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DNA_topoisomerase_II

Euk-Vir

Marseillevirus_marseillevirus

DNA_topoisomerase_II__YP_003406916__Marseillevirus_marseillevirus__694581

Identity

Accession:
YP_003406916 ↗
Protein ID:
DNA_topoisomerase_II
Kingdom:
euk

Quality

86.5 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Marseilleviridae› Marseillevirus› Marseillevirus_marseillevirus

TaxID: 694581

Cluster

View cluster (39 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 253-403
PDB
Domain cluster: rep: topoisomerase_IIA__YP_009001040__Pithovirus_sibericum__1450746__D250-321_335-390
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00204.32 best DNA_gyraseB 35.5 1.00e-08 72.9% 48.9%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qzrA02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.84 67.0 7.35e-01 90.7% 100.0%
3lnuA02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.78 74.0 7.22e-01 100.0% 99.4%
4hy1A02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.76 70.0 6.97e-01 98.7% 98.1%
3zkbI02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.75 71.0 6.94e-01 100.0% 98.1%
3cwvA02 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.70 63.0 6.34e-01 97.4% 99.3%
1z5bB03 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.64 56.0 5.64e-01 93.4% 94.6%
3d2lA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.53 20.0 3.12e-01 88.1% 84.1%
1y8cA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.53 19.0 3.06e-01 89.4% 83.3%
6ezmA01 3.30.230.40 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › Imidazole glycerol phosphate dehydratase; domain 1 0.51 35.0 4.01e-01 87.4% 97.2%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3220683 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.85 82.0 7.90e-01 100.0% 95.2%
3513708 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.83 79.0 7.77e-01 100.0% 97.5%
4000834 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.83 79.0 7.65e-01 100.0% 94.5%
3275256 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.82 78.0 7.49e-01 100.0% 96.5%
3585145 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.82 78.0 7.62e-01 99.3% 96.9%
4641709 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.82 77.0 7.25e-01 100.0% 93.9%
3799215 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.82 77.0 7.51e-01 100.0% 94.5%
3433616 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.81 76.0 7.50e-01 98.7% 95.6%
3594648 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.80 75.0 7.41e-01 99.3% 94.4%
4234522 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.80 76.0 7.26e-01 100.0% 97.1%
3970715 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.80 75.0 7.15e-01 100.0% 93.7%
4040519 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.80 74.0 7.21e-01 98.7% 91.5%
4261801 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.79 75.0 6.87e-01 100.0% 87.9%
4288775 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.79 74.0 6.94e-01 99.3% 92.8%
3807571 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.79 74.0 7.03e-01 100.0% 93.1%
4207771 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.78 74.0 6.99e-01 100.0% 93.7%
3964340 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.78 73.0 6.81e-01 100.0% 92.4%
4027043 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.78 73.0 6.95e-01 100.0% 94.9%
3967155 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.78 73.0 6.94e-01 100.0% 93.7%
4380841 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.78 73.0 6.94e-01 100.0% 93.1%
4298571 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.78 73.0 6.78e-01 100.0% 92.4%
4945732 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.77 73.0 6.90e-01 100.0% 94.3%
4339883 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.76 71.0 6.59e-01 99.3% 94.6%
1388837 212.1.1.2 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_gyraseB 0.74 67.0 6.89e-01 96.0% 99.3%
3973573 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.66 52.0 5.71e-01 85.4% 99.2%
4158298 212.1.1.9 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_mis_repair 0.66 51.0 5.50e-01 86.1% 93.8%
4062719 212.1.1.9 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_mis_repair 0.65 50.0 5.47e-01 85.4% 97.6%
4026555 212.1.1.9 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_mis_repair 0.65 50.0 5.50e-01 85.4% 98.4%
4028943 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.64 56.0 4.98e-01 94.7% 73.6%
4940508 212.1.1.24 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 0.64 49.0 5.38e-01 94.0% 100.0%
4963188 212.1.1.9 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_mis_repair 0.63 50.0 5.38e-01 83.4% 96.9%
3734627 212.1.1.9 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_mis_repair 0.61 48.0 5.10e-01 84.8% 98.5%
5000360 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.60 38.0 4.60e-01 80.8% 96.0%
4319033 212.1.1.9 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_mis_repair 0.59 49.0 5.01e-01 87.4% 100.0%
4885780 212.1.1.8 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribonuclease_P 0.55 39.0 4.36e-01 86.8% 92.4%
3262031 212.1.1.10 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › RNase_PH 0.50 39.0 4.17e-01 92.7% 98.4%
D2 high residues 417-539_607-665
PDB
Domain cluster: rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D385-517_553-621_640-664
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01751.29 best Toprim 35.8 1.00e-08 61.0% 88.5%
D3 high residues 670-805_829-839
PDB
Domain cluster: rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D669-796
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00521.27 best DNA_topoisoIV 139.2 2.70e-40 95.9% 30.9%
D4 high residues 970-1088
PDB
Domain cluster: rep: putative_DNA_topoisomerase__YP_294202__Emiliania_huxleyi_virus_86__181082__D963-1088
D5 medium residues 17-79_214-249
PDB
Domain cluster: rep: conserved_DNA_topoisomerase_II__YP_009094655__Melbournevirus__1560514__D21-79_215-249
D6 medium residues 80-213
PDB
Domain cluster: rep: GyrB-like_ATPase_domain_protein__YP_784274__Nile_crocodilepox_virus__1285600__D74-178
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1pvgA01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.96 86.0 6.76e-01 100.0% 50.4%
1s14B00 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.90 64.0 5.69e-01 100.0% 54.5%
2o1uB01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.81 55.0 5.06e-01 100.0% 55.8%
1b63A01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.78 65.0 5.46e-01 100.0% 54.2%
1y4uB01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.78 57.0 4.92e-01 100.0% 51.5%
3cwvA01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.77 61.0 5.27e-01 100.0% 56.1%
1h7sA01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.73 56.0 4.89e-01 100.0% 54.9%
1mu5A01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.73 64.0 5.38e-01 98.5% 58.6%
1nijA02 3.30.1220.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Yjia; Chain: A;domain 2 › CobW-like, C-terminal domain 0.66 45.0 4.79e-01 96.3% 80.2%
7k0xA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 29.0 3.63e-01 100.0% 78.2%
2b39A10 2.60.120.1540 Mainly Beta › Sandwich › Jelly Rolls › 0.53 33.0 3.52e-01 96.3% 71.6%
2a5hA03 6.20.120.40 Special › Other non-globular › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.52 17.0 2.36e-01 100.0% 48.4%
3ua0A00 6.20.280.10 Special › Other non-globular › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.52 26.0 3.23e-01 87.3% 77.2%
2g30A02 3.30.310.10 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein 0.51 31.0 3.33e-01 95.5% 68.1%
6btdA00 3.40.225.10 Alpha Beta › 3-Layer(aba) Sandwich › L-fuculose-1-phosphate Aldolase › Class II aldolase/adducin N-terminal domain 0.51 36.0 3.17e-01 81.3% 48.8%
ECOD (50)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3789605 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.96 86.0 6.77e-01 100.0% 50.6%
3998214 225.1.1.3 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.95 84.0 6.52e-01 100.0% 47.8%
3594649 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.95 83.0 6.54e-01 100.0% 49.4%
4617838 225.1.1.3 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.94 83.0 6.50e-01 100.0% 49.4%
4875911 225.1.1.3 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.90 80.0 6.20e-01 100.0% 47.1%
1223478 225.1.1.3 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.89 74.0 5.73e-01 100.0% 44.1%
1223480 225.1.1.3 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.88 74.0 6.25e-01 100.0% 56.9%
4038381 225.1.1.3 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.88 76.0 6.21e-01 100.0% 53.3%
3959843 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.88 75.0 5.96e-01 100.0% 49.2%
4945731 225.1.1.38 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › DNA_gyraseB 0.88 76.0 6.14e-01 100.0% 52.2%
3198261 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.86 74.0 6.44e-01 89.6% 62.6%
3461648 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.84 76.0 6.02e-01 100.0% 52.1%
4107504 225.1.1.3 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c 0.82 67.0 5.57e-01 100.0% 52.6%
3317524 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.82 77.0 6.36e-01 97.8% 67.4%
3530518 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.81 69.0 5.89e-01 100.0% 59.0%
3974412 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.80 66.0 5.65e-01 100.0% 56.6%
4259064 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.80 66.0 5.62e-01 100.0% 56.6%
3789513 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.77 67.0 5.47e-01 100.0% 53.0%
4013379 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.77 64.0 5.30e-01 100.0% 52.0%
4927750 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.77 60.0 5.08e-01 100.0% 51.2%
None — 0.75 64.0 5.28e-01 100.0% 53.0%
4940507 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.74 52.0 5.20e-01 83.6% 70.4%
None — 0.74 63.0 5.35e-01 100.0% 57.1%
4029843 212.1.1.0 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.74 63.0 5.16e-01 100.0% 51.3%
4935742 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.74 61.0 5.18e-01 100.0% 56.1%
3367679 225.1.1.13 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HSP90 0.74 61.0 5.63e-01 100.0% 68.8%
3421099 225.1.1.2 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HSP90,HATPase_c_3 0.74 66.0 5.13e-01 100.0% 47.5%
3308932 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.74 65.0 5.28e-01 100.0% 52.5%
3255595 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.73 66.0 5.62e-01 98.5% 62.0%
5019992 884.1.1.0 ↗ a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain 0.73 49.0 5.24e-01 93.3% 79.1%
5002020 884.1.1.0 ↗ a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain 0.73 49.0 5.30e-01 94.0% 80.0%
3595333 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.73 64.0 5.39e-01 100.0% 58.7%
None — 0.72 64.0 5.34e-01 100.0% 57.3%
3716539 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.72 67.0 5.44e-01 100.0% 56.2%
3369389 884.1.1.1 ↗ a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › CobW_C 0.72 43.0 5.08e-01 91.8% 85.3%
5014095 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.71 25.0 3.75e-01 97.0% 71.7%
4464688 884.1.1.1 ↗ a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › CobW_C 0.71 44.0 5.13e-01 94.0% 87.2%
3461740 884.1.1.1 ↗ a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › CobW_C 0.68 43.0 4.87e-01 91.8% 83.8%
3313688 884.1.1.1 ↗ a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › CobW_C 0.68 42.0 4.78e-01 91.0% 82.0%
4076203 225.1.1.7 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.68 58.0 4.65e-01 100.0% 48.4%
4930695 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.67 62.0 4.82e-01 98.5% 66.5%
3522105 884.1.1.1 ↗ a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › CobW_C 0.66 43.0 4.81e-01 90.3% 83.8%
3377134 225.1.1.0 ↗ a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.64 48.0 4.62e-01 97.8% 68.7%
4976436 884.1.1.0 ↗ a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain 0.60 42.0 4.42e-01 94.0% 79.2%
5084091 10.1.2.183 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) › PPC 0.57 33.0 3.90e-01 91.0% 82.1%
4027527 929.1.1.0 ↗ beta duplicates or obligate multimers › Resistin › Resistin › Resistin 0.55 33.0 4.10e-01 94.0% 95.3%
3401203 59.1.3.0 ↗ beta complex topology › triple barrel › triple barrel › RNA polymerase I subunits A49/A34.5 dimerization domains 0.55 23.0 2.91e-01 100.0% 61.2%
3225599 10.32.1.218 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › DUF7154 0.54 36.0 3.06e-01 98.5% 40.9%
5055086 10.1.2.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) 0.52 32.0 3.67e-01 97.0% 85.3%
5057532 101.1.2.893 ↗ alpha arrays › HTH › HTH › winged helix domain › DUF2226 0.50 34.0 2.64e-01 91.8% 32.5%
D7 medium residues 540-606
PDB
Domain cluster: rep: DNA_topoisomerase_II__YP_009506801__Tunisvirus_fontaine2__1421067__D565-621
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF16898.11 best TOPRIM_C 48.4 1.50e-12 94.0% 45.3%
D8 medium residues 855-940
PDB
Domain cluster: rep: DNA_topoisomerase_II__YP_009173327__Chrysochromulina_ericina_virus__455364__D878-969