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DNA_replication_origin-binding_helicase
Euk-VirHuman_betaherpesvirus_7
DNA_replication_origin-binding_helicase__YP_073813__Human_betaherpesvirus_7__10372
Identity
- Accession:
- YP_073813 ↗
- Protein ID:
- DNA_replication_origin-binding_helicase
- Kingdom:
- euk
Quality
79.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Roseolovirus›
Human_betaherpesvirus_7
TaxID: 10372
Cluster
View cluster (7 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 21-199
Domain cluster:
rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 221.2 | 3.40e-65 | 99.4% | 21.8% |
D2
high
residues 204-349_411-454
Domain cluster:
rep: CP025712.1__AUO37541.1__YDC107_5424__00064__D413-546_602-643
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 182.3 | 2.00e-53 | 77.9% | 15.5% |
| PF02399.22 | Herpes_ori_bp | 27.5 | 1.20e-06 | 25.3% | 5.1% |
D3
high
residues 588-699_749-760
Domain cluster:
rep: DNA_replication_origin-binding_helicase__YP_009344918__Murine_roseolovirus__1940555__D581-690
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 69.3 | 2.80e-19 | 96.8% | 13.8% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3zihA00 | 3.30.110.150 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › SepF-like protein | 0.61 | 31.0 | 3.78e-01 | 89.5% | 74.7% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.55 | 44.0 | 4.32e-01 | 84.7% | 91.9% |
| 3cuqA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 32.0 | 3.73e-01 | 91.9% | 87.7% |
| 4cxfA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.53 | 29.0 | 3.38e-01 | 91.1% | 73.6% |
| 7xc2A02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 37.0 | 3.91e-01 | 100.0% | 82.1% |
| 1ka8A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 35.0 | 3.82e-01 | 91.9% | 82.0% |
| 1a7eA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.52 | 37.0 | 3.86e-01 | 97.6% | 78.0% |
| 2v1nA01 | 1.10.10.2030 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DNA/RNA-binding protein Kin17, conserved domain | 0.51 | 34.0 | 3.69e-01 | 98.4% | 82.2% |
| 3rrkA02 | 1.20.1460.20 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › | 0.51 | 27.0 | 2.57e-01 | 84.7% | 39.4% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.50 | 39.0 | 4.01e-01 | 96.0% | 85.7% |
| 3tl4X02 | 1.10.10.2420 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.50 | 26.0 | 3.25e-01 | 99.2% | 83.3% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3212250 | 135.1.1.0 ↗ | alpha arrays › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain › Transducin (alpha subunit), insertion domain | 0.59 | 35.0 | 3.67e-01 | 71.8% | 63.6% |
| 54604 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.52 | 38.0 | 3.87e-01 | 97.6% | 78.0% |
| 4264297 | 101.1.2.760 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF30824 | 0.51 | 34.0 | 3.35e-01 | 95.2% | 63.0% |
| 3603690 | 601.37.1.8 ↗ | alpha bundles › Four-helical up-and-down bundle › Photosystem II lipoprotein Psb27 › Photosystem II lipoprotein Psb27 › PF27232 | 0.50 | 44.0 | 4.09e-01 | 100.0% | 83.6% |
| 5017517 | 5054.1.1.198 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › PF27232 | 0.50 | 44.0 | 3.84e-01 | 100.0% | 70.0% |
| 3243556 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.50 | 34.0 | 2.97e-01 | 91.1% | 42.4% |
| 4092855 | 140.1.1.11 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 | 0.50 | 33.0 | 3.14e-01 | 94.4% | 54.7% |
D4
medium
residues 350-410