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E25
Euk-VirMurid_betaherpesvirus_8
E25__YP_007016428__Murid_betaherpesvirus_8__1261657
Identity
- Accession:
- YP_007016428 ↗
- Protein ID:
- E25
- Kingdom:
- euk
Quality
68.4
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Muromegalovirus›
Murid_betaherpesvirus_8
TaxID: 1261657
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 277-383
Domain cluster:
rep: tegument_protein_UL25__YP_004940051__Aotine_betaherpesvirus_1__50290__D159-246
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04637.17 best | Herpes_pp85 | 34.1 | 1.40e-08 | 97.2% | 18.3% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ezqA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.54 | 39.0 | 3.87e-01 | 75.7% | 83.5% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1828346 | 1063.1.1.1 ↗ | alpha complex topology › Tegument protein U14 › Tegument protein U14 › Tegument protein U14 › Herpes_pp85 | 0.91 | 87.0 | 5.51e-01 | 100.0% | 24.6% |
| 3633523 | 5001.1.1.80 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Dicty_CAR | 0.60 | 44.0 | 3.49e-01 | 75.7% | 59.0% |
| 4368947 | 141.1.1.6 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › HEPPP_synt_1 | 0.56 | 39.0 | 3.03e-01 | 72.0% | 87.6% |
| None | — | 0.52 | 40.0 | 2.93e-01 | 84.1% | 65.8% |
D2
medium
residues 384-507
Domain cluster:
rep: tegument_protein_UL25__YP_004940051__Aotine_betaherpesvirus_1__50290__D247-382
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6z4xA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.55 | 45.0 | 4.18e-01 | 88.7% | 93.5% |
| 2fp1B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.55 | 39.0 | 3.57e-01 | 73.4% | 87.2% |
| 1zcdA00 | 1.20.1530.10 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain | 0.54 | 41.0 | 2.99e-01 | 80.6% | 97.3% |
| 1bucA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.54 | 33.0 | 3.32e-01 | 73.4% | 58.5% |
| 3lvyE01 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.53 | 43.0 | 3.97e-01 | 87.9% | 78.2% |
| 2gmyD00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.53 | 43.0 | 4.09e-01 | 87.9% | 86.9% |
| 6l1xA01 | 1.20.210.10 | Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain | 0.53 | 42.0 | 2.82e-01 | 85.5% | 54.2% |
| 2gbbB00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.51 | 38.0 | 3.55e-01 | 87.1% | 62.6% |
| 2fozA00 | 1.10.4080.10 | Mainly Alpha › Orthogonal Bundle › ADP-ribosylglycohydrolase fold › ADP-ribosylation/Crystallin J1 | 0.50 | 41.0 | 3.12e-01 | 91.9% | 99.7% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1828346 | 1063.1.1.1 ↗ | alpha complex topology › Tegument protein U14 › Tegument protein U14 › Tegument protein U14 › Herpes_pp85 | 0.80 | 74.0 | 4.87e-01 | 100.0% | 27.0% |
| 3944754 | 608.1.1.1 ↗ | alpha arrays › AhpD-like › AhpD-like › AhpD-like › CMD | 0.54 | 44.0 | 3.92e-01 | 87.9% | 71.3% |
| 3728784 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.53 | 35.0 | 3.84e-01 | 86.3% | 82.0% |
| 3471942 | 5051.1.1.0 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like | 0.52 | 42.0 | 2.95e-01 | 89.5% | 82.8% |
| 3796774 | 5059.1.1.34 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA, Nuc_sug_transp | 0.52 | 42.0 | 3.11e-01 | 87.9% | 78.5% |
| 3823125 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.51 | 41.0 | 3.89e-01 | 86.3% | 98.7% |
D3
medium
residues 525-645
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 32.0 | 2.90e-01 | 71.1% | 32.1% |
| 3o3mB01 | 1.20.1270.370 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.62 | 30.0 | 3.22e-01 | 90.1% | 51.5% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 33.0 | 3.07e-01 | 85.1% | 40.8% |
| 4ivfA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 38.0 | 3.87e-01 | 85.1% | 63.8% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.59 | 31.0 | 3.60e-01 | 71.9% | 70.6% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.53 | 42.0 | 4.04e-01 | 83.5% | 82.1% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.52 | 35.0 | 3.17e-01 | 75.2% | 51.6% |
| 2xl4A00 | 1.20.120.1420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain | 0.51 | 41.0 | 3.88e-01 | 86.0% | 90.5% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3215465 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.71 | 33.0 | 3.30e-01 | 70.2% | 42.3% |
| 4836806 | 1063.1.1.1 ↗ | alpha complex topology › Tegument protein U14 › Tegument protein U14 › Tegument protein U14 › Herpes_pp85 | 0.70 | 65.0 | 4.38e-01 | 98.3% | 31.3% |
| 4295566 | 4002.1.1.4 ↗ | alpha bundles › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › DHQS_C | 0.57 | 49.0 | 4.28e-01 | 95.9% | 95.8% |
| 1030741 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.56 | 37.0 | 3.48e-01 | 78.5% | 55.2% |
| 4107364 | 4002.1.1.4 ↗ | alpha bundles › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › DHQS_C | 0.53 | 46.0 | 4.10e-01 | 99.2% | 96.1% |
| 3609189 | 192.29.1.19 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon | 0.51 | 36.0 | 3.20e-01 | 73.6% | 77.7% |
| 3974898 | 601.4.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TarH | 0.51 | 38.0 | 3.33e-01 | 77.7% | 67.4% |