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DNA_topoisomerase_2

Euk-Vir

Salmon_gill_poxvirus

DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908

Identity

Accession:
YP_009162467 ↗
Protein ID:
DNA_topoisomerase_2
Kingdom:
euk

Quality

58.2 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Salmonpoxvirus› Salmon_gill_poxvirus

TaxID: 1680908

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 385-517_553-621_640-664
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01751.29 best Toprim 37.9 2.30e-09 49.3% 97.9%
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4kxwA03 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.66 39.0 5.02e-01 88.5% 98.5%
5exeA02 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.66 41.0 5.01e-01 92.5% 95.1%
3nbmA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.65 32.0 4.52e-01 83.7% 100.0%
1pdoA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.64 34.0 4.40e-01 83.3% 89.9%
3iprA00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.62 35.0 4.41e-01 83.3% 89.8%
3mtqB00 3.40.50.510 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component 0.61 34.0 4.32e-01 85.0% 89.1%
4rk6A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 33.0 4.37e-01 83.7% 96.0%
3k9cB01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 34.0 4.40e-01 85.0% 96.2%
4o5aA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.58 33.0 4.20e-01 84.6% 95.5%
3grfA01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.58 28.0 3.48e-01 84.6% 72.5%
4f2gA01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.58 30.0 3.65e-01 83.7% 74.8%
1k68A00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 35.0 4.35e-01 83.7% 97.9%
3kznA01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.56 33.0 3.83e-01 83.7% 78.9%
5b7hB01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.56 24.0 3.43e-01 83.3% 81.5%
4myrC00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.56 32.0 4.16e-01 82.8% 100.0%
4p0tB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 36.0 4.33e-01 84.1% 100.0%
1puiA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 38.0 4.38e-01 89.9% 96.4%
3fbtA01 3.40.50.10860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 0.54 30.0 3.69e-01 82.8% 85.0%
3v38A00 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.54 46.0 4.06e-01 89.9% 89.5%
4bjhB01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.54 29.0 3.48e-01 82.8% 77.6%
4kvfA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.52 34.0 4.00e-01 85.9% 92.5%
5ilnA01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.52 30.0 3.28e-01 83.3% 64.8%
4am8E01 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.52 30.0 3.46e-01 83.3% 75.4%
1xs5A01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.52 26.0 3.24e-01 84.6% 76.9%
5tdeA03 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.51 41.0 4.43e-01 95.2% 98.4%
4gmgA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 39.0 4.07e-01 94.7% 87.2%
1yoeA00 3.90.245.10 Alpha Beta › Alpha-Beta Complex › Inosine-uridine Nucleoside N-ribohydrolase; Chain A › Ribonucleoside hydrolase-like 0.51 42.0 3.83e-01 87.2% 93.7%
2n0sA01 3.40.50.1780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.50 30.0 3.43e-01 89.0% 77.0%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3964707 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.87 68.0 6.81e-01 80.2% 100.0%
4878011 2006.1.3.21 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOPRIM_C 0.86 67.0 6.94e-01 78.9% 100.0%
4124102 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.86 69.0 6.78e-01 81.9% 99.2%
3164150 2006.1.3.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DNA_gyraseB_C,Toprim 0.85 66.0 6.68e-01 78.9% 100.0%
3594652 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.84 81.0 7.52e-01 100.0% 98.9%
3789608 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.83 80.0 7.44e-01 99.6% 98.2%
3551383 2006.1.3.3 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim,TOPRIM_C 0.83 80.0 7.28e-01 100.0% 96.9%
3213306 2006.1.3.21 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOPRIM_C 0.83 76.0 7.12e-01 95.2% 100.0%
3520955 2006.1.3.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DNA_gyraseB_C,Toprim 0.80 77.0 7.26e-01 100.0% 97.7%
5018445 7522.1.1.0 ↗ a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.70 39.0 4.91e-01 88.5% 88.6%
3957015 7522.1.1.4 ↗ a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PFOR_II 0.68 39.0 4.83e-01 93.4% 88.1%
5041312 7522.1.1.4 ↗ a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PFOR_II 0.68 38.0 4.98e-01 93.4% 98.4%
3589377 2010.1.1.3 ↗ a/b three-layered sandwiches › EDD domain › EDD domain › EDD domain › EIIA-man 0.67 35.0 4.61e-01 84.6% 88.5%
4397030 2007.1.5.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › Asp_Glu_race 0.65 34.0 4.36e-01 82.4% 84.4%
3193526 7579.1.1.0 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.64 45.0 4.05e-01 70.9% 100.0%
3960446 7522.1.1.0 ↗ a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.64 39.0 4.79e-01 87.7% 95.8%
5009436 2007.1.5.2 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like › CCG 0.63 31.0 4.34e-01 82.4% 98.1%
4935863 2007.1.5.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › ATC-like 0.61 32.0 4.32e-01 85.9% 94.2%
3789041 2006.1.3.11 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOP6A-Spo11_Toprim 0.61 38.0 4.39e-01 90.7% 83.6%
3960088 4126.1.1.5 ↗ a/b three-layered sandwiches › beta-carbonic anhydrase-like › beta-carbonic anhydrase › beta-carbonic anhydrase › Pro_CA_2 0.60 38.0 4.70e-01 86.8% 98.6%
3278503 7522.1.1.5 ↗ a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › Transketolase_C_1 0.60 39.0 4.75e-01 90.7% 98.7%
1123475 2007.1.3.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.58 33.0 4.24e-01 82.8% 98.4%
4360353 2003.1.1.120 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD-bd_HRPKS_sdrA 0.54 38.0 4.09e-01 88.1% 84.2%
2858023 2004.1.1.177 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › CENP-M 0.53 37.0 4.20e-01 86.8% 92.6%
4008873 4303.1.1.1 ↗ alpha arrays › lvD/EDD N-terminal domain-like › lvD/EDD N-terminal domain-like › lvD/EDD N-terminal domain-like › ILVD_EDD 0.51 47.0 3.84e-01 99.6% 91.9%
3345250 7512.1.1.32 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_4 0.51 42.0 4.11e-01 85.5% 84.9%
4016967 129.1.1.54 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD-bd_HRPKS_sdrA 0.51 37.0 3.99e-01 85.5% 87.2%
3188708 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.51 39.0 4.06e-01 87.7% 87.3%
D2 high residues 669-796
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 63.1 3.20e-17 100.0% 29.5%
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bjtA05 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.93 89.0 6.89e-01 100.0% 51.8%
2xcqA02 3.90.199.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5 0.86 82.0 6.23e-01 100.0% 47.2%
1p6rA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 45.0 5.49e-01 97.7% 92.7%
2co5A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 48.0 5.57e-01 82.8% 94.6%
3gw2A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 45.0 5.12e-01 82.8% 87.1%
5nl9A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 43.0 5.29e-01 70.3% 94.0%
3eyyA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 42.0 5.08e-01 72.7% 93.9%
1fnnB03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.68 50.0 5.55e-01 95.3% 95.1%
2fnaA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 39.0 4.86e-01 80.5% 100.0%
4f52C02 3.30.230.130 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › Cullin; Chain C, Domain 2 0.66 48.0 4.42e-01 100.0% 59.7%
7xc2A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 50.0 5.40e-01 91.4% 95.3%
2v1nA01 1.10.10.2030 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DNA/RNA-binding protein Kin17, conserved domain 0.64 45.0 5.01e-01 88.3% 91.1%
1vtnC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 45.0 4.94e-01 94.5% 92.2%
6pcoC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 51.0 5.08e-01 91.4% 83.3%
3zq7A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 40.0 4.50e-01 74.2% 83.2%
2a07J00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.62 38.0 4.52e-01 95.3% 95.2%
2mbfA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 40.0 4.46e-01 73.4% 87.6%
3zmdA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 50.0 4.76e-01 91.4% 75.7%
3ke2B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.60 42.0 4.65e-01 96.1% 94.8%
3e1sA01 1.10.10.2220 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.59 41.0 4.69e-01 71.9% 100.0%
4a1nA02 6.10.250.1250 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.58 25.0 3.62e-01 73.4% 96.0%
3zcoA00 1.10.10.2450 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.57 51.0 5.15e-01 95.3% 96.1%
1nklA00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.55 31.0 3.73e-01 78.9% 87.2%
1n97A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.55 37.0 2.72e-01 70.3% 72.5%
2fokB01 3.90.241.10 Alpha Beta › Alpha-Beta Complex › FokI Restriction Endonuclease; Chain A, domain 1 › Foki Restriction Endonuclease, Chain A, domain 1 0.52 46.0 3.53e-01 95.3% 46.3%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3096548 101.1.2.9 ↗ alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.95 92.0 9.07e-01 100.0% 100.0%
3594651 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.94 91.0 9.09e-01 100.0% 99.2%
4238706 101.1.2.9 ↗ alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.94 91.0 6.58e-01 100.0% 92.5%
3768919 4016.1.1.1 ↗ alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV 0.93 90.0 6.54e-01 100.0% 94.7%
1165372 101.1.2.9 ↗ alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.93 76.0 7.43e-01 84.4% 79.0%
4969077 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.87 81.0 7.59e-01 96.9% 82.7%
2754385 101.1.2.9 ↗ alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.87 83.0 7.60e-01 100.0% 80.6%
4370976 101.1.2.9 ↗ alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.86 79.0 7.36e-01 96.9% 79.4%
4865162 101.1.2.9 ↗ alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV 0.86 67.0 6.71e-01 84.4% 79.4%
4631918 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.81 45.0 5.80e-01 72.7% 94.7%
4985370 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.80 46.0 5.39e-01 72.7% 81.1%
5078617 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.79 52.0 5.94e-01 87.5% 89.5%
5030817 101.1.2.54 ↗ alpha arrays › HTH › HTH › winged helix domain › Penicillinase_R 0.79 46.0 4.62e-01 72.7% 56.9%
3272289 101.1.2.53 ↗ alpha arrays › HTH › HTH › winged helix domain › Mnd1 0.78 45.0 4.35e-01 74.2% 52.1%
4997662 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.78 50.0 5.35e-01 93.8% 74.5%
4965088 101.1.2.909 ↗ alpha arrays › HTH › HTH › winged helix domain › DUF5797 0.78 48.0 5.75e-01 97.7% 92.9%
4009179 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.77 47.0 5.51e-01 76.6% 86.7%
5000830 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.77 49.0 5.69e-01 89.1% 90.0%
5073138 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.76 51.0 5.41e-01 98.4% 76.5%
4927652 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.75 48.0 5.84e-01 99.2% 98.8%
5000571 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.74 44.0 5.40e-01 74.2% 93.8%
4958024 101.1.2.101 ↗ alpha arrays › HTH › HTH › winged helix domain › Cdc6_C 0.74 50.0 5.69e-01 96.1% 91.6%
5023957 101.1.2.280 ↗ alpha arrays › HTH › HTH › winged helix domain › HTH_12 0.74 46.0 5.67e-01 93.8% 100.0%
3661546 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.74 53.0 5.43e-01 85.9% 76.0%
5075222 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.74 42.0 5.20e-01 94.5% 90.0%
3499387 101.1.2.154 ↗ alpha arrays › HTH › HTH › winged helix domain › CDT1_C 0.72 46.0 4.91e-01 96.1% 73.6%
2685 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.72 48.0 5.64e-01 82.8% 97.8%
5046890 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.72 49.0 4.77e-01 78.1% 63.6%
5035979 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.72 56.0 5.80e-01 93.0% 86.7%
3242025 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.72 47.0 5.59e-01 78.1% 98.8%
3459794 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.71 51.0 5.71e-01 93.0% 95.0%
3552400 101.1.2.566 ↗ alpha arrays › HTH › HTH › winged helix domain › CDT1, CDT1_C 0.71 48.0 3.61e-01 96.1% 30.3%
3464139 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.71 52.0 5.52e-01 85.9% 85.2%
3519118 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.71 40.0 4.90e-01 89.8% 92.0%
3841412 101.1.2.154 ↗ alpha arrays › HTH › HTH › winged helix domain › CDT1_C 0.71 48.0 5.06e-01 96.1% 76.5%
5055033 101.1.2.913 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_Lhr 0.71 46.0 5.32e-01 93.0% 93.3%
5032533 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.70 44.0 5.18e-01 93.0% 92.9%
3297063 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.70 51.0 5.71e-01 93.0% 96.0%
3587554 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.70 48.0 5.33e-01 82.0% 89.0%
5046131 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.70 51.0 5.63e-01 87.5% 96.0%
3420624 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.70 49.0 5.35e-01 82.8% 87.6%
3373659 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.69 49.0 5.36e-01 96.1% 88.6%
5030693 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.69 48.0 5.30e-01 82.0% 87.6%
3467284 101.1.2.154 ↗ alpha arrays › HTH › HTH › winged helix domain › CDT1_C 0.69 47.0 5.05e-01 96.1% 81.5%
3414623 101.1.2.566 ↗ alpha arrays › HTH › HTH › winged helix domain › CDT1, CDT1_C 0.69 47.0 3.54e-01 96.1% 30.2%
3225058 101.1.2.566 ↗ alpha arrays › HTH › HTH › winged helix domain › CDT1, CDT1_C 0.69 47.0 3.44e-01 96.9% 27.4%
4977854 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.69 43.0 5.08e-01 96.1% 92.9%
4971686 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.69 48.0 5.21e-01 81.2% 86.7%
3383404 101.1.2.154 ↗ alpha arrays › HTH › HTH › winged helix domain › CDT1_C 0.69 48.0 5.34e-01 100.0% 89.4%
3744259 101.1.2.154 ↗ alpha arrays › HTH › HTH › winged helix domain › CDT1_C 0.69 49.0 4.87e-01 96.9% 71.5%
5067342 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.68 45.0 5.15e-01 93.0% 93.3%
4979487 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.68 50.0 4.87e-01 86.7% 69.3%
3613894 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.67 51.0 3.95e-01 100.0% 37.7%
4973555 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.67 49.0 4.44e-01 87.5% 56.5%
5035276 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.67 44.0 5.16e-01 98.4% 95.6%
5077022 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.67 46.0 5.10e-01 81.2% 90.0%
3290800 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.66 39.0 4.57e-01 75.0% 83.3%
3561932 101.1.2.137 ↗ alpha arrays › HTH › HTH › winged helix domain › OST-HTH 0.66 40.0 4.80e-01 73.4% 91.8%
3739861 101.1.2.198 ↗ alpha arrays › HTH › HTH › winged helix domain › ORC1_wHTH 0.64 52.0 5.44e-01 94.5% 94.8%
4013474 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.64 45.0 4.84e-01 72.7% 99.1%
4525548 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.64 46.0 5.09e-01 91.4% 95.0%
3503111 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.64 41.0 4.46e-01 77.3% 78.1%
5070358 101.1.2.913 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_Lhr 0.63 49.0 4.72e-01 94.5% 71.7%
3821352 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.63 50.0 5.09e-01 84.4% 85.6%
3426019 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.63 53.0 5.06e-01 93.0% 78.6%
3435414 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.63 50.0 5.26e-01 84.4% 93.9%
3282607 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.62 49.0 4.95e-01 91.4% 83.2%
3827266 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.62 54.0 5.20e-01 93.0% 89.0%
3440580 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.62 49.0 4.88e-01 92.2% 79.3%
3439642 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.62 54.0 5.23e-01 93.0% 88.6%
3824526 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.62 52.0 5.14e-01 92.2% 85.2%
3428027 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.61 51.0 5.08e-01 92.2% 83.7%
3322387 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.61 53.0 4.87e-01 92.2% 91.3%
3315625 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.60 52.0 4.86e-01 93.0% 77.4%
3280645 101.1.2.8 ↗ alpha arrays › HTH › HTH › winged helix domain › Trans_reg_C 0.58 41.0 4.63e-01 76.6% 96.8%
4964643 101.1.2.913 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_Lhr 0.58 50.0 4.71e-01 95.3% 77.4%
5000260 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.57 51.0 4.67e-01 99.2% 75.6%
3463151 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.56 45.0 4.39e-01 91.4% 77.2%
4944051 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.56 49.0 4.48e-01 96.1% 81.8%
3187002 101.1.2.635 ↗ alpha arrays › HTH › HTH › winged helix domain › CDT1_C, PF26121 0.55 45.0 3.42e-01 100.0% 37.5%
3323843 101.1.2.386 ↗ alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.53 45.0 4.11e-01 92.2% 85.9%
D3 medium residues 1-68_194-236
PDB
Domain cluster: rep: GyrB-like_ATPase_domain_protein__YP_784277__Nile_crocodilepox_virus__1285600__D7-67_190-221
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1mhxA00 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.59 28.0 3.61e-01 74.8% 76.9%
1l1lA01 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.57 47.0 3.11e-01 91.0% 79.1%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3317524 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.75 50.0 3.95e-01 96.4% 34.9%
3799597 192.15.1.0 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.64 26.0 3.03e-01 72.1% 50.6%
4072997 263.1.1.7 ↗ a+b three layers › SRF-like › SRF-like › SRF-like › Nrf1_DNA-bind 0.55 28.0 3.30e-01 82.9% 69.2%
4141047 593.1.1.0 ↗ alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like 0.54 32.0 2.37e-01 73.9% 25.0%
3634448 6166.1.1.1 ↗ alpha bundles › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › ERG4_ERG24 0.54 37.0 2.99e-01 70.3% 88.6%
3275078 6166.1.1.1 ↗ alpha bundles › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › ERG4_ERG24 0.53 37.0 2.99e-01 70.3% 87.7%
D4 medium residues 69-193
PDB
Domain cluster: rep: GyrB-like_ATPase_domain_protein__YP_784274__Nile_crocodilepox_virus__1285600__D74-178
D5 medium residues 237-305
PDB
D6 medium residues 797-887
PDB
D7 medium residues 1085-1148
PDB