←Back to structures

DNA_replication_origin-binding_helicase

Euk-Vir

Human_alphaherpesvirus_2

DNA_replication_origin-binding_helicase__YP_009137160__Human_alphaherpesvirus_2__10310

Identity

Accession:
YP_009137160 ↗
Protein ID:
DNA_replication_origin-binding_helicase
Kingdom:
euk

Quality

76.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Human_alphaherpesvirus_2

TaxID: 10310

Cluster

View cluster (36 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 264-285_303-428_497-554
PDB
Domain cluster: rep: CP025712.1__AUO37541.1__YDC107_5424__00064__D413-546_602-643
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF02399.22 best Herpes_ori_bp 249.5 9.60e-74 72.8% 20.1%
PF02399.22 Herpes_ori_bp 59.7 2.30e-16 28.6% 6.8%
D2 medium residues 61-133_222-261
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF02399.22 best Herpes_ori_bp 116.1 2.00e-33 66.4% 9.0%
PF02399.22 Herpes_ori_bp 56.3 2.40e-15 35.4% 4.9%
CATH (74)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3i5xA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.78 65.0 4.99e-01 88.5% 98.8%
1z6aA01 3.40.50.10810 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain 0.76 58.0 4.73e-01 80.5% 99.5%
7nadx01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.75 56.0 4.52e-01 78.8% 93.3%
3berA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 61.0 4.82e-01 86.7% 100.0%
4a15A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 58.0 4.83e-01 81.4% 98.4%
6l5oA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 55.0 4.51e-01 77.9% 92.6%
2pl3A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 57.0 4.47e-01 81.4% 79.7%
2ykgA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.73 57.0 4.54e-01 81.4% 94.9%
1wp9A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.73 57.0 4.66e-01 81.4% 92.5%
8tbxA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.73 56.0 4.42e-01 80.5% 86.2%
1qhxA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.73 50.0 4.26e-01 70.8% 68.0%
5supC01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.73 57.0 4.54e-01 81.4% 90.1%
3h1tA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.72 55.0 4.73e-01 79.6% 88.8%
1m8pA03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.72 51.0 4.27e-01 72.6% 61.4%
6s8oB02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 55.0 4.43e-01 81.4% 93.9%
8ebtA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 55.0 4.64e-01 81.4% 100.0%
2v1xA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 57.0 4.53e-01 86.7% 100.0%
6yhrA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 52.0 4.36e-01 78.8% 91.8%
5tshA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 54.0 4.01e-01 81.4% 75.4%
2ekdA00 3.40.50.11570 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Protein of unknown function DUF257 0.67 49.0 4.02e-01 76.1% 87.6%
3t15A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.67 51.0 4.58e-01 80.5% 92.9%
2rhmC00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 46.0 3.90e-01 71.7% 58.4%
3nbxX01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 51.0 4.16e-01 81.4% 70.3%
7tjhE01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 49.0 4.23e-01 78.8% 100.0%
2kbeA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 49.0 3.94e-01 80.5% 82.3%
5gvrA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 57.0 4.49e-01 96.5% 99.6%
1darA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.64 53.0 4.09e-01 90.3% 88.8%
3dnfB01 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.64 45.0 4.78e-01 90.3% 83.0%
4dqlA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.64 47.0 4.22e-01 77.9% 87.6%
6k6wC01 3.40.50.10710 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Metallo-hydrolase/oxidoreductase 0.63 47.0 4.36e-01 80.5% 84.6%
3c97A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.62 32.0 4.14e-01 72.6% 93.1%
1c4oA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 50.0 4.55e-01 88.5% 71.9%
3q41B02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 45.0 3.97e-01 80.5% 75.0%
7a8rA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.60 49.0 4.13e-01 90.3% 68.8%
4ry8C02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 45.0 4.06e-01 81.4% 83.7%
3u4qB03 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 50.0 4.10e-01 93.8% 80.7%
4yv7A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.59 44.0 4.05e-01 80.5% 86.0%
6yhrA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 48.0 3.99e-01 90.3% 65.2%
2eyqA04 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 50.0 3.85e-01 92.0% 55.0%
3dnfA03 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.58 45.0 4.77e-01 82.3% 100.0%
4m88A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 45.0 4.17e-01 83.2% 91.6%
2hqbA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 43.0 3.97e-01 79.6% 78.9%
6jimB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 46.0 4.29e-01 87.6% 72.0%
1a1vA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 48.0 4.56e-01 93.8% 92.6%
4bucA03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.56 48.0 4.61e-01 92.9% 84.4%
4kfuA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 46.0 3.81e-01 89.4% 66.3%
3nwrA02 3.20.20.110 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Ribulose bisphosphate carboxylase, large subunit, C-terminal domain 0.56 43.0 3.26e-01 83.2% 76.2%
1cnzA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.56 47.0 3.34e-01 93.8% 38.3%
2w2kA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 42.0 3.56e-01 80.5% 98.5%
1w78A02 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.56 49.0 4.70e-01 96.5% 89.4%
3e82B01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 45.0 4.22e-01 90.3% 86.3%
2g6tA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 39.0 4.20e-01 74.3% 96.9%
2oejA02 3.20.20.110 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Ribulose bisphosphate carboxylase, large subunit, C-terminal domain 0.55 43.0 3.24e-01 84.1% 74.0%
1nj1A02 3.40.50.800 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain 0.55 38.0 3.98e-01 90.3% 77.9%
6xm1C01 3.40.50.2060 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sec1/Munc18 (SM) protein, domain 1 0.55 42.0 4.03e-01 81.4% 95.4%
4qrnB00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.55 43.0 3.16e-01 87.6% 96.0%
4pg4A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 45.0 4.10e-01 92.9% 87.5%
3ke8A01 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.54 44.0 4.41e-01 88.5% 99.1%
3ngxA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 43.0 4.20e-01 85.8% 100.0%
4b4uB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 4.18e-01 87.6% 97.0%
3zl8A03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.54 47.0 4.40e-01 96.5% 84.2%
3hn7A03 3.90.190.20 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Mur ligase, C-terminal domain 0.54 45.0 4.20e-01 92.9% 87.1%
1g8kA03 3.40.228.10 Alpha Beta › 3-Layer(aba) Sandwich › Dimethylsulfoxide Reductase; domain 2 › Dimethylsulfoxide Reductase, domain 2 0.54 47.0 3.73e-01 100.0% 89.9%
2nteA02 3.40.50.10190 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › BRCT domain 0.53 34.0 3.51e-01 74.3% 69.2%
2jfzA02 3.40.50.1860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 39.0 3.85e-01 77.0% 100.0%
4qgsA01 3.40.50.1970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 44.0 3.89e-01 92.9% 96.4%
2i7gB00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.53 43.0 3.15e-01 91.2% 94.5%
1aa1B02 3.20.20.110 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Ribulose bisphosphate carboxylase, large subunit, C-terminal domain 0.53 41.0 3.06e-01 84.1% 74.0%
3cm0A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 43.0 3.68e-01 90.3% 93.5%
3kgyA00 3.40.430.10 Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A 0.52 43.0 3.50e-01 90.3% 82.6%
3s4tA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.51 42.0 3.16e-01 93.8% 87.3%
1id1A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 40.0 3.68e-01 85.0% 85.6%
4k9qA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.51 45.0 3.81e-01 100.0% 91.7%
2xdqA03 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.51 36.0 3.53e-01 74.3% 66.9%
ECOD (74)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5049581 2004.1.1.144 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD_2 0.81 64.0 4.59e-01 82.3% 96.6%
3928922 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.80 64.0 4.92e-01 83.2% 100.0%
3263629 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.77 61.0 4.45e-01 82.3% 98.6%
3714023 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.76 69.0 5.01e-01 98.2% 95.3%
None — 0.76 58.0 4.45e-01 80.5% 59.6%
None — 0.75 67.0 4.50e-01 96.5% 51.9%
3323007 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.73 58.0 4.13e-01 82.3% 78.3%
3263816 2004.1.1.120 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII 0.73 56.0 4.22e-01 81.4% 70.6%
1381895 2004.1.1.120 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ResIII 0.73 56.0 4.78e-01 81.4% 87.7%
3739853 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.73 58.0 4.53e-01 85.0% 97.0%
3612550 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.72 61.0 4.71e-01 91.2% 92.2%
3471628 2004.1.1.162 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad51 0.72 54.0 4.04e-01 77.9% 88.8%
3787057 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.72 55.0 4.73e-01 79.6% 92.9%
3677330 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.71 53.0 4.61e-01 77.9% 91.8%
4175288 2004.1.1.364 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C 0.71 64.0 4.06e-01 98.2% 44.8%
3938064 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.71 55.0 4.43e-01 80.5% 88.8%
3356641 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.71 58.0 4.35e-01 87.6% 91.5%
3936409 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.71 55.0 4.22e-01 81.4% 74.2%
3961952 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.71 54.0 5.03e-01 80.5% 87.1%
None — 0.70 57.0 4.12e-01 86.7% 79.0%
3308399 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 54.0 4.64e-01 82.3% 96.1%
None — 0.70 53.0 3.59e-01 80.5% 37.1%
3936890 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.70 58.0 4.35e-01 89.4% 84.1%
3334202 2004.1.1.135 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PIF1 0.69 55.0 5.00e-01 82.3% 90.3%
4366164 2004.1.1.42 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.69 53.0 3.57e-01 81.4% 36.2%
3650238 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.68 53.0 4.95e-01 80.5% 95.6%
3779694 2004.1.1.356 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SLFN_GTPase-like 0.68 52.0 3.36e-01 80.5% 31.9%
3742124 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.66 59.0 4.23e-01 96.5% 75.6%
5059167 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.66 51.0 4.35e-01 82.3% 62.7%
3716079 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 57.0 3.84e-01 96.5% 50.6%
5069471 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.65 50.0 4.79e-01 81.4% 86.9%
3703529 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 53.0 4.07e-01 91.2% 73.3%
5042627 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 48.0 4.65e-01 80.5% 88.5%
4044261 2004.1.1.161 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › TmcA_N 0.63 49.0 4.26e-01 84.1% 96.1%
3649691 2004.1.1.299 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF1995 0.62 49.0 3.81e-01 84.1% 73.2%
3310100 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 48.0 4.47e-01 81.4% 84.3%
3466240 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.62 46.0 3.97e-01 80.5% 68.9%
5037782 2003.1.10.23 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain › LysX_preATP_grasp 0.61 35.0 4.01e-01 76.1% 75.3%
5000670 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.61 50.0 4.52e-01 87.6% 86.0%
3213844 2004.1.1.194 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C_2 0.61 50.0 3.74e-01 90.3% 48.8%
4037986 7558.1.1.1 ↗ a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Acyltransferase 0.60 46.0 3.81e-01 80.5% 62.5%
3980676 2004.1.1.203 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD_C_2 0.60 54.0 4.29e-01 100.0% 80.4%
4027001 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.60 50.0 3.92e-01 93.8% 68.6%
4886125 1137.1.1.1 ↗ a+b two layers › Tetrapyrrole methylase C-terminal domain-like › Tetrapyrrole methylase C-terminal domain › Tetrapyrrole methylase C-terminal domain › TP_methylase 0.59 41.0 4.16e-01 71.7% 100.0%
3726775 7570.1.1.0 ↗ a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain 0.59 51.0 4.29e-01 93.8% 84.3%
3320235 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.59 41.0 4.50e-01 80.5% 91.1%
4981671 7570.1.1.5 ↗ a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › PF31156 0.58 50.0 4.85e-01 93.8% 91.2%
3429343 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.58 44.0 3.90e-01 79.6% 98.2%
3713295 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 50.0 4.02e-01 95.6% 62.6%
3177077 2003.1.1.37 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 2-Hacid_dh_C 0.57 45.0 3.66e-01 82.3% 100.0%
4888756 148.1.3.13 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_9 0.57 41.0 3.50e-01 75.2% 79.1%
3601092 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.57 30.0 3.78e-01 71.7% 87.7%
3271108 7568.1.1.4 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain › BRCT_2 0.56 39.0 3.94e-01 90.3% 72.7%
9758 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 48.0 4.37e-01 96.5% 94.2%
4316198 7570.1.1.1 ↗ a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C 0.56 47.0 4.44e-01 92.9% 80.6%
4074155 2003.1.8.12 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › MurCD/PglD N-terminal domain-like › CoA_binding_3 0.55 41.0 4.11e-01 79.6% 75.0%
2574425 2003.2.1.1 ↗ a/b three-layered sandwiches › Rossmann-like › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Molybdopterin 0.55 47.0 3.73e-01 98.2% 98.0%
3645849 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.54 41.0 3.50e-01 80.5% 58.5%
3218935 7585.1.1.1 ↗ a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 0.54 41.0 3.98e-01 81.4% 96.2%
4959285 2003.1.5.62 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I 0.54 42.0 3.03e-01 82.3% 55.7%
3731197 2007.2.3.8 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase3 0.54 42.0 3.19e-01 85.0% 78.3%
1106391 7570.1.1.1 ↗ a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C 0.54 47.0 4.41e-01 96.5% 85.4%
5050757 2003.1.10.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.53 36.0 4.13e-01 70.8% 100.0%
3261231 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.52 40.0 3.37e-01 80.5% 72.3%
3839203 7570.1.1.0 ↗ a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain 0.52 45.0 4.48e-01 96.5% 97.5%
2602038 7510.1.1.0 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like 0.52 40.0 3.96e-01 85.0% 76.4%
4089253 7588.1.1.1 ↗ a/b three-layered sandwiches › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase › LYTB 0.52 37.0 4.00e-01 74.3% 96.7%
3276245 323.1.1.3 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding 0.52 42.0 3.18e-01 88.5% 44.4%
3795398 7570.1.1.0 ↗ a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain 0.52 39.0 3.55e-01 84.1% 99.4%
3813073 2004.1.1.73 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.51 43.0 3.66e-01 92.0% 90.5%
4315439 2007.1.5.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like 0.51 44.0 3.36e-01 96.5% 81.4%
3175921 7558.1.1.0 ↗ a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase 0.51 38.0 2.88e-01 77.9% 40.7%
4887153 2002.1.1.1 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › RuBisCO_large 0.50 38.0 2.85e-01 80.5% 74.6%
3285700 2002.1.1.16 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Bac_luciferase 0.50 40.0 2.93e-01 85.8% 93.2%
D3 medium residues 134-221
PDB
Domain cluster: rep: DNA_replication_origin-binding_helicase__YP_009352913__Columbid_alphaherpesvirus_1__93386__D112-191
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02399.22 best Herpes_ori_bp 159.2 1.90e-46 100.0% 10.7%
D4 medium residues 431-496
PDB
D5 medium residues 579-654_831-871
PDB
Domain cluster: rep: DNA_replication_origin-binding_helicase__YP_010084982__Beluga_whale_alphaherpesvirus_1__1434720__D546-648
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02399.22 best Herpes_ori_bp 72.7 2.60e-20 65.8% 9.2%
D6 medium residues 655-768
PDB
Domain cluster: rep: DNA_replication_origin-binding_helicase__YP_010087593__Cervid_alphaherpesvirus_3__2115790__D666-744
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02399.22 best Herpes_ori_bp 114.4 6.50e-33 100.0% 14.3%
D7 medium residues 769-830
PDB
Domain cluster: rep: DNA_replication_origin-binding_helicase_UL9__YP_009230139__Leporid_alphaherpesvirus_4__481315__D730-784
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02399.22 best Herpes_ori_bp 81.6 5.50e-23 100.0% 7.6%