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DNA_replication_origin-binding_helicase
Euk-VirGallid_alphaherpesvirus_2
DNA_replication_origin-binding_helicase__YP_001033937__Gallid_alphaherpesvirus_2__10390
Identity
- Accession:
- YP_001033937 ↗
- Protein ID:
- DNA_replication_origin-binding_helicase
- Kingdom:
- euk
Quality
72.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Mardivirus›
Gallid_alphaherpesvirus_2
TaxID: 10390
Cluster
View cluster (36 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 28-214
Domain cluster:
rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 361.6 | 1.20e-107 | 100.0% | 22.8% |
| PF00270.36 | DEAD | 32.8 | 7.80e-08 | 85.0% | 88.6% |
D2
medium
residues 219-243_270-394_478-526
Domain cluster:
rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 259.7 | 7.70e-77 | 76.4% | 20.0% |
| PF02399.22 | Herpes_ori_bp | 42.0 | 5.00e-11 | 25.6% | 6.0% |
D3
medium
residues 527-620
Domain cluster:
rep: DNA_replication_origin-binding_helicase__YP_009010995__Chimpanzee_herpesvirus_strain_105640__332937__D557-613_637-650
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 107.7 | 7.20e-31 | 100.0% | 11.3% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1w2qA01 | 1.10.110.10 | Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins | 0.62 | 40.0 | 3.76e-01 | 87.2% | 54.0% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.58 | 37.0 | 3.90e-01 | 85.1% | 72.3% |
| 1vr9A01 | 3.90.1280.20 | Alpha Beta › Alpha-Beta Complex › CBS domain Like › | 0.57 | 30.0 | 3.53e-01 | 90.4% | 73.4% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.57 | 41.0 | 3.94e-01 | 76.6% | 90.8% |
| 1vwxg01 | 6.20.370.70 | Special › Other non-globular › Rhinovirus 14, subunit 4 › | 0.55 | 22.0 | 3.46e-01 | 97.9% | 97.3% |
| 3snxA00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 44.0 | 2.86e-01 | 88.3% | 84.6% |
| 1o2dA01 | 3.40.50.1970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 43.0 | 3.59e-01 | 90.4% | 91.3% |
| 7uzsX02 | 3.90.260.10 | Alpha Beta › Alpha-Beta Complex › Coagulation Factor XIII; Chain A, domain 2 › Transglutaminase-like | 0.52 | 43.0 | 3.09e-01 | 91.5% | 32.4% |
| 7plsA01 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.52 | 41.0 | 2.84e-01 | 86.2% | 30.8% |
| 3qsgA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.51 | 43.0 | 4.06e-01 | 91.5% | 86.1% |
| 4k7cA01 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.51 | 38.0 | 2.52e-01 | 79.8% | 42.1% |
| 4ezbA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.50 | 41.0 | 3.92e-01 | 92.6% | 88.9% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3605664 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.63 | 47.0 | 3.21e-01 | 78.7% | 94.9% |
| 4927916 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.59 | 25.0 | 2.97e-01 | 83.0% | 54.0% |
| 4002132 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.58 | 40.0 | 2.80e-01 | 71.3% | 29.5% |
| 3714115 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.58 | 42.0 | 2.87e-01 | 77.7% | 84.1% |
| 3719593 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 45.0 | 2.86e-01 | 87.2% | 37.6% |
| 3321517 | 2007.2.3.9 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › PTPlike_phytase | 0.54 | 47.0 | 3.12e-01 | 97.9% | 63.6% |
| 3587631 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.53 | 46.0 | 4.11e-01 | 100.0% | 84.3% |
| 3282565 | 7579.1.1.118 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9, FrsA-like | 0.52 | 44.0 | 2.95e-01 | 97.9% | 65.6% |
| 3216070 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.51 | 44.0 | 3.09e-01 | 97.9% | 58.5% |
| 4087557 | 7581.1.1.1 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Thiolase_N | 0.51 | 39.0 | 2.76e-01 | 81.9% | 81.7% |
D4
medium
residues 621-737_788-801
D5
medium
residues 738-787
Domain cluster:
rep: DNA_replication_origin-binding_helicase_UL9__YP_009230139__Leporid_alphaherpesvirus_4__481315__D730-784
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 68.1 | 6.70e-19 | 100.0% | 6.1% |