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DNA_polymerase_catalytic_subunit
Euk-VirHuman_gammaherpesvirus_4
DNA_polymerase_catalytic_subunit__YP_401712__Human_gammaherpesvirus_4__10376
Identity
- Accession:
- YP_401712 ↗
- Protein ID:
- DNA_polymerase_catalytic_subunit
- Kingdom:
- euk
Quality
85.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Lymphocryptovirus›
human_gammaherpesvirus_4
TaxID: 10376
Cluster
View cluster (158 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 86-148_235-280
Domain cluster:
rep: DNA_polymerase_catalytic_subunit__NP_944403__Psittacid_alphaherpesvirus_1__50294__D105-157_257-307
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03104.26 best | DNA_pol_B_exo1 | 34.9 | 1.50e-08 | 48.6% | 18.6% |
D2
high
residues 150-229
Domain cluster:
rep: BALF5__YP_010084701__Lymphocryptovirus_Macaca_pfe-lcl-E3__1716044__D162-229
D3
high
residues 830-1008
Domain cluster:
rep: DNA_polymerase_catalytic_subunit__NP_073324__Meleagrid_alphaherpesvirus_1__37108__D926-999_1042-1063_1105-1149
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 126.6 | 1.70e-36 | 92.2% | 32.2% |
D4
medium
residues 22-85
Domain cluster:
rep: BALF5__YP_010084701__Lymphocryptovirus_Macaca_pfe-lcl-E3__1716044__D18-75
D5
medium
residues 288-457
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03104.26 best | DNA_pol_B_exo1 | 184.1 | 4.20e-54 | 100.0% | 74.0% |
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1d5aA02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.90 | 74.0 | 6.73e-01 | 100.0% | 66.4% |
| 3iayA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.90 | 86.0 | 7.79e-01 | 99.4% | 78.4% |
| 1q8iA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.88 | 73.0 | 7.05e-01 | 98.2% | 77.8% |
| 2gv9A03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.88 | 84.0 | 7.53e-01 | 98.2% | 76.5% |
| 1s5jA02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.80 | 71.0 | 6.74e-01 | 98.2% | 79.9% |
| 1noyB02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.79 | 75.0 | 6.67e-01 | 98.2% | 77.9% |
| 4fvmA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.78 | 74.0 | 6.55e-01 | 100.0% | 77.8% |
| 4qclA03 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.77 | 74.0 | 6.14e-01 | 100.0% | 63.1% |
| 1x9mA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.72 | 52.0 | 4.65e-01 | 97.6% | 55.3% |
| 1wcwA01 | 3.40.50.10090 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 36.0 | 4.09e-01 | 94.1% | 86.4% |
| 3wg9A02 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 37.0 | 4.05e-01 | 97.1% | 86.4% |
| 3e61B01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.53 | 30.0 | 3.68e-01 | 98.2% | 88.5% |
| 4xc7B01 | 3.40.50.280 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain | 0.52 | 36.0 | 3.90e-01 | 95.3% | 84.0% |
| 2pn1A01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 32.0 | 3.62e-01 | 91.8% | 82.9% |
| 1gsoA01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 30.0 | 3.67e-01 | 87.6% | 97.9% |
| 1a6dA03 | 3.50.7.10 | Alpha Beta › 3-Layer(bba) Sandwich › GroEL › GroEL | 0.51 | 28.0 | 2.92e-01 | 94.7% | 57.5% |
| 3lp8A01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.50 | 29.0 | 3.57e-01 | 88.8% | 98.9% |
ECOD (95)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4492006 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.93 | 69.0 | 5.76e-01 | 100.0% | 48.1% |
| 4504110 | 2484.1.1.197 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 | 0.92 | 77.0 | 5.57e-01 | 100.0% | 35.2% |
| 5036329 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.92 | 69.0 | 6.05e-01 | 100.0% | 55.3% |
| 5056578 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.92 | 78.0 | 6.24e-01 | 100.0% | 49.8% |
| 4282509 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.92 | 76.0 | 5.04e-01 | 100.0% | 25.5% |
| 4452101 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.92 | 76.0 | 6.82e-01 | 100.0% | 65.5% |
| 4953654 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.92 | 78.0 | 5.99e-01 | 100.0% | 43.8% |
| 4972474 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.91 | 81.0 | 5.17e-01 | 100.0% | 23.0% |
| 4990754 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.91 | 70.0 | 6.27e-01 | 100.0% | 59.6% |
| 4982659 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.91 | 70.0 | 5.29e-01 | 100.0% | 38.0% |
| 5076410 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.91 | 70.0 | 5.22e-01 | 100.0% | 36.2% |
| 4981192 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.91 | 70.0 | 5.97e-01 | 100.0% | 52.9% |
| 3368695 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.90 | 87.0 | 6.33e-01 | 100.0% | 43.1% |
| 3558197 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.90 | 85.0 | 7.29e-01 | 98.2% | 67.3% |
| 4799493 | 2.1.1.25 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 | 0.90 | 62.0 | 7.40e-01 | 75.3% | 98.3% |
| None | — | 0.90 | 86.0 | 5.51e-01 | 99.4% | 26.1% | |
| None | — | 0.90 | 86.0 | 5.55e-01 | 100.0% | 26.5% | |
| 3628202 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.89 | 86.0 | 5.50e-01 | 100.0% | 25.4% |
| 4022366 | 2484.1.1.161 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.89 | 84.0 | 5.45e-01 | 99.4% | 26.1% |
| 4891100 | 2484.1.1.161 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.89 | 87.0 | 7.18e-01 | 100.0% | 64.9% |
| 5035328 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.89 | 74.0 | 6.46e-01 | 100.0% | 61.7% |
| 5029084 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 76.0 | 6.75e-01 | 100.0% | 66.7% |
| 5067181 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 77.0 | 5.56e-01 | 100.0% | 36.9% |
| None | — | 0.88 | 85.0 | 6.35e-01 | 99.4% | 46.3% | |
| 1822623 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 86.0 | 7.05e-01 | 100.0% | 62.8% |
| 3710418 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.88 | 85.0 | 6.29e-01 | 99.4% | 45.1% |
| 4942685 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.88 | 76.0 | 5.28e-01 | 100.0% | 31.3% |
| 5019480 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.87 | 79.0 | 4.96e-01 | 100.0% | 21.8% |
| 4932479 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.87 | 74.0 | 5.88e-01 | 100.0% | 48.9% |
| 5023018 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.86 | 79.0 | 7.29e-01 | 100.0% | 77.1% |
| 5068716 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.86 | 71.0 | 5.59e-01 | 100.0% | 45.0% |
| 5005285 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.86 | 79.0 | 6.87e-01 | 99.4% | 67.7% |
| 5054032 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.86 | 74.0 | 5.51e-01 | 100.0% | 40.8% |
| 3206356 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.86 | 82.0 | 6.00e-01 | 100.0% | 45.2% |
| 3802227 | 2484.1.1.197 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 | 0.85 | 78.0 | 4.74e-01 | 100.0% | 18.7% |
| 3684974 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.85 | 81.0 | 5.24e-01 | 100.0% | 27.6% |
| 3683989 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.85 | 68.0 | 6.24e-01 | 99.4% | 66.7% |
| 4023334 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.84 | 81.0 | 6.66e-01 | 100.0% | 64.6% |
| 4649118 | 2484.1.1.197 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 | 0.84 | 77.0 | 5.58e-01 | 100.0% | 40.3% |
| None | — | 0.84 | 77.0 | 4.68e-01 | 100.0% | 19.0% | |
| None | — | 0.84 | 76.0 | 4.66e-01 | 98.8% | 19.6% | |
| 3584771 | 2484.1.1.197 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 | 0.84 | 76.0 | 6.13e-01 | 100.0% | 53.9% |
| 3798596 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.84 | 76.0 | 6.80e-01 | 100.0% | 70.7% |
| 3619240 | 304.48.1.59 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_exo1, DNA_pol_B_exo2 | 0.84 | 76.0 | 4.71e-01 | 99.4% | 20.8% |
| 3797773 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.83 | 80.0 | 6.46e-01 | 100.0% | 59.7% |
| 3825992 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.83 | 80.0 | 6.85e-01 | 100.0% | 68.8% |
| 3214818 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.83 | 75.0 | 5.63e-01 | 99.4% | 42.9% |
| 3932596 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.83 | 78.0 | 6.79e-01 | 99.4% | 70.2% |
| 4944521 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.82 | 73.0 | 6.68e-01 | 100.0% | 73.8% |
| 3784398 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.82 | 78.0 | 6.67e-01 | 99.4% | 69.4% |
| 4888481 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.82 | 65.0 | 5.47e-01 | 82.4% | 52.3% |
| 5058881 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.82 | 61.0 | 4.69e-01 | 95.3% | 37.9% |
| 5044376 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.81 | 64.0 | 5.04e-01 | 95.3% | 42.5% |
| 3404726 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.81 | 78.0 | 6.31e-01 | 100.0% | 60.7% |
| 3168836 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.81 | 77.0 | 6.58e-01 | 99.4% | 69.4% |
| 11143 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.80 | 77.0 | 5.73e-01 | 100.0% | 50.1% |
| 3705562 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.80 | 75.0 | 4.85e-01 | 99.4% | 25.3% |
| 3794217 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.80 | 76.0 | 5.20e-01 | 100.0% | 72.6% |
| 4988803 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.80 | 77.0 | 5.62e-01 | 100.0% | 67.3% |
| 5070158 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.79 | 60.0 | 4.65e-01 | 95.3% | 38.8% |
| 3605750 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.79 | 77.0 | 4.62e-01 | 100.0% | 34.6% |
| 4323378 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.79 | 76.0 | 6.15e-01 | 100.0% | 62.8% |
| 5041307 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.79 | 62.0 | 5.24e-01 | 95.3% | 52.7% |
| 3606428 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.79 | 73.0 | 6.42e-01 | 98.8% | 69.8% |
| 3702504 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.79 | 75.0 | 6.08e-01 | 100.0% | 60.3% |
| 3597964 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.78 | 75.0 | 6.01e-01 | 100.0% | 58.4% |
| 3692564 | 2.1.1.25 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 | 0.78 | 75.0 | 5.46e-01 | 100.0% | 43.7% |
| 3266685 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.78 | 76.0 | 4.43e-01 | 100.0% | 26.8% |
| 5028571 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.78 | 67.0 | 5.58e-01 | 100.0% | 55.6% |
| 3492151 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.78 | 75.0 | 5.82e-01 | 100.0% | 57.3% |
| 3167764 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.78 | 75.0 | 5.98e-01 | 100.0% | 60.3% |
| 3193111 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.78 | 74.0 | 5.55e-01 | 100.0% | 47.6% |
| 3256261 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.78 | 72.0 | 6.15e-01 | 98.8% | 64.3% |
| 3192875 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.77 | 74.0 | 5.16e-01 | 100.0% | 69.8% |
| 1790898 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.77 | 73.0 | 6.10e-01 | 100.0% | 62.0% |
| 4029124 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.77 | 72.0 | 6.05e-01 | 97.1% | 63.6% |
| 3496492 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.77 | 74.0 | 6.00e-01 | 100.0% | 60.7% |
| 4874454 | 2.1.1.25 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 | 0.77 | 72.0 | 6.10e-01 | 100.0% | 63.4% |
| 4939488 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.76 | 74.0 | 5.97e-01 | 100.0% | 60.7% |
| 4932453 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.76 | 73.0 | 5.76e-01 | 100.0% | 58.4% |
| 4024811 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.76 | 72.0 | 5.93e-01 | 100.0% | 60.4% |
| 4934764 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.75 | 73.0 | 5.44e-01 | 100.0% | 65.8% |
| 4958553 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.75 | 71.0 | 6.40e-01 | 98.8% | 75.9% |
| 5076614 | 2484.1.1.328 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B | 0.75 | 72.0 | 4.68e-01 | 100.0% | 44.9% |
| 4972218 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.75 | 72.0 | 4.93e-01 | 100.0% | 57.4% |
| 4956223 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.74 | 71.0 | 5.74e-01 | 100.0% | 66.8% |
| 5043498 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.74 | 72.0 | 5.25e-01 | 100.0% | 67.2% |
| 4966854 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.74 | 72.0 | 5.38e-01 | 100.0% | 68.6% |
| 4218318 | 2484.1.1.295 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, RNase_H_2 | 0.74 | 71.0 | 5.55e-01 | 100.0% | 60.6% |
| 5048995 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.74 | 66.0 | 5.00e-01 | 95.3% | 42.9% |
| 3614440 | 2484.1.1.177 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF2779 | 0.72 | 59.0 | 5.34e-01 | 99.4% | 65.3% |
| 5073666 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.69 | 63.0 | 4.89e-01 | 95.3% | 75.5% |
| 5035011 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.67 | 61.0 | 5.37e-01 | 95.3% | 71.1% |
| 4055532 | 7510.1.1.0 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like | 0.52 | 35.0 | 3.56e-01 | 100.0% | 66.3% |
| 3286059 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.50 | 41.0 | 4.12e-01 | 98.2% | 83.4% |
D6
medium
residues 553-564_597-703
Domain cluster:
rep: ORF9__YP_009173887__Felis_catus_gammaherpesvirus_1__1452540__D576-679
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 131.2 | 7.00e-38 | 92.4% | 23.2% |
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.89 | 65.0 | 5.92e-01 | 89.9% | 58.8% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.85 | 39.0 | 5.78e-01 | 78.2% | 94.8% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 44.0 | 3.44e-01 | 88.2% | 26.7% |
| 2r9iA00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.84 | 42.0 | 5.45e-01 | 87.4% | 83.1% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.83 | 41.0 | 4.55e-01 | 86.6% | 59.8% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 44.0 | 5.71e-01 | 88.2% | 87.7% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.82 | 38.0 | 4.80e-01 | 86.6% | 72.0% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 42.0 | 4.78e-01 | 88.2% | 67.0% |
| 2cazC00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.79 | 38.0 | 5.17e-01 | 87.4% | 87.5% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.79 | 43.0 | 4.81e-01 | 88.2% | 67.4% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.79 | 45.0 | 4.10e-01 | 84.9% | 45.0% |
| 1wrdA00 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.78 | 44.0 | 4.85e-01 | 98.3% | 68.4% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.77 | 43.0 | 5.69e-01 | 100.0% | 98.5% |
| 2rkhA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.77 | 41.0 | 5.14e-01 | 100.0% | 82.9% |
| 6xkyA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.76 | 46.0 | 3.88e-01 | 82.4% | 38.5% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.73 | 43.0 | 4.86e-01 | 80.7% | 74.7% |
| 5z7qA00 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.73 | 46.0 | 3.99e-01 | 82.4% | 43.2% |
| 1sg2A00 | 3.30.910.20 | Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain | 0.73 | 45.0 | 4.23e-01 | 79.8% | 52.5% |
| 3vkgB03 | 1.20.58.1120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 | 0.72 | 45.0 | 4.04e-01 | 97.5% | 47.4% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 45.0 | 4.66e-01 | 100.0% | 68.4% |
| 2y1vA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.69 | 36.0 | 3.09e-01 | 80.7% | 32.4% |
| 3rm5B02 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.68 | 38.0 | 3.06e-01 | 87.4% | 28.6% |
| 1ni3A03 | 1.10.150.300 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain | 0.67 | 40.0 | 4.56e-01 | 76.5% | 78.0% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 38.0 | 4.70e-01 | 89.1% | 91.7% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 43.0 | 3.86e-01 | 81.5% | 48.4% |
| 2hh7A00 | 1.20.58.1000 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer | 0.64 | 36.0 | 4.11e-01 | 89.9% | 74.1% |
| 4e6nA02 | 6.10.140.1010 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 36.0 | 4.62e-01 | 89.1% | 100.0% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 45.0 | 3.48e-01 | 84.0% | 36.3% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 35.0 | 3.59e-01 | 88.2% | 56.2% |
| 2wzkA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.58 | 37.0 | 3.71e-01 | 100.0% | 61.4% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 42.0 | 4.22e-01 | 100.0% | 75.4% |
| 4ba0A02 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.52 | 38.0 | 2.74e-01 | 76.5% | 89.4% |
| 3kkbA00 | 1.20.120.880 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain | 0.51 | 40.0 | 3.99e-01 | 83.2% | 100.0% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.51 | 39.0 | 3.85e-01 | 80.7% | 78.5% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.51 | 43.0 | 3.52e-01 | 91.6% | 61.8% |
ECOD (86)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3558196 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.91 | 88.0 | 6.33e-01 | 100.0% | 51.2% |
| None | — | 0.91 | 88.0 | 5.28e-01 | 100.0% | 23.1% | |
| None | — | 0.90 | 87.0 | 5.26e-01 | 100.0% | 23.3% | |
| 3480546 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.90 | 83.0 | 6.15e-01 | 95.8% | 57.7% |
| 3628202 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.89 | 86.0 | 5.16e-01 | 100.0% | 22.0% |
| 3590755 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.88 | 44.0 | 6.37e-01 | 88.2% | 100.0% |
| 5044927 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.88 | 44.0 | 6.36e-01 | 84.9% | 100.0% |
| 4022366 | 2484.1.1.161 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.86 | 82.0 | 5.00e-01 | 100.0% | 23.3% |
| 4965632 | 192.7.1.85 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › DUF4349 | 0.84 | 44.0 | 6.11e-01 | 87.4% | 96.9% |
| 4576287 | 3755.3.1.471 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Paralemmin | 0.84 | 44.0 | 4.00e-01 | 88.2% | 40.6% |
| 4955780 | 3939.1.1.387 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › DUF4349 | 0.83 | 44.0 | 6.07e-01 | 87.4% | 96.9% |
| 4972474 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.83 | 79.0 | 4.77e-01 | 100.0% | 21.5% |
| 3692897 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.83 | 44.0 | 5.56e-01 | 88.2% | 84.0% |
| 3917888 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.83 | 44.0 | 4.52e-01 | 88.2% | 54.8% |
| 3627942 | 3755.4.1.1 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 | 0.83 | 44.0 | 3.79e-01 | 88.2% | 36.0% |
| 1171038 | 3755.3.1.148 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › CT398_CC | 0.83 | 44.0 | 3.66e-01 | 88.2% | 33.0% |
| 3358885 | 604.12.1.8 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT | 0.83 | 41.0 | 5.06e-01 | 86.6% | 73.8% |
| 3290879 | 3922.1.1.155 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF4349 | 0.82 | 44.0 | 5.75e-01 | 87.4% | 90.0% |
| 5005286 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.82 | 78.0 | 5.61e-01 | 100.0% | 48.2% |
| 3996264 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.82 | 44.0 | 3.81e-01 | 88.2% | 37.1% |
| 3089539 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.82 | 76.0 | 5.54e-01 | 97.5% | 55.3% |
| 5035200 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.82 | 44.0 | 5.49e-01 | 88.2% | 84.0% |
| 3414767 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.82 | 42.0 | 5.07e-01 | 85.7% | 75.0% |
| 3945517 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.81 | 43.0 | 4.82e-01 | 88.2% | 66.3% |
| 2814929 | 150.1.1.14 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › EncFtn-like | 0.81 | 42.0 | 5.61e-01 | 86.6% | 91.2% |
| 5050301 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.80 | 46.0 | 5.52e-01 | 96.6% | 82.1% |
| 4446039 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.80 | 42.0 | 5.46e-01 | 88.2% | 88.6% |
| 375927 | 150.1.1.14 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › EncFtn-like | 0.80 | 42.0 | 4.73e-01 | 87.4% | 66.3% |
| 3614078 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.79 | 44.0 | 4.48e-01 | 99.2% | 55.8% |
| 4981193 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.79 | 75.0 | 5.65e-01 | 100.0% | 52.9% |
| 3393443 | 192.29.1.164 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › RRP36 | 0.78 | 43.0 | 4.14e-01 | 100.0% | 48.9% |
| 3985434 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.77 | 43.0 | 5.00e-01 | 100.0% | 74.4% |
| 1506772 | 3812.1.1.1 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E | 0.77 | 44.0 | 5.80e-01 | 99.2% | 98.6% |
| 4531598 | 4970.1.1.14 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › RRP36 | 0.77 | 43.0 | 3.91e-01 | 100.0% | 43.2% |
| 4570960 | 605.1.1.137 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › RRP36 | 0.76 | 44.0 | 3.98e-01 | 100.0% | 43.1% |
| 5025209 | 304.48.1.3 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B | 0.76 | 71.0 | 5.55e-01 | 99.2% | 56.6% |
| 3520611 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.74 | 44.0 | 3.74e-01 | 83.2% | 38.4% |
| 3605450 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.74 | 44.0 | 3.08e-01 | 83.2% | 20.6% |
| 3266812 | 3291.1.1.211 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › EMC3_TMCO1 | 0.73 | 46.0 | 4.13e-01 | 73.1% | 47.5% |
| 3550436 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.73 | 45.0 | 4.86e-01 | 82.4% | 71.2% |
| 4971709 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.73 | 45.0 | 4.17e-01 | 81.5% | 50.3% |
| 3417096 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.73 | 45.0 | 4.73e-01 | 82.4% | 67.3% |
| 3224742 | 3755.3.1.9 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › SH3BP5 | 0.72 | 40.0 | 3.22e-01 | 88.2% | 30.2% |
| 3684015 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.72 | 49.0 | 5.36e-01 | 87.4% | 83.0% |
| 4419515 | 150.1.1.59 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F | 0.70 | 42.0 | 5.07e-01 | 91.6% | 88.7% |
| 3167235 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.69 | 46.0 | 4.13e-01 | 82.4% | 50.6% |
| 3570403 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.67 | 47.0 | 4.63e-01 | 93.3% | 68.0% |
| 3922888 | 109.4.1.889 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_M | 0.67 | 46.0 | 3.74e-01 | 87.4% | 41.0% |
| 2337262 | 1189.1.1.1 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › Trypan_glycop | 0.67 | 44.0 | 4.88e-01 | 88.2% | 82.5% |
| 5081365 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.66 | 48.0 | 4.50e-01 | 75.6% | 83.4% |
| 3763454 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.65 | 46.0 | 4.67e-01 | 83.2% | 71.7% |
| 3766400 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.64 | 46.0 | 4.85e-01 | 100.0% | 80.0% |
| 1822527 | 101.1.2.135 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR_2 | 0.62 | 43.0 | 3.97e-01 | 86.6% | 55.7% |
| 3911171 | 192.7.1.44 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › SHCBP_N | 0.62 | 43.0 | 4.96e-01 | 89.1% | 94.4% |
| 3394272 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 45.0 | 3.92e-01 | 89.9% | 51.4% |
| 3280999 | 101.1.2.135 ↗ | alpha arrays › HTH › HTH › winged helix domain › MarR_2 | 0.61 | 42.0 | 3.79e-01 | 86.6% | 53.5% |
| 3638713 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.61 | 50.0 | 3.27e-01 | 87.4% | 76.6% |
| 4954852 | 101.1.2.136 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_20 | 0.61 | 42.0 | 3.62e-01 | 94.1% | 48.6% |
| 4272021 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.60 | 46.0 | 5.09e-01 | 89.9% | 96.0% |
| 4363487 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.59 | 47.0 | 5.13e-01 | 89.1% | 97.0% |
| 5048590 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.59 | 44.0 | 4.61e-01 | 86.6% | 82.7% |
| 4165448 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.59 | 46.0 | 4.97e-01 | 89.9% | 92.4% |
| 4979981 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.59 | 44.0 | 4.57e-01 | 85.7% | 82.7% |
| 3504474 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.59 | 46.0 | 4.99e-01 | 100.0% | 96.0% |
| 4221982 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.59 | 46.0 | 5.01e-01 | 89.9% | 96.0% |
| 4565398 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.59 | 46.0 | 5.06e-01 | 89.9% | 97.0% |
| 5053066 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.59 | 50.0 | 3.89e-01 | 89.1% | 54.0% |
| 4470423 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.58 | 46.0 | 4.71e-01 | 89.9% | 85.2% |
| 4074458 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.57 | 44.0 | 4.85e-01 | 89.9% | 96.0% |
| 4041347 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.56 | 43.0 | 4.46e-01 | 84.0% | 84.5% |
| 4042986 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.56 | 43.0 | 4.67e-01 | 89.9% | 95.0% |
| 4060910 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.56 | 44.0 | 4.68e-01 | 89.9% | 92.4% |
| 3640083 | 2004.1.1.185 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11,AAA_12 | 0.56 | 44.0 | 3.07e-01 | 82.4% | 31.7% |
| 3733141 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 45.0 | 4.19e-01 | 84.9% | 73.8% |
| 3690329 | 2004.1.1.473 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII, AAA_11 | 0.55 | 43.0 | 3.00e-01 | 82.4% | 30.7% |
| 3724988 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.55 | 43.0 | 2.99e-01 | 82.4% | 31.1% |
| 3212879 | 174.1.1.40 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF5373 | 0.55 | 46.0 | 4.25e-01 | 86.6% | 93.8% |
| 3273491 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.53 | 47.0 | 3.34e-01 | 94.1% | 38.8% |
| 3369775 | 5076.2.1.10 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › PF29520 | 0.52 | 47.0 | 3.59e-01 | 100.0% | 91.6% |
| 3600065 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.52 | 45.0 | 2.92e-01 | 89.9% | 51.5% |
| 4156333 | 109.4.1.206 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › YfiO | 0.52 | 47.0 | 4.33e-01 | 100.0% | 76.0% |
| 3492118 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 48.0 | 3.66e-01 | 100.0% | 71.5% |
| 3497934 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.51 | 43.0 | 3.36e-01 | 89.9% | 68.4% |
| 3591988 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 46.0 | 3.24e-01 | 95.0% | 70.0% |
| 3699638 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.50 | 46.0 | 2.79e-01 | 95.8% | 33.1% |
| 3708624 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.50 | 46.0 | 2.77e-01 | 95.8% | 32.3% |
D7
medium
residues 565-596_704-829
Domain cluster:
rep: NC_042352.1__YP_009639584.1__FGG68_gp42__00043__D422-604
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00136.27 best | DNA_pol_B | 132.5 | 2.70e-38 | 81.0% | 28.0% |
| PF00136.27 | DNA_pol_B | 47.5 | 1.70e-12 | 20.9% | 7.1% |