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E1_envelope_glycoprotein
Euk-VirVenezuelan_equine_encephalitis_virus
E1_envelope_glycoprotein__NP_741967__Venezuelan_equine_encephalitis_virus__11036
Identity
- Accession:
- NP_741967 ↗
- Protein ID:
- E1_envelope_glycoprotein
- Kingdom:
- euk
Quality
74.7
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Alsuviricetes›
Martellivirales›
Togaviridae›
Alphavirus›
Venezuelan_equine_encephalitis_virus
TaxID: 11036
Cluster
View cluster (14 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-43_120-181_271-281
Domain cluster:
rep: structural_polyprotein__YP_009058893__Middelburg_virus__11023__D819-862_948-985_1091-1106
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01589.22 best | Alpha_E1_glycop | 57.3 | 1.70e-15 | 62.6% | 12.5% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1rerA01 | 2.60.98.10 | Mainly Beta › Sandwich › Tick-borne Encephalitis virus Glycoprotein; domain 1 › Tick-borne Encephalitis virus Glycoprotein, domain 1 | 0.83 | 80.0 | 7.74e-01 | 100.0% | 92.1% |
| 1bp1A01 | 3.15.10.10 | Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › Bactericidal permeability-increasing protein; domain 1 | 0.60 | 46.0 | 4.02e-01 | 81.7% | 90.0% |
| 6gp1A00 | 3.30.1300.40 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.59 | 29.0 | 3.72e-01 | 90.4% | 81.5% |
| 7wa9A01 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.58 | 43.0 | 3.98e-01 | 75.7% | 73.8% |
| 3m9qA01 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.58 | 33.0 | 4.08e-01 | 92.2% | 90.3% |
| 3lhnA00 | 2.40.128.640 | Mainly Beta › Beta Barrel › Lipocalin › | 0.57 | 39.0 | 4.01e-01 | 95.7% | 73.8% |
| 3efmA02 | 2.40.170.20 | Mainly Beta › Beta Barrel › Maltoporin; Chain A › TonB-dependent receptor, beta-barrel domain | 0.57 | 40.0 | 2.75e-01 | 72.2% | 31.7% |
| 3exzB00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.57 | 43.0 | 3.91e-01 | 77.4% | 99.3% |
| 1d6uA03 | 2.70.98.20 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain | 0.57 | 47.0 | 3.29e-01 | 93.0% | 91.2% |
| 2gtlN02 | 2.40.128.620 | Mainly Beta › Beta Barrel › Lipocalin › | 0.56 | 49.0 | 4.30e-01 | 94.8% | 67.6% |
| 2z4hA01 | 2.40.128.300 | Mainly Beta › Beta Barrel › Lipocalin › NlpE, N-terminal domain | 0.56 | 37.0 | 4.36e-01 | 92.2% | 100.0% |
| 5ay6A01 | 2.60.98.20 | Mainly Beta › Sandwich › Tick-borne Encephalitis virus Glycoprotein; domain 1 › Flagellar hook protein FlgE | 0.55 | 50.0 | 4.39e-01 | 100.0% | 100.0% |
| 5w17A01 | 2.40.128.110 | Mainly Beta › Beta Barrel › Lipocalin › Lipid/polyisoprenoid-binding, YceI-like | 0.55 | 48.0 | 4.38e-01 | 93.9% | 94.7% |
| 1p4tA00 | 2.40.160.20 | Mainly Beta › Beta Barrel › Porin › | 0.55 | 47.0 | 4.26e-01 | 93.0% | 83.2% |
| 2gtlM02 | 2.40.128.620 | Mainly Beta › Beta Barrel › Lipocalin › | 0.55 | 49.0 | 4.27e-01 | 95.7% | 69.3% |
| 3rd6A00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.54 | 48.0 | 4.42e-01 | 96.5% | 75.0% |
| 3mnmA00 | 2.60.40.1230 | Mainly Beta › Sandwich › Immunoglobulin-like › Gamma-adaptin ear (GAE) domain | 0.54 | 33.0 | 3.37e-01 | 93.0% | 60.7% |
| 2bi0A01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.53 | 40.0 | 3.61e-01 | 79.1% | 97.4% |
| 1uunA01 | 2.60.40.1650 | Mainly Beta › Sandwich › Immunoglobulin-like › Porin MspA (Ig-like beta-sandwich domain) | 0.52 | 44.0 | 4.20e-01 | 91.3% | 87.1% |
| 4b0bB00 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.52 | 40.0 | 3.50e-01 | 80.9% | 79.9% |
| 1xteA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.52 | 39.0 | 3.97e-01 | 80.0% | 86.2% |
| 1gkuB07 | 2.60.510.20 | Mainly Beta › Sandwich › EV matrix protein fold › | 0.51 | 38.0 | 4.05e-01 | 100.0% | 87.3% |
| 3qq2B00 | 2.40.128.130 | Mainly Beta › Beta Barrel › Lipocalin › Autotransporter beta-domain | 0.51 | 45.0 | 3.55e-01 | 100.0% | 88.4% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 406733 | 5090.1.1.3 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › Alpha_E1_glycop | 0.82 | 77.0 | 5.57e-01 | 100.0% | 95.2% |
| 4840163 | 11.1.1.28 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Alpha_E1_glycop | 0.82 | 77.0 | 5.58e-01 | 100.0% | 95.6% |
| 3056811 | 5090.1.1.2 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › Hanta_Gc_N | 0.78 | 71.0 | 5.12e-01 | 100.0% | 89.9% |
| 5028250 | 5090.1.1.0 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains | 0.70 | 57.0 | 5.99e-01 | 100.0% | 93.3% |
| 3285112 | 883.1.1.0 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like | 0.64 | 48.0 | 4.10e-01 | 80.0% | 75.8% |
| 5030457 | 5090.1.1.0 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains | 0.61 | 54.0 | 5.50e-01 | 98.3% | 99.1% |
| 3891705 | 883.1.1.1 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › LBP_BPI_CETP | 0.61 | 46.0 | 3.88e-01 | 80.9% | 75.1% |
| 3438809 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.58 | 42.0 | 3.76e-01 | 77.4% | 100.0% |
| 4514345 | 274.1.1.50 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits › Spore_YunB | 0.57 | 44.0 | 4.09e-01 | 81.7% | 94.5% |
| 5018204 | 7520.1.1.0 ↗ | a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like | 0.55 | 39.0 | 3.53e-01 | 73.9% | 93.3% |
| 3287648 | 11.13.1.3 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Leukocidin-like › Leukocidin-like › MspA | 0.54 | 45.0 | 3.89e-01 | 92.2% | 89.2% |
| 3964155 | 5084.1.1.0 ↗ | beta barrels › Outer membrane meander beta-barrels › OMPA-like › OMPA-like | 0.54 | 48.0 | 3.70e-01 | 100.0% | 68.4% |
| 4003909 | 883.1.1.0 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like | 0.53 | 39.0 | 3.50e-01 | 79.1% | 87.4% |
| 166738 | 11.13.1.3 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Leukocidin-like › Leukocidin-like › MspA | 0.53 | 44.0 | 4.24e-01 | 91.3% | 87.1% |
| 3399449 | 883.1.1.32 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › JHBP, Grp7_allergen | 0.52 | 43.0 | 3.03e-01 | 90.4% | 57.1% |
| 3586859 | 11.4.1.2 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Antigen MPT63/MPB63 (immunoprotective extracellular protein) › Antigen MPT63/MPB63 (immunoprotective extracellular protein) › DUF4352 | 0.52 | 44.0 | 4.47e-01 | 91.3% | 96.5% |
| 3911618 | 277.1.1.1 ↗ | a+b two layers › PX domain › PX domain › PX domain › PX | 0.52 | 40.0 | 3.46e-01 | 80.9% | 80.6% |
| 3285785 | 11.13.1.3 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Leukocidin-like › Leukocidin-like › MspA | 0.51 | 43.0 | 3.81e-01 | 92.2% | 89.7% |
D2
high
residues 296-377
Domain cluster:
rep: polyprotein__YP_009666886__Leanyer_virus__999729__D1233-1338
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01589.22 best | Alpha_E1_glycop | 78.2 | 7.80e-22 | 100.0% | 15.3% |
D3
medium
residues 44-118