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E1a_19K

Euk-Vir

Equine_adenovirus_2

E1a_19K__YP_009162341__Equine_adenovirus_2__67603

Identity

Accession:
YP_009162341 ↗
Protein ID:
E1a_19K
Kingdom:
euk

Quality

86.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 37-127
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01691.22 best Adeno_E1B_19K 76.7 1.80e-21 100.0% 64.4%
CATH (30)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6xy4A01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.78 66.0 5.94e-01 100.0% 67.5%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.66 47.0 4.48e-01 73.6% 68.9%
4flbA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 50.0 4.52e-01 92.3% 58.0%
1ldjA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.65 50.0 4.65e-01 82.4% 86.1%
8alzB08 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.65 52.0 4.68e-01 89.0% 100.0%
6whbA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.61 49.0 3.57e-01 90.1% 50.5%
3mnlB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 53.0 4.31e-01 100.0% 62.6%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 44.0 4.05e-01 76.9% 80.3%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.60 42.0 4.09e-01 73.6% 86.8%
1qqtA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.60 47.0 4.10e-01 84.6% 73.9%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.60 42.0 3.89e-01 73.6% 73.9%
1e9rA02 1.10.8.80 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Magnesium chelatase subunit I, C-Terminal domain 0.59 43.0 4.05e-01 76.9% 74.3%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 42.0 4.20e-01 78.0% 94.7%
2w31A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 47.0 4.14e-01 97.8% 72.4%
5gl7A01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.57 43.0 3.66e-01 84.6% 64.5%
3au4A01 1.25.40.530 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain 0.56 48.0 3.86e-01 98.9% 84.2%
1tu9A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 48.0 4.34e-01 98.9% 77.9%
2lt3A01 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.56 39.0 3.87e-01 73.6% 100.0%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.56 41.0 3.77e-01 76.9% 77.3%
4hs2A00 1.25.40.420 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.55 36.0 4.08e-01 87.9% 95.3%
7ldgA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.55 44.0 3.38e-01 87.9% 52.3%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.54 38.0 3.93e-01 74.7% 97.6%
2imiB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 39.0 3.42e-01 87.9% 50.0%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.54 43.0 3.90e-01 91.2% 84.8%
4q5nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 43.0 4.05e-01 90.1% 92.0%
2juaA00 1.20.1480.30 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein 0.53 40.0 3.85e-01 79.1% 83.3%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.52 37.0 3.62e-01 74.7% 69.0%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.52 41.0 4.06e-01 89.0% 89.1%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 36.0 3.05e-01 73.6% 69.7%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.51 39.0 3.61e-01 90.1% 62.7%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3491658 5000.3.1.1 alpha arrays › Toxins' membrane translocation domains › Bcl-2 inhibitors of programmed cell death › Bcl-2 inhibitors of programmed cell death › Bcl-2 0.77 67.0 5.44e-01 100.0% 52.1%
3056394 1176.1.1.1 alpha arrays › Nitrogenase vanadium-iron protein delta chain › Nitrogenase vanadium-iron protein delta chain › Nitrogenase vanadium-iron protein delta chain › AnfG_VnfG 0.72 52.0 4.79e-01 76.9% 93.3%
4983680 7064.1.1.0 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 0.67 50.0 4.32e-01 78.0% 96.4%
4021609 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.67 56.0 4.10e-01 91.2% 59.3%
3962027 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.64 51.0 4.43e-01 86.8% 80.0%
5016694 7064.1.1.1 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 0.63 45.0 3.88e-01 76.9% 87.3%
3969668 3758.2.1.1 alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.62 44.0 3.36e-01 74.7% 80.0%
3794988 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.61 43.0 3.88e-01 73.6% 75.2%
1157315 4983.1.1.2 alpha superhelices › Indoleamine 2,3-dioxygenase N-terminal subdomain › Indoleamine 2,3-dioxygenase N-terminal subdomain › Indoleamine 2,3-dioxygenase N-terminal subdomain › PrnB 0.60 46.0 4.30e-01 84.6% 85.6%
3201430 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 45.0 4.27e-01 81.3% 85.5%
5000432 101.1.17.1 alpha arrays › HTH › HTH › FF domain › Ribosomal_S17e 0.59 42.0 4.30e-01 75.8% 86.7%
4976784 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.59 46.0 4.31e-01 82.4% 80.0%
5054956 7064.1.1.0 alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 0.59 43.0 4.01e-01 78.0% 72.5%
4246272 3921.1.1.0 alpha complex topology › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D › Na(+)-translocating NADH-quinone reductase subunit D 0.59 42.0 3.43e-01 75.8% 54.4%
4509261 109.4.1.464 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exportin-T 0.57 48.0 3.43e-01 91.2% 46.5%
3633170 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.57 52.0 4.73e-01 100.0% 80.0%
3505950 633.1.1.0 alpha bundles › Bromodomain-like › Bromodomain › Bromodomain 0.57 43.0 4.31e-01 85.7% 82.2%
3402009 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.57 48.0 3.27e-01 96.7% 42.0%
3445477 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.56 42.0 3.50e-01 78.0% 71.9%
4193771 109.4.1.464 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exportin-T 0.56 46.0 3.42e-01 89.0% 38.7%
3498569 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.56 48.0 4.66e-01 97.8% 100.0%
56761 150.3.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine 0.56 40.0 3.56e-01 76.9% 87.8%
5038437 604.39.1.2 alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › BioY 0.55 47.0 3.78e-01 96.7% 63.7%
4587181 109.4.1.464 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exportin-T 0.55 49.0 3.55e-01 98.9% 41.2%
3380671 5050.1.1.8 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 0.55 47.0 3.98e-01 97.8% 70.0%
3994623 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.55 42.0 3.95e-01 81.3% 81.8%
3976707 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 45.0 3.67e-01 96.7% 64.6%
4955945 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.54 47.0 3.89e-01 98.9% 69.4%
3187422 109.4.1.464 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exportin-T 0.52 44.0 3.23e-01 96.7% 49.5%
5072485 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 45.0 3.55e-01 100.0% 57.9%
5012039 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.50 43.0 2.98e-01 100.0% 97.0%
3247069 633.1.1.1 alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain 0.50 37.0 3.25e-01 79.1% 58.6%