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DNA_polymerase
Euk-VirLizard_adenovirus_2
DNA_polymerase__YP_009051654__Lizard_adenovirus_2__874272
Identity
- Accession:
- YP_009051654 ↗
- Protein ID:
- DNA_polymerase
- Kingdom:
- euk
Quality
76.7
mean pLDDT
Taxonomy
Bamfordvirae›
Preplasmiviricota›
Pharingeaviricetes›
Rowavirales›
Adenoviridae›
Barthadenovirus›
Lizard_adenovirus_2
TaxID: 874272
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 13-132
Domain cluster:
rep: DNA_polymerase__YP_009246380__Bat_mastadenovirus_WIV10__1788432__D69-178
D2
medium
residues 160-262
Domain cluster:
rep: MZ727332.1__UCW44374.1__X__00007__D7-96
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1hi9A02 | 3.30.1360.130 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Dipeptide transport protein | 0.67 | 46.0 | 5.25e-01 | 82.5% | 97.4% |
| 3f6tA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.64 | 45.0 | 4.01e-01 | 72.8% | 77.7% |
| 1ir6A02 | 3.10.310.30 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › | 0.64 | 41.0 | 3.85e-01 | 78.6% | 51.9% |
| 4fvmA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.60 | 45.0 | 3.44e-01 | 78.6% | 55.1% |
| 4mgrA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.60 | 41.0 | 2.83e-01 | 70.9% | 80.2% |
| 1js3A03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.59 | 44.0 | 4.54e-01 | 78.6% | 82.5% |
| 1gt7A00 | 3.40.225.10 | Alpha Beta › 3-Layer(aba) Sandwich › L-fuculose-1-phosphate Aldolase › Class II aldolase/adducin N-terminal domain | 0.59 | 45.0 | 3.36e-01 | 82.5% | 80.7% |
| 4q6rA02 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.58 | 41.0 | 3.78e-01 | 79.6% | 57.3% |
| 2qgyB01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.58 | 37.0 | 3.39e-01 | 83.5% | 48.9% |
| 3ftbA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.57 | 40.0 | 3.93e-01 | 78.6% | 67.0% |
| 4w8iA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.57 | 40.0 | 3.87e-01 | 84.5% | 63.6% |
| 1rp0A02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.57 | 43.0 | 3.28e-01 | 79.6% | 100.0% |
| 3nuiA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.55 | 44.0 | 3.92e-01 | 86.4% | 60.3% |
| 3devA02 | 3.10.310.30 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › | 0.55 | 44.0 | 4.30e-01 | 87.4% | 87.1% |
| 2yqrA01 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.55 | 41.0 | 4.13e-01 | 79.6% | 99.0% |
| 7l9pK01 | 3.30.900.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain | 0.54 | 33.0 | 3.16e-01 | 88.3% | 51.3% |
| 4qclA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.53 | 43.0 | 3.20e-01 | 87.4% | 81.9% |
| 3ga8A00 | 3.10.20.860 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.53 | 32.0 | 3.93e-01 | 78.6% | 95.5% |
| 1jpdX01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.52 | 33.0 | 3.37e-01 | 82.5% | 65.7% |
| 3ugvA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.52 | 35.0 | 3.31e-01 | 82.5% | 57.1% |
| 5dk5A01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.51 | 36.0 | 2.91e-01 | 72.8% | 93.5% |
| 2omdA00 | 3.90.1170.40 | Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Molybdopterin biosynthesis MoaE subunit | 0.51 | 40.0 | 3.64e-01 | 82.5% | 88.9% |
| 4e98C00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 36.0 | 3.65e-01 | 74.8% | 75.2% |
| 1wljA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.50 | 39.0 | 3.38e-01 | 84.5% | 95.2% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5000684 | 5104.1.1.0 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases | 0.67 | 46.0 | 4.37e-01 | 83.5% | 60.0% |
| 5082143 | 304.26.1.1 ↗ | a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP | 0.67 | 44.0 | 4.45e-01 | 70.9% | 65.7% |
| 4269197 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.67 | 48.0 | 5.32e-01 | 87.4% | 96.2% |
| 4563340 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.63 | 40.0 | 4.68e-01 | 77.7% | 94.3% |
| 3597964 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.62 | 47.0 | 3.28e-01 | 79.6% | 32.5% |
| 3702504 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.61 | 47.0 | 3.33e-01 | 79.6% | 33.6% |
| 3492151 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.61 | 47.0 | 3.26e-01 | 80.6% | 33.9% |
| 3167764 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.61 | 47.0 | 3.34e-01 | 80.6% | 33.1% |
| 3193111 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.60 | 46.0 | 3.11e-01 | 80.6% | 36.6% |
| 4025970 | 306.3.1.2 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › Img2 | 0.57 | 39.0 | 4.18e-01 | 79.6% | 82.2% |
| 2958185 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.56 | 44.0 | 3.24e-01 | 84.5% | 36.7% |
| 3262323 | 220.1.1.21 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › SPT16 | 0.56 | 36.0 | 3.27e-01 | 78.6% | 49.6% |
| 4534145 | 3016.1.1.11 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › SelA | 0.55 | 39.0 | 3.90e-01 | 74.8% | 75.5% |
| 4956984 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.55 | 43.0 | 4.30e-01 | 83.5% | 88.6% |
| 4300310 | 3016.1.1.11 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › SelA | 0.55 | 39.0 | 3.92e-01 | 73.8% | 77.9% |
| 5038038 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.54 | 42.0 | 4.11e-01 | 83.5% | 83.5% |
| 1790898 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.53 | 43.0 | 3.19e-01 | 86.4% | 80.4% |
| 4874454 | 2.1.1.25 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 | 0.53 | 43.0 | 3.20e-01 | 86.4% | 82.3% |
| 4378664 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.52 | 43.0 | 3.23e-01 | 90.3% | 84.6% |
| 3717787 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.52 | 44.0 | 2.96e-01 | 93.2% | 93.1% |
| 3937813 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.52 | 41.0 | 3.00e-01 | 84.5% | 60.4% |
| 5077865 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.51 | 42.0 | 3.89e-01 | 88.3% | 78.5% |
| 3256029 | 218.1.1.0 ↗ | a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like | 0.51 | 42.0 | 3.69e-01 | 94.2% | 59.4% |
D3
medium
residues 523-541_572-718_844-865
Domain cluster:
rep: DNA_polymerase__YP_002213831__Human_mastadenovirus_B__108098__D647-666_688-846_965-977
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03175.19 best | DNA_pol_B_2 | 143.9 | 1.00e-41 | 84.6% | 29.3% |