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E2

Euk-Vir

Human_papillomavirus_154

E2__YP_008083734__Human_papillomavirus_154__1195796

Identity

Accession:
YP_008083734 ↗
Protein ID:
E2
Kingdom:
euk

Quality

77.1 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Gammapapillomavirus› Human_papillomavirus_154

TaxID: 1195796

Cluster

View cluster (33 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-99
PDB
Domain cluster: rep: E2_regulatory_protein__YP_002308360__Caretta_caretta_papillomavirus_1__485241__D3-95
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00508.23 best PPV_E2_N 120.8 7.20e-35 100.0% 47.5%
D2 high residues 312-388
PDB
Domain cluster: rep: E2__YP_009272701__Sparus_aurata_papillomavirus_1__1885928__D227-298
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00511.23 best PPV_E2_C 82.4 2.90e-23 100.0% 95.0%
D3 medium residues 148-199
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00508.23 best PPV_E2_N 51.7 1.00e-13 100.0% 25.0%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qqhA00 2.170.200.10 Mainly Beta › Beta Complex › Regulatory Protein E2; Chain: A; Domain 2 › Papillomavirus E2 early protein domain 0.95 87.0 6.09e-01 100.0% 35.4%
2jeuA02 2.170.200.10 Mainly Beta › Beta Complex › Regulatory Protein E2; Chain: A; Domain 2 › Papillomavirus E2 early protein domain 0.84 75.0 5.97e-01 100.0% 52.5%
1x9yA01 3.10.500.10 Alpha Beta › Roll › prostaphopain b, domain 1 › Staphopain proregion domain 0.69 48.0 3.29e-01 100.0% 22.4%
4ojuA00 3.80.10.10 Alpha Beta › Alpha-Beta Horseshoe › Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) › Ribonuclease Inhibitor 0.62 41.0 3.02e-01 76.9% 24.6%
3hoiA00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.62 50.0 3.37e-01 98.1% 24.4%
3id6A01 3.30.420.220 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.60 44.0 3.63e-01 90.4% 41.5%
3dr2A00 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.59 49.0 3.10e-01 98.1% 21.7%
4m52A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 40.0 2.69e-01 78.8% 80.2%
3v9fA02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 40.0 2.54e-01 90.4% 41.8%
8cukB01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 41.0 2.55e-01 92.3% 81.6%
4c5wA01 3.30.2020.30 Alpha Beta › 2-Layer Sandwich › NE0471 N-terminal domain-like › 0.51 38.0 3.28e-01 88.5% 69.1%
1a78A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.51 35.0 2.71e-01 88.5% 29.1%
3pvlA04 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.50 40.0 3.34e-01 92.3% 72.7%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2083 52.1.1.1 ↗ beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N 0.95 87.0 6.09e-01 100.0% 35.4%
1581082 52.1.1.1 ↗ beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N 0.86 78.0 6.15e-01 100.0% 52.0%
4235772 243.3.1.11 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › Staphopain_pro 0.68 46.0 3.19e-01 100.0% 22.0%
3799904 4.1.1.315 ↗ beta barrels › SH3 › SH3 › SH3 › SH3_12, XRN1_D1 0.60 48.0 2.95e-01 98.1% 46.3%
5036089 3407.1.1.2 ↗ mixed a+b and a/b › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop5_56-rel_N_Arc 0.58 49.0 3.81e-01 100.0% 88.0%
4658740 220.1.1.82 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_6 0.57 36.0 3.21e-01 82.7% 41.3%
4946976 3407.1.1.5 ↗ mixed a+b and a/b › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.57 48.0 3.54e-01 98.1% 84.8%
3468128 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 44.0 2.78e-01 88.5% 40.9%
1320681 64.2.1.1 ↗ beta meanders › WW domain-like › Peptidoglycan hydrolase LytB WW-like domain › Peptidoglycan hydrolase LytB WW-like domain › WW_like 0.56 36.0 3.61e-01 94.2% 62.3%
4000029 5.1.4.139 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40_2 0.56 43.0 2.74e-01 92.3% 20.3%
4953660 3407.1.1.2 ↗ mixed a+b and a/b › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop5_56-rel_N_Arc 0.55 45.0 3.55e-01 98.1% 91.7%
4017465 928.1.1.0 ↗ few secondary structure elements › Bubble protein › Bubble protein › Bubble protein 0.55 37.0 3.75e-01 84.6% 75.5%
3478678 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.53 35.0 3.26e-01 88.5% 48.0%
4683204 101.35.1.5 ↗ alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH1 0.53 36.0 3.01e-01 71.2% 64.8%
3185909 394.1.1.2 ↗ few secondary structure elements › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › CBM_19 0.52 40.0 4.07e-01 92.3% 92.0%
4176722 719.2.1.1 ↗ beta barrels › XRCC4, N-terminal domain-like › NE0471 N-terminal domain-like › NE0471 N-terminal domain-like › GBBH-like_N 0.52 39.0 3.29e-01 86.5% 63.0%
5013411 3407.1.1.2 ↗ mixed a+b and a/b › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop5_56-rel_N_Arc 0.52 43.0 3.41e-01 100.0% 90.0%
3581592 2004.1.1.30 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C 0.52 44.0 2.95e-01 98.1% 90.0%
3591613 633.23.1.23 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › Amastin 0.51 38.0 2.74e-01 88.5% 63.8%