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DNA_polymerase_catalytic_subunit

Euk-Vir

Human_betaherpesvirus_6A

DNA_polymerase_catalytic_subunit__NP_042931__Human_betaherpesvirus_6A__32603

Identity

Accession:
NP_042931 ↗
Protein ID:
DNA_polymerase_catalytic_subunit
Kingdom:
euk

Quality

85.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 80-136_230-275
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03104.26 best DNA_pol_B_exo1 31.0 2.40e-07 54.4% 18.6%
D2 medium residues 137-229
PDB
CATH (73)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4mz0B05 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.81 54.0 6.28e-01 97.8% 95.5%
2jfdA03 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.81 53.0 6.15e-01 97.8% 93.9%
3tzyA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.77 51.0 5.78e-01 96.8% 90.0%
1fvqA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 51.0 5.68e-01 96.8% 97.2%
4pwuC00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 54.0 5.89e-01 100.0% 97.4%
1p1lA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 58.0 5.63e-01 96.8% 83.3%
2rrnA01 3.30.70.2040 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 55.0 5.75e-01 97.8% 96.4%
1j2vA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 56.0 5.52e-01 96.8% 83.2%
6gdxA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 56.0 5.36e-01 96.8% 79.4%
2f1fA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.67 52.0 5.54e-01 94.6% 97.5%
4e98C00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 56.0 5.40e-01 96.8% 81.9%
4g6vB00 3.30.70.2920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 59.0 5.70e-01 95.7% 93.2%
2yweA03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.67 50.0 5.26e-01 90.3% 89.0%
3ce8A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 52.0 5.34e-01 96.8% 89.9%
4iyqA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 55.0 5.31e-01 96.8% 80.4%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 56.0 5.41e-01 96.8% 81.3%
3pimB00 3.30.1060.10 Alpha Beta › 2-Layer Sandwich › Peptide Methionine Sulfoxide Reductase; Chain A › Peptide methionine sulphoxide reductase MsrA 0.65 54.0 4.40e-01 91.4% 59.9%
7oocE01 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.65 54.0 5.62e-01 92.5% 100.0%
5t9pA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.65 54.0 5.54e-01 100.0% 93.3%
2vfrA04 3.30.70.2520 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 54.0 5.46e-01 92.5% 94.7%
3luyA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.64 51.0 5.22e-01 93.5% 89.9%
2dgvA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 51.0 5.29e-01 100.0% 92.0%
3pm9A03 3.30.70.2190 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 57.0 5.27e-01 100.0% 83.5%
5d4nC00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 51.0 5.02e-01 95.7% 82.7%
2ebeA00 3.30.70.2290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein of unknown function (DUF3208) 0.64 56.0 5.44e-01 98.9% 94.3%
2l48A00 3.30.70.2030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 44.0 4.62e-01 90.3% 78.8%
1cqmA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.63 54.0 5.37e-01 96.8% 93.9%
6wubf01 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.63 52.0 5.23e-01 93.5% 97.9%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.63 49.0 4.06e-01 96.8% 46.7%
7qh2C03 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 46.0 4.93e-01 83.9% 92.3%
1wi8A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 48.0 5.21e-01 88.2% 98.7%
1zavA01 3.30.70.1730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein L10, N-terminal RNA-binding domain 0.62 53.0 4.74e-01 95.7% 75.6%
2mgzA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 50.0 5.07e-01 100.0% 86.2%
2cz4A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 51.0 5.03e-01 93.5% 85.9%
6s6yD02 3.30.70.520 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 54.0 4.64e-01 97.8% 94.7%
5w0hA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 49.0 5.24e-01 95.7% 100.0%
1vk3A01 3.90.650.10 Alpha Beta › Alpha-Beta Complex › Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2 › PurM-like C-terminal domain 0.61 55.0 4.36e-01 100.0% 71.7%
1x5oA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 51.0 5.32e-01 90.3% 100.0%
2rvjA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 53.0 5.26e-01 100.0% 89.8%
2uvaG03 3.30.70.3320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 53.0 5.08e-01 96.8% 82.4%
1b3tA00 3.30.70.390 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Epstein Barr virus nuclear antigen-1, DNA-binding domain 0.61 54.0 4.69e-01 100.0% 68.7%
6lpnA03 3.30.70.2190 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 54.0 5.06e-01 100.0% 89.5%
3ue2A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 52.0 5.37e-01 95.7% 100.0%
2bopA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.60 50.0 5.19e-01 98.9% 98.8%
4mlaA03 3.40.462.10 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › FAD-linked oxidases, C-terminal domain 0.60 49.0 3.73e-01 90.3% 43.5%
2dnlA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 48.0 4.97e-01 87.1% 100.0%
3cedA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.59 48.0 4.79e-01 93.5% 84.7%
8c46A01 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 49.0 4.62e-01 92.5% 100.0%
2rb7A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 50.0 4.77e-01 93.5% 98.1%
4mmoA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 49.0 4.09e-01 93.5% 97.6%
3ramA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 50.0 4.65e-01 96.8% 94.1%
1lqlA02 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.58 46.0 4.46e-01 86.0% 91.3%
6tmfM00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.58 48.0 4.73e-01 93.5% 98.0%
2pokA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 48.0 3.97e-01 93.5% 98.8%
4hvzA02 3.30.70.2970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein of unknown function (DUF541), domain 2 0.57 50.0 4.71e-01 96.8% 97.3%
3bf4A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 49.0 4.81e-01 96.8% 99.0%
1f46B00 3.30.1400.10 Alpha Beta › 2-Layer Sandwich › Cell Division Protein Zipa; Chain: A, › ZipA, C-terminal FtsZ-binding domain 0.56 48.0 4.26e-01 96.8% 89.3%
1cg2A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 47.0 4.46e-01 92.5% 98.2%
4ewtA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 48.0 4.52e-01 96.8% 99.1%
2ftrA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 48.0 4.72e-01 97.8% 94.2%
2xzmJ00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.55 46.0 4.45e-01 93.5% 96.2%
4bbyB04 3.30.70.3450 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 49.0 4.76e-01 100.0% 93.3%
1rjjA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 47.0 4.48e-01 96.8% 85.6%
3tm4A01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.55 48.0 3.89e-01 100.0% 94.7%
1kkhA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.54 44.0 3.90e-01 87.1% 93.1%
2fgeA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.54 46.0 3.46e-01 96.8% 79.2%
2zogA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 46.0 3.83e-01 96.8% 98.9%
3bn7A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 46.0 4.51e-01 97.8% 97.1%
1r6yA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 45.0 4.38e-01 100.0% 98.1%
3e05B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 42.0 3.38e-01 92.5% 63.5%
1l3iA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.50 42.0 3.39e-01 92.5% 62.7%
1iq4A00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.50 43.0 3.57e-01 97.8% 72.6%
5xyiU00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.50 41.0 4.07e-01 92.5% 96.9%
ECOD (92)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3837425 3922.1.1.336 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › POL3_N 0.85 73.0 6.98e-01 90.3% 99.0%
5068716 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.85 61.0 4.08e-01 100.0% 21.6%
3579169 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.83 71.0 6.97e-01 91.4% 100.0%
3715670 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.83 69.0 6.73e-01 88.2% 100.0%
5017082 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.81 75.0 4.94e-01 100.0% 26.2%
3731090 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.77 65.0 6.33e-01 90.3% 99.0%
None 0.76 70.0 4.16e-01 100.0% 56.4%
4671096 304.4.1.54 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Amnionless 0.74 64.0 5.67e-01 93.5% 86.9%
3508551 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.74 64.0 5.84e-01 92.5% 99.2%
3711289 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.74 63.0 6.02e-01 91.4% 100.0%
4554366 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.73 62.0 5.79e-01 91.4% 98.3%
3550113 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.72 60.0 5.40e-01 89.2% 100.0%
3784198 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.70 60.0 5.83e-01 93.5% 99.0%
4937786 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.69 56.0 5.48e-01 93.5% 82.0%
4140821 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.69 57.0 5.52e-01 96.8% 81.0%
5038160 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.68 57.0 5.56e-01 96.8% 84.0%
5015958 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.68 56.0 5.48e-01 96.8% 81.7%
5040667 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.68 56.0 5.50e-01 96.8% 82.5%
4957224 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.68 56.0 5.54e-01 96.8% 85.0%
3250928 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.68 54.0 5.72e-01 92.5% 98.8%
3593784 304.126.1.0 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C 0.67 53.0 5.53e-01 93.5% 94.1%
3413150 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.67 54.0 5.35e-01 88.2% 100.0%
3178234 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.66 55.0 5.64e-01 96.8% 93.3%
3703942 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.66 58.0 5.64e-01 97.8% 99.0%
5052024 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.66 55.0 5.72e-01 90.3% 98.8%
3579336 304.5.1.23 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › V_ATPase_I 0.65 52.0 4.99e-01 97.8% 73.6%
3959355 304.8.1.107 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ALO 0.65 56.0 4.85e-01 94.6% 86.8%
3225950 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.65 52.0 4.76e-01 97.8% 65.8%
1288930 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.65 57.0 5.56e-01 96.8% 100.0%
3484885 304.55.2.0 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.65 56.0 4.91e-01 97.8% 95.9%
3915011 389.1.1.7 few secondary structure elements › EGF-like › EGF-related › EGF/Laminin › EGF_CA 0.65 55.0 4.66e-01 100.0% 55.6%
3191453 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.65 52.0 5.40e-01 92.5% 95.3%
3569962 4323.1.1.1 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.64 51.0 5.13e-01 97.8% 85.3%
4387576 304.5.1.1 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › P-II 0.64 56.0 5.38e-01 96.8% 86.7%
3593420 304.25.1.0 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.64 54.0 5.02e-01 92.5% 99.1%
3719736 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.63 58.0 4.08e-01 98.9% 35.6%
4084990 304.30.1.1 a+b two layers › Alpha-beta plaits › D-ribose-5-phosphate isomerase (RpiA), lid domain › D-ribose-5-phosphate isomerase (RpiA), lid domain › Rib_5-P_isom_A 0.63 51.0 5.34e-01 89.2% 100.0%
3178013 304.9.1.103 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF26763 0.63 57.0 5.59e-01 100.0% 98.0%
3522520 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.62 48.0 5.09e-01 91.4% 96.2%
3729608 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.62 53.0 4.89e-01 96.8% 88.0%
3499556 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.62 57.0 4.16e-01 100.0% 41.3%
4027962 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.62 49.0 4.92e-01 96.8% 85.3%
4201083 304.12.1.1 a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › Ribosomal_S6 0.61 54.0 5.33e-01 97.8% 92.0%
3175163 304.9.1.74 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Nab6_mRNP_bdg 0.61 54.0 5.26e-01 100.0% 86.7%
5202 304.5.1.1 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › P-II 0.61 51.0 5.03e-01 96.8% 86.0%
4167213 304.12.1.1 a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › Ribosomal_S6 0.61 54.0 5.35e-01 100.0% 93.0%
3623510 304.25.1.0 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.61 51.0 5.00e-01 94.6% 94.3%
3662024 304.30.1.1 a+b two layers › Alpha-beta plaits › D-ribose-5-phosphate isomerase (RpiA), lid domain › D-ribose-5-phosphate isomerase (RpiA), lid domain › Rib_5-P_isom_A 0.61 50.0 5.07e-01 89.2% 96.7%
4021596 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.61 53.0 3.87e-01 100.0% 37.0%
3288140 304.44.1.0 a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 0.61 52.0 4.83e-01 96.8% 98.3%
3723193 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.61 56.0 4.62e-01 100.0% 64.4%
3575538 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.61 54.0 5.13e-01 100.0% 94.5%
4028387 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.61 52.0 5.17e-01 98.9% 93.7%
3417210 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.60 50.0 5.08e-01 97.8% 94.4%
3823137 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.60 53.0 4.70e-01 100.0% 93.6%
4451470 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.60 53.0 4.78e-01 100.0% 93.8%
3268891 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.60 55.0 4.00e-01 100.0% 41.6%
4319369 304.8.1.1 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › Thr_dehydrat_C 0.60 48.0 4.95e-01 100.0% 91.1%
3664706 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.59 46.0 4.85e-01 90.3% 90.6%
3555669 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.59 51.0 4.78e-01 97.8% 98.3%
3184391 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.59 52.0 4.95e-01 100.0% 97.3%
3705216 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.59 54.0 4.56e-01 100.0% 70.0%
4133168 304.44.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › PriA_C 0.59 51.0 4.93e-01 95.7% 93.3%
3434827 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.59 49.0 4.56e-01 93.5% 99.2%
3189075 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.59 53.0 4.88e-01 98.9% 81.7%
4034375 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.58 49.0 4.64e-01 93.5% 94.8%
3203084 3468.1.1.0 a+b two layers › HLTF protein HIRAN domain › HLTF protein HIRAN domain › HLTF protein HIRAN domain 0.58 48.0 4.04e-01 90.3% 93.1%
3386604 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.58 48.0 4.54e-01 93.5% 100.0%
5038341 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.57 45.0 4.38e-01 87.1% 85.7%
5019207 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.57 50.0 4.54e-01 97.8% 98.4%
3929632 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.57 52.0 4.98e-01 100.0% 97.1%
3972333 304.25.1.0 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.57 47.0 4.47e-01 93.5% 100.0%
3875700 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.56 43.0 4.55e-01 83.9% 95.0%
3617902 305.1.1.0 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase 0.56 42.0 4.19e-01 81.7% 83.0%
3715728 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 48.0 4.10e-01 98.9% 96.2%
3597235 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.55 48.0 3.89e-01 98.9% 86.4%
3846578 225.1.1.16 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › DUF4554 0.55 44.0 3.79e-01 91.4% 58.1%
3638246 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.54 47.0 4.30e-01 97.8% 87.2%
4993583 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.54 44.0 4.09e-01 100.0% 70.0%
4336917 2003.1.5.179 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 0.54 45.0 3.57e-01 92.5% 65.1%
4022825 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.54 46.0 4.48e-01 97.8% 89.5%
4084908 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.53 44.0 4.55e-01 92.5% 96.7%
None 0.53 44.0 3.49e-01 91.4% 64.4%
4809499 304.109.1.0 a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e 0.53 36.0 3.80e-01 89.2% 80.0%
4538622 2003.1.5.179 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 0.52 43.0 3.44e-01 92.5% 62.5%
5175 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.52 46.0 4.48e-01 100.0% 98.1%
5025539 2003.1.5.179 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 0.52 43.0 3.39e-01 92.5% 62.0%
5000314 882.1.1.3 a+b two layers › Ribosomal protein L5 › Ribosomal protein L5 › Ribosomal protein L5 › Ribosomal_L5_C 0.51 44.0 3.59e-01 100.0% 67.4%
4945568 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.51 38.0 3.35e-01 90.3% 51.7%
None 0.51 41.0 3.31e-01 88.2% 64.9%
4986411 2003.1.5.179 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 0.51 42.0 3.36e-01 92.5% 60.6%
4933369 242.1.1.7 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.50 41.0 3.74e-01 93.5% 65.4%
D3 medium residues 276-432
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03104.26 best DNA_pol_B_exo1 161.9 2.50e-47 100.0% 68.6%
D4 medium residues 571-693
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 180.1 9.80e-53 100.0% 27.2%
D5 medium residues 694-781
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 74.4 1.20e-20 100.0% 18.3%
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gv9B04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.92 87.0 6.45e-01 100.0% 45.2%
3foeA02 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.70 34.0 3.79e-01 93.2% 58.0%
3eoqB02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.66 58.0 4.61e-01 100.0% 80.9%
3hdiA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.65 58.0 4.47e-01 100.0% 74.7%
1hezE00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.61 30.0 3.42e-01 97.7% 62.3%
2g47A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.60 53.0 3.97e-01 100.0% 66.1%
1q2lA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.59 51.0 3.86e-01 100.0% 67.5%
8affD01 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.59 44.0 4.62e-01 100.0% 92.3%
1aroP05 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.58 48.0 3.77e-01 94.3% 55.5%
2lf2A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 45.0 3.63e-01 86.4% 81.7%
2fkcA01 3.40.1350.40 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.56 45.0 4.27e-01 89.8% 83.6%
2lu1A00 3.30.70.2370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 44.0 4.41e-01 88.6% 88.8%
3ix3A00 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.55 38.0 3.21e-01 72.7% 95.1%
4za1C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 40.0 4.03e-01 98.9% 77.2%
3rlfF04 1.10.3720.10 Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like 0.55 48.0 3.57e-01 100.0% 97.4%
6h1bA02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.55 40.0 3.92e-01 97.7% 69.6%
6le1A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.55 39.0 4.31e-01 78.4% 97.1%
2v8qA01 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.54 45.0 4.53e-01 94.3% 94.4%
2k4vA00 3.30.160.370 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Domain of unknown function DUF5064 0.54 39.0 3.57e-01 79.5% 85.6%
2jkgA00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.53 38.0 3.15e-01 77.3% 99.4%
1p5dX04 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.53 43.0 4.27e-01 98.9% 87.1%
2bcqA03 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.53 45.0 4.11e-01 98.9% 86.2%
1nz8A00 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.52 45.0 4.14e-01 98.9% 76.5%
2qdeA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.51 40.0 3.58e-01 88.6% 79.4%
1gcbA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.50 43.0 2.80e-01 95.5% 32.2%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3784383 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 66.0 4.18e-01 100.0% 18.1%
None 0.86 70.0 4.05e-01 100.0% 11.7%
4231530 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.86 69.0 5.11e-01 100.0% 36.1%
4936127 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.72 52.0 5.56e-01 98.9% 89.3%
4975021 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.70 55.0 5.53e-01 100.0% 85.2%
5070214 304.57.1.0 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like 0.70 54.0 5.11e-01 98.9% 69.5%
4959193 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.67 50.0 5.14e-01 92.0% 83.5%
4934098 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.67 50.0 5.06e-01 100.0% 83.5%
3596804 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 53.0 3.95e-01 100.0% 34.8%
5035888 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.64 50.0 5.08e-01 100.0% 89.4%
3713509 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.64 53.0 3.91e-01 100.0% 34.8%
5078624 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.63 53.0 5.03e-01 94.3% 86.7%
3825031 11.1.1.1188 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF2854 0.62 55.0 4.99e-01 100.0% 80.8%
3609636 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.62 54.0 3.83e-01 100.0% 52.1%
4221845 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.62 45.0 4.72e-01 98.9% 86.3%
3787184 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.61 54.0 3.96e-01 100.0% 63.3%
3498405 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.61 53.0 3.96e-01 100.0% 63.3%
3301512 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 51.0 3.84e-01 97.7% 64.2%
3289040 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.60 47.0 4.62e-01 100.0% 78.9%
1824189 327.6.1.3 a+b two layers › Alpha-lytic protease prodomain-like › Fe-S cluster assembly (FSCA) domain-like › Fe-S cluster assembly (FSCA) domain-like › Germane 0.60 52.0 4.47e-01 100.0% 91.3%
3996738 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 52.0 3.81e-01 100.0% 58.5%
3445307 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 52.0 3.88e-01 100.0% 63.3%
3685056 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 52.0 3.84e-01 100.0% 61.6%
3647805 309.1.1.17 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16, Peptidase_M16_C, Peptidase_M16_M, PqqF-like_C_4 0.59 52.0 2.97e-01 100.0% 16.0%
4799073 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.59 47.0 4.63e-01 89.8% 81.6%
4385282 304.9.1.71 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › SNU71_RBD 0.59 50.0 4.32e-01 97.7% 60.7%
3275397 327.5.1.2 a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C 0.58 52.0 4.53e-01 100.0% 97.8%
4116209 304.130.1.1 a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.57 40.0 4.01e-01 94.3% 72.2%
3207719 2002.1.1.262 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › SGT1 0.57 49.0 4.03e-01 100.0% 54.3%
4320111 218.1.1.8 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.56 45.0 4.40e-01 90.9% 98.0%
3896820 304.48.1.83 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › SGT1 0.55 46.0 3.68e-01 100.0% 44.7%
3237519 331.2.1.0 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.54 43.0 4.35e-01 94.3% 88.9%
4255608 195.1.1.1 alpha complex topology › NusB-like › NusB-like › NusB-like › NusB 0.52 42.0 3.51e-01 88.6% 91.8%
4856701 2003.1.2.15 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.52 37.0 3.57e-01 97.7% 65.7%
4870414 304.161.1.1 a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in TMEM16 lipid scramblase › Alpha-beta plait domain in TMEM16 lipid scramblase › Anoctamin_N 0.50 43.0 3.82e-01 100.0% 86.1%
3250882 220.1.1.199 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_NISCH_C 0.50 36.0 3.10e-01 76.1% 93.8%
1117759 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.50 43.0 3.18e-01 100.0% 67.8%
D6 medium residues 814-1011
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 129.2 2.80e-37 83.8% 32.5%
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fxdA06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.86 66.0 7.33e-01 92.9% 96.9%
3iayA07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.85 61.0 6.99e-01 93.4% 96.1%
4qclA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.83 66.0 7.14e-01 93.9% 95.8%
1tgoA05 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.83 61.0 6.62e-01 94.4% 89.2%
2gv9B06 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.82 73.0 7.29e-01 93.9% 98.0%
3k59A07 1.10.132.60 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain 0.79 56.0 6.53e-01 93.9% 100.0%
1qqeA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 25.0 2.22e-01 97.5% 26.7%
3ubkB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 26.0 3.23e-01 93.4% 66.4%
3bqkA02 1.20.1310.20 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Duffy-antigen binding domain 0.52 35.0 3.91e-01 89.9% 86.5%
4ivfA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 28.0 3.57e-01 94.4% 90.5%
1oe8A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 28.0 3.34e-01 94.4% 80.6%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.50 27.0 3.46e-01 93.9% 90.3%
ECOD (57)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4865217 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.88 62.0 7.29e-01 90.4% 98.6%
4982341 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.87 63.0 7.20e-01 94.4% 96.7%
4297578 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.87 63.0 7.10e-01 93.9% 94.2%
5058883 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.86 65.0 7.38e-01 92.9% 99.4%
3705557 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.86 66.0 7.36e-01 93.9% 97.5%
5035330 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.86 60.0 6.90e-01 93.4% 94.0%
3597971 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.85 65.0 6.89e-01 93.4% 86.1%
3167790 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 62.0 7.08e-01 93.4% 97.3%
5044378 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 61.0 7.03e-01 89.4% 96.7%
4547010 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 65.0 6.84e-01 93.4% 86.1%
4977733 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.85 63.0 7.19e-01 90.4% 99.3%
5073477 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 62.0 7.13e-01 90.9% 98.7%
4929241 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 60.0 6.77e-01 93.4% 91.6%
5035013 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 64.0 7.15e-01 92.4% 96.2%
5073668 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.85 61.0 7.12e-01 84.8% 100.0%
4961845 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.84 62.0 7.12e-01 93.4% 98.7%
3169738 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.84 66.0 7.24e-01 97.0% 97.0%
3314223 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.84 65.0 7.20e-01 94.9% 98.1%
3584203 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.84 67.0 7.10e-01 93.9% 92.6%
3256266 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.84 66.0 6.95e-01 93.9% 89.4%
5051936 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.83 62.0 6.83e-01 93.4% 93.1%
4931233 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.83 58.0 6.78e-01 85.9% 96.6%
5041309 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.83 64.0 7.00e-01 93.9% 93.5%
4956225 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.83 58.0 6.83e-01 89.4% 97.2%
3404727 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.83 66.0 6.69e-01 97.0% 83.0%
57819 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.83 61.0 6.74e-01 94.4% 91.4%
3178384 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.83 68.0 7.11e-01 93.4% 90.8%
5027092 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.82 58.0 6.80e-01 90.4% 100.0%
3514097 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.82 65.0 7.01e-01 96.0% 94.1%
3403078 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.82 66.0 6.35e-01 93.9% 74.1%
3480544 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.82 65.0 7.09e-01 95.5% 97.6%
1821876 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.82 73.0 7.29e-01 93.9% 98.0%
4978606 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.81 61.0 6.89e-01 93.4% 98.7%
5031722 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.81 61.0 6.73e-01 98.5% 95.0%
5002819 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.81 62.0 6.84e-01 94.9% 96.9%
5048997 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.81 63.0 6.78e-01 95.5% 92.0%
4959102 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.80 60.0 6.52e-01 94.4% 89.9%
3185070 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.80 66.0 6.91e-01 93.4% 91.4%
4674133 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.80 63.0 6.75e-01 92.9% 91.4%
4221968 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.80 66.0 6.86e-01 93.9% 91.4%
5025210 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.79 57.0 6.55e-01 91.4% 97.3%
4949768 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.79 59.0 6.55e-01 93.9% 95.0%
4939490 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.79 59.0 6.45e-01 92.9% 92.6%
5009174 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.78 60.0 6.65e-01 99.0% 98.1%
5040511 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.77 51.0 5.96e-01 95.5% 94.2%
5069335 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.77 57.0 6.46e-01 93.4% 97.4%
4030147 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.75 65.0 6.63e-01 93.4% 91.3%
3993980 4969.1.1.1 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.75 65.0 6.56e-01 93.9% 90.0%
3484038 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.72 67.0 6.56e-01 96.5% 96.7%
3578105 4969.1.1.2 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb 0.68 60.0 5.80e-01 92.9% 90.0%
3520971 4969.1.1.2 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb 0.67 60.0 5.70e-01 93.4% 81.3%
4507132 4969.1.1.2 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb 0.67 59.0 5.85e-01 93.4% 95.2%
3800764 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.67 59.0 5.73e-01 93.4% 85.5%
4935886 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.65 52.0 5.36e-01 87.9% 90.2%
3731062 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.55 25.0 3.70e-01 91.4% 100.0%
3881582 310.2.1.31 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF4455 0.52 27.0 3.61e-01 89.4% 93.3%
2337262 1189.1.1.1 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop 0.52 22.0 3.10e-01 76.3% 80.4%