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DNA_polymerase
Euk-VirOperophtera_brumata_nucleopolyhedrovirus
DNA_polymerase__YP_009552625__Operophtera_brumata_nucleopolyhedrovirus__1046267
Identity
- Accession:
- YP_009552625 ↗
- Protein ID:
- DNA_polymerase
- Kingdom:
- euk
Quality
84.6
mean pLDDT
Taxonomy
Naldaviricetes›
Lefavirales›
Baculoviridae›
Alphabaculovirus›
Operophtera_brumata_nucleopolyhedrovirus
TaxID: 1046267
Cluster
View cluster (158 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 748-807_819-912
D2
medium
residues 1-183
D3
medium
residues 184-273
Domain cluster:
rep: DNA_polymerase_elongation_subunit_family_B__YP_010088005__Lymphocystis_disease_virus_4__2704413__D159-241
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03104.26 best | DNA_pol_B_exo1 | 37.1 | 3.40e-09 | 100.0% | 38.4% |
D4
medium
residues 274-342
Domain cluster:
rep: DNA_polymerase__YP_008378438__Choristoneura_rosaceana_nucleopolyhedrovirus__58094__D271-327
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03104.26 best | DNA_pol_B_exo1 | 28.3 | 1.60e-06 | 100.0% | 28.5% |
D5
medium
residues 343-406
D6
medium
residues 407-471
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4fvmA04 | 6.10.10.100 | Special › Helix non-globular › Helicase, Ruva Protein; domain 3 › | 0.83 | 57.0 | 6.54e-01 | 87.7% | 100.0% |
| 3gpvA00 | 1.10.1660.10 | Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › | 0.58 | 40.0 | 3.43e-01 | 73.8% | 73.5% |
| 1t3aA00 | 3.90.1240.10 | Alpha Beta › Alpha-Beta Complex › Zincin-like › "Metalloproteases (""zincins""), catalytic domain like" | 0.57 | 40.0 | 2.52e-01 | 76.9% | 50.7% |
| 3rk6A00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 44.0 | 3.16e-01 | 92.3% | 65.9% |
| 8be0A01 | 3.40.91.90 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain | 0.54 | 41.0 | 3.10e-01 | 87.7% | 91.1% |
| 2fd5A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 41.0 | 3.33e-01 | 87.7% | 87.1% |
| 2vx7A00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.51 | 40.0 | 2.52e-01 | 86.2% | 40.9% |
| 6k9pB02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.50 | 41.0 | 3.27e-01 | 96.9% | 75.0% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3368695 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.86 | 56.0 | 3.38e-01 | 84.6% | 11.3% |
| 3710418 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.84 | 55.0 | 3.35e-01 | 84.6% | 11.7% |
| 5025208 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.81 | 54.0 | 3.61e-01 | 87.7% | 19.6% |
| 4888481 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.80 | 60.0 | 3.91e-01 | 100.0% | 19.5% |
| 3496492 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.73 | 57.0 | 3.66e-01 | 98.5% | 18.6% |
| 3206356 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.72 | 56.0 | 3.41e-01 | 98.5% | 13.5% |
| 3684974 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.64 | 58.0 | 3.29e-01 | 100.0% | 30.6% |
| 3938116 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.59 | 45.0 | 3.11e-01 | 86.2% | 50.2% |
| 3490651 | 141.1.1.0 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases | 0.59 | 48.0 | 2.96e-01 | 92.3% | 52.6% |
| 3590899 | 2007.1.2.11 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_4 | 0.58 | 39.0 | 2.91e-01 | 70.8% | 80.9% |
| 3887540 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.57 | 44.0 | 2.60e-01 | 86.2% | 27.4% |
| 4043003 | 601.7.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › GlnD_UR_UTase | 0.56 | 41.0 | 3.06e-01 | 80.0% | 31.8% |
| 4033688 | 101.1.2.92 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_11 | 0.54 | 30.0 | 3.00e-01 | 83.1% | 50.0% |
| 3871096 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 40.0 | 2.62e-01 | 81.5% | 29.7% |
| 3530542 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 39.0 | 2.63e-01 | 81.5% | 37.6% |
| 5069346 | 219.1.1.13 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core | 0.54 | 43.0 | 3.07e-01 | 87.7% | 68.8% |
| 3560659 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 40.0 | 2.61e-01 | 81.5% | 31.5% |
| 3474413 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.53 | 39.0 | 2.52e-01 | 83.1% | 28.6% |
| 3940179 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.52 | 35.0 | 2.62e-01 | 70.8% | 49.5% |
| 3687833 | 5073.1.1.18 ↗ | alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Hydrolase | 0.52 | 43.0 | 2.58e-01 | 100.0% | 63.8% |
| 3532358 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.51 | 42.0 | 2.72e-01 | 95.4% | 92.0% |
| 3395806 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.51 | 39.0 | 2.60e-01 | 86.2% | 55.1% |
| 3251651 | 2003.1.2.18 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.50 | 41.0 | 2.50e-01 | 100.0% | 67.3% |
| 3922833 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.50 | 40.0 | 2.80e-01 | 100.0% | 55.6% |
| 3612163 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.50 | 38.0 | 2.73e-01 | 87.7% | 60.0% |
D7
medium
residues 472-637
Domain cluster:
rep: DNA_polymerase__YP_010086932__Cryptophlebia_peltastica_nucleopolyhedrovirus__2304025__D494-537_560-649
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 58.6 | 7.20e-16 | 95.2% | 33.8% |
D8
medium
residues 638-737
Domain cluster:
rep: DNA_polymerase_catalytic_subunit__YP_009552191__Malacosoma_neustria_nucleopolyhedrovirus__38012__D557-567_668-765
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 35.2 | 8.70e-09 | 100.0% | 17.9% |