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DNA_polymerase

Euk-Vir

Penaeus_monodon_nudivirus

DNA_polymerase__YP_009051843__Penaeus_monodon_nudivirus__1529056

Identity

Accession:
YP_009051843 ↗
Protein ID:
DNA_polymerase
Kingdom:
euk

Quality

73.4 mean pLDDT

Taxonomy

Naldaviricetes› Lefavirales› Nudiviridae› Gammanudivirus› Penaeus_monodon_nudivirus

TaxID: 1529056

Cluster

View cluster (158 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 55-184_453-476
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ghpA03 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 35.0 4.64e-01 70.1% 100.0%
2cq4A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 40.0 4.90e-01 79.9% 99.0%
2cqiA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 38.0 4.50e-01 86.4% 89.3%
2cjkA02 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 34.0 4.44e-01 70.8% 100.0%
1whwA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 35.0 4.33e-01 77.9% 90.4%
3mgjA00 3.30.70.2690 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › LOR/SDH bifunctional enzyme, conserved domain 0.61 35.0 4.37e-01 70.1% 90.6%
2mgzA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 35.0 4.22e-01 77.3% 88.3%
3im8A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.61 31.0 4.11e-01 70.8% 98.6%
1sjrA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.60 35.0 4.10e-01 70.8% 81.5%
3smzA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 36.0 4.11e-01 96.1% 81.2%
3smzA03 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 36.0 4.44e-01 94.2% 97.9%
3v4mB00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.54 35.0 4.16e-01 92.2% 97.1%
2ia0B02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.51 30.0 3.55e-01 71.4% 86.9%
3gz7B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 32.0 3.81e-01 79.2% 100.0%
ECOD (48)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3715105 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.70 36.0 4.79e-01 90.9% 90.6%
3784435 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.66 36.0 4.65e-01 77.9% 95.3%
4026044 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.66 39.0 4.77e-01 99.4% 91.0%
3782130 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.65 37.0 4.79e-01 74.7% 100.0%
3584856 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.65 40.0 4.64e-01 79.9% 85.5%
3224221 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.65 37.0 4.46e-01 77.3% 85.0%
3471767 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.65 40.0 5.02e-01 79.9% 100.0%
4181072 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.65 38.0 4.76e-01 92.9% 94.7%
3919443 304.9.1.11 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Nup35_RRM 0.64 35.0 4.00e-01 71.4% 69.6%
4098438 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.64 40.0 4.88e-01 71.4% 96.0%
3307669 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.64 39.0 4.79e-01 97.4% 96.8%
3995117 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.63 38.0 4.71e-01 81.8% 96.8%
3806596 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.63 37.0 4.72e-01 90.9% 100.0%
4552457 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.63 37.0 4.64e-01 81.2% 98.9%
3887318 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.63 39.0 4.36e-01 95.5% 79.2%
3600599 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.62 37.0 4.06e-01 72.7% 71.2%
3475933 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.62 42.0 4.14e-01 80.5% 65.0%
3633061 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.62 36.0 4.27e-01 76.0% 83.8%
3462394 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.61 38.0 4.11e-01 94.2% 72.3%
4026510 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.61 39.0 4.12e-01 94.8% 71.9%
3538236 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 36.0 4.21e-01 87.7% 82.7%
3795207 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 40.0 4.49e-01 96.1% 88.7%
3498816 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 36.0 4.32e-01 79.2% 88.6%
3740762 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.59 40.0 4.68e-01 78.6% 100.0%
3592819 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.58 41.0 4.63e-01 93.5% 94.2%
3173373 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.58 39.0 4.43e-01 98.1% 91.3%
3657954 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.58 39.0 4.38e-01 95.5% 90.4%
4029321 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.57 40.0 4.34e-01 71.4% 97.7%
3607577 304.9.1.58 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Nup35_RRM_2 0.57 37.0 4.22e-01 76.6% 87.0%
3959820 304.11.1.0 ↗ a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase 0.57 29.0 3.58e-01 70.8% 80.0%
3494930 304.9.1.83 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1, RBM39linker 0.56 40.0 3.26e-01 87.0% 41.1%
3632184 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.56 37.0 4.03e-01 81.2% 80.8%
3808598 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.56 38.0 4.22e-01 70.8% 87.5%
3321817 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.56 35.0 3.91e-01 95.5% 80.0%
3272207 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.56 38.0 4.30e-01 90.3% 90.0%
3301489 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.56 37.0 4.31e-01 96.1% 94.5%
4089614 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.55 37.0 4.28e-01 70.8% 94.5%
3404821 304.9.1.81 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RBD_AKAP-17A 0.55 39.0 3.72e-01 71.4% 76.6%
3334515 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.55 38.0 4.33e-01 87.7% 92.5%
4405598 304.24.1.0 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.54 35.0 4.19e-01 98.1% 100.0%
3772593 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.54 37.0 3.52e-01 90.3% 58.9%
3837280 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.54 39.0 4.43e-01 87.0% 99.1%
3316754 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.54 37.0 4.30e-01 70.8% 100.0%
3487988 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.53 40.0 3.95e-01 80.5% 73.8%
4026511 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.53 36.0 4.24e-01 91.6% 100.0%
3477312 304.9.1.81 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RBD_AKAP-17A 0.53 37.0 3.22e-01 71.4% 53.8%
3497701 304.9.1.81 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RBD_AKAP-17A 0.53 37.0 3.81e-01 71.4% 85.1%
3933313 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.51 42.0 4.44e-01 89.0% 100.0%
D2 high residues 191-443
PDB
Domain cluster: rep: DNAPol__YP_009116659__Tipula_oleracea_nudivirus__1546257__D190-428
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF13482.13 best RNase_H_2 32.1 1.50e-07 76.7% 68.5%
PF03104.26 DNA_pol_B_exo1 30.9 2.60e-07 65.2% 51.6%
D3 high residues 903-1080
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2k3pA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.66 36.0 4.28e-01 96.6% 78.4%
1zk8B02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 39.0 4.40e-01 98.9% 77.3%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 40.0 4.02e-01 97.8% 62.0%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 42.0 4.59e-01 98.9% 82.1%
2lsgA00 1.20.58.1280 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain 0.62 30.0 3.89e-01 92.1% 81.4%
2np5D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 40.0 4.21e-01 98.9% 72.8%
3cjdA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 37.0 3.72e-01 98.9% 59.3%
2dg8D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 37.0 3.76e-01 98.9% 61.8%
2mx8A01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.57 35.0 4.16e-01 100.0% 92.9%
2hjmA01 1.20.120.460 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like 0.57 26.0 3.48e-01 96.1% 83.7%
2fx0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 35.0 4.04e-01 97.2% 83.3%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.56 29.0 3.52e-01 97.2% 75.4%
3a11B01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.56 33.0 3.89e-01 96.1% 83.2%
1e6vA03 1.20.840.10 Mainly Alpha › Up-down Bundle › Methyl-coenzyme M Reductase; Chain B, domain 2 › Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal 0.55 41.0 3.79e-01 100.0% 60.4%
6ko8A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 33.0 3.32e-01 98.9% 59.5%
4ap2B01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.51 32.0 3.60e-01 90.4% 80.6%
2dkwA00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.51 26.0 2.99e-01 83.1% 64.1%
1pqsA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.51 22.0 3.09e-01 82.6% 87.0%
1ed1A00 1.10.150.90 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 0.51 26.0 3.16e-01 98.3% 73.7%
4jykA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.50 34.0 3.74e-01 97.8% 84.6%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4022147 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.62 33.0 3.39e-01 90.4% 52.4%
4939465 622.1.1.0 ↗ alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.57 30.0 3.65e-01 82.0% 77.4%
4959676 1075.1.1.3 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_2 0.56 47.0 4.32e-01 98.9% 69.1%
3959642 5067.1.1.0 ↗ alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.54 31.0 2.34e-01 86.0% 21.3%
3738888 109.4.1.1242 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_RRP12_N 0.54 30.0 2.79e-01 100.0% 40.4%
2642640 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.53 34.0 3.63e-01 94.9% 74.5%
3712348 5057.1.1.0 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.52 35.0 3.18e-01 97.2% 47.5%
3949818 191.1.1.0 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.52 36.0 3.85e-01 98.9% 80.0%
4975029 1075.1.1.0 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.52 41.0 4.18e-01 98.3% 84.6%
3968089 3883.1.1.1 ↗ alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.51 36.0 3.43e-01 93.3% 60.5%
4990692 7064.1.1.0 ↗ alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 0.51 33.0 3.53e-01 82.0% 73.1%
D4 medium residues 526-541_633-676_750-836
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 32.9 4.60e-08 98.0% 11.7%
CATH (63)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.90 47.0 5.64e-01 73.5% 73.3%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.86 40.0 5.16e-01 77.6% 74.7%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.85 52.0 5.36e-01 73.5% 64.1%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.83 56.0 6.53e-01 84.4% 94.3%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.83 47.0 6.08e-01 75.5% 95.5%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.82 29.0 4.19e-01 74.8% 66.7%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.82 38.0 5.64e-01 71.4% 100.0%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.82 49.0 5.97e-01 72.8% 89.8%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.81 43.0 4.92e-01 78.9% 67.5%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.81 47.0 5.07e-01 70.1% 66.9%
3u0cA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.79 56.0 5.53e-01 74.1% 69.5%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.78 48.0 5.78e-01 70.7% 91.0%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.78 47.0 4.77e-01 70.1% 61.4%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.78 39.0 4.80e-01 76.2% 74.7%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.78 43.0 5.50e-01 75.5% 92.0%
2zdiB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.77 55.0 6.44e-01 72.8% 100.0%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 46.0 5.00e-01 78.2% 71.1%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 48.0 5.72e-01 78.2% 89.3%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.77 55.0 4.55e-01 75.5% 44.9%
5y06A01 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 52.0 4.41e-01 78.2% 44.5%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.76 43.0 5.61e-01 72.8% 100.0%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.75 38.0 4.23e-01 81.6% 60.0%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 47.0 5.47e-01 77.6% 86.9%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.74 52.0 6.13e-01 72.8% 98.1%
1l8dA00 1.10.287.510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.74 50.0 6.00e-01 73.5% 98.1%
3tulB00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.74 57.0 5.99e-01 82.3% 88.0%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.73 48.0 5.73e-01 88.4% 99.0%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.73 50.0 5.95e-01 70.7% 98.1%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 50.0 4.18e-01 75.5% 42.4%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.72 51.0 3.92e-01 73.5% 34.6%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.72 43.0 4.76e-01 78.9% 73.1%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 52.0 4.94e-01 81.6% 63.6%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 40.0 4.58e-01 81.0% 72.3%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.71 48.0 5.01e-01 91.8% 74.4%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.71 35.0 4.87e-01 72.8% 100.0%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.71 44.0 4.49e-01 70.7% 61.9%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 39.0 4.53e-01 81.0% 75.5%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.71 48.0 4.24e-01 73.5% 47.9%
2qe7G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.71 46.0 5.59e-01 72.1% 100.0%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 53.0 5.48e-01 76.9% 89.9%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 58.0 4.59e-01 85.0% 75.6%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.70 45.0 4.89e-01 76.9% 76.0%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.70 41.0 5.21e-01 71.4% 100.0%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 51.0 4.99e-01 75.5% 84.5%
3vbbE01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.69 54.0 6.00e-01 81.0% 100.0%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.69 43.0 5.05e-01 72.1% 90.2%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.68 47.0 4.75e-01 73.5% 69.9%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.68 57.0 4.98e-01 87.1% 87.1%
2pmsC00 6.10.140.920 Special › Helix non-globular › Helix Hairpins › 0.68 47.0 5.50e-01 79.6% 95.4%
6h9xA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.67 45.0 5.20e-01 73.5% 98.0%
4q4hA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.66 54.0 4.12e-01 85.7% 48.4%
1m6nA04 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.66 33.0 3.44e-01 78.2% 50.4%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.65 31.0 3.34e-01 90.5% 50.8%
1e1dA02 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 32.0 4.09e-01 85.0% 79.8%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.64 41.0 5.01e-01 71.4% 100.0%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.61 50.0 4.62e-01 85.7% 87.4%
3aonA00 1.10.287.3240 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 43.0 4.02e-01 73.5% 92.6%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 48.0 4.06e-01 84.4% 79.2%
6bl6B01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.59 50.0 3.88e-01 90.5% 46.5%
7metA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.59 50.0 3.91e-01 90.5% 49.5%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.59 50.0 3.80e-01 89.8% 94.8%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.58 43.0 4.28e-01 77.6% 78.3%
3zdqA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.58 50.0 3.82e-01 92.5% 44.7%
ECOD (82)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3487203 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.93 52.0 6.96e-01 76.2% 97.6%
4018440 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.92 54.0 6.79e-01 75.5% 91.6%
4937862 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.89 52.0 6.08e-01 75.5% 79.1%
3634896 622.4.1.0 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.88 53.0 5.98e-01 73.5% 76.5%
4406698 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.88 53.0 6.70e-01 75.5% 94.7%
5011532 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.87 53.0 6.58e-01 76.2% 93.7%
3359919 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.87 53.0 6.18e-01 78.2% 83.3%
4384750 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.86 53.0 6.57e-01 75.5% 95.8%
5054540 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.85 53.0 3.87e-01 75.5% 26.7%
3237980 2003.1.2.18 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.84 53.0 3.37e-01 74.1% 15.6%
3594486 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.84 52.0 5.78e-01 77.6% 76.7%
3564399 3755.3.1.282 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tmemb_cc2 0.83 51.0 5.82e-01 70.1% 80.0%
4003222 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.83 53.0 6.41e-01 79.6% 95.0%
4983118 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.82 52.0 6.60e-01 74.1% 100.0%
3365701 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.82 55.0 6.37e-01 74.8% 90.9%
3559003 192.2.1.1 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.82 55.0 6.70e-01 74.8% 100.0%
5042020 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.82 49.0 6.43e-01 72.1% 100.0%
4029359 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.82 51.0 5.44e-01 79.6% 71.3%
4303085 3755.3.1.467 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C 0.81 49.0 5.46e-01 72.1% 74.2%
3609611 4970.1.1.0 ↗ alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.81 58.0 6.06e-01 76.9% 79.3%
4016635 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.81 53.0 6.50e-01 81.6% 99.0%
4024105 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.80 54.0 4.28e-01 78.2% 36.4%
3836427 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.80 53.0 6.50e-01 77.6% 99.0%
3825161 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.80 53.0 4.30e-01 75.5% 38.1%
3273862 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.80 49.0 6.17e-01 79.6% 96.8%
3996264 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.79 55.0 5.18e-01 74.8% 60.6%
4963973 1203.1.2.0 ↗ alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 0.79 56.0 5.34e-01 86.4% 62.9%
5009131 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 52.0 5.02e-01 74.8% 60.0%
4163282 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 53.0 4.85e-01 73.5% 54.6%
4177393 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 52.0 5.33e-01 73.5% 69.0%
3898401 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 52.0 4.28e-01 78.2% 40.4%
3707204 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 55.0 4.27e-01 75.5% 36.7%
4175684 3291.1.1.232 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Paralemmin 0.78 54.0 5.71e-01 74.1% 79.2%
3470739 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 54.0 4.69e-01 75.5% 48.8%
1171038 3755.3.1.148 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CT398_CC 0.78 54.0 4.83e-01 74.8% 53.9%
3613932 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.78 55.0 6.22e-01 76.2% 92.2%
3932665 193.1.1.0 ↗ alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like 0.77 54.0 4.32e-01 74.8% 40.0%
4935333 3755.3.1.637 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.77 55.0 5.48e-01 74.8% 70.7%
5065057 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.77 54.0 5.34e-01 74.8% 67.7%
4066169 109.4.1.359 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.77 53.0 3.38e-01 82.3% 15.6%
4484997 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.77 48.0 5.08e-01 76.2% 68.9%
4988623 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.77 55.0 4.37e-01 76.2% 40.0%
4979981 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.77 54.0 6.29e-01 85.0% 96.4%
3733141 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 53.0 5.37e-01 70.1% 72.4%
3657123 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.76 48.0 6.10e-01 83.7% 100.0%
3819281 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 53.0 4.76e-01 71.4% 58.5%
3995294 1065.1.1.0 ↗ alpha bundles › SPX domain › SPX domain › SPX domain 0.75 46.0 5.00e-01 73.5% 72.0%
4936791 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.75 53.0 3.63e-01 75.5% 23.4%
3615971 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 54.0 4.87e-01 73.5% 57.4%
3548194 192.2.1.18 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.75 52.0 6.01e-01 74.1% 95.5%
4576287 3755.3.1.471 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Paralemmin 0.74 55.0 5.38e-01 75.5% 74.8%
4994979 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.74 55.0 4.99e-01 76.2% 94.2%
3299419 5086.1.1.126 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PPI_helical 0.74 54.0 5.04e-01 75.5% 86.1%
5039649 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 56.0 6.25e-01 83.7% 96.7%
3583684 148.1.3.11 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › MT 0.73 49.0 3.95e-01 75.5% 37.0%
5073085 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.73 51.0 4.93e-01 82.3% 64.0%
5082443 3755.1.1.0 ↗ alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.73 52.0 5.25e-01 75.5% 73.1%
3393794 3922.1.1.211 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DRC7_C 0.72 53.0 5.57e-01 78.9% 82.2%
3760483 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 57.0 5.11e-01 81.6% 62.6%
4315070 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 53.0 4.99e-01 76.2% 66.9%
3934585 3755.3.1.465 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A 0.70 54.0 5.44e-01 81.0% 78.0%
3713604 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.70 52.0 3.93e-01 76.9% 42.8%
4001187 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 54.0 5.05e-01 80.3% 95.4%
3714442 4177.1.1.5 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.69 56.0 4.61e-01 84.4% 85.6%
5079925 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.69 56.0 5.09e-01 83.7% 67.6%
4950969 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.68 57.0 3.90e-01 87.1% 48.3%
3767783 192.2.1.19 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › FAM186A-B_C 0.68 58.0 5.79e-01 88.4% 88.7%
3766955 192.7.1.17 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › FAM186A-B_C 0.68 57.0 5.82e-01 88.4% 91.7%
3852832 3922.1.1.72 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › FAM186A-B_C 0.68 57.0 5.72e-01 88.4% 88.7%
4969095 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 53.0 3.81e-01 83.0% 34.0%
3560590 3755.3.1.142 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › FAM186A-B_C 0.67 56.0 5.64e-01 88.4% 88.7%
4002750 5086.1.1.118 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › BBS2_hp 0.67 50.0 5.26e-01 81.0% 86.9%
3923798 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.67 54.0 4.54e-01 84.4% 76.2%
3933335 2004.1.1.198 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.66 53.0 3.54e-01 83.7% 40.0%
3402327 3755.3.1.324 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 0.66 47.0 4.44e-01 73.5% 62.4%
3864210 2004.1.1.250 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Kinesin,Microtub_bd 0.66 52.0 3.42e-01 81.6% 21.3%
3164951 5094.1.1.1 ↗ a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH 0.66 46.0 4.39e-01 76.2% 61.2%
3788782 2004.1.1.199 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B 0.66 52.0 3.51e-01 83.0% 40.2%
3804937 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.65 50.0 4.84e-01 78.9% 78.1%
3715891 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 47.0 4.55e-01 76.2% 66.7%
3923562 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 56.0 3.85e-01 93.9% 56.1%
4515899 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 44.0 4.17e-01 72.8% 70.6%
D5 medium residues 542-576_596-632
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2dp9A01 2.30.130.30 Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › Hypothetical protein. 0.62 37.0 3.30e-01 100.0% 42.0%
1kwmA01 3.30.70.340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Metallocarboxypeptidase-like 0.55 38.0 3.63e-01 73.6% 95.5%
3ldgA01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.54 40.0 3.11e-01 86.1% 77.8%
1a9xA03 3.30.1490.20 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain 0.54 44.0 4.52e-01 98.6% 95.7%
1wyzA02 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.54 45.0 4.01e-01 98.6% 84.5%
1yb3A00 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.53 46.0 3.59e-01 100.0% 50.3%
2ws9201 2.60.120.20 Mainly Beta › Sandwich › Jelly Rolls › 0.51 42.0 3.21e-01 98.6% 85.6%
6k2lA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.51 43.0 3.81e-01 98.6% 98.2%
3lrkA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.50 43.0 3.46e-01 97.2% 83.0%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3172078 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.59 52.0 3.65e-01 100.0% 38.3%
5081834 1.1.9.0 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain 0.55 36.0 2.95e-01 100.0% 35.6%
3388188 206.1.3.43 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DUF6815 0.55 48.0 3.38e-01 100.0% 76.2%
3502381 206.1.1.28 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.55 47.0 3.10e-01 97.2% 36.0%
3507705 206.1.3.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATP-grasp_2 0.54 45.0 3.23e-01 100.0% 79.2%
3594055 7567.1.1.0 ↗ a/b three-layered sandwiches › LmbE-like › LmbE-like › LmbE-like 0.54 41.0 2.99e-01 86.1% 89.3%
3268540 7567.1.1.1 ↗ a/b three-layered sandwiches › LmbE-like › LmbE-like › LmbE-like › PIG-L 0.53 40.0 2.88e-01 86.1% 88.5%
3560567 304.34.1.1 ↗ a+b two layers › Alpha-beta plaits › Nucleoside diphosphate kinases › Nucleoside diphosphate kinases › NDK 0.52 37.0 2.85e-01 75.0% 82.3%
3506123 7567.1.1.1 ↗ a/b three-layered sandwiches › LmbE-like › LmbE-like › LmbE-like › PIG-L 0.51 39.0 2.88e-01 86.1% 88.8%
3987280 320.1.1.3 ↗ a+b two layers › R3H domain-like › R3H domain › R3H domain › YlmH_1st 0.50 37.0 3.54e-01 100.0% 67.1%
3737630 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.50 43.0 3.20e-01 100.0% 50.7%
D6 medium residues 837-902
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 25.9 6.10e-06 95.5% 13.9%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1s7iA00 3.30.70.1060 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel 0.64 44.0 3.55e-01 71.2% 60.5%
2yj6A02 3.40.1110.10 Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N 0.61 42.0 3.74e-01 100.0% 50.5%
5kmpB00 3.50.50.100 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › 0.57 48.0 3.03e-01 100.0% 50.6%
1trbA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.56 45.0 3.37e-01 93.9% 52.9%
5j60A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 45.0 3.31e-01 93.9% 50.3%
5yjwA00 3.50.50.100 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › 0.55 45.0 2.84e-01 100.0% 21.8%
5x1yA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 45.0 3.85e-01 100.0% 68.9%
4fczA00 3.10.450.710 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Tgt2/MlaC 0.55 46.0 3.45e-01 100.0% 62.3%
3wj2B00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 46.0 3.09e-01 100.0% 73.0%
3f8dB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 45.0 3.41e-01 100.0% 50.3%
1q7fB00 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.54 43.0 2.88e-01 90.9% 95.0%
4omfB02 3.10.450.750 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 32.0 3.73e-01 100.0% 87.2%
6qp9B01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.53 39.0 2.39e-01 81.8% 44.5%
3oc4A02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 43.0 3.70e-01 100.0% 67.5%
3d1cA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 43.0 3.03e-01 100.0% 50.6%
1ex4B02 2.30.30.10 Mainly Beta › Roll › SH3 type barrels. › Integrase, C-terminal domain superfamily, retroviral 0.51 31.0 3.27e-01 84.8% 67.8%
5niiB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 41.0 3.17e-01 100.0% 50.3%
1onfA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 41.0 3.56e-01 100.0% 82.2%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3575094 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.85 78.0 6.72e-01 100.0% 80.0%
5064336 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.65 42.0 3.73e-01 100.0% 46.3%
4975610 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.64 44.0 3.60e-01 100.0% 40.0%
3971964 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.63 44.0 3.53e-01 100.0% 38.4%
4953763 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.63 44.0 3.70e-01 100.0% 43.6%
5053450 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.63 43.0 3.60e-01 100.0% 41.7%
4950588 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.63 43.0 3.60e-01 100.0% 41.7%
1152945 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.63 43.0 3.98e-01 100.0% 55.8%
3723049 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.62 43.0 3.58e-01 100.0% 41.7%
4943940 267.1.1.2 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Hydrolase 0.62 43.0 3.50e-01 100.0% 38.4%
3959003 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.62 42.0 3.88e-01 100.0% 55.3%
3789341 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.61 50.0 3.24e-01 93.9% 36.8%
5024840 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.61 40.0 3.60e-01 100.0% 47.4%
3951184 2003.1.2.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox, Pyr_redox_2 0.61 51.0 3.15e-01 100.0% 29.8%
4953802 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.61 42.0 3.45e-01 100.0% 40.0%
3943273 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.61 40.0 3.38e-01 100.0% 40.0%
4979783 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.60 42.0 3.48e-01 100.0% 41.7%
4937913 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.60 41.0 3.41e-01 100.0% 40.0%
3180612 2003.1.2.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox, Pyr_redox_2 0.59 51.0 3.18e-01 100.0% 30.6%
4023722 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.59 48.0 3.06e-01 100.0% 50.1%
4163703 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.59 42.0 3.37e-01 100.0% 38.5%
3651627 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.58 41.0 3.09e-01 100.0% 30.3%
4028547 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.57 41.0 2.99e-01 100.0% 27.0%
3387868 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.57 40.0 3.42e-01 98.5% 46.7%
3197429 244.2.1.10 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › NDH2_C 0.56 40.0 2.62e-01 77.3% 74.8%
2140326 2003.1.2.25 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.55 46.0 3.98e-01 100.0% 83.0%
4945118 2003.1.2.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 0.55 45.0 3.38e-01 100.0% 47.5%
4927970 2003.1.2.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 0.55 45.0 3.73e-01 100.0% 71.4%
3946976 2003.1.2.161 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › PF30338 0.54 44.0 3.41e-01 98.5% 90.9%
3352286 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.53 40.0 3.24e-01 100.0% 40.8%
3283135 2003.1.2.8 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_2,Pyr_redox_2 0.53 42.0 3.07e-01 92.4% 47.6%
3839352 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.53 38.0 3.14e-01 98.5% 43.5%
3589056 2003.1.2.56 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › NAD_binding_9 0.52 42.0 2.66e-01 100.0% 32.6%
4031081 2003.1.2.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox, Pyr_redox_2 0.52 43.0 2.83e-01 100.0% 33.4%
5041793 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.52 42.0 3.85e-01 92.4% 84.4%
5084069 2003.1.2.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 0.51 43.0 3.26e-01 100.0% 52.8%
3440048 2003.1.2.8 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_2,Pyr_redox_2 0.51 42.0 3.15e-01 100.0% 50.0%
5032793 2003.1.2.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2 0.50 41.0 3.08e-01 93.9% 54.1%