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DNA_replication_origin-binding_helicase
Euk-VirCervid_alphaherpesvirus_3
DNA_replication_origin-binding_helicase__YP_010087593__Cervid_alphaherpesvirus_3__2115790
Identity
- Accession:
- YP_010087593 ↗
- Protein ID:
- DNA_replication_origin-binding_helicase
- Kingdom:
- euk
Quality
85.4
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Varicellovirus›
Cervid_alphaherpesvirus_3
TaxID: 2115790
Cluster
View cluster (36 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 49-238
Domain cluster:
rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 302.5 | 8.80e-90 | 100.0% | 23.1% |
| PF00270.36 | DEAD | 26.8 | 5.40e-06 | 83.7% | 90.4% |
D2
high
residues 243-408_475-528
Domain cluster:
rep: CP025712.1__AUO37541.1__YDC107_5424__00064__D413-546_602-643
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 228.6 | 2.00e-67 | 75.9% | 20.4% |
| PF02399.22 | Herpes_ori_bp | 34.7 | 8.00e-09 | 25.4% | 6.5% |
D3
medium
residues 409-474
Domain cluster:
rep: DNA_replication_origin-binding_helicase__NP_040173__Human_alphaherpesvirus_3__10335__D393-453
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 86.1 | 2.40e-24 | 100.0% | 7.9% |
D4
medium
residues 532-665
Domain cluster:
rep: DNA_replication_origin-binding_helicase__YP_010084982__Beluga_whale_alphaherpesvirus_1__1434720__D546-648
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 79.9 | 1.80e-22 | 97.8% | 13.8% |
D5
medium
residues 666-744
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 34.8 | 7.70e-09 | 100.0% | 9.4% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2dznF00 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.64 | 36.0 | 3.87e-01 | 84.8% | 63.8% |
| 2kj8A00 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.61 | 31.0 | 2.73e-01 | 70.9% | 32.2% |
| 2yqzA02 | 1.10.8.900 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.59 | 32.0 | 3.41e-01 | 70.9% | 60.3% |
| 1wy9A00 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.57 | 43.0 | 3.88e-01 | 82.3% | 86.5% |
| 3au5A03 | 1.20.80.10 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › | 0.56 | 49.0 | 4.38e-01 | 98.7% | 98.2% |
| 3vw4A01 | 1.10.340.50 | Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › | 0.55 | 34.0 | 3.26e-01 | 72.2% | 53.3% |
| 2oo2A00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.54 | 42.0 | 4.33e-01 | 89.9% | 86.8% |
| 3cnlA02 | 1.10.1580.10 | Mainly Alpha › Orthogonal Bundle › Conserved Hypothetical Protein Ylqf; Chain: A; domain 2 › | 0.53 | 42.0 | 4.09e-01 | 92.4% | 78.0% |
| 1v5kA00 | 1.10.418.10 | Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain | 0.51 | 44.0 | 3.93e-01 | 100.0% | 95.7% |
| 3bkhA02 | 1.10.530.10 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.51 | 38.0 | 3.03e-01 | 83.5% | 50.0% |
| 2grjA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 41.0 | 3.26e-01 | 92.4% | 96.1% |
| 1qamA02 | 1.10.8.100 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › rRNA adenine dimethylase, C-terminal domain | 0.50 | 36.0 | 3.62e-01 | 94.9% | 76.9% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4997475 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.55 | 44.0 | 2.99e-01 | 86.1% | 96.1% |
| 5008138 | 169.1.1.1 ↗ | alpha complex topology › Aldehyde ferredoxin oxidoreductase-C › Aldehyde ferredoxin oxidoreductase-C › Aldehyde ferredoxin oxidoreductase-C › AFOR_C | 0.52 | 41.0 | 2.65e-01 | 86.1% | 20.0% |
| 3737699 | 2004.1.1.272 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › RNA12 | 0.51 | 42.0 | 3.00e-01 | 88.6% | 30.9% |
| 5027497 | 632.6.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit | 0.51 | 42.0 | 4.28e-01 | 91.1% | 91.3% |