←Back to structures
DNA_polymerase_processivity_subunit
Euk-VirPapiine_alphaherpesvirus_2
DNA_polymerase_processivity_subunit__YP_443889__Papiine_alphaherpesvirus_2__340907
Identity
- Accession:
- YP_443889 ↗
- Protein ID:
- DNA_polymerase_processivity_subunit
- Kingdom:
- euk
Quality
65.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Papiine_alphaherpesvirus_2
TaxID: 340907
Cluster
View cluster (51 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 34-166
Domain cluster:
rep: DNA_polymerase_processivity_subunit__YP_009342361__Spheniscid_alphaherpesvirus_1__2560777__D21-149
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02282.22 best | Herpes_UL42 | 98.5 | 5.00e-28 | 99.2% | 94.2% |
D2
medium
residues 194-281
Domain cluster:
representative
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1dmlA00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.83 | 61.0 | 4.20e-01 | 100.0% | 25.1% |
| 2ix2A01 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.75 | 50.0 | 3.67e-01 | 100.0% | 27.1% |
| 4omfB02 | 3.10.450.750 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.65 | 30.0 | 4.02e-01 | 77.3% | 83.0% |
| 4fvaC00 | 3.60.10.10 | Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase | 0.64 | 46.0 | 3.31e-01 | 73.9% | 68.5% |
| 2inbA00 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.64 | 45.0 | 4.03e-01 | 75.0% | 82.8% |
| 4fpvB00 | 3.60.10.10 | Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase | 0.64 | 45.0 | 3.25e-01 | 73.9% | 79.0% |
| 1wduB00 | 3.60.10.10 | Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase | 0.63 | 44.0 | 3.30e-01 | 71.6% | 83.6% |
| 2oap101 | 3.30.450.380 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.62 | 43.0 | 3.29e-01 | 73.9% | 63.6% |
| 3ajvC02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.61 | 41.0 | 4.12e-01 | 77.3% | 67.0% |
| 2z0lA00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.60 | 50.0 | 3.44e-01 | 100.0% | 26.5% |
| 3uuwB02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.60 | 44.0 | 3.46e-01 | 76.1% | 65.2% |
| 3hslX00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.60 | 52.0 | 3.56e-01 | 100.0% | 28.6% |
| 1ixrA01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.58 | 30.0 | 3.39e-01 | 96.6% | 65.1% |
| 6hrgA00 | 3.60.15.10 | Alpha Beta › 4-Layer Sandwich › Metallo-beta-lactamase; Chain A › Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | 0.56 | 45.0 | 3.35e-01 | 88.6% | 100.0% |
| 2cxxA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 40.0 | 3.24e-01 | 77.3% | 89.1% |
| 4rrfA01 | 3.50.80.10 | Alpha Beta › 3-Layer(bba) Sandwich › D-tyrosyl-trna(Tyr) Deacylase; Chain: A; › D-tyrosyl-tRNA(Tyr) deacylase | 0.55 | 38.0 | 3.32e-01 | 72.7% | 89.7% |
| 3d31A02 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.54 | 26.0 | 3.28e-01 | 95.5% | 80.4% |
| 4nq3A01 | 3.30.1330.170 | Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Cyanuric acid hydrolase/Barbiturase, RU A | 0.54 | 40.0 | 3.92e-01 | 79.5% | 90.8% |
| 3w5xA00 | 3.30.70.1350 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain | 0.54 | 37.0 | 3.87e-01 | 71.6% | 100.0% |
| 1tltA02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.53 | 39.0 | 3.19e-01 | 79.5% | 68.8% |
| 6b10A00 | 3.75.10.10 | Alpha Beta › 5-stranded Propeller › L-arginine/glycine Amidinotransferase; Chain A › L-arginine/glycine Amidinotransferase; Chain A | 0.53 | 46.0 | 3.20e-01 | 98.9% | 55.2% |
| 4c81A00 | 3.30.1330.50 | Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 0.53 | 39.0 | 3.32e-01 | 79.5% | 93.6% |
| 1ml8A02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.53 | 37.0 | 3.60e-01 | 71.6% | 97.9% |
| 4rr9A01 | 3.50.80.10 | Alpha Beta › 3-Layer(bba) Sandwich › D-tyrosyl-trna(Tyr) Deacylase; Chain: A; › D-tyrosyl-tRNA(Tyr) deacylase | 0.53 | 37.0 | 3.26e-01 | 72.7% | 89.6% |
| 2j5vB01 | 3.40.1160.10 | Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like | 0.53 | 44.0 | 3.38e-01 | 96.6% | 93.1% |
| 4bubA02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.52 | 36.0 | 2.71e-01 | 71.6% | 72.2% |
| 1r85A00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.51 | 38.0 | 2.55e-01 | 78.4% | 62.8% |
| 1alo006 | 3.30.365.10 | Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain | 0.51 | 36.0 | 3.31e-01 | 76.1% | 83.3% |
| 2fltA00 | 3.30.429.10 | Alpha Beta › 2-Layer Sandwich › Macrophage Migration Inhibitory Factor › Macrophage Migration Inhibitory Factor | 0.50 | 38.0 | 3.54e-01 | 83.0% | 93.2% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 71028 | 227.1.1.5 ↗ | a+b two layers › DNA clamp › DNA clamp › DNA clamp › Herpes_UL42 | 0.79 | 62.0 | 5.29e-01 | 100.0% | 55.0% |
| 3930634 | 246.3.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos | 0.65 | 46.0 | 3.31e-01 | 73.9% | 68.1% |
| 1203297 | 246.3.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos | 0.64 | 46.0 | 3.31e-01 | 73.9% | 68.5% |
| 4928711 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.64 | 46.0 | 4.27e-01 | 75.0% | 84.5% |
| 3174811 | 2008.2.1.2 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › Sen15 | 0.62 | 45.0 | 4.09e-01 | 78.4% | 77.2% |
| 141372 | 2008.2.1.1 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo | 0.61 | 41.0 | 4.11e-01 | 77.3% | 67.0% |
| 3943562 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.61 | 44.0 | 3.97e-01 | 77.3% | 76.8% |
| 1082804 | 227.1.1.13 ↗ | a+b two layers › DNA clamp › DNA clamp › DNA clamp › Herpes_DNAp_acc | 0.60 | 50.0 | 4.22e-01 | 100.0% | 54.1% |
| 11040 | 2008.1.1.32 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › XisH | 0.60 | 44.0 | 3.92e-01 | 77.3% | 83.7% |
| 5027537 | 316.1.1.27 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Polbeta | 0.60 | 41.0 | 3.68e-01 | 72.7% | 78.5% |
| 5064069 | 2008.2.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like | 0.59 | 35.0 | 3.68e-01 | 70.5% | 63.7% |
| 4932970 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.59 | 42.0 | 4.03e-01 | 76.1% | 81.0% |
| 4983181 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.58 | 43.0 | 3.87e-01 | 77.3% | 68.3% |
| 4009644 | 2008.1.1.160 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27151 | 0.58 | 42.0 | 3.45e-01 | 77.3% | 52.0% |
| 4982246 | 3521.1.1.0 ↗ | a+b three layers › Polymerase basic protein 2 cap-binding domain › Polymerase basic protein 2 cap-binding domain › Polymerase basic protein 2 cap-binding domain | 0.58 | 41.0 | 3.97e-01 | 73.9% | 86.0% |
| 5063524 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.57 | 40.0 | 3.27e-01 | 71.6% | 39.6% |
| 4090404 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.57 | 41.0 | 3.86e-01 | 77.3% | 75.5% |
| 4968936 | 2008.1.1.4 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Cas_Cas4 | 0.56 | 39.0 | 3.01e-01 | 72.7% | 46.0% |
| None | — | 0.56 | 41.0 | 3.86e-01 | 78.4% | 92.0% | |
| 4937815 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.56 | 40.0 | 4.21e-01 | 76.1% | 87.5% |
| 2389853 | 2.11.1.1 ↗ | beta barrels › OB-fold › Antifungal protein (AGAFP) › Antifungal protein (AGAFP) › Antifungal_prot | 0.55 | 29.0 | 3.36e-01 | 87.5% | 71.9% |
| 4008023 | 2.1.1.332 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF30333 | 0.55 | 39.0 | 3.86e-01 | 100.0% | 69.5% |
| 5072012 | 2008.1.1.3 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc | 0.55 | 37.0 | 3.74e-01 | 77.3% | 68.9% |
| 5002918 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.55 | 39.0 | 4.06e-01 | 76.1% | 98.8% |
| 4052436 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.55 | 38.0 | 2.80e-01 | 71.6% | 69.8% |
| 4992470 | 896.1.1.0 ↗ | a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related | 0.54 | 32.0 | 3.83e-01 | 95.5% | 88.3% |
| 3394261 | 327.11.1.4 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › MRP-S24 | 0.54 | 37.0 | 3.29e-01 | 71.6% | 73.3% |
| 4929635 | 2002.3.1.2 ↗ | a/b barrels › TIM beta/alpha-barrel › Glycoside hydrolase/deacetylase › Glycoside hydrolase/deacetylase › Polysacc_deac_1 | 0.54 | 46.0 | 3.52e-01 | 98.9% | 89.8% |
| 3851420 | 327.11.1.4 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) › MRP-S24 | 0.54 | 39.0 | 3.51e-01 | 78.4% | 70.0% |
| 5028076 | 316.1.1.2 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 | 0.53 | 41.0 | 3.59e-01 | 86.4% | 87.6% |
| 4002275 | 2003.1.5.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr | 0.53 | 44.0 | 2.87e-01 | 93.2% | 65.9% |
| 4028488 | 224.1.1.0 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like | 0.53 | 44.0 | 3.80e-01 | 92.0% | 77.1% |
| 5071430 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.53 | 36.0 | 3.62e-01 | 70.5% | 85.6% |
| 4045472 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.53 | 37.0 | 3.90e-01 | 75.0% | 100.0% |
| 1718745 | 3186.1.1.1 ↗ | a+b two layers › C-terminal domain of FliK › C-terminal domain of FliK › C-terminal domain of FliK › Flg_hook | 0.53 | 36.0 | 3.59e-01 | 71.6% | 74.5% |
| 3642904 | 246.3.1.0 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like | 0.53 | 37.0 | 2.75e-01 | 73.9% | 56.5% |
| 3989293 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.52 | 37.0 | 3.48e-01 | 76.1% | 79.1% |
| 3275560 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.52 | 45.0 | 3.54e-01 | 100.0% | 87.8% |
| 3787053 | 224.1.1.1 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF | 0.52 | 43.0 | 3.75e-01 | 92.0% | 85.0% |
| 4063004 | 2.1.1.84 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Prot_ATP_ID_OB_N | 0.51 | 28.0 | 2.45e-01 | 89.8% | 30.0% |
| 4111759 | 2.1.1.84 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Prot_ATP_ID_OB_N | 0.51 | 28.0 | 2.46e-01 | 89.8% | 31.1% |
| 4360803 | 3939.1.1.324 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › Prot_ATP_ID_OB_N | 0.51 | 28.0 | 2.46e-01 | 89.8% | 31.1% |
| 8831 | 2002.1.1.18 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_10 | 0.51 | 38.0 | 2.55e-01 | 78.4% | 62.8% |
| 5021191 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.51 | 43.0 | 3.74e-01 | 94.3% | 87.9% |
| 4177859 | 2.1.1.84 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Prot_ATP_ID_OB_N | 0.51 | 27.0 | 3.02e-01 | 90.9% | 63.1% |
| 5014625 | 301.2.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › PurM N-terminal domain-like › PurM N-terminal domain-like › AIRS | 0.51 | 39.0 | 3.43e-01 | 84.1% | 69.3% |