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DNA_polymerase

Euk-Vir

Fowl_aviadenovirus_C

DNA_polymerase__YP_004346921__Fowl_aviadenovirus_C__190063

Identity

Accession:
YP_004346921 ↗
Protein ID:
DNA_polymerase
Kingdom:
euk

Quality

80.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 18-24_49-164
PDB
D2 medium residues 215-458
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03175.19 best DNA_pol_B_2 40.0 3.30e-10 30.7% 16.2%
D3 medium residues 459-562
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03175.19 best DNA_pol_B_2 81.1 1.10e-22 100.0% 20.1%
D4 medium residues 563-591_610-633_655-692_771-808
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF03175.19 best DNA_pol_B_2 31.2 1.60e-07 42.6% 9.0%
PF03175.19 DNA_pol_B_2 43.1 3.90e-11 30.2% 8.3%
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1li5A02 1.20.120.640 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.66 31.0 3.70e-01 98.4% 64.4%
4x5mA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.64 30.0 3.68e-01 100.0% 68.6%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.64 30.0 3.75e-01 100.0% 71.1%
5bylA02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.62 32.0 2.71e-01 91.5% 31.8%
1yvwA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.61 30.0 3.54e-01 98.4% 67.4%
1nlxA00 1.20.120.320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen 0.59 28.0 3.13e-01 93.0% 52.9%
4tq1A03 1.10.246.190 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Autophagy protein Apg5, helix rich domain 0.53 24.0 3.61e-01 71.3% 98.3%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3394485 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.67 33.0 4.11e-01 99.2% 74.1%
5072726 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.64 30.0 3.77e-01 95.3% 73.3%
1411677 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.64 30.0 3.75e-01 100.0% 71.1%
3938825 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.63 31.0 3.86e-01 99.2% 72.9%
5013782 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.63 29.0 3.83e-01 100.0% 77.3%
5029393 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.63 31.0 3.73e-01 100.0% 69.7%
3491658 5000.3.1.1 alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 0.60 29.0 2.70e-01 97.7% 33.9%
3602005 650.1.1.0 alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain 0.58 35.0 4.36e-01 98.4% 96.2%
D5 medium residues 634-654_980-1059
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ungC03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.64 45.0 4.14e-01 81.2% 56.4%
3dgpB00 3.30.70.1220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TFB5-like 0.63 39.0 4.60e-01 92.1% 98.4%
1x9mA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 53.0 4.38e-01 96.0% 83.1%
1ydlA00 3.30.70.1220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TFB5-like 0.60 33.0 3.84e-01 72.3% 74.6%
2uvaG03 3.30.70.3320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 44.0 4.32e-01 87.1% 72.2%
3i4hX01 3.30.70.1890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 44.0 4.13e-01 84.2% 89.8%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 38.0 3.86e-01 80.2% 69.9%
1gmnA01 3.50.4.10 Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor 0.54 31.0 3.28e-01 70.3% 62.5%
6nqbF00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.54 35.0 3.86e-01 81.2% 84.4%
2khdA00 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 42.0 4.17e-01 92.1% 79.6%
5ja2A01 3.30.559.30 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Nonribosomal peptide synthetase, condensation domain 0.54 43.0 3.30e-01 90.1% 80.1%
2jzxA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.52 38.0 4.13e-01 91.1% 97.5%
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 38.0 4.07e-01 79.2% 92.9%
1ufwA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.52 37.0 3.86e-01 76.2% 82.1%
5k9fA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 39.0 3.89e-01 82.2% 83.5%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4956224 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.72 59.0 4.38e-01 86.1% 78.3%
3690781 304.48.1.11 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RNA_pol 0.60 46.0 4.74e-01 89.1% 86.3%
4026401 878.1.1.7 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Pro_sub2 0.58 45.0 4.53e-01 83.2% 81.9%
5075512 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.58 45.0 3.72e-01 85.1% 69.3%
4030214 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.58 47.0 4.10e-01 89.1% 92.3%
3170679 304.9.1.10 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Calcipressin 0.57 42.0 4.15e-01 79.2% 71.8%
3595281 3715.1.1.0 a+b two layers › Ribosomal protein L22e › Ribosomal protein L22e › Ribosomal protein L22e 0.56 43.0 4.09e-01 81.2% 86.7%
3601834 304.48.1.6 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.56 46.0 4.49e-01 90.1% 81.8%
4311880 304.11.1.4 a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › FAS_AT_central 0.53 43.0 4.34e-01 90.1% 91.4%
3185440 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.52 42.0 3.26e-01 87.1% 89.6%
3707104 878.1.1.3 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › FAZ1_cons 0.52 43.0 4.33e-01 90.1% 95.0%
4990817 301.2.1.1 a+b three layers › Bacillus chorismate mutase-like › PurM N-terminal domain-like › PurM N-terminal domain-like › AIRS 0.51 35.0 3.21e-01 72.3% 93.6%
3740867 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.51 38.0 4.06e-01 82.2% 96.5%
3256533 2004.1.1.17 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Myosin_head 0.51 37.0 2.27e-01 79.2% 74.5%
D6 medium residues 693-770
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03175.19 best DNA_pol_B_2 66.7 2.70e-18 100.0% 15.2%
D7 medium residues 809-862_955-979
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03175.19 best DNA_pol_B_2 26.1 5.40e-06 98.7% 11.3%
D8 medium residues 1060-1206
PDB
Domain cluster: representative
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4076295 375.1.1.88 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Ogr_Delta 0.62 25.0 4.03e-01 94.6% 100.0%