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DNA_repair_exonuclease

Euk-Vir

Pithovirus_sibericum

DNA_repair_exonuclease__YP_009001061__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001061 ↗
Protein ID:
DNA_repair_exonuclease
Kingdom:
euk

Quality

84.8 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Pithoviridae› Alphapithovirus› Pithovirus_sibericum

TaxID: 1450746

Cluster

View cluster (51 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-236
PDB
Domain cluster: rep: IMGVR_UViG_3300020369_000079-3300020369-Ga0211709_100073652__D2-241
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00149.34 best Metallophos 52.1 1.60e-13 79.5% 99.5%
D2 medium residues 241-297
PDB
Domain cluster: representative
CATH (86)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xggB00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.80 71.0 5.22e-01 100.0% 95.9%
6tgvA01 3.40.50.1950 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like 0.80 71.0 4.97e-01 100.0% 48.0%
1xmxA01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.79 71.0 5.24e-01 100.0% 43.0%
1p3y100 3.40.50.1950 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavin prenyltransferase-like 0.76 67.0 4.76e-01 100.0% 43.3%
4f1jA00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.76 67.0 4.58e-01 100.0% 72.0%
4uulA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.76 66.0 4.88e-01 100.0% 46.1%
1u8xX01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.75 65.0 4.71e-01 100.0% 41.0%
1jqdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.75 66.0 4.19e-01 100.0% 23.1%
1vjtA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.75 66.0 5.26e-01 100.0% 60.3%
4g6uA02 3.40.1350.110 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.74 65.0 4.92e-01 100.0% 65.9%
1up7A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.74 64.0 4.91e-01 100.0% 47.4%
2w9hA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.73 51.0 3.70e-01 100.0% 26.8%
3qyfA01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.73 64.0 4.61e-01 100.0% 49.1%
6xl1A01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.73 62.0 4.54e-01 96.5% 41.9%
2g9zA02 3.40.50.10240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin pyrophosphokinase, catalytic domain 0.73 62.0 4.42e-01 96.5% 99.4%
3hv8A00 3.20.20.450 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain 0.72 63.0 4.13e-01 100.0% 30.6%
7d73E01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.71 59.0 3.99e-01 94.7% 35.9%
3no3A00 3.20.20.190 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphatidylinositol (PI) phosphodiesterase 0.71 60.0 4.02e-01 100.0% 44.1%
6r8gA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.70 59.0 4.46e-01 96.5% 43.0%
2wteA01 3.40.50.11700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.70 59.0 4.49e-01 96.5% 46.4%
8g64A01 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.70 60.0 4.38e-01 100.0% 41.6%
4ombA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.69 45.0 3.25e-01 73.7% 24.7%
1cqxA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.69 59.0 4.50e-01 100.0% 45.1%
3ab8A00 3.40.50.12370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.69 58.0 3.84e-01 100.0% 34.1%
3qivA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.69 57.0 4.06e-01 100.0% 84.4%
1u3dA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.69 58.0 4.24e-01 96.5% 77.6%
4u63A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.68 59.0 4.24e-01 100.0% 71.8%
1qydA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.68 58.0 4.11e-01 100.0% 31.4%
5wt3A03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.68 58.0 4.15e-01 100.0% 32.6%
2bpoA04 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.68 58.0 4.26e-01 100.0% 44.4%
2d4aD01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.67 55.0 4.22e-01 94.7% 42.6%
2uyoA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.67 59.0 3.78e-01 100.0% 21.5%
1tq8A00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.67 58.0 4.57e-01 100.0% 52.8%
1o94A03 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.67 58.0 4.32e-01 100.0% 52.0%
3fz0D00 3.90.245.10 Alpha Beta › Alpha-Beta Complex › Inosine-uridine Nucleoside N-ribohydrolase; Chain A › Ribonucleoside hydrolase-like 0.67 57.0 3.60e-01 100.0% 19.6%
4dqlA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.67 57.0 4.21e-01 100.0% 42.9%
4kigA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.66 56.0 4.00e-01 96.5% 31.5%
1foaA01 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.66 57.0 3.89e-01 100.0% 29.1%
3c4aA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.66 56.0 3.85e-01 98.2% 28.7%
1yb2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.65 55.0 3.75e-01 100.0% 26.1%
3dlcA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.65 57.0 3.87e-01 100.0% 26.0%
1gvhA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.65 54.0 4.21e-01 100.0% 45.8%
2esrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.65 56.0 4.12e-01 100.0% 36.3%
4s1wB01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.65 55.0 3.87e-01 100.0% 42.1%
2ljaA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.65 56.0 4.15e-01 100.0% 42.8%
5bxyA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.65 56.0 4.15e-01 100.0% 37.7%
2cx6A00 3.30.370.10 Alpha Beta › 2-Layer Sandwich › Barnase; Chain D › Barstar-like 0.65 53.0 4.68e-01 96.5% 100.0%
3gjzA02 3.50.30.60 Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › LD-carboxypeptidase A C-terminal domain-like 0.64 54.0 3.96e-01 100.0% 39.1%
1o97D01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.64 53.0 3.82e-01 100.0% 33.9%
2p11A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.64 55.0 4.15e-01 100.0% 42.1%
4pcaB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 52.0 3.65e-01 100.0% 27.1%
2dumC00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.63 51.0 4.02e-01 100.0% 58.2%
2o57A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 54.0 3.96e-01 100.0% 34.5%
1nv8A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 54.0 3.79e-01 100.0% 28.9%
3busB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 53.0 3.58e-01 100.0% 24.0%
7wm5A01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 52.0 3.66e-01 100.0% 27.5%
4pneA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 54.0 3.51e-01 100.0% 21.5%
3e7pA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 53.0 3.53e-01 100.0% 23.3%
4c4aA03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 53.0 4.06e-01 100.0% 39.6%
5c0oH00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 51.0 3.59e-01 100.0% 28.0%
2gpyB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 51.0 3.69e-01 100.0% 30.2%
1uirA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 51.0 3.44e-01 100.0% 24.5%
3lpmA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 51.0 3.56e-01 100.0% 26.5%
2uz0A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.61 51.0 3.45e-01 100.0% 36.8%
5fcdA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 51.0 3.49e-01 100.0% 25.4%
3ntvA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 50.0 3.53e-01 100.0% 27.6%
5i45A00 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.61 50.0 3.61e-01 100.0% 35.9%
2h00B00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 50.0 3.53e-01 100.0% 27.6%
1fuiA01 3.40.50.1070 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 50.0 3.70e-01 100.0% 36.6%
4n7bA03 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.60 48.0 4.26e-01 100.0% 84.5%
1xfdA02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 49.0 3.30e-01 100.0% 45.9%
2cmgA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.59 49.0 3.46e-01 100.0% 33.6%
3kxpA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 50.0 3.28e-01 100.0% 49.6%
3bjrA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.59 48.0 3.29e-01 100.0% 49.6%
3egcD02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 49.0 3.88e-01 100.0% 71.3%
3k6kA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 50.0 3.21e-01 100.0% 40.4%
2ex2A02 3.50.80.20 Alpha Beta › 3-Layer(bba) Sandwich › D-tyrosyl-trna(Tyr) Deacylase; Chain: A; › D-Ala-D-Ala carboxypeptidase C, peptidase S13 0.58 47.0 4.07e-01 100.0% 75.7%
2hu8A02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 47.0 3.19e-01 100.0% 41.4%
4rgyA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 46.0 3.22e-01 100.0% 43.0%
3u0vA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 45.0 3.18e-01 96.5% 57.2%
1lw7A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 46.0 3.53e-01 100.0% 93.0%
2h1iA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 45.0 3.25e-01 100.0% 45.3%
4hxfB02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 46.0 3.08e-01 100.0% 42.3%
3qh4A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 47.0 3.02e-01 100.0% 37.6%
5lstA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 46.0 3.21e-01 98.2% 61.4%
2d5lA02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.55 45.0 3.06e-01 100.0% 34.1%
ECOD (91)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3282238 7564.1.1.1 ↗ a/b three-layered sandwiches › Homo-oligomeric flavin-containing Cys decarboxylases, HFCD › Homo-oligomeric flavin-containing Cys decarboxylases, HFCD › Homo-oligomeric flavin-containing Cys decarboxylases, HFCD › Flavoprotein 0.77 68.0 4.94e-01 100.0% 47.5%
3462772 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.76 67.0 4.32e-01 100.0% 25.8%
1177645 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.76 67.0 4.87e-01 100.0% 90.4%
4975997 300.1.1.0 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.75 66.0 4.95e-01 100.0% 47.1%
4013928 2003.1.5.8 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Ubie_methyltran 0.75 65.0 4.13e-01 100.0% 23.2%
1700636 2008.1.1.73 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › CDI_toxin_EC869_like 0.74 65.0 4.83e-01 100.0% 61.5%
4134001 7516.1.1.0 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases 0.74 64.0 4.27e-01 100.0% 28.3%
3850285 7516.1.1.6 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_8 0.73 64.0 3.97e-01 100.0% 23.7%
3741588 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.73 63.0 3.94e-01 100.0% 21.5%
3778602 2006.1.6.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.73 64.0 3.76e-01 100.0% 30.9%
5035891 7542.1.1.7 ↗ a/b three-layered sandwiches › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain › PF28406 0.73 64.0 5.06e-01 100.0% 53.3%
4009283 2004.1.1.196 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_22 0.73 63.0 4.54e-01 100.0% 53.5%
4022820 7514.1.1.6 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › PF26733 0.72 63.0 4.45e-01 100.0% 35.6%
5074968 2008.1.1.122 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DpnII-MboI 0.72 62.0 4.68e-01 100.0% 49.0%
3722663 7514.1.1.0 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain 0.72 61.0 4.86e-01 100.0% 46.7%
5033859 7542.1.1.7 ↗ a/b three-layered sandwiches › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain › Aconitase iron-sulfur domain › PF28406 0.72 62.0 4.83e-01 98.2% 50.0%
4968859 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.72 62.0 4.85e-01 100.0% 53.6%
3271070 2008.1.1.12 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Rad10 0.71 62.0 4.70e-01 100.0% 54.3%
5063199 7592.1.1.6 ↗ a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › Csa3_N 0.71 63.0 4.75e-01 100.0% 44.4%
4027084 2006.1.6.12 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA_2 0.71 61.0 4.24e-01 96.5% 75.1%
4635042 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.71 61.0 3.94e-01 100.0% 27.9%
3592491 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.70 58.0 4.69e-01 96.5% 54.2%
4611335 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.70 60.0 3.68e-01 100.0% 16.3%
2010233 7590.1.1.2 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Piwi 0.70 61.0 4.28e-01 100.0% 57.0%
5000255 7516.1.1.1 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase 0.70 59.0 3.88e-01 96.5% 33.2%
4000201 2005.1.1.36 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.70 60.0 4.64e-01 100.0% 51.9%
3511061 2005.1.1.36 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.70 59.0 4.41e-01 100.0% 44.4%
3587108 2005.1.1.72 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › PF30635 0.70 59.0 4.55e-01 100.0% 44.3%
4073364 2005.1.1.38 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CTU2 0.70 59.0 3.77e-01 100.0% 23.2%
3432581 2003.1.5.31 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GRAS 0.69 58.0 3.57e-01 100.0% 18.0%
4505863 7514.1.1.1 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1 0.69 60.0 4.41e-01 100.0% 44.3%
3691191 7514.1.1.3 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_6 0.69 58.0 4.29e-01 100.0% 52.7%
3415120 7516.1.1.180 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Fringe, Glyco_transf_7C, CHGN 0.69 60.0 3.40e-01 100.0% 11.5%
5064542 2004.1.1.86 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › FeoB_N 0.69 60.0 4.13e-01 100.0% 30.7%
3676379 2005.1.1.36 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.69 59.0 4.02e-01 100.0% 32.3%
141683 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.69 58.0 4.66e-01 98.2% 57.3%
3476281 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.69 57.0 4.53e-01 100.0% 56.2%
3175561 7514.1.1.0 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain 0.69 59.0 4.33e-01 100.0% 39.4%
3265697 7516.1.1.2 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.68 58.0 3.83e-01 100.0% 25.5%
4944920 7516.1.1.26 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_tranf_2_3 0.67 57.0 3.61e-01 100.0% 20.6%
4310954 7512.1.1.8 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Epimerase_2 0.67 57.0 3.95e-01 100.0% 30.0%
5028036 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.67 57.0 4.01e-01 98.2% 34.4%
1890392 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.67 58.0 3.76e-01 100.0% 21.7%
3181264 7514.1.1.0 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain 0.67 56.0 4.18e-01 100.0% 53.3%
3673420 7514.1.1.1 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1 0.67 57.0 5.01e-01 100.0% 65.6%
5014341 2003.1.5.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Met_10 0.67 57.0 3.72e-01 100.0% 21.8%
3319917 7512.1.1.0 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase 0.67 56.0 3.71e-01 100.0% 25.4%
3506929 2005.1.1.36 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.67 57.0 3.61e-01 100.0% 22.9%
3744746 2007.1.3.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.67 55.0 4.26e-01 100.0% 45.5%
3929132 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 55.0 4.21e-01 100.0% 48.0%
4971796 2007.2.1.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › FMN_red 0.66 56.0 3.95e-01 100.0% 40.0%
3726293 2003.1.5.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.66 55.0 3.69e-01 100.0% 24.1%
1174447 2005.1.1.34 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › CCC_C_1st_pro 0.65 56.0 4.49e-01 100.0% 99.2%
168791 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.65 57.0 3.87e-01 100.0% 26.0%
4999512 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.65 56.0 3.83e-01 100.0% 26.0%
4965730 2005.1.1.0 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.65 56.0 4.37e-01 100.0% 50.0%
4943213 2007.6.1.5 ↗ a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.65 56.0 3.96e-01 100.0% 48.7%
3695332 7514.1.1.0 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain 0.65 54.0 4.05e-01 96.5% 92.2%
None — 0.65 54.0 3.65e-01 100.0% 24.1%
4996429 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.65 54.0 3.88e-01 98.2% 33.7%
3838755 2003.1.5.32 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Cons_hypoth95 0.64 55.0 3.85e-01 100.0% 31.8%
4810433 2003.1.5.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 0.64 55.0 3.57e-01 100.0% 20.8%
4476434 2007.6.1.5 ↗ a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › bact-PGI_C 0.64 54.0 3.98e-01 100.0% 54.8%
5053468 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 54.0 3.85e-01 100.0% 54.3%
4026458 2003.1.5.17 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_5 0.64 52.0 3.64e-01 100.0% 26.6%
3185571 7514.1.1.3 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_6 0.63 53.0 3.90e-01 98.2% 94.6%
5051896 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.63 54.0 3.72e-01 100.0% 32.4%
9383 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.63 54.0 3.49e-01 100.0% 20.2%
4001523 2005.1.1.36 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.63 54.0 4.20e-01 100.0% 97.0%
4033345 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.63 54.0 3.59e-01 100.0% 23.0%
None — 0.63 53.0 4.09e-01 100.0% 95.0%
5054857 2002.1.1.83 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_1 0.63 52.0 3.25e-01 100.0% 15.1%
4964385 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.63 53.0 3.73e-01 98.2% 29.7%
169558 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.63 52.0 3.49e-01 100.0% 23.2%
137226 2003.1.5.201 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25, Methyltransf_31 0.63 53.0 3.50e-01 100.0% 23.2%
5012555 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.62 52.0 3.62e-01 100.0% 27.0%
3916793 2005.1.1.36 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.62 51.0 3.80e-01 100.0% 39.4%
4878797 2003.1.5.152 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 0.62 51.0 3.58e-01 100.0% 26.9%
3573985 7516.1.1.35 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Branch 0.62 51.0 3.54e-01 100.0% 30.2%
3713777 7516.1.1.0 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases 0.61 52.0 3.23e-01 100.0% 16.3%
2596039 2003.1.1.28 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › TrkA_N 0.61 51.0 4.07e-01 100.0% 74.6%
4988583 2003.1.5.209 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF29244 0.61 50.0 3.82e-01 100.0% 37.4%
3586113 2005.1.1.36 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.60 49.0 3.55e-01 100.0% 35.4%
4410551 7514.1.1.1 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1 0.60 48.0 3.61e-01 98.2% 95.4%
3719622 7516.1.1.2 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.60 49.0 3.13e-01 96.5% 17.9%
3500954 2005.1.1.36 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.60 41.0 3.05e-01 73.7% 27.4%
3705873 7516.1.1.0 ↗ a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases 0.59 48.0 3.42e-01 96.5% 29.3%
3580315 2005.1.1.36 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › SLC12 0.58 47.0 3.52e-01 100.0% 89.4%
5044268 7579.1.1.3 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9 0.57 48.0 3.16e-01 100.0% 35.6%
3426937 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.55 44.0 2.67e-01 100.0% 11.9%
None — 0.55 46.0 3.21e-01 100.0% 47.6%