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DNA_replication_protein
Euk-VirCricetid_gammaherpesvirus_2
DNA_replication_protein__YP_004207892__Cricetid_gammaherpesvirus_2__1605972
Identity
- Accession:
- YP_004207892 ↗
- Protein ID:
- DNA_replication_protein
- Kingdom:
- euk
Quality
89.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Cricetid_gammaherpesvirus_2
TaxID: 1605972
Cluster
View cluster (58 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 486-674
Domain cluster:
rep: primase__YP_009345453__Noumeavirus__1955558__D12-194
D2
high
residues 698-824
Domain cluster:
rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03121.21 best | Herpes_UL52 | 64.3 | 1.00e-17 | 59.1% | 97.3% |
D3
medium
residues 1-152
D4
medium
residues 153-226
D5
medium
residues 227-285
Domain cluster:
rep: E70__YP_007016467__Murid_betaherpesvirus_8__1261657__D218-274
D6
medium
residues 340-427
Domain cluster:
rep: ORF56__YP_001129409__Human_gammaherpesvirus_8__37296__D349-421
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1dq3A04 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.71 | 39.0 | 3.58e-01 | 93.2% | 41.2% |
| 2lrrA00 | 3.30.1370.50 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain | 0.70 | 37.0 | 4.11e-01 | 89.8% | 64.3% |
| 1b24A01 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.64 | 41.0 | 4.01e-01 | 93.2% | 60.0% |
| 3pxpA02 | 3.30.450.180 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.60 | 50.0 | 3.86e-01 | 90.9% | 77.4% |
| 5axgA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.59 | 34.0 | 3.06e-01 | 92.0% | 40.5% |
| 4e1oA03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.58 | 40.0 | 3.91e-01 | 71.6% | 89.8% |
| 4hh2B03 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.56 | 47.0 | 4.52e-01 | 90.9% | 96.0% |
| 3wnkA04 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.55 | 32.0 | 2.85e-01 | 94.3% | 39.2% |
| 1d06A00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.55 | 46.0 | 4.07e-01 | 92.0% | 80.8% |
| 1r62A00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.55 | 38.0 | 3.30e-01 | 71.6% | 96.3% |
| 1s67L00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.54 | 45.0 | 4.11e-01 | 92.0% | 87.4% |
| 2qsrA01 | 3.90.1150.50 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Transcription-repair-coupling factor, D7 domain | 0.54 | 37.0 | 3.16e-01 | 71.6% | 90.3% |
| 2anrA02 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.54 | 33.0 | 3.50e-01 | 94.3% | 70.7% |
| 4r3aA02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.53 | 36.0 | 3.03e-01 | 93.2% | 43.0% |
| 4za1C00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 33.0 | 3.26e-01 | 94.3% | 58.7% |
| 6dw1A00 | 2.70.170.10 | Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain | 0.53 | 40.0 | 2.99e-01 | 93.2% | 33.3% |
| 3hunA01 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.52 | 37.0 | 2.62e-01 | 73.9% | 48.6% |
| 2q14A02 | 1.20.1250.30 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 39.0 | 3.18e-01 | 98.9% | 42.8% |
| 2wdoA00 | 3.90.470.20 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain | 0.52 | 42.0 | 3.88e-01 | 94.3% | 96.7% |
| 2y8yA01 | 3.30.70.1200 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 1 | 0.51 | 35.0 | 3.57e-01 | 93.2% | 72.1% |
| 1vs3A02 | 3.30.70.660 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Pseudouridine synthase I, catalytic domain, C-terminal subdomain | 0.51 | 43.0 | 3.69e-01 | 94.3% | 58.3% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4993483 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.70 | 38.0 | 3.64e-01 | 93.2% | 44.8% |
| 4113237 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.70 | 39.0 | 3.79e-01 | 93.2% | 49.5% |
| 4931923 | 304.5.1.7 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF2179 | 0.69 | 36.0 | 3.79e-01 | 93.2% | 53.8% |
| 3972097 | 304.14.1.0 ↗ | a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) | 0.69 | 36.0 | 3.92e-01 | 94.3% | 60.0% |
| 3552466 | 320.1.1.1 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H | 0.67 | 35.0 | 3.93e-01 | 89.8% | 64.3% |
| 4993850 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.64 | 37.0 | 3.61e-01 | 94.3% | 51.6% |
| 3386674 | 304.14.1.1 ↗ | a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR | 0.62 | 35.0 | 3.82e-01 | 97.7% | 66.7% |
| 3407270 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.60 | 36.0 | 3.88e-01 | 94.3% | 69.3% |
| 3357806 | 320.1.1.1 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain › R3H | 0.59 | 32.0 | 3.61e-01 | 90.9% | 67.7% |
| 4981204 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 42.0 | 4.24e-01 | 92.0% | 74.2% |
| 5046055 | 223.1.1.13 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_3 | 0.57 | 47.0 | 4.29e-01 | 92.0% | 87.5% |
| 5007983 | 223.1.1.2 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › PAS | 0.57 | 48.0 | 4.31e-01 | 92.0% | 83.3% |
| 5010582 | 310.3.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related | 0.57 | 34.0 | 3.27e-01 | 93.2% | 51.0% |
| 4989318 | 328.8.1.1 ↗ | a+b two layers › IF3-like › Schlafen 8 › Schlafen 8 › SLFN_AlbA_2 | 0.55 | 38.0 | 3.42e-01 | 95.5% | 49.2% |
| 5006311 | 223.1.1.2 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › PAS | 0.55 | 45.0 | 4.07e-01 | 92.0% | 80.0% |
| 4989528 | 223.1.1.25 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_9 | 0.54 | 45.0 | 4.11e-01 | 92.0% | 76.5% |
| 5004330 | 328.8.1.1 ↗ | a+b two layers › IF3-like › Schlafen 8 › Schlafen 8 › SLFN_AlbA_2 | 0.53 | 36.0 | 3.29e-01 | 94.3% | 50.8% |
| 4937824 | 328.8.1.1 ↗ | a+b two layers › IF3-like › Schlafen 8 › Schlafen 8 › SLFN_AlbA_2 | 0.53 | 40.0 | 3.45e-01 | 95.5% | 50.3% |
| 4168395 | 3019.1.1.1 ↗ | beta sandwiches › gp11/flagellar cap protein FliD insertion domain › gp11/flagellar cap protein FliD insertion domain › gp11/flagellar cap protein FliD insertion domain › Flagellin_IN | 0.52 | 43.0 | 3.94e-01 | 93.2% | 71.7% |
| 3875198 | 11.1.1.108 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › C2-set_2 | 0.52 | 29.0 | 2.76e-01 | 94.3% | 41.8% |
| 4279545 | 306.9.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › MecA substrate binding domain › MecA substrate binding domain › MecA | 0.51 | 39.0 | 4.04e-01 | 92.0% | 91.3% |
| 3716228 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.51 | 38.0 | 3.29e-01 | 78.4% | 71.4% |
| 3165390 | 304.24.1.36 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › SPOR | 0.51 | 37.0 | 3.86e-01 | 98.9% | 83.7% |
| 3283806 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.51 | 36.0 | 3.14e-01 | 73.9% | 89.3% |
| 3460420 | 304.51.1.0 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related | 0.50 | 37.0 | 3.55e-01 | 78.4% | 91.4% |
D7
medium
residues 436-485
Domain cluster:
rep: ORF56__YP_001129409__Human_gammaherpesvirus_8__37296__D437-488