←Back to structures

DNA_topoisomerase_2

Euk-Vir

Acanthamoeba_polyphaga_moumouvirus

DNA_topoisomerase_2__YP_007354303__Acanthamoeba_polyphaga_moumouvirus__1269028

Identity

Accession:: YP_007354303 ↗
Protein ID:: DNA_topoisomerase_2
Kingdom:: euk

Quality

83.0 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Imitervirales› Mimiviridae› Moumouvirus› Acanthamoeba_polyphaga_moumouvirus

TaxID: 1269028

Cluster

View cluster (39 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 66-252

PDB

Domain cluster: rep: IMGVR_UViG_3300039190_000305-3300039190-Ga0399989_003201_3_1937__D82-97_167-336

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02518.32 best	HATPase_c	40.3	5.50e-10	76.5%	90.1%

D2 high residues 275-407

PDB

Domain cluster: rep: DNA_gyrase_subunit_B__YP_009352802__Kaumoebavirus_Viruses.__X__D311-415

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00204.32 best	DNA_gyraseB	78.2	7.50e-22	99.2%	75.9%

D3 high residues 1098-1202

PDB

Domain cluster: rep: DNA_topoisomerase_2__YP_003986988__Acanthamoeba_polyphaga_mimivirus__212035__D1115-1212

D4 medium residues 21-65_253-274

PDB

Domain cluster: representative

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3242297	810.1.1.1 ↗	a+b two layers › BtrG-like (Pfam 03674) › BtrG-like (Pfam 03674) › BtrG-like (Pfam 03674) › ChaC	0.50	34.0	2.55e-01	70.1%	84.3%

D5 medium residues 414-557_598-630_661-727

PDB

Domain cluster: rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D385-517_553-621_640-664

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01751.29 best	Toprim	34.5	2.50e-08	47.1%	84.4%
PF16898.11	TOPRIM_C	84.5	9.90e-24	44.7%	68.0%

D6 medium residues 560-597

PDB

Domain cluster: representative

CATH (13)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3aqoA01	3.30.70.3400	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.64	51.0	4.21e-01	100.0%	96.2%
1qysA00	3.30.1710.10	Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein	0.63	52.0	4.05e-01	100.0%	54.3%
2qv7A02	2.60.200.40	Mainly Beta › Sandwich › Tumour Suppressor Smad4 ›	0.62	44.0	3.00e-01	78.9%	33.6%
2bghA01	3.30.559.10	Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain	0.61	43.0	2.68e-01	73.7%	82.6%
1c1kA02	1.10.220.50	Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Bacteriophage T4, Gp59, helicase assembly protein, C-terminal domain	0.59	44.0	3.40e-01	97.4%	44.3%
3mpoA02	3.30.1240.10	Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 ›	0.57	43.0	3.30e-01	86.8%	91.6%
2wadA02	3.90.1310.10	Alpha Beta › Alpha-Beta Complex › Penicillin-binding protein 2a (Domain 2) › Penicillin-binding protein 2a (Domain 2)	0.56	46.0	3.20e-01	100.0%	26.4%
1pzxA02	2.20.28.50	Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › DegV, N-terminal domain, peripheral subdomain	0.55	41.0	4.21e-01	100.0%	94.3%
3jr7A02	2.20.28.50	Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › DegV, N-terminal domain, peripheral subdomain	0.55	43.0	4.38e-01	97.4%	92.1%
3fdjA02	2.20.28.50	Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › DegV, N-terminal domain, peripheral subdomain	0.54	41.0	4.11e-01	100.0%	89.5%
6cngA02	2.20.28.50	Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › DegV, N-terminal domain, peripheral subdomain	0.53	40.0	4.01e-01	100.0%	92.1%
3ic3A01	3.30.2370.10	Alpha Beta › 2-Layer Sandwich › putative pyruvate dehydrogenase fold › putative pyruvate dehydrogenase	0.51	40.0	3.44e-01	89.5%	93.8%
2q8kA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.51	40.0	3.62e-01	100.0%	98.3%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3520955	2006.1.3.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DNA_gyraseB_C,Toprim	0.78	66.0	3.91e-01	100.0%	13.6%
3784671	220.1.1.0 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like	0.68	48.0	3.21e-01	78.9%	23.2%
3603400	304.120.1.6 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer	0.59	44.0	3.78e-01	92.1%	100.0%
4928834	210.1.3.0 ↗	a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases	0.54	39.0	2.56e-01	92.1%	55.5%

D7 medium residues 728-846

PDB

Domain cluster: rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D669-796

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00521.27 best	DNA_topoisoIV	140.1	1.40e-40	100.0%	26.2%

D8 medium residues 847-923_1062-1097

PDB

Domain cluster: rep: DNA_topoisomerase_II__YP_009325819__Only_Syngen_Nebraska_virus_5__1917232__D775-833_920-935

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00521.27 best	DNA_topoisoIV	81.6	7.70e-23	69.9%	18.6%