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DNA_polymerase_B

Euk-Vir

Drosophila_innubila_nudivirus

DNA_polymerase_B__YP_009553129__Drosophila_innubila_nudivirus__2057187

Identity

Accession:
YP_009553129 ↗
Protein ID:
DNA_polymerase_B
Kingdom:
euk

Quality

50.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 260-512
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03104.26 best DNA_pol_B_exo1 34.6 1.90e-08 66.8% 73.1%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1d5aA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.86 69.0 7.49e-01 100.0% 95.9%
1s5jA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.85 64.0 7.30e-01 90.9% 99.5%
2gv9A03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.83 71.0 7.60e-01 92.5% 99.5%
3iayA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 65.0 7.13e-01 92.5% 98.6%
4qclA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.79 72.0 7.05e-01 100.0% 87.5%
1noyB02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.79 68.0 7.27e-01 93.3% 99.6%
4fvmA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.75 67.0 6.97e-01 92.5% 98.3%
1ewqA02 3.30.420.110 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › MutS, connector domain 0.72 30.0 4.47e-01 93.7% 84.7%
3mwpB02 3.30.420.410 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Arenaviral nucleoprotein, C-terminal domain 0.62 38.0 4.63e-01 92.1% 90.2%
4nzpA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 31.0 4.03e-01 82.2% 97.8%
4tkzA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.55 27.0 3.55e-01 94.9% 84.6%
2z5bB01 3.30.230.90 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.54 27.0 3.86e-01 89.7% 99.2%
1v7wA02 2.60.420.10 Mainly Beta › Sandwich › Maltose phosphorylase, domain 3 › Maltose phosphorylase, domain 3 0.53 19.0 3.16e-01 87.0% 91.7%
1ml8A02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.53 21.0 3.44e-01 75.9% 96.9%
3bypA00 3.30.70.1350 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain 0.52 19.0 3.23e-01 76.3% 98.8%
3lucA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 27.0 3.68e-01 79.8% 100.0%
ECOD (67)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4933243 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.90 61.0 7.33e-01 98.8% 98.3%
4931271 2484.1.1.68 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.90 60.0 6.62e-01 95.3% 81.4%
5017082 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.88 70.0 6.08e-01 100.0% 57.5%
3266685 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.88 75.0 4.68e-01 100.0% 19.1%
5056578 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.88 72.0 6.79e-01 100.0% 72.2%
4953654 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.87 73.0 6.42e-01 100.0% 62.9%
4934764 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.87 74.0 6.34e-01 100.0% 59.7%
4988803 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.87 72.0 5.99e-01 100.0% 53.7%
4972474 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.87 75.0 5.25e-01 100.0% 32.9%
4452101 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.87 70.0 7.55e-01 100.0% 94.5%
4282509 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.87 70.0 5.18e-01 100.0% 36.8%
2801086 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.87 70.0 6.06e-01 100.0% 57.8%
5027090 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.85 72.0 7.36e-01 100.0% 89.0%
4502019 2484.1.1.197 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 0.85 70.0 5.78e-01 100.0% 51.3%
4218318 2484.1.1.295 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, RNase_H_2 0.85 72.0 6.58e-01 100.0% 68.8%
5076614 2484.1.1.328 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B 0.85 73.0 5.21e-01 100.0% 35.2%
4972218 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 73.0 5.59e-01 100.0% 44.4%
4948574 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.85 72.0 5.99e-01 100.0% 55.0%
4983222 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.85 72.0 6.26e-01 100.0% 61.4%
5025208 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.84 66.0 6.92e-01 100.0% 87.4%
5019480 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.84 73.0 5.03e-01 100.0% 31.0%
5081878 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.84 64.0 5.57e-01 100.0% 54.7%
5005285 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.84 73.0 7.61e-01 100.0% 96.2%
4981192 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.83 66.0 6.58e-01 100.0% 79.6%
5023018 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.83 66.0 7.25e-01 91.3% 97.6%
1822623 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.83 76.0 7.40e-01 100.0% 87.6%
5069333 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.83 64.0 5.50e-01 100.0% 53.6%
3932596 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.81 73.0 7.57e-01 100.0% 98.7%
3368695 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.81 74.0 6.19e-01 100.0% 60.3%
3606428 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.81 73.0 7.55e-01 99.6% 99.1%
None 0.81 74.0 5.26e-01 100.0% 37.0%
4022366 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.81 73.0 5.23e-01 100.0% 36.9%
None 0.81 74.0 5.24e-01 100.0% 36.7%
4891100 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.81 70.0 6.88e-01 98.8% 83.6%
3705562 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 74.0 5.23e-01 100.0% 36.0%
3558197 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.81 73.0 7.48e-01 99.6% 95.5%
3628202 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 74.0 5.19e-01 100.0% 35.5%
3496492 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.81 75.0 7.15e-01 100.0% 84.5%
3710418 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.81 73.0 6.26e-01 100.0% 63.2%
None 0.80 73.0 6.31e-01 100.0% 64.9%
4874454 2.1.1.25 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 0.80 72.0 7.11e-01 100.0% 88.3%
1790898 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.80 72.0 7.02e-01 100.0% 86.3%
3214818 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.80 71.0 6.07e-01 100.0% 61.9%
4957483 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.79 60.0 6.79e-01 96.8% 98.0%
3825992 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.79 73.0 7.41e-01 100.0% 96.8%
3797773 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.79 74.0 6.97e-01 100.0% 83.1%
3784398 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.79 74.0 7.46e-01 100.0% 96.9%
3192875 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.79 71.0 5.55e-01 100.0% 48.9%
3794217 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.78 74.0 5.57e-01 100.0% 46.4%
3168836 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.78 74.0 7.44e-01 100.0% 97.6%
4944521 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.78 62.0 6.83e-01 91.7% 97.6%
3404726 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.78 74.0 6.93e-01 100.0% 83.7%
11143 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.78 74.0 6.31e-01 100.0% 66.4%
4323378 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.77 73.0 6.90e-01 100.0% 85.5%
4023334 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.77 73.0 7.03e-01 100.0% 89.3%
3684974 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.76 73.0 5.21e-01 100.0% 38.2%
3492151 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.76 73.0 6.55e-01 100.0% 83.0%
3206356 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.76 73.0 6.08e-01 100.0% 63.0%
3682165 2484.1.1.153 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1744 0.75 50.0 5.93e-01 100.0% 94.4%
3466667 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.75 72.0 5.16e-01 100.0% 40.0%
2958185 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.74 71.0 6.79e-01 100.0% 89.7%
4958553 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.72 60.0 6.52e-01 94.9% 99.1%
3369280 2484.1.1.153 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1744 0.71 46.0 3.88e-01 100.0% 39.5%
3917161 2484.1.1.153 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1744 0.67 46.0 4.00e-01 100.0% 45.5%
3219651 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 54.0 4.97e-01 99.6% 95.2%
5078856 327.7.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like 0.53 20.0 3.38e-01 77.9% 97.8%
3971737 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.51 33.0 3.16e-01 98.0% 55.2%
D2 high residues 1210-1254_1309-1374
PDB
D3 medium residues 11-30_83-118
PDB
D4 medium residues 119-256_517-542_679-705
PDB
D5 medium residues 657-678_706-760
PDB
D6 medium residues 761-805_1041-1116
PDB
D7 medium residues 1117-1209
PDB