9% 38.3%
5017105 873.1.1.0 ↗ a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain 0.60 48.0 3.91e-01 87.8% 66.9%
4026122 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.60 51.0 3.38e-01 93.9% 41.2%
3614277 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.60 48.0 3.78e-01 93.9% 40.6%
5002657 12.1.1.114 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › DUF2341 0.60 49.0 4.93e-01 100.0% 89.4%
3709965 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.58 51.0 4.68e-01 100.0% 86.4%
4586058 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.57 50.0 4.66e-01 100.0% 79.0%
3298134 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.57 48.0 3.42e-01 93.9% 39.2%
3255120 206.1.1.72 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Pkinase_fungal 0.57 48.0 3.31e-01 93.9% 45.1%
3466694 11.1.5.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.56 46.0 3.87e-01 91.5% 98.6%
4024174 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.55 46.0 3.19e-01 93.9% 44.6%
3933157 11.1.1.1085 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › GBD_IRG7_N 0.55 42.0 3.97e-01 95.1% 68.0%
4264762 1.1.9.0 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain 0.55 45.0 3.17e-01 92.7% 72.8%
3991566 11.1.1.12 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Filamin 0.55 44.0 4.33e-01 93.9% 81.1%
3861216 11.1.1.3 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ig 0.55 46.0 4.33e-01 97.6% 78.0%
3937376 11.1.1.12 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Filamin 0.54 44.0 4.17e-01 97.6% 75.0%
4933727 305.1.1.1 ↗ a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L 0.54 45.0 4.38e-01 93.9% 82.2%
4024647 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.54 46.0 3.16e-01 95.1% 50.3%
4399143 11.1.1.3 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ig 0.54 45.0 4.26e-01 97.6% 77.0%
3912824 11.1.1.97 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set 0.54 46.0 4.39e-01 96.3% 82.1%
3557152 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 45.0 4.31e-01 96.3% 78.0%
3276970 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 47.0 4.28e-01 98.8% 80.9%
4293664 319.1.1.1 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.53 41.0 3.54e-01 85.4% 68.1%
1070873 11.1.1.299 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF4785_2nd 0.53 44.0 4.11e-01 93.9% 75.5%
3227068 11.1.1.1085 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › GBD_IRG7_N 0.53 42.0 3.94e-01 96.3% 71.0%
1144431 11.1.1.12 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Filamin 0.52 42.0 3.99e-01 93.9% 74.0%
5055979 304.39.1.1 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.52 39.0 3.81e-01 84.1% 82.1%
5054426 304.39.1.1 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.52 39.0 3.73e-01 84.1% 76.0%
5063878 12.3.1.8 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_65N 0.51 43.0 2.96e-01 93.9% 66.9%
3260607 11.1.1.12 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Filamin 0.51 44.0 3.97e-01 97.6% 75.7%
3625832 11.1.1.12 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Filamin 0.51 43.0 4.13e-01 97.6% 83.2%
3508361 11.1.1.12 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Filamin 0.51 42.0 4.00e-01 95.1% 77.0%
3991508 11.1.5.18 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › CP2 0.50 44.0 3.35e-01 97.6% 97.9%
1842935 11.1.5.57 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › Zona_CL2 0.50 43.0 3.52e-01 98.8% 61.2%
D3 high residues 540-568_680-826
PDB
Domain cluster: rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 121.5 6.00e-35 84.1% 26.3%
PF00136.27 DNA_pol_B 35.9 5.40e-09 18.2% 6.6%
D4 high residues 829-997
PDB
Domain cluster: rep: IMGVR_UViG_3300021255_003095-3300021255-Ga0223825_1010595139__D209-342
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 118.1 6.50e-34 93.5% 32.9%
D5 medium residues 1-33_122-159
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08452.17 best DNAP_B_exo_N 55.5 3.90e-15 31.0% 100.0%
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3iayA01 2.40.50.730 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.73 65.0 5.85e-01 100.0% 94.9%
4b08A01 2.40.50.730 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.69 60.0 5.80e-01 97.2% 96.3%
1jb7A02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.69 61.0 5.22e-01 100.0% 76.7%
3u4vA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.69 58.0 4.94e-01 93.0% 71.6%
8aa9A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.67 59.0 5.09e-01 100.0% 87.7%
1xjvA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 58.0 4.66e-01 100.0% 83.8%
1f9cA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.65 45.0 3.80e-01 71.8% 92.6%
4me3A02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.65 53.0 4.80e-01 90.1% 82.5%
6az1E03 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.65 39.0 3.92e-01 94.4% 58.3%
4e4fA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.64 44.0 3.56e-01 71.8% 79.4%
2gfaB01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.64 39.0 4.14e-01 90.1% 69.4%
3mkcA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.64 43.0 3.50e-01 70.4% 89.6%
3itwA02 3.30.720.110 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.63 33.0 3.62e-01 73.2% 60.7%
2eyqA05 2.40.10.170 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.63 43.0 4.61e-01 97.2% 84.7%
1h6hA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.63 43.0 3.47e-01 71.8% 87.4%
1b44D00 2.40.50.110 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.62 51.0 4.55e-01 93.0% 83.0%
2czoA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.62 42.0 3.51e-01 71.8% 93.1%
2vqeL00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.60 47.0 4.02e-01 88.7% 59.7%
4jn7A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.60 40.0 3.49e-01 70.4% 80.7%
3oajA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.59 41.0 3.21e-01 71.8% 67.4%
1f9qD00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.59 41.0 4.27e-01 93.0% 78.8%
1olzA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.58 39.0 2.38e-01 70.4% 41.5%
2l73A00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.57 40.0 3.24e-01 76.1% 85.3%
1x6oA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 47.0 4.59e-01 97.2% 96.2%
3b59A01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.54 40.0 3.42e-01 80.3% 92.6%
4lb0A02 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.54 47.0 3.61e-01 97.2% 95.1%
3sjnA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.53 41.0 3.52e-01 84.5% 89.1%
1iyxA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.53 40.0 3.41e-01 84.5% 76.0%
4tyzA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.53 37.0 3.29e-01 93.0% 48.6%
3n4eA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.53 41.0 3.66e-01 84.5% 87.5%
1h10A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.52 39.0 3.31e-01 97.2% 48.7%
3tw8A01 3.30.450.200 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin module 0.52 36.0 2.98e-01 74.6% 51.4%
3ecfA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 35.0 2.89e-01 71.8% 46.1%
3rriA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.51 36.0 3.00e-01 74.6% 87.8%
2aehA03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 40.0 3.53e-01 94.4% 56.8%
2re3A02 2.30.270.10 Mainly Beta › Roll › duf1285 protein fold › duf1285 protein 0.50 41.0 4.17e-01 93.0% 91.4%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4857803 2.1.1.40 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNAP_B_exo_N 0.82 40.0 5.31e-01 74.6% 91.9%
3811669 2.1.1.130 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.73 65.0 5.66e-01 100.0% 85.5%
4018347 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.73 65.0 5.89e-01 100.0% 86.3%
4001702 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.72 63.0 5.40e-01 98.6% 87.0%
3791987 2.1.1.25 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 0.71 63.0 5.39e-01 98.6% 87.8%
4972474 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.71 64.0 3.67e-01 100.0% 25.5%
3991931 2.1.1.130 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.70 62.0 5.22e-01 98.6% 78.3%
5063316 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.70 58.0 4.77e-01 91.5% 83.8%
3314558 2.1.1.130 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.70 62.0 4.97e-01 100.0% 65.3%
4026723 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.70 61.0 5.29e-01 97.2% 85.5%
3964458 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.70 56.0 5.21e-01 88.7% 81.1%
5025207 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.69 58.0 5.44e-01 91.5% 97.6%
3374948 2.1.1.130 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.69 61.0 5.45e-01 100.0% 94.0%
4213053 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.69 57.0 5.19e-01 91.5% 78.9%
3675935 2.1.1.223 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF28721 0.68 60.0 4.89e-01 100.0% 73.3%
4052370 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.68 54.0 5.59e-01 93.0% 95.4%
3657702 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.67 59.0 4.76e-01 100.0% 74.3%
5043745 2.1.1.287 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Zn_ribbon_TiaS 0.67 56.0 4.22e-01 94.4% 45.0%
5012820 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.66 53.0 4.88e-01 88.7% 68.4%
4092889 2.1.1.116 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Spt6_S1 0.65 52.0 4.56e-01 87.3% 77.1%
3742662 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.65 56.0 4.74e-01 98.6% 91.7%
143390 2.24.1.1 ↗ beta barrels › OB-fold › probable receptor YhhM › probable receptor YhhM › DUF2500 0.64 54.0 5.29e-01 93.0% 90.8%
3658019 2.1.1.285 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › CDC24_OB3, CDC24_OB2 0.64 53.0 3.52e-01 94.4% 27.7%
4578663 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.63 47.0 4.80e-01 78.9% 87.1%
3282644 2.24.1.2 ↗ beta barrels › OB-fold › probable receptor YhhM › probable receptor YhhM › DUF7489 0.62 49.0 5.08e-01 85.9% 92.3%
3424196 2.1.1.18 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › TRAM 0.62 51.0 4.82e-01 91.5% 87.1%
4819138 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 33.0 3.82e-01 76.1% 78.7%
4984315 218.1.1.2 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N 0.59 41.0 3.31e-01 73.2% 88.3%
3969377 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.57 43.0 4.30e-01 84.5% 83.8%
3358498 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.56 49.0 4.40e-01 100.0% 81.0%
3423400 220.1.1.8 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › GRAM 0.55 41.0 3.45e-01 94.4% 45.6%
4266498 218.1.1.1 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › MR_MLE_N 0.54 42.0 3.87e-01 85.9% 94.7%
1291499 218.1.1.1 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › MR_MLE_N 0.54 41.0 3.39e-01 85.9% 64.3%
3606892 218.1.1.0 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like 0.53 41.0 3.49e-01 85.9% 87.2%
139494 218.1.1.1 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › MR_MLE_N 0.53 41.0 3.55e-01 83.1% 80.4%
3203510 231.1.4.1 ↗ a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Apc (acetophenone carboxylase) beta subunit middle domain › Hydantoinase_B 0.53 37.0 2.96e-01 73.2% 64.3%
3711682 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.52 42.0 2.73e-01 90.1% 20.9%
3966949 243.3.1.3 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.52 35.0 3.25e-01 71.8% 54.4%
5082853 219.1.1.13 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.52 39.0 3.19e-01 80.3% 72.3%
3695460 247.1.1.23 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2+Lactamase_B_4 0.52 43.0 2.46e-01 91.5% 52.6%
3743426 247.1.1.31 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_4, Anti-Pycsar_Apyc1 0.50 42.0 2.45e-01 94.4% 50.3%
3268469 247.1.1.23 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2+Lactamase_B_4 0.50 41.0 2.38e-01 91.5% 37.3%
D6 medium residues 34-121
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7c51A01 3.30.70.2970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein of unknown function (DUF541), domain 2 0.58 47.0 4.37e-01 88.6% 100.0%
4hvzA02 3.30.70.2970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein of unknown function (DUF541), domain 2 0.58 48.0 4.49e-01 95.5% 100.0%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 47.0 4.46e-01 95.5% 87.9%
1nbwA02 3.90.470.30 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Coenzyme B12-Dependent Enzyme linker domain 0.54 37.0 3.17e-01 70.5% 96.5%
5mmjj00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.54 42.0 4.10e-01 87.5% 100.0%
5xyiU00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.54 42.0 4.12e-01 85.2% 100.0%
1b3tA00 3.30.70.390 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Epstein Barr virus nuclear antigen-1, DNA-binding domain 0.52 43.0 3.76e-01 95.5% 73.5%
5k8mA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 41.0 3.64e-01 86.4% 98.5%
2ebeA00 3.30.70.2290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein of unknown function (DUF3208) 0.52 40.0 3.84e-01 85.2% 95.3%
2xzmJ00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.51 42.0 4.06e-01 95.5% 99.0%
2wyhA05 2.60.40.2210 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 40.0 3.55e-01 86.4% 77.6%
1yb2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 34.0 2.60e-01 70.5% 82.6%
5hfjC00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.50 38.0 3.07e-01 86.4% 79.4%
6tmfM00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.50 42.0 4.05e-01 97.7% 99.0%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3089541 304.114.1.0 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.89 69.0 7.60e-01 84.1% 100.0%
3497298 304.47.1.0 ↗ a+b two layers › Alpha-beta plaits › SEA domain › SEA domain 0.60 45.0 3.96e-01 81.8% 97.1%
3790670 304.44.1.1 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 0.59 50.0 4.29e-01 96.6% 72.0%
3401330 304.44.1.1 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 0.58 49.0 4.49e-01 96.6% 89.2%
3953553 304.133.1.1 ↗ a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.58 45.0 4.36e-01 87.5% 100.0%
5041672 304.44.1.1 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 0.58 46.0 4.39e-01 87.5% 100.0%
4994692 304.44.1.1 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 0.56 46.0 4.32e-01 92.0% 94.5%
3701305 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.56 49.0 4.10e-01 100.0% 89.4%
3996979 273.1.1.0 ↗ a+b three layers › PR-1-like › PR-1-like › PR-1-like 0.56 39.0 3.10e-01 71.6% 67.9%
4951176 304.133.1.1 ↗ a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.56 45.0 4.05e-01 90.9% 83.1%
3499602 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.56 44.0 4.24e-01 87.5% 88.0%
3839279 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.55 48.0 4.61e-01 100.0% 100.0%
4182477 304.109.1.1 ↗ a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e › Ribosomal_L23 0.55 40.0 3.86e-01 76.1% 72.0%
4997602 242.1.1.0 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.55 41.0 3.90e-01 79.5% 74.3%
3217666 220.1.1.66 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › SOS1_NGEF_PH 0.55 44.0 3.80e-01 87.5% 99.3%
4927440 304.133.1.1 ↗ a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.54 40.0 3.95e-01 83.0% 98.0%
5052711 304.55.2.0 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.54 43.0 3.82e-01 92.0% 95.7%
5067499 1.1.8.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain 0.54 41.0 3.69e-01 84.1% 73.8%
4584621 304.44.1.1 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 0.54 41.0 4.05e-01 87.5% 98.0%
3463183 304.25.1.0 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.53 43.0 3.95e-01 90.9% 100.0%
5050142 304.25.1.0 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.53 44.0 3.89e-01 96.6% 97.9%
4992378 304.133.1.1 ↗ a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.53 46.0 4.20e-01 100.0% 98.3%
3686505 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 45.0 3.38e-01 100.0% 89.0%
3703392 304.107.1.0 ↗ a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain 0.53 47.0 3.31e-01 100.0% 77.1%
3721452 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 44.0 3.35e-01 100.0% 89.8%
3821846 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.52 43.0 4.07e-01 95.5% 91.8%
4943323 304.44.1.0 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 0.52 43.0 4.19e-01 97.7% 98.1%
3667518 328.1.1.1 ↗ a+b two layers › IF3-like › AlbA-like › AlbA-like › Alba 0.52 39.0 3.76e-01 96.6% 69.5%
1505358 304.51.1.7 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR_Cas6 0.51 41.0 3.47e-01 92.0% 92.1%
5009941 304.51.1.7 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR_Cas6 0.51 39.0 3.34e-01 86.4% 95.6%
3665347 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.51 42.0 4.03e-01 95.5% 93.3%
3964535 310.3.1.1 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related › PilO 0.51 39.0 3.62e-01 84.1% 73.9%
3804095 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.50 35.0 2.95e-01 72.7% 75.5%
1438039 304.44.1.1 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › Ribosomal_S10 0.50 39.0 3.56e-01 88.6% 81.2%
3740338 11.1.1.915 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF26111 0.50 38.0 3.43e-01 84.1% 80.0%
D7 medium residues 612-671
PDB
Domain cluster: rep: hypothetical_protein_FR483_N023L__YP_001425655__Paramecium_bursaria_Chlorella_virus_FR483__399781__D557-623
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 70.5 1.80e-19 98.3% 12.4%