DNA_replication_origin-binding_helicase

Euk-Vir

Equid_alphaherpesvirus_4

DNA_replication_origin-binding_helicase__NP_045270__Equid_alphaherpesvirus_4__10331

Identity

74.5 mean pLDDT

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Equid_alphaherpesvirus_4

TaxID: 10331

View cluster (36 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 77-163_177-262

PDB

Domain cluster: rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02399.22 best	Herpes_ori_bp	273.7	4.60e-81	100.0%	22.7%

D2 high residues 267-434_542-567

PDB

Domain cluster: rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02399.22 best	Herpes_ori_bp	221.0	4.00e-65	87.6%	18.9%

D3 medium residues 435-541

PDB

D4 medium residues 630-649_843-887

PDB

Domain cluster: representative

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3q23A08	1.20.140.110	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 ›	0.55	47.0	3.63e-01	100.0%	68.8%
8bs9A01	3.90.70.10	Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases	0.52	42.0	2.84e-01	96.9%	94.7%
5jcpB01	1.10.555.10	Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein	0.50	37.0	2.66e-01	86.2%	26.2%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4942452	5050.1.1.53 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MarC	0.56	42.0	3.08e-01	84.6%	67.3%
4942122	1079.1.1.12 ↗	alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › GDT1	0.54	43.0	3.22e-01	90.8%	69.6%
5011651	1079.1.1.8 ↗	alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › LysE	0.54	42.0	3.19e-01	89.2%	66.3%

D5 medium residues 650-672_695-842

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02399.22 best	Herpes_ori_bp	135.9	2.10e-39	86.6%	17.9%

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1kf6A04	4.10.80.40	Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › succinate dehydrogenase protein domain	0.66	12.0	2.97e-01	70.8%	77.1%
2hjqA02	1.10.720.10	Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 ›	0.64	22.0	3.89e-01	76.0%	100.0%
2jnsA01	1.20.1270.220	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.56	26.0	3.68e-01	81.9%	92.6%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3252664	130.1.1.31 ↗	alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif › RNF34L-like_3rd	0.70	24.0	4.40e-01	78.9%	100.0%
4422279	6130.1.1.1 ↗	alpha complex topology › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Selenocysteine synthase N-terminal domain › Se-cys_synth_N	0.56	23.0	3.33e-01	78.9%	82.7%