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DNA_polymerase_catalytic_subunit
Euk-VirCercopithecine_alphaherpesvirus_2
DNA_polymerase_catalytic_subunit__YP_164473__Cercopithecine_alphaherpesvirus_2__10317
Identity
- Accession:
- YP_164473 ↗
- Protein ID:
- DNA_polymerase_catalytic_subunit
- Kingdom:
- euk
Quality
78.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Cercopithecine_alphaherpesvirus_2
TaxID: 10317
Cluster
View cluster (158 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 955-1001
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2gv9B06 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.93 | 86.0 | 5.45e-01 | 100.0% | 23.2% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4891103 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.97 | 91.0 | 6.46e-01 | 100.0% | 38.5% |
| 4844122 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.96 | 90.0 | 6.44e-01 | 100.0% | 39.2% |
| 1821876 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.93 | 86.0 | 5.45e-01 | 100.0% | 23.2% |
| 2732226 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.92 | 84.0 | 5.85e-01 | 100.0% | 33.8% |
| 5042890 | 101.1.2.14 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_5 | 0.55 | 42.0 | 4.04e-01 | 93.6% | 86.4% |
D2
high
residues 1013-1086_1127-1186
Domain cluster:
rep: hypothetical_protein_MpV1_220__YP_004062103__Micromonas_sp._RCC1109_virus_MpV1__880161__D749-876
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 80.3 | 1.90e-22 | 85.8% | 21.2% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2gv9B06 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.94 | 91.0 | 7.68e-01 | 100.0% | 67.0% |
| 4b08A08 | 3.40.1820.20 | Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease H-like motif › B family DNA polymerase, thumb domain, alpha/beta motif | 0.86 | 51.0 | 6.63e-01 | 70.1% | 100.0% |
| 4fxdA06 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.85 | 69.0 | 6.47e-01 | 99.3% | 70.6% |
| 3iayA07 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.85 | 66.0 | 6.32e-01 | 97.8% | 71.1% |
| 4qclA05 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.82 | 70.0 | 6.40e-01 | 100.0% | 70.8% |
| 1tgoA05 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.78 | 62.0 | 5.72e-01 | 100.0% | 67.1% |
| 3k59A07 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.78 | 60.0 | 5.89e-01 | 99.3% | 75.4% |
| 3c3dA02 | 1.10.8.240 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › CofD-like domain | 0.51 | 25.0 | 2.94e-01 | 100.0% | 64.8% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1821876 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.94 | 91.0 | 7.68e-01 | 100.0% | 67.0% |
| 4982341 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.86 | 64.0 | 6.11e-01 | 100.0% | 68.0% |
| 4956225 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.85 | 65.0 | 6.29e-01 | 94.0% | 71.7% |
| 3584203 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.85 | 72.0 | 6.47e-01 | 100.0% | 67.4% |
| 3314223 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.85 | 72.0 | 6.72e-01 | 100.0% | 73.8% |
| 3167790 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.85 | 66.0 | 6.35e-01 | 99.3% | 72.0% |
| 4978606 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.85 | 66.0 | 6.26e-01 | 99.3% | 69.7% |
| 5051936 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.85 | 64.0 | 5.96e-01 | 99.3% | 65.0% |
| 5031722 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.84 | 66.0 | 6.16e-01 | 100.0% | 67.5% |
| 3597971 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.84 | 68.0 | 6.08e-01 | 99.3% | 62.8% |
| 5046396 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.84 | 64.0 | 5.96e-01 | 99.3% | 65.0% |
| 5002819 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.84 | 70.0 | 6.51e-01 | 100.0% | 72.5% |
| 4547010 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.84 | 68.0 | 6.06e-01 | 99.3% | 62.8% |
| 5027092 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.84 | 59.0 | 5.85e-01 | 96.3% | 69.3% |
| 3514097 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.83 | 71.0 | 6.48e-01 | 100.0% | 70.0% |
| 3403078 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.82 | 71.0 | 5.90e-01 | 100.0% | 55.0% |
| 3480544 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.82 | 71.0 | 6.55e-01 | 100.0% | 73.3% |
| 3256266 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.82 | 70.0 | 6.26e-01 | 100.0% | 66.7% |
| 4030147 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.81 | 73.0 | 6.31e-01 | 99.3% | 64.6% |
| 4884450 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.81 | 60.0 | 6.48e-01 | 85.1% | 88.7% |
| 4931233 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.81 | 57.0 | 5.52e-01 | 88.1% | 65.5% |
| 3993980 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.81 | 69.0 | 5.93e-01 | 100.0% | 59.5% |
| 5041309 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.81 | 65.0 | 5.99e-01 | 100.0% | 67.3% |
| 5009174 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.80 | 62.0 | 5.81e-01 | 100.0% | 66.9% |
| 3404727 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.80 | 67.0 | 5.83e-01 | 100.0% | 60.8% |
| 3178384 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.80 | 72.0 | 6.31e-01 | 99.3% | 68.1% |
| 5040511 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.79 | 54.0 | 5.39e-01 | 100.0% | 67.4% |
| 4949768 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.78 | 64.0 | 5.98e-01 | 100.0% | 71.2% |
| 4674133 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.78 | 68.0 | 6.15e-01 | 97.0% | 69.7% |
| 4939490 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.78 | 63.0 | 5.86e-01 | 97.8% | 69.9% |
| 5025210 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.77 | 60.0 | 5.76e-01 | 94.0% | 71.3% |
| 3185070 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.77 | 70.0 | 6.19e-01 | 99.3% | 69.2% |
| 3932597 | 4969.1.1.1 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.75 | 61.0 | 5.77e-01 | 94.8% | 73.5% |
| 3484038 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.72 | 66.0 | 5.60e-01 | 100.0% | 62.4% |
| 4507132 | 4969.1.1.2 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb | 0.71 | 66.0 | 5.58e-01 | 99.3% | 74.8% |
| 3520971 | 4969.1.1.2 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb | 0.70 | 64.0 | 5.21e-01 | 96.3% | 62.6% |
| 3578105 | 4969.1.1.2 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › POL2_thumb | 0.69 | 63.0 | 5.25e-01 | 96.3% | 70.5% |
| 3800764 | 4969.1.1.0 ↗ | alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I | 0.69 | 63.0 | 5.24e-01 | 97.8% | 65.5% |
| 3189629 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.67 | 62.0 | 4.11e-01 | 97.8% | 29.1% |
D3
medium
residues 752-809
Domain cluster:
rep: DNA_polymerase__YP_008052566__Phaeocystis_globosa_virus__251749__D724-746_869-928
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 66.4 | 3.10e-18 | 100.0% | 12.6% |