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DNA_polymerase
Euk-VirGoose_adenovirus_4
DNA_polymerase__YP_006383556__Goose_adenovirus_4__1193422
Identity
- Accession:
- YP_006383556 ↗
- Protein ID:
- DNA_polymerase
- Kingdom:
- euk
Quality
77.3
mean pLDDT
Taxonomy
Bamfordvirae›
Preplasmiviricota›
Pharingeaviricetes›
Rowavirales›
Adenoviridae›
Aviadenovirus›
Goose_adenovirus_4
TaxID: 1193422
Cluster
View cluster (24 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 69-195
Domain cluster:
rep: DNA_polymerase__YP_009246380__Bat_mastadenovirus_WIV10__1788432__D69-178
D2
medium
residues 238-341_390-432
D3
medium
residues 635-653_687-794
Domain cluster:
rep: DNA_polymerase__NP_040516__Human_mastadenovirus_C__129951__D703-805
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03175.19 best | DNA_pol_B_2 | 77.1 | 1.90e-21 | 85.0% | 20.3% |
D4
medium
residues 795-832_972-993
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03175.19 best | DNA_pol_B_2 | 47.9 | 1.30e-12 | 95.0% | 8.1% |
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3gonA02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.84 | 58.0 | 4.31e-01 | 98.3% | 32.1% |
| 6he1B01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.83 | 54.0 | 5.29e-01 | 96.7% | 62.5% |
| 1yzmA00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.83 | 57.0 | 6.42e-01 | 100.0% | 93.5% |
| 4u1cA01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.82 | 55.0 | 5.91e-01 | 96.7% | 80.8% |
| 4ebjA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.81 | 56.0 | 4.24e-01 | 100.0% | 33.1% |
| 3k59A06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.80 | 59.0 | 6.57e-01 | 91.7% | 100.0% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.78 | 57.0 | 4.87e-01 | 100.0% | 50.0% |
| 3etuA01 | 1.10.287.3290 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.77 | 54.0 | 5.31e-01 | 100.0% | 67.7% |
| 4b6xA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 56.0 | 5.36e-01 | 100.0% | 66.7% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.75 | 57.0 | 4.39e-01 | 100.0% | 38.7% |
| 3craB01 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.74 | 55.0 | 4.82e-01 | 100.0% | 54.7% |
| 2yxhA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.71 | 55.0 | 4.42e-01 | 100.0% | 44.2% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.70 | 57.0 | 4.99e-01 | 100.0% | 61.2% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.69 | 57.0 | 4.48e-01 | 100.0% | 44.6% |
| 5t1dB00 | 3.10.390.20 | Alpha Beta › Roll › SAND domain › Viral glycoprotein L | 0.63 | 42.0 | 3.62e-01 | 100.0% | 41.4% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.62 | 46.0 | 4.63e-01 | 91.7% | 81.4% |
| 3aagA01 | 3.40.1380.40 | Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › | 0.55 | 35.0 | 2.77e-01 | 86.7% | 26.6% |
| 3fedA03 | 1.20.930.40 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Transferrin receptor-like, dimerisation domain | 0.53 | 44.0 | 3.38e-01 | 100.0% | 44.5% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3369096 | 4970.1.1.3 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B_2 | 0.95 | 61.0 | 7.08e-01 | 96.7% | 88.9% |
| 4193 | 4970.1.1.0 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I | 0.89 | 58.0 | 6.73e-01 | 96.7% | 93.0% |
| 4682578 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.85 | 58.0 | 3.82e-01 | 100.0% | 20.0% |
| 4472442 | 192.11.1.1 ↗ | alpha bundles › Long alpha-hairpin › C-terminal UvrC-binding domain of UvrB › C-terminal UvrC-binding domain of UvrB › UVR | 0.85 | 55.0 | 6.62e-01 | 98.3% | 100.0% |
| 3976258 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.83 | 58.0 | 6.04e-01 | 100.0% | 78.2% |
| 3967220 | 632.11.1.13 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › PF27144 | 0.81 | 55.0 | 5.37e-01 | 100.0% | 65.6% |
| 3902516 | 109.4.1.1448 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_7, TPR_10, TPR_12, TPR_MalT | 0.81 | 54.0 | 3.43e-01 | 98.3% | 15.8% |
| 3174429 | 192.17.1.0 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like | 0.81 | 58.0 | 6.61e-01 | 100.0% | 100.0% |
| 3504819 | 192.17.1.6 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › CC2D1A-B_DM14 | 0.80 | 58.0 | 5.66e-01 | 100.0% | 70.8% |
| 3513338 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.80 | 53.0 | 3.55e-01 | 100.0% | 18.7% |
| 3573745 | 609.1.1.0 ↗ | alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase | 0.79 | 57.0 | 4.00e-01 | 100.0% | 26.5% |
| 3615115 | 109.4.1.192 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 | 0.79 | 56.0 | 3.73e-01 | 100.0% | 20.2% |
| 3774145 | 192.17.1.6 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › CC2D1A-B_DM14 | 0.77 | 56.0 | 4.24e-01 | 100.0% | 34.1% |
| 4565034 | 159.1.3.3 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › putative NTP pyrophosphohydrolase Exig_1061 › MazG | 0.77 | 56.0 | 4.30e-01 | 100.0% | 36.8% |
| 3881336 | 109.4.1.2896 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, GoLoco, TPR_7, TPR_8, TPR_12 | 0.76 | 58.0 | 3.71e-01 | 80.0% | 89.8% |
| 3725040 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.75 | 55.0 | 3.62e-01 | 100.0% | 20.4% |
| 3707335 | 192.17.1.0 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like | 0.75 | 53.0 | 4.93e-01 | 100.0% | 60.0% |
| 3968795 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.74 | 69.0 | 4.36e-01 | 100.0% | 31.5% |
| 3943776 | 159.1.1.1 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG | 0.71 | 55.0 | 4.23e-01 | 100.0% | 38.5% |
| 3639102 | 109.4.1.1129 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TRAPPC9-Trs120 | 0.70 | 57.0 | 4.36e-01 | 100.0% | 41.6% |
| 5032400 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.69 | 56.0 | 4.08e-01 | 90.0% | 80.0% |
| 4995146 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.67 | 62.0 | 5.34e-01 | 100.0% | 72.2% |
| 3755359 | 109.4.1.198 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 | 0.65 | 55.0 | 3.78e-01 | 90.0% | 76.8% |
| 4541925 | 5000.4.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain | 0.63 | 56.0 | 3.76e-01 | 100.0% | 41.8% |
| 3552824 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.60 | 56.0 | 3.66e-01 | 100.0% | 77.3% |
| 3596878 | 109.40.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA polymerase alpha-binding protein Ctf4 C-terminal domain › DNA polymerase alpha-binding protein Ctf4 C-terminal domain | 0.60 | 54.0 | 4.16e-01 | 100.0% | 70.0% |
| 3371182 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.59 | 54.0 | 4.43e-01 | 100.0% | 57.1% |
D5
medium
residues 1120-1209
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6wcsA02 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.53 | 34.0 | 2.65e-01 | 74.4% | 28.8% |
| 2np2A00 | 4.10.520.10 | Few Secondary Structures › Irregular › HU Protein; Chain A › IHF-like DNA-binding proteins | 0.52 | 32.0 | 3.12e-01 | 90.0% | 52.9% |
| 6lpwA02 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.51 | 33.0 | 2.58e-01 | 74.4% | 28.3% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3621341 | 382.1.1.0 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like | 0.53 | 34.0 | 3.71e-01 | 76.7% | 78.7% |
| 4855693 | 323.1.1.5 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Condensation | 0.53 | 30.0 | 2.64e-01 | 74.4% | 34.7% |
| 3957478 | 323.1.1.11 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › PapA_C | 0.52 | 32.0 | 2.73e-01 | 74.4% | 35.6% |