Back to structures

DNA_polymerase

Euk-Vir

Neodiprion_abietis_NPV

DNA_polymerase__YP_667860__Neodiprion_abietis_NPV__204507

Identity

Accession:
YP_667860 ↗
Protein ID:
DNA_polymerase
Kingdom:
euk

Quality

74.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 35-110_133-191
PDB
D2 high residues 198-414
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF10108.16 best DNA_pol_B_exo2 37.8 2.30e-09 89.4% 74.5%
PF03104.26 DNA_pol_B_exo1 100.9 1.10e-28 77.9% 73.1%
D3 medium residues 111-132_415-503_548-620
PDB
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.88 25.0 4.82e-01 98.4% 83.9%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.84 24.0 3.30e-01 97.3% 49.0%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.81 26.0 4.17e-01 83.2% 73.3%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.81 23.0 4.24e-01 98.4% 80.3%
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.78 52.0 5.71e-01 88.0% 80.4%
3gnlB02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 27.0 4.68e-01 85.9% 95.6%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.73 23.0 3.96e-01 97.3% 80.3%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 28.0 4.19e-01 84.2% 78.8%
3ha4B00 1.20.58.690 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 27.0 3.40e-01 85.3% 56.7%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.68 34.0 4.33e-01 85.3% 79.1%
2qkwA00 1.20.1270.140 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AvrPto 0.67 22.0 2.96e-01 99.5% 52.5%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.66 33.0 3.84e-01 85.9% 64.4%
1rp3A01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.64 20.0 2.88e-01 97.3% 55.3%
1k90B03 1.20.140.60 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.63 28.0 3.55e-01 85.9% 67.8%
2o8pA00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.62 33.0 3.16e-01 93.5% 43.4%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.62 24.0 3.42e-01 85.3% 72.9%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 29.0 3.80e-01 87.0% 82.4%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.58 25.0 3.44e-01 85.3% 79.5%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.57 23.0 3.60e-01 90.2% 95.8%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 30.0 3.48e-01 100.0% 72.9%
2oh3A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 31.0 3.50e-01 100.0% 75.7%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 31.0 3.41e-01 100.0% 71.4%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 30.0 3.31e-01 100.0% 70.7%
3bh1A02 1.20.1570.10 Mainly Alpha › Up-down Bundle › dip2346 fold › dip2346 domain like 0.51 26.0 3.50e-01 98.4% 90.1%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4565383 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.90 22.0 4.94e-01 73.9% 90.0%
2464385 192.27.1.0 alpha bundles › Long alpha-hairpin › Helical hairpin in putative tRNA methyltransferase › Helical hairpin in putative tRNA methyltransferase 0.86 28.0 5.15e-01 85.9% 92.1%
3795985 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.81 29.0 4.38e-01 85.3% 74.1%
3622515 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.80 25.0 3.87e-01 82.6% 65.9%
3743879 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.76 30.0 4.21e-01 85.3% 72.6%
3742811 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.74 30.0 3.87e-01 85.3% 62.6%
4958744 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 31.0 4.09e-01 83.2% 70.0%
4459896 622.4.1.1 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Blo-t-5 0.70 33.0 4.18e-01 85.3% 72.8%
4958743 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 31.0 3.93e-01 83.2% 68.7%
4942685 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.69 59.0 4.17e-01 88.0% 35.1%
3684974 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.67 64.0 4.24e-01 100.0% 72.9%
3904779 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.67 27.0 3.47e-01 88.0% 62.7%
4970593 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.66 49.0 4.33e-01 76.1% 57.2%
4977369 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.64 48.0 4.23e-01 76.1% 57.2%
4022366 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.64 60.0 4.05e-01 100.0% 72.9%
4997717 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.64 48.0 3.95e-01 77.2% 51.9%
3941051 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.54 33.0 3.46e-01 92.4% 64.7%
3242228 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.51 31.0 3.77e-01 88.0% 92.5%
3478235 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.51 29.0 3.53e-01 85.9% 82.8%
D4 medium residues 504-547_621-658
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1l1oF01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.59 40.0 3.47e-01 70.7% 88.5%
3l4aA00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.56 45.0 4.00e-01 89.0% 69.4%
2kvsA00 1.10.150.260 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › YozE SAM-like 0.52 39.0 3.98e-01 97.6% 81.2%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3690104 4026.1.1.0 a+b three layers › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) › a+b domain in Rap/Ran-GAP (Pfam 02145) 0.58 44.0 3.61e-01 80.5% 86.7%
3381592 2486.1.1.6 a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ACCA 0.56 43.0 2.85e-01 81.7% 69.0%
3769368 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.52 38.0 3.95e-01 97.6% 82.7%
D5 medium residues 735-782_848-893
PDB
Domain cluster: representative
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.74 62.0 5.15e-01 90.4% 98.1%
3iayA07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.72 60.0 5.10e-01 90.4% 96.7%
3v0aB02 1.20.1120.10 Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" 0.69 61.0 4.21e-01 100.0% 95.8%
4fwvA02 1.20.120.1680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.68 48.0 4.27e-01 73.4% 98.5%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.67 49.0 4.63e-01 77.7% 67.2%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.66 48.0 4.66e-01 76.6% 85.8%
2f07B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 55.0 4.40e-01 94.7% 81.1%
3lwjA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 54.0 4.40e-01 95.7% 57.0%
1tgoA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.64 57.0 4.76e-01 100.0% 93.4%
4a64A02 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.63 51.0 4.77e-01 86.2% 83.8%
2ibdA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.63 54.0 4.67e-01 94.7% 76.9%
1txuA01 1.10.246.120 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.63 45.0 4.59e-01 76.6% 92.6%
6i2mB02 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.61 49.0 4.53e-01 87.2% 84.4%
5ejrA01 1.25.40.530 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain 0.61 53.0 4.16e-01 96.8% 87.6%
4me9B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 52.0 4.24e-01 95.7% 60.2%
2ggfA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 52.0 4.71e-01 100.0% 85.4%
1f14A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 41.0 3.31e-01 93.6% 34.7%
1q6aA00 1.10.1240.30 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain 0.59 50.0 4.86e-01 95.7% 86.9%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.59 43.0 4.11e-01 76.6% 93.6%
2xgsB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 36.0 3.99e-01 84.0% 78.1%
4i1eA03 1.25.10.30 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain 0.57 47.0 4.19e-01 91.5% 90.6%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 42.0 3.83e-01 78.7% 88.3%
3e4bA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 50.0 3.34e-01 100.0% 49.6%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.56 41.0 3.76e-01 77.7% 73.4%
2i2oA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 49.0 3.88e-01 100.0% 58.8%
5an3A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 44.0 4.06e-01 90.4% 63.6%
6xssA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 37.0 4.16e-01 87.2% 91.3%
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.56 48.0 4.55e-01 96.8% 80.9%
3s4lA00 1.10.3210.30 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › 0.55 46.0 3.60e-01 90.4% 56.9%
1zu2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 44.0 3.82e-01 90.4% 55.1%
5xdcB01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.55 46.0 4.41e-01 95.7% 80.2%
4gywA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 38.0 3.73e-01 86.2% 65.7%
7tzoA01 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.54 42.0 3.47e-01 83.0% 48.3%
4o6kA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.52 36.0 3.27e-01 72.3% 83.1%
2go7A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.51 30.0 3.42e-01 73.4% 80.6%
2iyvA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 46.0 3.71e-01 100.0% 72.1%
1j8yF01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.51 41.0 4.29e-01 95.7% 97.7%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.50 40.0 3.57e-01 88.3% 89.9%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4297578 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.71 58.0 4.92e-01 88.3% 93.5%
3644241 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.71 51.0 4.66e-01 75.5% 88.8%
3805429 3562.1.1.33 alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › ALMT 0.69 48.0 3.98e-01 71.3% 45.6%
3576407 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.69 51.0 4.76e-01 77.7% 94.8%
5026846 4995.1.1.0 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like 0.67 56.0 5.76e-01 97.9% 96.7%
3276902 109.4.1.1224 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_DOCK9 0.67 59.0 4.26e-01 97.9% 34.1%
3432902 603.1.1.5 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N 0.65 45.0 4.27e-01 72.3% 91.3%
3892495 604.1.1.7 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SR_plectin_7 0.62 45.0 4.22e-01 77.7% 87.5%
3935426 109.4.1.791 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_17 0.61 41.0 4.10e-01 84.0% 67.4%
3335971 109.4.1.1394 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_12 0.60 48.0 3.51e-01 86.2% 43.1%
5030341 3352.1.1.2 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 0.60 53.0 3.47e-01 97.9% 29.1%
3782456 109.24.1.2 alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › DHR-2_Lobe_C 0.59 49.0 4.47e-01 92.6% 93.1%
5041255 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.58 40.0 3.89e-01 88.3% 62.9%
3266082 109.6.1.2 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF,RasGEF_N 0.58 51.0 3.38e-01 100.0% 35.6%
3853606 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.57 40.0 3.70e-01 96.8% 56.7%
4011701 109.4.1.301 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Hid1 0.57 49.0 3.58e-01 100.0% 44.4%
4945373 5001.1.1.79 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › YhhN 0.56 43.0 3.33e-01 83.0% 66.2%
3695500 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.56 49.0 3.24e-01 100.0% 44.6%
4479462 109.4.1.179 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nro1 0.56 45.0 3.62e-01 90.4% 51.0%
5077084 5065.1.1.3 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 0.56 49.0 3.64e-01 94.7% 50.9%
5019542 622.4.1.67 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF5518 0.55 41.0 4.04e-01 78.7% 91.9%
1902251 612.1.1.4 alpha arrays › Retroviral matrix proteins › Retroviral matrix proteins › Retroviral matrix proteins › Gag_p10 0.55 38.0 3.62e-01 74.5% 58.1%
3623710 3277.2.1.1 alpha arrays › Thymine dioxygenase JBP1 DNA-binding domain-like › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › a C-terminal domain in chromodomain helicase DNA-binding protein 1 › CHD1-like_C 0.54 42.0 4.10e-01 90.4% 78.1%
3604847 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 46.0 3.85e-01 96.8% 72.1%
4412477 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.52 40.0 3.71e-01 86.2% 63.2%
3281206 192.29.1.52 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Anthrone_oxy 0.52 41.0 3.60e-01 86.2% 62.8%
3614674 109.4.1.43 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SAC3_GANP 0.52 45.0 3.47e-01 95.7% 47.0%
4003130 524.1.1.1 alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › RabGAP-TBC 0.51 33.0 2.77e-01 96.8% 38.7%
D6 medium residues 783-847
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gv9B06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.82 74.0 5.13e-01 100.0% 42.9%
3iayA07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.80 72.0 5.41e-01 100.0% 42.8%
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.76 68.0 5.09e-01 100.0% 43.1%
4b08A08 3.40.1820.20 Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease H-like motif › B family DNA polymerase, thumb domain, alpha/beta motif 0.76 68.0 6.34e-01 100.0% 88.7%
1tgoA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.74 66.0 4.89e-01 100.0% 40.1%
3qexA06 3.40.1820.10 Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease H-like motif › DnaQ-like 3'-5' exonuclease 0.67 58.0 5.21e-01 100.0% 94.6%
3go5A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.57 47.0 4.67e-01 93.8% 94.3%
1smxA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 45.0 4.17e-01 93.8% 95.4%
4pqxA01 2.40.50.500 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › NigD-like N-terminal OB domain 0.55 42.0 4.14e-01 86.2% 93.2%
2x0nA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 41.0 3.09e-01 86.2% 94.5%
1gd7A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 41.0 3.59e-01 87.7% 68.8%
5l37C00 2.40.50.220 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › EutN/Ccml 0.53 41.0 3.81e-01 86.2% 87.2%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3480544 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.82 74.0 5.46e-01 100.0% 43.6%
3514097 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.82 74.0 5.37e-01 100.0% 41.8%
4674133 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.81 74.0 5.33e-01 100.0% 46.3%
3314223 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.81 73.0 5.44e-01 100.0% 44.4%
3705557 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.81 73.0 5.40e-01 100.0% 46.3%
3167790 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.81 73.0 5.50e-01 100.0% 43.3%
3178384 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.80 72.0 5.15e-01 100.0% 43.8%
3597971 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.80 72.0 5.17e-01 100.0% 37.8%
4025114 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.79 71.0 5.20e-01 100.0% 47.6%
3484038 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.79 72.0 4.95e-01 100.0% 41.0%
3404727 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.79 71.0 5.01e-01 100.0% 37.6%
4547010 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.79 72.0 5.12e-01 100.0% 37.8%
4221968 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.79 71.0 5.06e-01 100.0% 43.8%
3214821 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.78 71.0 5.35e-01 100.0% 47.3%
5002819 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.78 71.0 5.24e-01 100.0% 42.5%
5044378 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.78 71.0 5.31e-01 100.0% 44.7%
4956225 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.77 70.0 5.33e-01 100.0% 46.2%
5035330 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.77 67.0 5.09e-01 100.0% 42.0%
5073668 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.77 69.0 5.26e-01 100.0% 47.6%
5031722 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.77 68.0 5.09e-01 100.0% 41.2%
3797774 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.76 68.0 5.25e-01 100.0% 49.0%
4865217 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.76 68.0 5.25e-01 100.0% 47.2%
3256266 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.76 69.0 4.94e-01 100.0% 41.1%
4884450 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.76 68.0 5.60e-01 100.0% 63.5%
5073477 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.76 69.0 5.20e-01 100.0% 44.0%
5041309 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.76 68.0 5.00e-01 100.0% 39.9%
3932597 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.76 67.0 5.07e-01 100.0% 51.6%
3578105 4969.1.1.2 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb 0.75 67.0 4.62e-01 100.0% 48.6%
4297578 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.75 66.0 5.03e-01 100.0% 43.2%
3520971 4969.1.1.2 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb 0.75 67.0 4.55e-01 100.0% 41.7%
5058883 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.74 66.0 4.95e-01 100.0% 43.2%
3403078 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.73 64.0 4.46e-01 100.0% 34.5%
5048997 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.73 65.0 4.75e-01 100.0% 40.2%
57819 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.73 64.0 4.82e-01 100.0% 41.1%
4978606 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.73 65.0 4.90e-01 100.0% 45.8%
2140410 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.72 63.0 4.70e-01 100.0% 39.5%
4961845 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.71 62.0 4.75e-01 100.0% 42.7%
5035013 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.70 61.0 4.66e-01 100.0% 42.1%
4977733 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.70 61.0 4.71e-01 100.0% 44.0%
3387924 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.56 43.0 3.85e-01 84.6% 76.8%
4261758 2.6.1.1 beta barrels › OB-fold › Staphylococcal nuclease › Staphylococcal nuclease › SNase 0.56 46.0 3.54e-01 95.4% 75.6%
3617468 206.1.1.10 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Choline_kinase 0.53 44.0 2.81e-01 96.9% 29.9%