←Back to structures

DNA_topoisomerase_1b

Euk-Vir

Acanthamoeba_polyphaga_mimivirus

DNA_topoisomerase_1b__YP_003986690__Acanthamoeba_polyphaga_mimivirus__212035

Identity

Accession:
YP_003986690 ↗
Protein ID:
DNA_topoisomerase_1b
Kingdom:
euk

Quality

83.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Imitervirales› Mimiviridae› Mimivirus› Acanthamoeba_polyphaga_mimivirus

TaxID: 212035

Cluster

View cluster (42 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 12-77
PDB
Domain cluster: rep: hypothetical_protein_OLNG_00081__YP_007674723__Ostreococcus_lucimarinus_virus_OlV5__754064__D2-65
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF21338.3 best Top1B_N_bact 61.4 7.60e-17 74.2% 98.0%
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2f4qA01 3.30.66.10 Alpha Beta › 2-Layer Sandwich › Viral Topoisomerase I › DNA topoisomerase I domain 0.84 60.0 5.80e-01 100.0% 68.1%
2a5hA03 6.20.120.40 Special › Other non-globular › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.69 32.0 3.30e-01 89.4% 43.5%
1vccA00 3.30.66.10 Alpha Beta › 2-Layer Sandwich › Viral Topoisomerase I › DNA topoisomerase I domain 0.66 59.0 5.63e-01 100.0% 88.3%
5ajiB02 2.30.30.60 Mainly Beta › Roll › SH3 type barrels. › 0.63 36.0 4.02e-01 98.5% 74.0%
1yr1A00 3.40.50.10960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.62 54.0 4.49e-01 100.0% 73.9%
2mysA01 2.30.30.360 Mainly Beta › Roll › SH3 type barrels. › Myosin S1 fragment, N-terminal 0.57 35.0 3.94e-01 97.0% 85.4%
5ighA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.56 39.0 3.54e-01 97.0% 53.4%
3h27A00 3.50.50.100 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › 0.56 46.0 2.90e-01 98.5% 96.3%
4fgmA02 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.56 46.0 3.18e-01 100.0% 52.4%
3lh4A00 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 40.0 3.39e-01 77.3% 74.8%
3ab1A02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 47.0 3.89e-01 98.5% 92.9%
2x5rA01 3.30.470.40 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › 0.55 44.0 3.81e-01 95.5% 82.6%
2ra2B00 2.30.30.100 Mainly Beta › Roll › SH3 type barrels. › 0.55 34.0 3.58e-01 87.9% 70.7%
2z0uA00 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.52 38.0 3.15e-01 78.8% 77.3%
6l4lA02 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.52 47.0 3.70e-01 100.0% 72.1%
3ocrA00 3.40.225.10 Alpha Beta › 3-Layer(aba) Sandwich › L-fuculose-1-phosphate Aldolase › Class II aldolase/adducin N-terminal domain 0.52 41.0 2.93e-01 93.9% 85.3%
8c0zE01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 43.0 3.49e-01 95.5% 93.9%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1176176 818.1.1.2 ↗ a+b two layers › DNA topoisomerase I domain › DNA topoisomerase I domain › DNA topoisomerase I domain › Top1B_N_bact 0.84 60.0 6.01e-01 100.0% 74.2%
3973165 818.1.1.0 ↗ a+b two layers › DNA topoisomerase I domain › DNA topoisomerase I domain › DNA topoisomerase I domain 0.76 69.0 6.43e-01 100.0% 81.2%
4939485 2003.6.1.5 ↗ a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › Phos_pyr_kin 0.61 44.0 2.98e-01 77.3% 30.6%
3723441 7502.1.1.7 ↗ a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › HGTP_anticodon2 0.60 47.0 3.99e-01 90.9% 71.7%
3508414 2.6.1.0 ↗ beta barrels › OB-fold › Staphylococcal nuclease › Staphylococcal nuclease 0.59 41.0 3.70e-01 74.2% 74.7%
3697874 5.1.4.16 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CPSF_A 0.57 49.0 3.10e-01 100.0% 32.2%
3713678 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.57 49.0 3.14e-01 100.0% 47.1%
4121491 7502.1.1.1 ↗ a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › HGTP_anticodon 0.55 44.0 3.86e-01 92.4% 80.0%
3606628 5.1.5.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.55 46.0 2.97e-01 100.0% 29.0%
4009644 2008.1.1.160 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PF27151 0.53 46.0 3.45e-01 100.0% 46.2%
4562258 314.1.1.12 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › LplA-B_cat 0.53 48.0 3.24e-01 100.0% 69.8%
5011586 5104.1.1.1 ↗ a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 0.53 48.0 3.83e-01 100.0% 60.0%
3449236 7579.1.1.5 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S10 0.52 44.0 2.91e-01 100.0% 64.4%
5058747 56.2.1.1 ↗ beta sandwiches › Epsilon subunit of F1F0-ATP synthase-N › CO dehydrogenase accessory protein CooT › CO dehydrogenase accessory protein CooT › CooT 0.52 31.0 3.30e-01 84.8% 67.2%
3718563 243.6.1.0 ↗ a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain 0.51 39.0 4.07e-01 100.0% 93.3%
4315251 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.51 38.0 3.68e-01 80.3% 81.3%
3798360 214.1.1.0 ↗ a+b two layers › SH2 › SH2 › SH2 0.51 37.0 3.20e-01 89.4% 49.5%
3263649 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.50 33.0 2.75e-01 81.8% 33.8%
5064206 2008.1.1.59 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.50 42.0 2.79e-01 92.4% 24.2%
D2 high residues 110-231
PDB
Domain cluster: rep: S16_GE16_scaffold_10741_prodigal-single.1__X__X__00162__D901-1023
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01028.26 best Topoisom_I 56.3 4.40e-15 95.9% 46.1%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3m4aA03 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.91 82.0 8.41e-01 97.5% 97.5%
2h7fX02 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.86 76.0 5.89e-01 100.0% 46.9%
1a31A03 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.81 75.0 6.91e-01 99.2% 78.7%
1a41A01 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.79 65.0 6.40e-01 100.0% 81.9%
5jk0B01 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.70 59.0 5.27e-01 100.0% 63.6%
1ci3M02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.63 30.0 4.17e-01 79.5% 93.1%
2xcmC00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.57 32.0 3.60e-01 91.8% 69.6%
3j7aF03 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.55 28.0 3.51e-01 82.0% 80.3%
3g5kA00 3.90.45.10 Alpha Beta › Alpha-Beta Complex › Peptide Deformylase › Peptide deformylase 0.51 36.0 3.17e-01 73.8% 85.2%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3973159 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.93 87.0 8.00e-01 100.0% 78.7%
177048 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.90 84.0 7.70e-01 100.0% 79.3%
3282325 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.89 85.0 7.67e-01 100.0% 78.1%
138326 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.85 75.0 7.17e-01 100.0% 81.3%
3599060 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.85 76.0 6.23e-01 100.0% 56.5%
3886079 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.81 75.0 6.16e-01 100.0% 58.0%
4357768 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.80 64.0 6.28e-01 100.0% 78.5%
5044666 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.79 75.0 6.77e-01 100.0% 81.9%
4413773 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.79 64.0 6.14e-01 100.0% 75.6%
3621756 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.79 66.0 6.23e-01 100.0% 75.7%
4210863 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.78 64.0 6.24e-01 100.0% 79.2%
5052502 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.70 61.0 5.90e-01 100.0% 83.7%
3839627 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.69 61.0 5.88e-01 100.0% 85.2%
3838435 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.68 46.0 5.10e-01 77.0% 87.4%
4373021 2.4.1.6 ↗ beta barrels › OB-fold › MOP-like › MOP-like › CysA_C_terminal 0.66 29.0 3.26e-01 77.0% 50.5%
3383138 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.66 35.0 4.31e-01 73.8% 80.8%
3839222 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.65 57.0 5.47e-01 100.0% 83.6%
4594302 2.4.1.2 ↗ beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2 0.64 31.0 3.24e-01 77.9% 47.8%
5010537 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.62 33.0 4.03e-01 91.0% 78.5%
4443040 2.4.1.1 ↗ beta barrels › OB-fold › MOP-like › MOP-like › TOBE 0.62 31.0 3.33e-01 77.9% 52.9%
4391061 2.4.1.2 ↗ beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2 0.62 30.0 3.06e-01 76.2% 46.7%
3969569 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.61 29.0 3.99e-01 77.0% 90.0%
4432262 319.1.1.3 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.61 34.0 3.49e-01 93.4% 55.0%
4236900 2.4.1.2 ↗ beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2 0.60 31.0 3.11e-01 81.1% 45.7%
5077813 2.4.1.0 ↗ beta barrels › OB-fold › MOP-like › MOP-like 0.60 31.0 3.05e-01 81.1% 43.7%
3892091 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 34.0 2.92e-01 93.4% 34.7%
3255946 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 36.0 4.26e-01 77.9% 92.5%
3789900 220.1.1.5 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PID 0.58 38.0 3.67e-01 81.1% 58.5%
4966092 2.4.1.2 ↗ beta barrels › OB-fold › MOP-like › MOP-like › TOBE_2 0.57 28.0 2.84e-01 73.8% 44.4%
3737837 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.55 27.0 3.69e-01 75.4% 89.2%
3919870 220.1.1.22 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C 0.55 40.0 4.12e-01 77.0% 97.5%
1877618 330.15.1.1 ↗ a+b two layers › dsRBD-like › VtrA protein periplasmic domain › VtrA protein periplasmic domain › VtrA_C 0.54 27.0 3.09e-01 80.3% 63.3%
3582308 220.1.1.16 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF1681 0.53 37.0 4.12e-01 76.2% 92.6%
3497290 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.52 39.0 4.06e-01 78.7% 96.5%
5030451 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.51 30.0 3.22e-01 93.4% 65.7%
4028996 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.51 37.0 3.56e-01 75.4% 75.9%
D3 high residues 237-334
PDB
Domain cluster: rep: DNA_topoisomerase_type_I__YP_005296281__Cotia_virus_SPAn232__930275__D223-313
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.79 69.0 7.03e-01 96.9% 97.9%
2f4qA02 1.10.132.120 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.78 70.0 6.40e-01 96.9% 81.1%
1s7zA01 1.20.120.780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DNA mimic ocr 0.69 50.0 4.95e-01 75.5% 98.0%
1zk8B02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.67 47.0 4.22e-01 72.4% 54.5%
1l3pA00 1.20.120.320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen 0.66 53.0 5.32e-01 88.8% 93.1%
1fc3B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 47.0 4.66e-01 78.6% 82.2%
2hvrA03 1.10.10.1810 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › RNA ligase 0.61 44.0 4.64e-01 76.5% 93.1%
2cfoA05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.60 48.0 4.79e-01 88.8% 84.6%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.60 44.0 4.32e-01 78.6% 73.1%
1ux8A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 41.0 3.88e-01 72.4% 99.2%
3onqA03 1.10.10.2840 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PucR C-terminal helix-turn-helix domain 0.57 38.0 3.51e-01 82.7% 50.4%
1j09A05 1.10.10.350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.57 45.0 4.51e-01 85.7% 85.7%
3cx5A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.57 39.0 3.05e-01 71.4% 74.4%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 39.0 3.87e-01 73.5% 90.2%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 37.0 3.87e-01 70.4% 89.2%
3eeeA00 3.90.1520.10 Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain 0.54 39.0 3.14e-01 94.9% 38.8%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 37.0 3.81e-01 72.4% 83.5%
3k1hA00 3.30.1120.180 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 0.53 43.0 4.15e-01 90.8% 88.7%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.52 36.0 3.65e-01 72.4% 90.7%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 40.0 3.37e-01 84.7% 53.8%
1bucA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.51 40.0 3.79e-01 87.8% 75.6%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.50 40.0 3.74e-01 89.8% 90.1%
2xq9A02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.50 43.0 4.04e-01 95.9% 100.0%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
161395 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.81 73.0 7.43e-01 100.0% 97.9%
3289668 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.79 69.0 6.93e-01 93.9% 100.0%
5027329 186.1.1.0 ↗ alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N 0.75 51.0 5.74e-01 70.4% 93.3%
4283614 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.66 47.0 4.63e-01 75.5% 69.5%
4970690 3930.1.1.0 ↗ alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase 0.65 43.0 3.82e-01 72.4% 48.1%
4121585 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.65 46.0 4.91e-01 76.5% 85.9%
4960043 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.63 49.0 3.96e-01 83.7% 96.4%
4182308 101.8.1.2 ↗ alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 0.63 50.0 3.88e-01 86.7% 39.5%
5028782 5073.1.2.0 ↗ alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.62 49.0 3.92e-01 85.7% 47.8%
3739805 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.60 45.0 3.59e-01 81.6% 98.1%
3804806 192.29.1.34 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF677 0.58 48.0 4.42e-01 89.8% 80.0%
3633107 5057.1.1.0 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.57 47.0 4.75e-01 89.8% 96.8%
3396665 101.1.1.112 ↗ alpha arrays › HTH › HTH › Three-helical HTH › MADF_DNA_bdg 0.57 49.0 5.00e-01 94.9% 94.7%
3456942 5048.1.1.1 ↗ alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP 0.56 43.0 3.70e-01 100.0% 52.7%
3601585 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.56 34.0 2.92e-01 87.8% 35.8%
4609538 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 46.0 4.39e-01 92.9% 77.4%
5075088 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 41.0 3.26e-01 80.6% 77.6%
5011995 601.3.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain 0.54 43.0 4.32e-01 90.8% 87.0%
5073302 3930.1.1.3 ↗ alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical 0.53 37.0 3.33e-01 72.4% 51.4%
3887051 101.1.1.112 ↗ alpha arrays › HTH › HTH › Three-helical HTH › MADF_DNA_bdg 0.52 43.0 4.53e-01 89.8% 98.9%
4026469 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 43.0 3.24e-01 88.8% 50.6%