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DNA_polymerase
Euk-VirDiatraea_saccharalis_granulovirus
DNA_polymerase__YP_009182295__Diatraea_saccharalis_granulovirus__1675862
Identity
- Accession:
- YP_009182295 ↗
- Protein ID:
- DNA_polymerase
- Kingdom:
- euk
Quality
85.2
mean pLDDT
Taxonomy
TaxID: 1675862
Cluster
View cluster (158 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 176-415
Domain cluster:
rep: DNA_polymerase__YP_009118564__Condylorrhiza_vestigialis_MNPV__1592576__D196-404
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF10108.16 best | DNA_pol_B_exo2 | 32.0 | 1.40e-07 | 90.0% | 65.6% |
| PF03104.26 | DNA_pol_B_exo1 | 90.9 | 1.20e-25 | 72.5% | 72.3% |
D2
medium
residues 1-175
Domain cluster:
rep: DNA_polymerase__YP_010084862__Shrimp_hemocyte_iridescent_virus__2039780__D2-200
D3
medium
residues 418-475_477-636
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 61.3 | 1.10e-16 | 81.2% | 31.8% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.76 | 23.0 | 4.58e-01 | 88.1% | 100.0% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 21.0 | 3.72e-01 | 90.4% | 76.7% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 30.0 | 4.63e-01 | 95.0% | 92.4% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.71 | 25.0 | 4.43e-01 | 85.8% | 100.0% |
| 2p4vA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.64 | 24.0 | 3.86e-01 | 81.7% | 92.1% |
| 2x1lA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.63 | 28.0 | 3.18e-01 | 98.2% | 51.7% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.58 | 28.0 | 3.41e-01 | 95.4% | 67.6% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.57 | 27.0 | 3.59e-01 | 95.0% | 83.8% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.55 | 30.0 | 3.70e-01 | 95.9% | 82.7% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 30.0 | 3.95e-01 | 96.8% | 98.3% |
| 2a2cA03 | 1.20.1440.340 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.53 | 31.0 | 3.79e-01 | 91.7% | 89.1% |
| 5nohA00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.52 | 20.0 | 2.81e-01 | 73.9% | 69.9% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 23.0 | 2.88e-01 | 95.9% | 66.0% |
| 4dkcB00 | 1.20.1250.80 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-34 | 0.51 | 25.0 | 2.98e-01 | 97.2% | 65.6% |
| 3purA03 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 22.0 | 2.93e-01 | 96.3% | 73.6% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4597007 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.92 | 19.0 | 5.27e-01 | 89.0% | 100.0% |
| 4565383 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.90 | 21.0 | 5.28e-01 | 91.3% | 100.0% |
| 4544002 | 192.6.1.1 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE | 0.90 | 21.0 | 5.22e-01 | 91.7% | 100.0% |
| 3795985 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.82 | 25.0 | 4.25e-01 | 95.0% | 74.1% |
| 4932480 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.82 | 48.0 | 4.79e-01 | 72.0% | 58.2% |
| 4213046 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.81 | 26.0 | 5.01e-01 | 82.6% | 100.0% |
| 4942685 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.81 | 63.0 | 4.65e-01 | 100.0% | 35.5% |
| None | — | 0.79 | 62.0 | 4.28e-01 | 100.0% | 27.3% | |
| 3558196 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.79 | 61.0 | 5.49e-01 | 100.0% | 60.7% |
| 4956224 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.79 | 54.0 | 5.32e-01 | 93.6% | 65.1% |
| 4982660 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.78 | 48.0 | 4.85e-01 | 94.0% | 61.9% |
| 4977369 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.77 | 58.0 | 5.47e-01 | 99.1% | 66.4% |
| 4970593 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.77 | 57.0 | 5.44e-01 | 99.1% | 66.4% |
| 3742811 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.76 | 28.0 | 3.87e-01 | 93.6% | 64.3% |
| 5005286 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.76 | 58.0 | 5.09e-01 | 98.2% | 55.7% |
| 4959101 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.76 | 53.0 | 5.04e-01 | 85.8% | 62.4% |
| 5073476 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.76 | 47.0 | 4.63e-01 | 85.3% | 58.3% |
| 3801150 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.75 | 51.0 | 4.55e-01 | 83.9% | 51.2% |
| 4997717 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.74 | 61.0 | 5.32e-01 | 100.0% | 59.4% |
| 4958744 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.73 | 31.0 | 4.35e-01 | 93.6% | 79.1% |
| 4958743 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.72 | 31.0 | 4.26e-01 | 93.6% | 76.5% |
| 5044377 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.72 | 49.0 | 4.72e-01 | 85.8% | 61.2% |
| 3684974 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.72 | 63.0 | 4.28e-01 | 100.0% | 29.5% |
| 3484036 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.71 | 50.0 | 4.57e-01 | 72.0% | 60.4% |
| 3480546 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.70 | 50.0 | 4.64e-01 | 82.6% | 59.6% |
| 5012084 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.70 | 45.0 | 4.45e-01 | 85.3% | 61.8% |
| 3253283 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.69 | 30.0 | 4.50e-01 | 96.3% | 92.6% |
| 3924651 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.69 | 28.0 | 4.14e-01 | 96.3% | 84.2% |
| 4000281 | 192.20.1.0 ↗ | alpha bundles › Long alpha-hairpin › helical hairpin domain in transcriptional anti-activator ExsD › helical hairpin domain in transcriptional anti-activator ExsD | 0.68 | 29.0 | 4.25e-01 | 98.6% | 86.0% |
| 4958742 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 29.0 | 3.84e-01 | 95.0% | 69.6% |
| 4976290 | 192.1.1.0 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain | 0.66 | 26.0 | 4.22e-01 | 95.0% | 97.5% |
| 3876247 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 30.0 | 3.96e-01 | 95.9% | 82.5% |
| 5056427 | 3843.1.1.38 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › T4SS_pilin | 0.61 | 28.0 | 3.96e-01 | 91.7% | 86.4% |
| 5032045 | 4163.1.1.0 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like | 0.61 | 27.0 | 3.99e-01 | 97.7% | 92.0% |
| 4947400 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.57 | 32.0 | 3.96e-01 | 94.5% | 85.0% |
| 4108773 | 142.1.1.1 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r1_2,Sigma70_r2 | 0.54 | 32.0 | 2.77e-01 | 73.9% | 38.5% |
| 4998819 | 2484.1.1.124 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › OrfB_IS605 | 0.52 | 29.0 | 3.70e-01 | 71.6% | 90.8% |
| 3601853 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.52 | 31.0 | 3.68e-01 | 96.3% | 86.2% |
| 3565062 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.51 | 29.0 | 3.57e-01 | 95.4% | 86.4% |
D4
medium
residues 637-727
Domain cluster:
rep: DNA_polymerase__YP_003422477__Pseudalatia_unipuncta_granulovirus__36355__D676-752
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 26.2 | 4.90e-06 | 97.8% | 11.5% |
D5
medium
residues 890-932_971-1025
Domain cluster:
rep: polymerase__YP_002854676__Euproctis_pseudoconspersa_nucleopolyhedrovirus__307467__D973-1018_1035-1067
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4942434 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.54 | 37.0 | 3.80e-01 | 79.6% | 73.7% |
| 4991403 | 2004.1.1.308 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21 | 0.52 | 38.0 | 2.60e-01 | 76.5% | 36.7% |
| 5054303 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.51 | 33.0 | 3.60e-01 | 80.6% | 80.0% |