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DNA_polymerase_processivity_factor
Euk-VirTurkeypox_virus
DNA_polymerase_processivity_factor__YP_009177157__Turkeypox_virus__336486
Identity
- Accession:
- YP_009177157 ↗
- Protein ID:
- DNA_polymerase_processivity_factor
- Kingdom:
- euk
Quality
78.8
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Avipoxvirus›
Turkeypox_virus
TaxID: 336486
Cluster
View cluster (29 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 4-55
Domain cluster:
rep: processivity_factor__YP_009046183__Penguinpox_virus__648998__D4-41
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05941.20 best | Chordopox_A20R | 64.5 | 1.20e-17 | 100.0% | 14.6% |
CATH (42)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4od8D00 | 6.10.140.1880 | Special › Helix non-globular › Helix Hairpins › | 0.92 | 79.0 | 7.98e-01 | 90.4% | 92.2% |
| 3k3oA02 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.85 | 73.0 | 6.14e-01 | 94.2% | 94.0% |
| 1ldjA01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.76 | 59.0 | 4.50e-01 | 86.5% | 73.6% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.74 | 51.0 | 5.26e-01 | 73.1% | 98.0% |
| 4gpkB01 | 1.25.40.1000 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.74 | 53.0 | 4.36e-01 | 78.8% | 41.4% |
| 1r5aA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.73 | 56.0 | 4.16e-01 | 84.6% | 89.0% |
| 2ycdA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.72 | 55.0 | 4.21e-01 | 82.7% | 100.0% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.72 | 54.0 | 4.48e-01 | 84.6% | 52.5% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 52.0 | 4.86e-01 | 76.9% | 70.8% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.70 | 49.0 | 4.62e-01 | 75.0% | 73.4% |
| 1y74A00 | 1.10.287.650 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain | 0.69 | 48.0 | 4.67e-01 | 73.1% | 71.9% |
| 3feyA02 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.68 | 53.0 | 3.64e-01 | 88.5% | 34.9% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.68 | 56.0 | 4.21e-01 | 98.1% | 55.9% |
| 1ka1A01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.67 | 54.0 | 3.59e-01 | 90.4% | 47.9% |
| 4m3oA00 | 1.25.40.820 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Rtr1/RPAP2 domain | 0.67 | 53.0 | 3.93e-01 | 88.5% | 80.7% |
| 2yevA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 46.0 | 4.14e-01 | 73.1% | 63.5% |
| 1sz9C00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.67 | 54.0 | 4.01e-01 | 92.3% | 48.6% |
| 4exjA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 55.0 | 4.23e-01 | 92.3% | 70.2% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.65 | 53.0 | 4.62e-01 | 96.2% | 88.6% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.65 | 54.0 | 4.73e-01 | 98.1% | 88.2% |
| 4b7yD00 | 3.30.40.10 | Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger) | 0.65 | 54.0 | 4.49e-01 | 96.2% | 96.9% |
| 2kd1A00 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.64 | 52.0 | 4.05e-01 | 92.3% | 83.9% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.63 | 51.0 | 4.44e-01 | 92.3% | 92.8% |
| 4agsB04 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 53.0 | 4.01e-01 | 100.0% | 93.2% |
| 2b25A02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.61 | 51.0 | 3.53e-01 | 94.2% | 54.4% |
| 2vqmA00 | 3.40.800.20 | Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain | 0.61 | 53.0 | 3.17e-01 | 100.0% | 48.6% |
| 2iexA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.61 | 41.0 | 4.18e-01 | 71.2% | 70.6% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.61 | 49.0 | 3.93e-01 | 98.1% | 62.2% |
| 3lysA00 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.61 | 51.0 | 4.10e-01 | 96.2% | 89.5% |
| 1jr8A00 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.59 | 47.0 | 3.79e-01 | 88.5% | 52.4% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.59 | 45.0 | 3.28e-01 | 82.7% | 46.9% |
| 4mduA02 | 1.10.220.10 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin | 0.58 | 49.0 | 4.25e-01 | 96.2% | 100.0% |
| 2pbiA02 | 1.10.1240.60 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › | 0.58 | 43.0 | 3.59e-01 | 80.8% | 43.6% |
| 2diwA01 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.57 | 46.0 | 3.54e-01 | 98.1% | 78.7% |
| 1dgfA03 | 1.20.1370.60 | Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › | 0.56 | 43.0 | 3.50e-01 | 90.4% | 78.9% |
| 6f1eA01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.55 | 47.0 | 3.44e-01 | 94.2% | 48.2% |
| 3b4qA00 | 1.10.1200.100 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › conserved protein domain from corynebacterium diphtheriae | 0.55 | 44.0 | 3.73e-01 | 88.5% | 66.7% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.54 | 44.0 | 3.70e-01 | 98.1% | 83.2% |
| 2ds2D01 | 1.10.110.10 | Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins | 0.52 | 41.0 | 4.02e-01 | 86.5% | 91.2% |
| 2dn0A00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.51 | 38.0 | 3.42e-01 | 84.6% | 61.8% |
| 1hlvA02 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.50 | 38.0 | 3.66e-01 | 82.7% | 95.0% |
| 6cy5A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.50 | 42.0 | 3.55e-01 | 94.2% | 59.6% |
ECOD (31)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3928221 | 4.1.1.310 ↗ | beta barrels › SH3 › SH3 › SH3 › PF26050 | 0.86 | 62.0 | 4.44e-01 | 76.9% | 30.7% |
| 2992201 | 6171.1.1.1 ↗ | alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › JHD | 0.85 | 76.0 | 5.83e-01 | 98.1% | 73.6% |
| 3955636 | 604.12.1.106 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PF28475 | 0.84 | 77.0 | 6.67e-01 | 98.1% | 90.7% |
| 3901041 | 109.4.1.791 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_17 | 0.81 | 68.0 | 4.35e-01 | 94.2% | 27.1% |
| 3185412 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.79 | 68.0 | 5.37e-01 | 96.2% | 60.0% |
| 3918052 | 109.3.1.8 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2 | 0.76 | 65.0 | 3.73e-01 | 96.2% | 11.0% |
| 3929910 | 101.1.2.507 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_TANC1 | 0.75 | 63.0 | 4.47e-01 | 94.2% | 43.2% |
| 4012960 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.75 | 62.0 | 4.56e-01 | 94.2% | 66.4% |
| 3788155 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.74 | 61.0 | 4.46e-01 | 94.2% | 59.3% |
| 3747576 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.74 | 61.0 | 4.20e-01 | 92.3% | 30.9% |
| 3265360 | 267.1.1.0 ↗ | a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain | 0.73 | 56.0 | 3.96e-01 | 84.6% | 31.2% |
| 3756605 | 192.18.1.0 ↗ | alpha bundles › Long alpha-hairpin › MxiH-like › MxiH-like | 0.71 | 51.0 | 4.67e-01 | 76.9% | 60.0% |
| 3286960 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.70 | 59.0 | 3.41e-01 | 96.2% | 14.8% |
| 5083776 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.70 | 60.0 | 5.01e-01 | 100.0% | 95.8% |
| 3488061 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 57.0 | 3.75e-01 | 94.2% | 59.6% |
| 3380124 | 109.4.1.1266 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm, ARM_PUB | 0.69 | 56.0 | 3.45e-01 | 96.2% | 29.3% |
| 3415313 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 55.0 | 3.44e-01 | 94.2% | 22.5% |
| 4025103 | 109.4.1.142 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CSN8_PSD8_EIF3K | 0.67 | 53.0 | 4.04e-01 | 94.2% | 40.0% |
| 3926411 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 56.0 | 4.55e-01 | 98.1% | 57.1% |
| 3716223 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 55.0 | 3.79e-01 | 94.2% | 37.3% |
| 3194312 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.66 | 53.0 | 3.47e-01 | 92.3% | 29.4% |
| 3488990 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.65 | 54.0 | 3.93e-01 | 96.2% | 47.7% |
| 3596595 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 52.0 | 3.92e-01 | 96.2% | 40.0% |
| 5022741 | 604.9.1.0 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 | 0.65 | 54.0 | 4.74e-01 | 96.2% | 68.8% |
| 3727603 | 109.4.1.598 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mak10 | 0.63 | 53.0 | 3.50e-01 | 96.2% | 41.7% |
| 3574413 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.61 | 51.0 | 4.30e-01 | 94.2% | 84.4% |
| 3715812 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 47.0 | 3.21e-01 | 90.4% | 76.6% |
| 3424523 | 604.5.1.7 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ALMT | 0.58 | 47.0 | 4.02e-01 | 98.1% | 88.4% |
| 3762669 | 4970.1.1.16 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › TMEM218_N | 0.56 | 40.0 | 3.17e-01 | 75.0% | 38.1% |
| 4026357 | 160.1.1.0 ↗ | alpha superhelices › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase › C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0.56 | 42.0 | 3.15e-01 | 88.5% | 46.5% |
| 3593759 | 568.1.1.0 ↗ | few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related | 0.50 | 43.0 | 3.97e-01 | 100.0% | 84.3% |
D2
high
residues 58-212
Domain cluster:
rep: Salt_Pond_R1_B_H2O_MG_scaffold_1_prodigal-single.1__X__X__00295__D161-347
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05941.20 best | Chordopox_A20R | 150.7 | 7.60e-44 | 100.0% | 45.8% |
D3
high
residues 217-307
Domain cluster:
rep: OP328423.1__UXQ87776.1__X__00032__D51-131
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05941.20 best | Chordopox_A20R | 96.6 | 2.20e-27 | 100.0% | 26.8% |
D4
high
residues 315-432