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DNA_polymerase_catalytic_subunit
Euk-VirSpheniscid_alphaherpesvirus_1
DNA_polymerase_catalytic_subunit__YP_009342373__Spheniscid_alphaherpesvirus_1__2560777
Identity
- Accession:
- YP_009342373 ↗
- Protein ID:
- DNA_polymerase_catalytic_subunit
- Kingdom:
- euk
Quality
78.4
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Mardivirus›
Spheniscid_alphaherpesvirus_1
TaxID: 2560777
Cluster
View cluster (158 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 143-199_232-290
D2
medium
residues 504-588
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03104.26 best | DNA_pol_B_exo1 | 23.3 | 5.20e-05 | 30.6% | 10.7% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2gv9A03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.98 | 85.0 | 5.94e-01 | 89.4% | 34.4% |
| 3iayA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.94 | 75.0 | 5.34e-01 | 89.4% | 32.9% |
| 4qclA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.90 | 85.0 | 5.75e-01 | 100.0% | 37.6% |
| 1d5aA02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.88 | 82.0 | 5.92e-01 | 100.0% | 40.1% |
| 4fvmA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.85 | 72.0 | 5.08e-01 | 89.4% | 44.0% |
| 1noyB02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.79 | 66.0 | 4.77e-01 | 91.8% | 33.6% |
| 1s5jA02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.78 | 62.0 | 4.61e-01 | 84.7% | 36.6% |
| 2e6mA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.73 | 62.0 | 4.73e-01 | 90.6% | 53.8% |
| 7pbkA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.73 | 67.0 | 4.85e-01 | 100.0% | 50.9% |
| 7sxqA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.72 | 66.0 | 4.64e-01 | 100.0% | 44.8% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 37.0 | 3.79e-01 | 72.9% | 60.5% |
| 1ugoA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.61 | 41.0 | 3.95e-01 | 84.7% | 59.6% |
| 1v4aA01 | 1.10.4050.10 | Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE | 0.55 | 41.0 | 3.77e-01 | 78.8% | 76.1% |
| 8alzB08 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.53 | 40.0 | 3.53e-01 | 82.4% | 77.9% |
| 3v93F01 | 1.10.1300.10 | Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 0.51 | 39.0 | 2.76e-01 | 85.9% | 90.9% |
ECOD (78)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4891100 | 2484.1.1.161 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.98 | 80.0 | 5.32e-01 | 100.0% | 26.5% |
| 1822623 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.98 | 95.0 | 6.29e-01 | 100.0% | 31.0% |
| 3710418 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.94 | 90.0 | 5.62e-01 | 100.0% | 22.7% |
| 3558197 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.94 | 90.0 | 6.19e-01 | 100.0% | 34.7% |
| None | — | 0.94 | 90.0 | 5.63e-01 | 100.0% | 23.3% | |
| 4022366 | 2484.1.1.161 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.94 | 89.0 | 5.14e-01 | 100.0% | 13.4% |
| 3628202 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.94 | 89.0 | 5.11e-01 | 100.0% | 12.8% |
| None | — | 0.94 | 89.0 | 5.13e-01 | 100.0% | 13.4% | |
| 3368695 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.93 | 89.0 | 5.52e-01 | 100.0% | 21.8% |
| None | — | 0.93 | 89.0 | 5.11e-01 | 100.0% | 13.3% | |
| 4972474 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.93 | 89.0 | 5.07e-01 | 100.0% | 12.6% |
| 4981192 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.93 | 85.0 | 5.81e-01 | 100.0% | 32.2% |
| 5081878 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.93 | 85.0 | 5.37e-01 | 100.0% | 22.8% |
| 5023018 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.92 | 74.0 | 5.34e-01 | 85.9% | 33.8% |
| 5025208 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.92 | 84.0 | 5.93e-01 | 100.0% | 35.7% |
| 5069333 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.92 | 84.0 | 5.30e-01 | 100.0% | 21.9% |
| 5005285 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.92 | 86.0 | 6.02e-01 | 100.0% | 35.7% |
| 3683241 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.92 | 86.0 | 5.57e-01 | 100.0% | 26.2% |
| 3466667 | 2484.1.1.161 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.92 | 86.0 | 4.94e-01 | 100.0% | 12.9% |
| 4323378 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.91 | 85.0 | 5.65e-01 | 100.0% | 29.0% |
| 4874454 | 2.1.1.25 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 | 0.91 | 85.0 | 5.77e-01 | 100.0% | 31.7% |
| 4988803 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.91 | 86.0 | 5.34e-01 | 100.0% | 22.3% |
| 5067181 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.91 | 85.0 | 5.28e-01 | 100.0% | 22.4% |
| 5056578 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.90 | 85.0 | 5.65e-01 | 100.0% | 30.2% |
| 3784398 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.90 | 85.0 | 5.84e-01 | 100.0% | 56.9% |
| 1790898 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.90 | 83.0 | 5.67e-01 | 100.0% | 31.0% |
| 3192875 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.90 | 84.0 | 5.10e-01 | 100.0% | 19.0% |
| 3825992 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.90 | 84.0 | 5.85e-01 | 100.0% | 36.4% |
| 5019480 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.90 | 84.0 | 4.81e-01 | 100.0% | 11.7% |
| 4942685 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.90 | 84.0 | 5.09e-01 | 100.0% | 19.2% |
| 4932453 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.90 | 84.0 | 5.49e-01 | 100.0% | 28.7% |
| 4953654 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.90 | 84.0 | 5.42e-01 | 100.0% | 25.9% |
| 3206356 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.90 | 84.0 | 5.23e-01 | 100.0% | 22.8% |
| 3168836 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.90 | 84.0 | 5.77e-01 | 100.0% | 36.1% |
| 3995965 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.89 | 83.0 | 6.30e-01 | 100.0% | 49.2% |
| 4002044 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.89 | 81.0 | 5.26e-01 | 100.0% | 24.4% |
| 4023334 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.89 | 83.0 | 5.61e-01 | 100.0% | 32.9% |
| 3684974 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.89 | 83.0 | 4.80e-01 | 100.0% | 13.8% |
| 4805117 | 2484.1.1.161 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.89 | 83.0 | 5.95e-01 | 100.0% | 41.8% |
| 3256261 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.89 | 83.0 | 5.72e-01 | 100.0% | 33.3% |
| 5029084 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.89 | 83.0 | 5.93e-01 | 100.0% | 40.9% |
| 4504110 | 2484.1.1.197 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 | 0.89 | 83.0 | 5.14e-01 | 100.0% | 21.0% |
| 4958553 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.89 | 76.0 | 5.44e-01 | 91.8% | 35.0% |
| 4452101 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.89 | 83.0 | 5.95e-01 | 100.0% | 39.5% |
| 3404726 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 83.0 | 5.50e-01 | 100.0% | 39.3% |
| 5068716 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 83.0 | 5.40e-01 | 100.0% | 28.4% |
| 3797773 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 82.0 | 5.47e-01 | 100.0% | 30.8% |
| 4282509 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.88 | 83.0 | 4.87e-01 | 100.0% | 15.4% |
| 3496492 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.88 | 82.0 | 5.49e-01 | 100.0% | 35.2% |
| 2801086 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 83.0 | 5.26e-01 | 100.0% | 24.2% |
| 5017082 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 83.0 | 5.29e-01 | 100.0% | 23.9% |
| 5035328 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 83.0 | 5.81e-01 | 100.0% | 39.1% |
| 3794217 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.88 | 81.0 | 4.86e-01 | 100.0% | 17.2% |
| 3471270 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.87 | 82.0 | 5.40e-01 | 100.0% | 28.4% |
| 3705562 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.87 | 80.0 | 4.68e-01 | 100.0% | 13.1% |
| 3932596 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.87 | 80.0 | 5.70e-01 | 100.0% | 36.2% |
| 3683989 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.87 | 81.0 | 5.90e-01 | 100.0% | 42.4% |
| 4502019 | 2484.1.1.197 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 | 0.87 | 81.0 | 5.03e-01 | 100.0% | 20.5% |
| 4649118 | 2484.1.1.197 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 | 0.86 | 81.0 | 5.06e-01 | 100.0% | 22.3% |
| 5054032 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.86 | 81.0 | 5.14e-01 | 100.0% | 24.6% |
| 3266685 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.86 | 81.0 | 4.42e-01 | 100.0% | 7.6% |
| 3798596 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.86 | 81.0 | 5.76e-01 | 100.0% | 39.1% |
| 2958185 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.86 | 80.0 | 5.41e-01 | 100.0% | 38.4% |
| 4879892 | 2.1.1.25 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 | 0.86 | 80.0 | 5.79e-01 | 100.0% | 40.1% |
| 3606428 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.86 | 79.0 | 5.64e-01 | 100.0% | 43.4% |
| 3802227 | 2484.1.1.197 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 | 0.86 | 80.0 | 4.51e-01 | 100.0% | 10.4% |
| 3214818 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.84 | 77.0 | 4.94e-01 | 100.0% | 24.5% |
| 4939488 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.84 | 76.0 | 5.13e-01 | 100.0% | 28.6% |
| 4997716 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.84 | 78.0 | 5.58e-01 | 100.0% | 41.8% |
| 5066483 | 2484.1.1.68 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 | 0.81 | 72.0 | 5.61e-01 | 95.3% | 51.2% |
| 4982659 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.80 | 73.0 | 4.73e-01 | 100.0% | 24.9% |
| 11143 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.80 | 73.0 | 4.68e-01 | 100.0% | 91.2% |
| 4333172 | 2484.1.1.20 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 | 0.74 | 66.0 | 4.94e-01 | 96.5% | 53.5% |
| 3661219 | 2484.1.1.20 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 | 0.74 | 67.0 | 4.90e-01 | 100.0% | 53.8% |
| 4188496 | 2484.1.1.20 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 | 0.71 | 64.0 | 4.91e-01 | 100.0% | 57.9% |
| 4975018 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.71 | 65.0 | 4.89e-01 | 100.0% | 56.4% |
| 4856729 | 2484.1.1.20 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 | 0.63 | 55.0 | 4.62e-01 | 100.0% | 68.4% |
| 3992851 | 193.1.1.3 ↗ | alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like › Ndc80_HEC | 0.55 | 42.0 | 4.09e-01 | 89.4% | 72.6% |
D3
medium
residues 589-626_764-820
Domain cluster:
rep: DNA_polymerase_catalytic_subunit__YP_182359__Gallid_alphaherpesvirus_1__10386__D550-582_678-741
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 70.5 | 1.70e-19 | 63.2% | 12.8% |
D4
medium
residues 710-763
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 49.1 | 5.50e-13 | 100.0% | 11.7% |
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2gv9B04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.95 | 82.0 | 5.34e-01 | 90.7% | 24.9% |
| 4hw0C00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.69 | 47.0 | 3.98e-01 | 72.2% | 57.0% |
| 2co5A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.67 | 46.0 | 3.91e-01 | 72.2% | 64.1% |
| 2zkzC00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.66 | 47.0 | 4.01e-01 | 74.1% | 62.1% |
| 2l02A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.66 | 47.0 | 4.08e-01 | 74.1% | 67.1% |
| 4ldgA00 | 2.170.270.10 | Mainly Beta › Beta Complex › Beta-clip-like › SET domain | 0.65 | 55.0 | 3.66e-01 | 100.0% | 23.6% |
| 7txnA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.64 | 44.0 | 3.70e-01 | 70.4% | 65.6% |
| 4rs8A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.64 | 46.0 | 4.00e-01 | 75.9% | 67.9% |
| 5xyiK00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.64 | 43.0 | 3.76e-01 | 72.2% | 77.8% |
| 5optn00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 43.0 | 3.65e-01 | 72.2% | 79.6% |
| 3qdhA01 | 2.60.40.740 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.63 | 44.0 | 3.19e-01 | 74.1% | 62.8% |
| 4bpe700 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 43.0 | 3.60e-01 | 72.2% | 74.3% |
| 3m8eA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 43.0 | 3.56e-01 | 72.2% | 52.5% |
| 1tbxB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 42.0 | 3.66e-01 | 72.2% | 64.4% |
| 5iceA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 42.0 | 3.51e-01 | 72.2% | 58.4% |
| 2rdpA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 42.0 | 3.21e-01 | 72.2% | 39.3% |
| 2x9zA01 | 2.60.40.740 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.61 | 42.0 | 3.10e-01 | 72.2% | 35.6% |
| 3jamK00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.61 | 41.0 | 3.55e-01 | 72.2% | 77.1% |
| 1fp2A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.61 | 41.0 | 3.49e-01 | 72.2% | 60.4% |
| 6uvuA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.60 | 41.0 | 3.41e-01 | 74.1% | 52.9% |
| 5trdA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.59 | 41.0 | 3.62e-01 | 74.1% | 65.5% |
| 2x49A02 | 3.40.5.40 | Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › FHIPEP family, domain 2 | 0.58 | 38.0 | 3.96e-01 | 79.6% | 77.1% |
| 2v1nA01 | 1.10.10.2030 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DNA/RNA-binding protein Kin17, conserved domain | 0.58 | 40.0 | 3.31e-01 | 72.2% | 66.3% |
| 6hciB00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.57 | 39.0 | 3.28e-01 | 72.2% | 76.8% |
| 3a32A01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.57 | 45.0 | 2.90e-01 | 96.3% | 67.9% |
| 3cj1A02 | 3.30.420.150 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 | 0.57 | 44.0 | 2.88e-01 | 87.0% | 92.4% |
| 2l9dA00 | 3.30.70.2340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF12112 family, DUF3579 | 0.56 | 44.0 | 3.60e-01 | 90.7% | 91.7% |
| 1ymmE01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 39.0 | 3.14e-01 | 75.9% | 86.3% |
| 1s48A04 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.56 | 45.0 | 3.65e-01 | 92.6% | 49.5% |
| 2cwrA00 | 2.60.40.290 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.55 | 38.0 | 3.15e-01 | 72.2% | 41.2% |
| 1xovA03 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.55 | 38.0 | 3.54e-01 | 74.1% | 94.4% |
| 4c9yA00 | 1.10.10.1890 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ska1 microtubule binding domain-like | 0.55 | 42.0 | 3.26e-01 | 83.3% | 43.1% |
| 3od1A01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.55 | 46.0 | 2.91e-01 | 100.0% | 36.6% |
| 6mrc100 | 2.30.33.40 | Mainly Beta › Roll › 10 Kd Chaperonin, Protein Cpn10; Chain O › GroES chaperonin | 0.55 | 44.0 | 3.68e-01 | 90.7% | 92.0% |
| 2ahuA01 | 3.40.1080.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaconate Coenzyme A-transferase › Glutaconate Coenzyme A-transferase | 0.55 | 42.0 | 2.71e-01 | 85.2% | 19.4% |
| 7sz8A02 | 2.60.40.60 | Mainly Beta › Sandwich › Immunoglobulin-like › Cadherins | 0.55 | 39.0 | 3.26e-01 | 75.9% | 52.6% |
| 2n0kA00 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 37.0 | 3.21e-01 | 72.2% | 93.3% |
| 1i94H01 | 3.30.1370.30 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › | 0.54 | 40.0 | 3.62e-01 | 83.3% | 76.9% |
| 4a5pB01 | 3.40.30.60 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › FHIPEP family, domain 1 | 0.54 | 46.0 | 3.59e-01 | 100.0% | 71.2% |
| 3c0wA02 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.53 | 42.0 | 3.55e-01 | 92.6% | 54.4% |
| 6vhyC01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.53 | 42.0 | 2.56e-01 | 94.4% | 12.4% |
| 5nqdA01 | 3.30.200.200 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › | 0.53 | 40.0 | 2.92e-01 | 87.0% | 83.1% |
| 1utaA00 | 3.30.70.1070 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Sporulation related repeat | 0.52 | 36.0 | 3.29e-01 | 74.1% | 58.4% |
| 2j0nB00 | 1.20.1710.10 | Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like | 0.52 | 41.0 | 2.98e-01 | 96.3% | 52.4% |
| 1httA01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.51 | 43.0 | 2.84e-01 | 100.0% | 40.1% |
| 1p3hB00 | 2.30.33.40 | Mainly Beta › Roll › 10 Kd Chaperonin, Protein Cpn10; Chain O › GroES chaperonin | 0.51 | 40.0 | 3.44e-01 | 92.6% | 92.9% |
| 4q5eA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.51 | 40.0 | 3.69e-01 | 92.6% | 94.7% |
| 3h41A02 | 2.30.30.40 | Mainly Beta › Roll › SH3 type barrels. › SH3 Domains | 0.51 | 39.0 | 3.71e-01 | 87.0% | 80.9% |
| 2jllA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.50 | 36.0 | 3.12e-01 | 79.6% | 81.1% |
| 1xviA02 | 3.30.980.20 | Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Putative mannosyl-3-phosphoglycerate phosphatase; domain 2 | 0.50 | 36.0 | 3.03e-01 | 75.9% | 98.9% |
ECOD (73)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2723396 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.98 | 91.0 | 7.77e-01 | 96.3% | 66.7% |
| 3786062 | 1.1.5.10 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct | 0.71 | 48.0 | 3.33e-01 | 70.4% | 58.1% |
| 4977499 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.70 | 48.0 | 3.70e-01 | 72.2% | 52.5% |
| 1109306 | 101.1.2.150 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_45 | 0.69 | 47.0 | 3.91e-01 | 72.2% | 54.1% |
| 5024008 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.69 | 47.0 | 4.08e-01 | 70.4% | 63.7% |
| 4965188 | 101.1.2.943 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF26473 | 0.69 | 48.0 | 3.62e-01 | 72.2% | 56.8% |
| 5036041 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.68 | 47.0 | 3.93e-01 | 74.1% | 58.9% |
| 5079762 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.67 | 47.0 | 4.07e-01 | 74.1% | 65.9% |
| 4935902 | 247.1.1.1 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B | 0.67 | 46.0 | 3.01e-01 | 72.2% | 31.1% |
| 4533897 | 101.1.2.508 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF25872 | 0.67 | 46.0 | 3.34e-01 | 72.2% | 37.3% |
| 5071343 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.67 | 46.0 | 3.80e-01 | 72.2% | 65.3% |
| 5035255 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.66 | 46.0 | 3.85e-01 | 74.1% | 61.1% |
| 4958724 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.66 | 45.0 | 3.69e-01 | 72.2% | 58.1% |
| 4983405 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.66 | 46.0 | 3.31e-01 | 74.1% | 38.0% |
| 4973555 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.66 | 46.0 | 3.27e-01 | 74.1% | 35.3% |
| 4969546 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.66 | 45.0 | 3.99e-01 | 72.2% | 75.0% |
| 3615681 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.66 | 44.0 | 3.52e-01 | 70.4% | 46.4% |
| 4946048 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.66 | 45.0 | 4.04e-01 | 74.1% | 78.8% |
| 4971049 | 101.1.2.55 ↗ | alpha arrays › HTH › HTH › winged helix domain › SMC_ScpB | 0.65 | 46.0 | 4.07e-01 | 74.1% | 70.0% |
| 4956538 | 101.1.2.141 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_24 | 0.65 | 46.0 | 4.15e-01 | 74.1% | 72.0% |
| 4995459 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.65 | 45.0 | 3.55e-01 | 74.1% | 51.7% |
| 4096141 | 101.1.2.31 ↗ | alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha | 0.65 | 45.0 | 3.82e-01 | 72.2% | 58.9% |
| 3703873 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 45.0 | 3.62e-01 | 72.2% | 55.2% |
| 4937458 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 45.0 | 4.09e-01 | 74.1% | 70.7% |
| 3625878 | 101.1.2.154 ↗ | alpha arrays › HTH › HTH › winged helix domain › CDT1_C | 0.65 | 44.0 | 3.58e-01 | 70.4% | 58.0% |
| 3461177 | 101.1.2.88 ↗ | alpha arrays › HTH › HTH › winged helix domain › Dimerisation | 0.65 | 45.0 | 3.71e-01 | 74.1% | 56.0% |
| 3922338 | 101.1.2.512 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF25877 | 0.65 | 44.0 | 3.91e-01 | 72.2% | 77.5% |
| 3439148 | 101.1.2.386 ↗ | alpha arrays › HTH › HTH › winged helix domain › WH_DRP | 0.64 | 44.0 | 3.11e-01 | 72.2% | 38.3% |
| 5081465 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.64 | 44.0 | 3.70e-01 | 74.1% | 54.0% |
| 4244628 | 101.1.2.309 ↗ | alpha arrays › HTH › HTH › winged helix domain › GPAT_C | 0.64 | 44.0 | 3.61e-01 | 72.2% | 71.0% |
| 3180198 | 101.1.2.520 ↗ | alpha arrays › HTH › HTH › winged helix domain › DUF7779 | 0.64 | 44.0 | 3.69e-01 | 72.2% | 64.2% |
| 4955611 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.64 | 44.0 | 3.62e-01 | 74.1% | 57.7% |
| 4980135 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.64 | 44.0 | 3.58e-01 | 74.1% | 59.3% |
| 4951675 | 101.1.2.530 ↗ | alpha arrays › HTH › HTH › winged helix domain › HVO_A0114 | 0.63 | 44.0 | 3.63e-01 | 74.1% | 55.0% |
| 3991819 | 70.3.1.1 ↗ | beta barrels › beta-clip › SET domain-like › SET domain-like › SET | 0.63 | 55.0 | 3.55e-01 | 100.0% | 44.3% |
| 4507561 | 3012.1.1.9 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › SecD_1st | 0.63 | 43.0 | 3.09e-01 | 72.2% | 27.7% |
| 4927156 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 45.0 | 3.75e-01 | 77.8% | 66.0% |
| 3223761 | 320.2.1.0 ↗ | a+b two layers › R3H domain-like › Ribosomal protein S8, N-terminal domain › Ribosomal protein S8, N-terminal domain | 0.63 | 43.0 | 3.68e-01 | 74.1% | 80.9% |
| 4979180 | 101.1.2.37 ↗ | alpha arrays › HTH › HTH › winged helix domain › E2F_TDP | 0.63 | 45.0 | 3.42e-01 | 75.9% | 44.0% |
| 4945179 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 44.0 | 3.26e-01 | 74.1% | 53.1% |
| 4625029 | 101.1.2.88 ↗ | alpha arrays › HTH › HTH › winged helix domain › Dimerisation | 0.62 | 43.0 | 3.54e-01 | 74.1% | 57.1% |
| 4476520 | 101.1.2.309 ↗ | alpha arrays › HTH › HTH › winged helix domain › GPAT_C | 0.61 | 42.0 | 3.57e-01 | 72.2% | 72.6% |
| 5082276 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.61 | 43.0 | 3.65e-01 | 74.1% | 61.1% |
| 3583392 | 101.1.2.506 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_NWD1 | 0.61 | 43.0 | 3.92e-01 | 75.9% | 57.3% |
| 4990704 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.61 | 49.0 | 4.02e-01 | 92.6% | 87.6% |
| 3789594 | 859.1.1.0 ↗ | a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 | 0.61 | 43.0 | 2.90e-01 | 75.9% | 21.9% |
| 3370982 | 101.1.2.82 ↗ | alpha arrays › HTH › HTH › winged helix domain › TBPIP | 0.61 | 42.0 | 3.09e-01 | 72.2% | 39.3% |
| 3374769 | 101.1.2.601 ↗ | alpha arrays › HTH › HTH › winged helix domain › TBPIP, LZ3wCH | 0.61 | 41.0 | 2.82e-01 | 72.2% | 27.1% |
| 3598503 | 2484.1.1.15 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › GDA1_CD39 | 0.61 | 42.0 | 2.75e-01 | 74.1% | 87.7% |
| 4249478 | 2003.1.5.16 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CheR | 0.60 | 42.0 | 2.86e-01 | 74.1% | 21.2% |
| 3394098 | 314.1.1.9 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_His | 0.60 | 41.0 | 2.51e-01 | 74.1% | 20.3% |
| 4939871 | 101.1.2.896 ↗ | alpha arrays › HTH › HTH › winged helix domain › DUF2551 | 0.59 | 41.0 | 3.39e-01 | 72.2% | 56.2% |
| 3743227 | 109.4.1.3071 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, HEAT_EZ, Importin_rep_4, TOR1L1_N, TPR_IMB1, TPR_IPO5 | 0.59 | 42.0 | 2.31e-01 | 74.1% | 5.1% |
| 4968842 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 42.0 | 3.78e-01 | 75.9% | 76.2% |
| 3237847 | 314.1.1.9 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_His | 0.59 | 41.0 | 2.48e-01 | 74.1% | 20.8% |
| 3190723 | 109.4.1.1506 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, HEAT_EZ, Importin_rep_4, Importin_rep_6, TPR_IMB1, TPR_IPO5 | 0.59 | 41.0 | 2.28e-01 | 74.1% | 4.6% |
| 3166601 | 109.4.1.3101 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_EZ, Importin_rep_4, Importin_rep_6, TPR_IMB1 | 0.58 | 41.0 | 2.35e-01 | 75.9% | 6.6% |
| 3625508 | 11.1.5.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › DUF7808 | 0.58 | 44.0 | 3.43e-01 | 87.0% | 59.4% |
| 3222667 | 387.1.1.69 ↗ | few secondary structure elements › omega toxin-like › omega toxin-related › omega toxin-related › DUF7808 | 0.57 | 43.0 | 3.34e-01 | 87.0% | 41.4% |
| 3258337 | 314.1.1.9 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_His | 0.57 | 39.0 | 2.42e-01 | 74.1% | 20.5% |
| 3284140 | 101.1.2.87 ↗ | alpha arrays › HTH › HTH › winged helix domain › PaaX | 0.57 | 40.0 | 3.41e-01 | 74.1% | 60.0% |
| 3897323 | 2484.1.1.15 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › GDA1_CD39 | 0.57 | 39.0 | 2.63e-01 | 74.1% | 80.8% |
| 1142249 | 101.1.2.83 ↗ | alpha arrays › HTH › HTH › winged helix domain › SKA1 | 0.56 | 43.0 | 3.34e-01 | 83.3% | 44.5% |
| 4652896 | 3008.1.1.0 ↗ | a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.56 | 45.0 | 3.83e-01 | 92.6% | 82.1% |
| 3281207 | 101.1.2.136 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_20 | 0.55 | 42.0 | 3.62e-01 | 85.2% | 66.7% |
| 3998716 | 11.1.5.97 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › DUF7808 | 0.55 | 43.0 | 3.42e-01 | 90.7% | 50.4% |
| 3718390 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 37.0 | 3.47e-01 | 77.8% | 73.3% |
| 3683800 | 109.4.1.2662 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, Importin_rep_4, Importin_rep_6, HEAT_GCN1, TPR_IMB1, TPR_IPO5 | 0.53 | 39.0 | 2.15e-01 | 81.5% | 19.5% |
| 3386359 | 1.1.7.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C | 0.53 | 37.0 | 3.09e-01 | 72.2% | 53.7% |
| 4992185 | 3696.1.1.0 ↗ | a+b two layers › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related › DNA helicase UvsW N-terminal a+b domain-related | 0.53 | 38.0 | 3.11e-01 | 70.4% | 60.0% |
| None | — | 0.51 | 42.0 | 2.68e-01 | 100.0% | 35.1% | |
| 5053627 | 601.23.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_III | 0.50 | 38.0 | 2.47e-01 | 87.0% | 73.0% |
| 4208861 | 2004.1.1.224 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › P-loop_SecA | 0.50 | 41.0 | 2.78e-01 | 100.0% | 22.4% |
D5
medium
residues 821-917
Domain cluster:
rep: DNA_polymerase_catalytic_subunit__NP_042931__Human_betaherpesvirus_6A__32603__D694-781
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 90.5 | 1.60e-25 | 100.0% | 20.1% |
D6
medium
residues 1027-1089
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 45.1 | 8.90e-12 | 96.8% | 12.1% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2gv9B06 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.93 | 87.0 | 5.86e-01 | 100.0% | 31.0% |
| 4fxdA06 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.78 | 60.0 | 4.33e-01 | 81.0% | 31.9% |
| 4b08A08 | 3.40.1820.20 | Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease H-like motif › B family DNA polymerase, thumb domain, alpha/beta motif | 0.76 | 59.0 | 5.45e-01 | 85.7% | 65.0% |
| 3n75A03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.55 | 41.0 | 3.08e-01 | 82.5% | 67.1% |
| 3gb0A01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.54 | 40.0 | 2.71e-01 | 82.5% | 73.2% |
| 2vycA03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.53 | 40.0 | 2.89e-01 | 82.5% | 69.5% |
| 1q1gA00 | 3.40.50.1580 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain | 0.51 | 45.0 | 3.02e-01 | 100.0% | 72.0% |
| 5tnvA00 | 3.20.20.150 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes | 0.50 | 38.0 | 2.54e-01 | 84.1% | 99.0% |
ECOD (34)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4844122 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.97 | 67.0 | 5.18e-01 | 71.4% | 37.5% |
| 1821876 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.93 | 87.0 | 5.86e-01 | 100.0% | 31.0% |
| 3597971 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.75 | 56.0 | 3.97e-01 | 85.7% | 27.8% |
| 4547010 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.75 | 56.0 | 3.98e-01 | 85.7% | 27.8% |
| 4931677 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.59 | 45.0 | 4.07e-01 | 84.1% | 91.0% |
| 3727124 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 42.0 | 2.48e-01 | 77.8% | 18.1% |
| 3995458 | 4308.1.1.0 ↗ | a+b complex topology › YbiA-like › YbiA-like › YbiA-like | 0.57 | 43.0 | 3.48e-01 | 84.1% | 71.1% |
| 4365324 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.57 | 43.0 | 3.62e-01 | 82.5% | 72.7% |
| 4325853 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.57 | 43.0 | 3.70e-01 | 84.1% | 77.1% |
| 4061614 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.56 | 44.0 | 3.78e-01 | 87.3% | 77.1% |
| 4321330 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.56 | 43.0 | 3.68e-01 | 84.1% | 77.9% |
| 4160300 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.56 | 42.0 | 3.83e-01 | 84.1% | 92.0% |
| 4928672 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.56 | 42.0 | 3.57e-01 | 84.1% | 75.5% |
| 4133258 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.56 | 42.0 | 3.82e-01 | 84.1% | 90.0% |
| 4168340 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.55 | 42.0 | 3.51e-01 | 84.1% | 72.2% |
| 4104960 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.54 | 38.0 | 3.83e-01 | 76.2% | 95.4% |
| 3603323 | 3016.1.1.2 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 | 0.54 | 38.0 | 4.05e-01 | 74.6% | 100.0% |
| 4388672 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.54 | 39.0 | 3.25e-01 | 81.0% | 83.2% |
| 4187835 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.54 | 40.0 | 3.44e-01 | 84.1% | 75.5% |
| 4649054 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.54 | 41.0 | 3.57e-01 | 84.1% | 74.7% |
| 4412646 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.53 | 37.0 | 3.96e-01 | 76.2% | 98.1% |
| 4588019 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.53 | 41.0 | 3.49e-01 | 87.3% | 73.6% |
| 4230466 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.53 | 39.0 | 3.39e-01 | 84.1% | 79.1% |
| 4962127 | 3016.1.1.2 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_3 | 0.52 | 40.0 | 3.36e-01 | 84.1% | 79.1% |
| 3598389 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.52 | 39.0 | 3.24e-01 | 82.5% | 65.0% |
| 3208110 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.52 | 39.0 | 3.23e-01 | 81.0% | 61.7% |
| 4294741 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.52 | 39.0 | 3.41e-01 | 84.1% | 78.1% |
| 4549024 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.52 | 39.0 | 3.34e-01 | 84.1% | 73.7% |
| 4077862 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.52 | 39.0 | 3.31e-01 | 82.5% | 71.7% |
| 4140424 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.52 | 39.0 | 3.38e-01 | 85.7% | 74.5% |
| 4309893 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.51 | 38.0 | 3.35e-01 | 84.1% | 77.1% |
| 3737809 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.51 | 37.0 | 3.44e-01 | 79.4% | 84.7% |
| 3947088 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.50 | 39.0 | 3.62e-01 | 87.3% | 94.1% |
| 4886138 | 7577.1.1.0 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases | 0.50 | 37.0 | 3.46e-01 | 84.1% | 95.3% |