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DNA_polymerase

Euk-Vir

Western_grey_kangaroopox_virus

DNA_polymerase__YP_010085171__Western_grey_kangaroopox_virus__1566307

Identity

Accession:
YP_010085171 ↗
Protein ID:
DNA_polymerase
Kingdom:
euk

Quality

78.8 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Macropopoxvirus› Western_grey_kangaroopox_virus

TaxID: 1566307

Cluster

View cluster (158 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 164-338_439-486
PDB
Domain cluster: rep: DNA_polymerase_catalytic_subunit__YP_401712__Human_gammaherpesvirus_4__10376__D288-457
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF03104.26 best DNA_pol_B_exo1 87.0 1.80e-24 81.2% 72.3%
PF08408.17 DNA_pol_B_3 61.3 1.60e-16 29.1% 30.5%
D2 high residues 344-433
PDB
Domain cluster: rep: DNA_polymerase_elongation_subunit_family_B__YP_009162448__Salmon_gill_poxvirus__1680908__D388-474
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08408.17 best DNA_pol_B_3 64.4 1.70e-17 98.9% 65.6%
CATH (73)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3u28C00 2.40.10.230 Mainly Beta › Beta Barrel › Thrombin, subunit H › Probable tRNA pseudouridine synthase domain 0.71 58.0 5.75e-01 100.0% 85.9%
2dyiA01 2.40.30.60 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › RimM 0.70 55.0 5.75e-01 100.0% 89.3%
4yhbA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.69 64.0 5.56e-01 98.9% 91.5%
3op1A02 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.69 57.0 5.27e-01 94.4% 71.2%
6hhuA01 2.60.40.1220 Mainly Beta › Sandwich › Immunoglobulin-like › 0.68 48.0 5.13e-01 90.0% 85.9%
3lnnA02 2.40.30.170 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Efflux pump adaptor protein, beta barrel domain 0.66 60.0 5.93e-01 98.9% 96.8%
2dgyA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.66 39.0 4.13e-01 97.8% 65.8%
2lp6A00 2.40.10.190 Mainly Beta › Beta Barrel › Thrombin, subunit H › translation elongation factor selb, chain A, domain 4 0.66 57.0 5.68e-01 98.9% 93.4%
2v3mA00 2.40.10.230 Mainly Beta › Beta Barrel › Thrombin, subunit H › Probable tRNA pseudouridine synthase domain 0.66 52.0 5.22e-01 100.0% 83.0%
3fawA01 2.60.40.1220 Mainly Beta › Sandwich › Immunoglobulin-like › 0.66 49.0 4.87e-01 95.6% 76.1%
1wosA04 2.40.30.110 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Aminomethyltransferase beta-barrel domains 0.66 44.0 4.51e-01 82.2% 72.1%
6j0qA02 2.40.30.120 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses 0.66 56.0 5.30e-01 95.6% 95.4%
1krhA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.65 58.0 5.70e-01 100.0% 96.9%
1v5vA03 2.40.30.110 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Aminomethyltransferase beta-barrel domains 0.65 47.0 5.04e-01 81.1% 89.3%
2d9rA00 2.40.30.100 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › AF2212/PG0164-like 0.65 54.0 5.52e-01 98.9% 95.3%
1vf7F01 2.40.30.170 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Efflux pump adaptor protein, beta barrel domain 0.65 58.0 5.58e-01 97.8% 98.0%
1wg1A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.65 41.0 4.58e-01 77.8% 81.7%
5tr9A01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.65 59.0 5.77e-01 97.8% 94.8%
3gwqA01 2.40.37.20 Mainly Beta › Beta Barrel › Lyase, Ornithine Decarboxylase; Chain A, domain 1 › D-serine dehydratase-like domain 0.64 57.0 4.52e-01 100.0% 50.0%
2zbvC02 2.40.30.90 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Bacterial fluorinating enzyme like 0.63 55.0 5.25e-01 94.4% 93.1%
1afiA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 41.0 4.44e-01 80.0% 83.3%
3kyfA02 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.62 53.0 4.85e-01 93.3% 75.2%
1kviA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 43.0 4.55e-01 83.3% 82.3%
1pj5A05 2.40.30.110 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Aminomethyltransferase beta-barrel domains 0.61 46.0 4.85e-01 84.4% 91.0%
3fgeA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.61 52.0 4.26e-01 95.6% 81.4%
1n08A00 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.61 53.0 4.51e-01 100.0% 62.3%
1t7vA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 48.0 4.84e-01 92.2% 85.6%
1rz1A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.60 52.0 4.37e-01 95.6% 77.6%
5aj3Q00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.60 41.0 3.82e-01 98.9% 57.8%
3h2bB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.60 42.0 3.26e-01 73.3% 83.2%
3wdhA01 2.60.40.2320 Mainly Beta › Sandwich › Immunoglobulin-like › 0.60 44.0 4.36e-01 92.2% 74.0%
1v4pC01 3.30.980.10 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Threonyl-trna Synthetase; Chain A, domain 2 0.60 47.0 4.42e-01 84.4% 79.6%
3t05A02 2.40.33.10 Mainly Beta › Beta Barrel › M1 Pyruvate Kinase; Domain 3 › PK beta-barrel domain-like 0.59 51.0 5.02e-01 96.7% 91.8%
3qx3B03 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.59 46.0 4.50e-01 92.2% 77.0%
1j6wA00 3.30.1360.80 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › S-ribosylhomocysteinase (LuxS) 0.59 50.0 4.11e-01 92.2% 54.7%
3rgfA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.58 42.0 4.13e-01 74.4% 69.8%
3cddA01 2.30.300.10 Mainly Beta › Roll › Phage tail proteins - horseshoe like beta roll fold › Baseplate protein-like domain - beta roll fold 0.58 50.0 4.03e-01 96.7% 83.7%
4qjvA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.58 42.0 4.30e-01 92.2% 77.5%
4nn5C01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 39.0 4.07e-01 91.1% 75.0%
2b9kA00 2.20.20.70 Mainly Beta › Single Sheet › Anthopleurin-A › 0.57 31.0 3.99e-01 77.8% 100.0%
3c1mA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.57 49.0 4.05e-01 94.4% 95.1%
2i02A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.57 46.0 4.00e-01 88.9% 70.0%
1vzyA01 3.55.30.10 Alpha Beta › 3-Layer(bab) Sandwich › Hsp33 domain › Hsp33 domain 0.56 46.0 3.43e-01 88.9% 97.9%
3kmuA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.56 41.0 4.16e-01 76.7% 79.3%
1sq2N00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 46.0 4.34e-01 91.1% 95.5%
7l15A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 46.0 4.35e-01 93.3% 79.6%
6gmhK00 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.55 42.0 3.92e-01 91.1% 64.3%
4fkeA01 2.60.40.1730 Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain 0.55 46.0 3.58e-01 96.7% 94.5%
2nmsA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 45.0 4.28e-01 93.3% 79.5%
3zn6A02 2.60.40.3410 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 45.0 4.63e-01 95.6% 96.6%
5w7tA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.54 38.0 3.80e-01 74.4% 74.2%
1g87A02 2.60.40.710 Mainly Beta › Sandwich › Immunoglobulin-like › Endoglucanase-like 0.54 46.0 3.87e-01 95.6% 90.6%
4wz9A01 2.60.40.1730 Mainly Beta › Sandwich › Immunoglobulin-like › tricorn interacting facor f3 domain 0.54 46.0 3.59e-01 97.8% 93.0%
2z0uA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.54 44.0 3.99e-01 93.3% 98.4%
1s7iA00 3.30.70.1060 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel 0.54 41.0 3.71e-01 82.2% 81.5%
3fdwA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.54 45.0 4.07e-01 96.7% 98.5%
3fcsA03 2.60.40.1510 Mainly Beta › Sandwich › Immunoglobulin-like › ntegrin, alpha v. Chain A, domain 3 0.53 46.0 3.97e-01 94.4% 79.1%
5whzH02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 43.0 3.96e-01 91.1% 75.6%
4ofqA02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 45.0 3.86e-01 96.7% 91.6%
7lfbH01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 44.0 4.07e-01 93.3% 81.2%
1hxmB01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 43.0 3.92e-01 92.2% 76.0%
2k8qA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 44.0 3.95e-01 95.6% 72.4%
2cm5A00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.52 44.0 3.85e-01 95.6% 92.3%
2bwqA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.52 44.0 4.05e-01 96.7% 98.4%
4mjjA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.52 44.0 4.10e-01 96.7% 98.3%
2dmgA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.52 43.0 3.80e-01 95.6% 87.3%
2enpA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.51 42.0 3.65e-01 93.3% 89.1%
2iuwA00 2.60.120.590 Mainly Beta › Sandwich › Jelly Rolls › Alpha-ketoglutarate-dependent dioxygenase AlkB-like 0.51 40.0 3.10e-01 84.4% 73.2%
5h4zA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.51 42.0 3.85e-01 96.7% 94.6%
5xogC01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.51 41.0 3.69e-01 92.2% 88.2%
1txkB02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 43.0 4.00e-01 94.4% 92.2%
4en2A02 2.60.40.1170 Mainly Beta › Sandwich › Immunoglobulin-like › Mu homology domain, subdomain B 0.51 43.0 4.11e-01 92.2% 86.5%
2wcrB00 3.10.129.140 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Helicobacter TNF-alpha-Inducing protein 0.51 36.0 3.11e-01 74.4% 73.3%
ECOD (83)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2323865 1.1.7.26 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › DNA_pol_B_3 0.92 76.0 8.02e-01 93.3% 95.1%
5059785 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.74 61.0 6.49e-01 98.9% 100.0%
3515213 1.1.7.25 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › AARP2CN 0.71 58.0 5.93e-01 96.7% 91.8%
3289340 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.70 57.0 6.04e-01 94.4% 98.8%
3485633 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.70 44.0 4.22e-01 98.9% 57.0%
3598416 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.68 43.0 4.44e-01 98.9% 67.1%
4955892 1.1.7.14 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › CTP-dep_RFKase 0.68 62.0 5.29e-01 100.0% 94.3%
3430247 2.1.1.4 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ribosomal_S17 0.67 44.0 4.18e-01 100.0% 57.7%
3171970 1.1.8.5 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain › tRNA_Me_trans_C 0.67 51.0 5.17e-01 82.2% 84.4%
3282462 1.1.8.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain › Beta-barrel_CAF17_C 0.67 45.0 4.82e-01 81.1% 82.7%
4600806 2.1.1.4 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ribosomal_S17 0.66 43.0 4.04e-01 100.0% 54.5%
3271700 1.1.7.25 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › AARP2CN 0.66 61.0 6.12e-01 100.0% 100.0%
4024062 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.66 42.0 4.60e-01 97.8% 78.4%
4638448 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.66 56.0 5.32e-01 100.0% 79.0%
3834903 2.1.1.4 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ribosomal_S17 0.66 42.0 4.07e-01 98.9% 58.0%
134433 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.66 49.0 4.95e-01 95.6% 79.5%
3785228 1.1.7.24 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_8 0.66 59.0 5.63e-01 100.0% 89.5%
3286458 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.66 58.0 5.21e-01 97.8% 95.2%
4999334 304.165.1.4 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 › HVO_2525_N 0.65 58.0 5.22e-01 100.0% 73.6%
4098290 1.1.7.14 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › CTP-dep_RFKase 0.65 58.0 5.01e-01 100.0% 92.9%
5036890 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.64 44.0 3.95e-01 98.9% 51.2%
3387966 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.64 54.0 5.57e-01 97.8% 97.6%
3988795 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 48.0 4.83e-01 94.4% 80.0%
3266828 2.1.1.4 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Ribosomal_S17 0.64 43.0 3.97e-01 100.0% 54.8%
3365827 256.1.1.6 ↗ a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like › HMA 0.63 38.0 4.66e-01 72.2% 98.2%
3282596 206.1.1.11 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.63 54.0 3.50e-01 92.2% 56.1%
3672433 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.63 56.0 3.94e-01 98.9% 33.8%
4995187 1.1.7.14 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › CTP-dep_RFKase 0.62 56.0 5.12e-01 98.9% 98.3%
3178363 1.1.7.24 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_8 0.62 53.0 5.03e-01 95.6% 91.8%
160389 1.1.5.25 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.62 52.0 4.74e-01 93.3% 75.6%
3929255 1.1.7.10 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Flavokinase 0.62 54.0 4.59e-01 95.6% 62.1%
3340063 256.1.1.0 ↗ a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like 0.61 37.0 4.58e-01 71.1% 100.0%
169881 1.1.5.10 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct 0.60 52.0 4.04e-01 95.6% 71.2%
3614277 4014.1.1.1 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV 0.60 45.0 3.66e-01 92.2% 40.6%
3606816 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.60 42.0 3.93e-01 98.9% 59.1%
3597791 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.60 51.0 3.52e-01 92.2% 46.3%
4527829 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 48.0 4.76e-01 95.6% 83.2%
3365684 306.6.1.0 ↗ a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like 0.60 50.0 4.88e-01 93.3% 83.0%
3594650 4014.1.1.0 ↗ a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase 0.60 45.0 3.79e-01 92.2% 45.6%
4629425 11.1.1.1369 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF1410 0.60 50.0 4.92e-01 94.4% 86.3%
3590667 1.1.5.16 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › MreC 0.60 54.0 4.01e-01 100.0% 72.3%
3601712 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.59 50.0 3.30e-01 92.2% 38.1%
4066625 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.59 52.0 4.66e-01 100.0% 71.5%
4637527 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.59 46.0 4.14e-01 84.4% 65.6%
3417528 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 49.0 3.39e-01 92.2% 43.8%
3662469 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 49.0 3.35e-01 92.2% 41.8%
4956610 4081.1.1.0 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related 0.58 49.0 3.86e-01 91.1% 94.1%
3342763 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.58 49.0 3.44e-01 92.2% 48.3%
3183322 4081.1.1.5 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N 0.58 51.0 3.84e-01 97.8% 96.9%
3707666 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.58 48.0 3.31e-01 92.2% 42.7%
3741663 206.1.1.72 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Pkinase_fungal 0.57 48.0 3.38e-01 92.2% 43.7%
3933470 4081.1.1.5 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N 0.57 50.0 3.81e-01 97.8% 92.1%
3933146 4081.1.1.5 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N 0.57 48.0 3.70e-01 94.4% 91.6%
3266101 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.57 48.0 3.33e-01 92.2% 46.3%
3968097 1.1.5.25 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.57 47.0 4.41e-01 90.0% 77.3%
3595505 4081.1.1.0 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related 0.57 49.0 3.57e-01 96.7% 95.3%
3203958 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.57 48.0 3.25e-01 92.2% 50.9%
3596133 310.3.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.56 42.0 4.08e-01 78.9% 76.0%
4376910 305.1.1.0 ↗ a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase 0.56 47.0 4.65e-01 92.2% 94.7%
3401419 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.56 47.0 3.17e-01 92.2% 40.6%
3300222 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.56 46.0 3.07e-01 91.1% 36.1%
3822737 206.1.1.72 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Pkinase_fungal 0.56 46.0 3.25e-01 91.1% 47.9%
3741395 206.1.1.74 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr 0.55 46.0 3.19e-01 92.2% 50.2%
4013356 4178.1.1.0 ↗ beta sandwiches › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain › Putative glucosidase YicI, C-terminal domain 0.55 42.0 3.52e-01 82.2% 97.5%
4944341 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.55 39.0 3.00e-01 74.4% 52.0%
3922900 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.55 46.0 3.11e-01 92.2% 43.4%
3991153 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.54 48.0 3.38e-01 97.8% 51.9%
3390411 4081.1.1.5 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N 0.54 47.0 3.57e-01 97.8% 89.8%
3739752 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.54 45.0 3.14e-01 92.2% 42.2%
3699284 4081.1.1.5 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N 0.54 46.0 3.47e-01 97.8% 92.9%
3797512 4081.1.1.0 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related 0.54 47.0 3.57e-01 97.8% 94.1%
3497104 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.54 46.0 4.08e-01 96.7% 95.6%
3489332 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.54 45.0 3.88e-01 96.7% 99.4%
3769379 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.54 45.0 3.59e-01 97.8% 71.2%
3273458 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.53 44.0 2.68e-01 93.3% 21.7%
3526133 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.53 44.0 4.04e-01 95.6% 95.2%
3389168 4081.1.1.5 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Peptidase_M1_N 0.53 45.0 3.50e-01 95.6% 94.1%
2634413 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.52 43.0 3.75e-01 91.1% 90.8%
3504105 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.52 44.0 3.92e-01 97.8% 88.6%
3420320 11.1.5.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.52 43.0 3.74e-01 92.2% 74.5%
3722018 11.1.5.7 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › Adap_comp_sub 0.52 43.0 3.85e-01 92.2% 81.5%
3482785 305.1.1.0 ↗ a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase 0.51 43.0 3.40e-01 92.2% 74.6%
5013684 4081.1.1.0 ↗ beta sandwiches › Baculovirus p35 protein-related › Baculovirus p35 protein-related › Baculovirus p35 protein-related 0.50 39.0 3.32e-01 84.4% 89.3%
D3 high residues 833-1000
PDB
Domain cluster: rep: IMGVR_UViG_3300021255_003095-3300021255-Ga0223825_1010595139__D209-342
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 96.7 2.00e-27 93.5% 32.7%
D4 medium residues 2-73_87-159
PDB
D5 medium residues 500-524_555-573_621-688
PDB
Domain cluster: rep: DNA_polymerase__YP_008052566__Phaeocystis_globosa_virus__251749__D724-746_869-928
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 84.6 9.50e-24 64.3% 15.4%
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.80 76.0 6.71e-01 100.0% 90.2%
2bvlA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 42.0 4.76e-01 83.9% 69.8%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 46.0 4.94e-01 93.8% 70.1%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.73 47.0 3.57e-01 79.5% 30.9%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 43.0 4.70e-01 98.2% 72.0%
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.71 49.0 4.79e-01 71.4% 87.1%
8anqA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.71 52.0 4.09e-01 76.8% 39.3%
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.71 41.0 4.95e-01 77.7% 85.5%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.71 48.0 4.90e-01 76.8% 71.3%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.69 46.0 5.13e-01 92.0% 83.5%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 53.0 5.00e-01 87.5% 67.2%
8e9gK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 41.0 4.51e-01 86.6% 72.5%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 46.0 4.91e-01 98.2% 78.6%
1kfdA02 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.67 41.0 5.04e-01 76.8% 95.8%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.67 47.0 3.69e-01 91.1% 35.7%
1f7uA02 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.67 42.0 4.09e-01 97.3% 56.8%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.66 44.0 4.97e-01 70.5% 88.2%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 51.0 5.04e-01 87.5% 77.8%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 39.0 4.57e-01 77.7% 86.7%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.65 42.0 4.63e-01 84.8% 82.8%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.64 40.0 4.39e-01 78.6% 77.8%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 46.0 3.52e-01 77.7% 36.3%
1vs5O00 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.62 39.0 4.32e-01 91.1% 79.5%
4mudC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 44.0 3.47e-01 75.0% 59.1%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.61 42.0 4.07e-01 71.4% 91.3%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.60 42.0 3.92e-01 72.3% 80.0%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 46.0 4.66e-01 98.2% 82.7%
2b1eA02 1.20.1310.30 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › 0.59 42.0 3.85e-01 98.2% 55.0%
4r42A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 53.0 4.35e-01 97.3% 78.1%
1chuA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.57 37.0 4.07e-01 90.2% 83.0%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.57 38.0 3.99e-01 83.9% 73.5%
2xsbA02 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.57 44.0 4.04e-01 98.2% 62.4%
2oh3A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 51.0 4.68e-01 97.3% 91.0%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.56 49.0 4.14e-01 99.1% 93.4%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 49.0 4.35e-01 93.8% 87.8%
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 49.0 4.13e-01 98.2% 89.0%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 49.0 4.44e-01 95.5% 84.0%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 49.0 4.60e-01 94.6% 85.2%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 51.0 4.36e-01 100.0% 67.6%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 47.0 4.63e-01 96.4% 85.2%
5ffdA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 48.0 4.48e-01 96.4% 87.6%
5ux1D00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 48.0 3.94e-01 98.2% 68.0%
3pivA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 42.0 3.77e-01 99.1% 60.9%
2wzkA01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.53 40.0 3.87e-01 98.2% 71.7%
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 48.0 4.25e-01 98.2% 82.8%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.52 46.0 4.37e-01 96.4% 100.0%
5ymrC00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.52 45.0 2.69e-01 92.9% 59.8%
1dpsA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 47.0 4.13e-01 97.3% 78.6%
3chtA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.51 47.0 3.40e-01 99.1% 39.5%
1f5xA00 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.51 45.0 3.72e-01 100.0% 93.3%
4oo2A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.50 44.0 3.62e-01 96.4% 83.5%
ECOD (70)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4958554 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.93 71.0 5.35e-01 78.6% 59.1%
3089539 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.92 72.0 5.10e-01 80.4% 56.7%
3597965 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.92 69.0 5.18e-01 77.7% 46.9%
3993981 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.91 69.0 5.26e-01 77.7% 44.9%
3480546 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.90 69.0 5.05e-01 79.5% 59.2%
4981193 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.90 86.0 6.33e-01 100.0% 62.0%
None — 0.89 85.0 5.13e-01 100.0% 26.9%
3628202 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.89 85.0 5.08e-01 100.0% 25.6%
3558196 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.89 85.0 6.07e-01 100.0% 59.6%
None — 0.89 85.0 5.10e-01 100.0% 27.1%
5005286 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.89 84.0 5.88e-01 99.1% 55.4%
5019480 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.88 84.0 4.97e-01 100.0% 23.6%
5048081 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.88 43.0 5.34e-01 79.5% 73.3%
5025209 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.88 70.0 5.28e-01 82.1% 57.9%
5017083 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.88 83.0 6.06e-01 100.0% 64.1%
4956224 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.87 75.0 5.73e-01 90.2% 64.7%
4972474 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.87 83.0 4.94e-01 100.0% 25.0%
4022366 2484.1.1.161 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.86 81.0 4.91e-01 100.0% 27.2%
3289740 605.1.1.4 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.86 46.0 6.34e-01 82.1% 100.0%
4276636 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.86 81.0 5.62e-01 100.0% 63.9%
4978312 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.85 44.0 5.59e-01 83.0% 82.9%
4972182 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.83 45.0 5.65e-01 95.5% 85.7%
3355429 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.82 47.0 6.09e-01 83.0% 98.5%
3251544 109.4.1.192 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.81 44.0 3.78e-01 82.1% 36.5%
5007621 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.79 50.0 5.44e-01 74.1% 75.8%
4628639 150.1.1.59 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F 0.78 46.0 4.99e-01 84.8% 69.5%
4988222 4044.1.1.0 ↗ alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.78 46.0 5.44e-01 76.8% 83.7%
4551916 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.78 47.0 4.48e-01 80.4% 54.4%
5012651 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.78 47.0 5.37e-01 90.2% 80.0%
5011084 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.77 47.0 5.48e-01 99.1% 85.0%
3773235 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.77 44.0 4.93e-01 98.2% 71.1%
5076876 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.77 46.0 5.42e-01 96.4% 83.7%
3215342 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.76 46.0 5.04e-01 80.4% 72.6%
4105677 150.1.1.59 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F 0.75 45.0 5.01e-01 87.5% 74.4%
4950274 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.74 50.0 5.34e-01 92.0% 77.8%
3221363 5057.1.1.1 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.72 52.0 4.70e-01 74.1% 76.6%
3838 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.72 43.0 4.70e-01 98.2% 72.0%
3707377 604.12.1.73 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF27107 0.72 52.0 5.03e-01 97.3% 67.2%
3662288 5050.1.1.1 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.70 46.0 3.52e-01 100.0% 30.3%
4982649 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.70 46.0 3.80e-01 100.0% 38.9%
5055477 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 48.0 5.72e-01 74.1% 100.0%
3585393 633.7.1.11 ↗ alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like › XK-related 0.68 51.0 4.06e-01 77.7% 81.4%
3586382 601.1.2.4 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.68 47.0 4.93e-01 76.8% 79.0%
4976497 4163.1.1.0 ↗ alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.67 45.0 4.45e-01 96.4% 64.2%
4422869 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.66 48.0 5.12e-01 75.0% 100.0%
4266510 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.66 49.0 5.08e-01 76.8% 100.0%
3482166 5039.1.1.0 ↗ alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like 0.64 47.0 4.13e-01 75.9% 57.2%
3204345 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.64 44.0 3.55e-01 100.0% 37.6%
3487704 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.63 47.0 4.67e-01 86.6% 74.8%
5009707 601.14.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.63 43.0 4.08e-01 87.5% 57.8%
4937862 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.61 47.0 4.81e-01 81.2% 84.5%
5055939 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.60 54.0 4.72e-01 96.4% 86.7%
3717958 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 50.0 3.03e-01 88.4% 28.2%
3447097 603.1.1.99 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.59 49.0 4.96e-01 96.4% 89.1%
3589851 4006.1.1.1 ↗ alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.59 44.0 4.41e-01 77.7% 90.4%
3903860 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.58 53.0 4.85e-01 100.0% 82.8%
3638405 633.21.1.0 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.57 51.0 4.49e-01 97.3% 84.2%
3877415 604.1.1.118 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N 0.57 50.0 4.43e-01 94.6% 71.2%
4949711 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.57 51.0 4.60e-01 93.8% 86.9%
3484910 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.56 50.0 4.92e-01 96.4% 90.0%
5059077 150.1.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin 0.56 51.0 4.44e-01 97.3% 89.4%
4600613 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 46.0 4.38e-01 90.2% 78.5%
3595965 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 50.0 3.47e-01 96.4% 58.2%
4032525 3896.1.1.1 ↗ alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase › CTP_transf_1 0.55 40.0 3.10e-01 75.9% 81.2%
3599095 601.24.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) › FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 0.54 39.0 4.16e-01 75.9% 92.0%
2163536 150.1.2.8 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › MiaE 0.53 47.0 3.89e-01 98.2% 66.3%
3475284 5082.1.1.1 ↗ alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.52 46.0 3.59e-01 95.5% 88.1%
3577229 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 44.0 4.43e-01 96.4% 89.6%
3409131 3930.1.1.0 ↗ alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.51 48.0 4.19e-01 100.0% 75.0%
3512636 3930.1.1.6 ↗ alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › Dicer_PBD 0.51 45.0 4.54e-01 97.3% 91.3%
D6 medium residues 525-554_689-832
PDB
Domain cluster: rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 97.6 1.10e-27 83.9% 24.1%
PF00136.27 DNA_pol_B 26.9 3.00e-06 17.2% 5.7%