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E2

Euk-Vir

Macaca_fascicularis_papillomavirus_2

E2__YP_004646334__Macaca_fascicularis_papillomavirus_2__915424

Identity

Accession:
YP_004646334 ↗
Protein ID:
E2
Kingdom:
euk

Quality

75.4 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Betapapillomavirus› Macaca_fascicularis_papillomavirus_2

TaxID: 915424

Cluster

View cluster (48 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 370-453
PDB
Domain cluster: rep: E2__YP_009272701__Sparus_aurata_papillomavirus_1__1885928__D227-298
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00511.23 best PPV_E2_C 106.1 1.20e-30 95.2% 98.8%
D2 medium residues 1-97
PDB
Domain cluster: rep: E2_regulatory_protein__YP_002308360__Caretta_caretta_papillomavirus_1__485241__D3-95
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00508.23 best PPV_E2_N 132.0 2.50e-38 100.0% 48.5%
D3 medium residues 103-195
PDB
Domain cluster: rep: E2__YP_009252394__Cervus_papillomavirus_2__1434070__D104-195
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00508.23 best PPV_E2_N 118.0 5.00e-34 100.0% 46.0%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qqhA00 2.170.200.10 Mainly Beta › Beta Complex › Regulatory Protein E2; Chain: A; Domain 2 › Papillomavirus E2 early protein domain 0.98 96.0 7.97e-01 100.0% 64.6%
2jeuA02 2.170.200.10 Mainly Beta › Beta Complex › Regulatory Protein E2; Chain: A; Domain 2 › Papillomavirus E2 early protein domain 0.91 87.0 8.44e-01 100.0% 93.1%
3f6zB01 2.40.128.200 Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor 0.58 37.0 4.01e-01 74.2% 75.9%
4r8tB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.58 36.0 3.98e-01 89.2% 79.5%
2vy0B00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.54 44.0 3.29e-01 91.4% 55.1%
3m9qA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.54 31.0 3.47e-01 73.1% 72.2%
1lfoA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 37.0 3.37e-01 78.5% 52.8%
4innA00 2.40.128.520 Mainly Beta › Beta Barrel › Lipocalin › 0.54 40.0 3.49e-01 80.6% 71.2%
7t8tA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.53 37.0 3.38e-01 75.3% 98.5%
2byoA00 2.50.20.20 Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › 0.52 39.0 3.24e-01 81.7% 91.8%
2ox7A02 2.30.30.290 Mainly Beta › Roll › SH3 type barrels. › YopX-like domains 0.52 30.0 3.35e-01 72.0% 73.9%
4hwmA00 2.40.128.500 Mainly Beta › Beta Barrel › Lipocalin › YedD-like protein 0.52 37.0 3.43e-01 74.2% 59.0%
1p6pA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 35.0 3.26e-01 80.6% 53.6%
6pxcA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.51 34.0 3.30e-01 88.2% 59.6%
4azpA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 37.0 3.30e-01 81.7% 53.0%
5hmaA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.51 35.0 3.40e-01 90.3% 63.5%
3ge2A00 2.40.128.50 Mainly Beta › Beta Barrel › Lipocalin › 0.51 31.0 3.20e-01 74.2% 62.9%
2fmlA02 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.50 35.0 2.91e-01 73.1% 80.5%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2083 52.1.1.1 ↗ beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N 0.98 96.0 7.97e-01 100.0% 64.6%
2084 52.1.1.1 ↗ beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N 0.97 88.0 6.64e-01 93.5% 44.8%
262552 52.1.1.1 ↗ beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N 0.95 90.0 8.82e-01 100.0% 92.9%
1581082 52.1.1.1 ↗ beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N 0.92 88.0 8.52e-01 100.0% 92.2%
3966647 9.11.1.0 ↗ beta barrels › Lipocalins/Streptavidin › YdhA-like › YdhA-like 0.59 38.0 3.78e-01 74.2% 63.2%
169848 9.11.1.1 ↗ beta barrels › Lipocalins/Streptavidin › YdhA-like › YdhA-like › MliC 0.58 37.0 3.78e-01 74.2% 64.5%
3812573 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.58 40.0 2.98e-01 71.0% 74.6%
3410370 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.58 32.0 3.60e-01 74.2% 70.0%
4443818 2004.1.1.42 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE 0.55 45.0 2.93e-01 89.2% 58.2%
5080798 4.17.1.0 ↗ beta barrels › SH3 › GatD N-terminal domain-like › GatD N-terminal domain-like 0.55 30.0 3.31e-01 73.1% 64.0%
4478186 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.55 23.0 3.06e-01 73.1% 71.1%
3499758 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.55 41.0 4.31e-01 78.5% 92.9%
2552758 9.1.1.24 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin_7 0.54 38.0 3.36e-01 80.6% 49.6%
134180 10.1.1.11 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Glyco_hydro_16 0.54 44.0 3.28e-01 92.5% 55.3%
3894563 9.1.1.24 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin_7 0.52 36.0 3.27e-01 81.7% 52.3%
3629488 214.1.1.0 ↗ a+b two layers › SH2 › SH2 › SH2 0.51 35.0 3.27e-01 81.7% 57.4%
3415072 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.51 36.0 3.17e-01 78.5% 49.3%
3556710 9.1.1.24 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin_7 0.51 36.0 3.28e-01 80.6% 53.9%
3859895 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.51 37.0 2.53e-01 78.5% 30.9%
3567966 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.50 37.0 3.69e-01 81.7% 75.8%
3520059 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.50 32.0 3.01e-01 77.4% 50.0%