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E2

Euk-Vir

Eidolon_helvum_papillomavirus_1

E2__YP_009507288__Eidolon_helvum_papillomavirus_1__1163701

Identity

Accession:: YP_009507288 ↗
Protein ID:: E2
Kingdom:: euk

Quality

82.9 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Papovaviricetes› Zurhausenvirales› Papillomaviridae› Dyoupsilonpapillomavirus› Eidolon_helvum_papillomavirus_1

TaxID: 1163701

Cluster

View cluster (40 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-98

PDB

Domain cluster: rep: E2_regulatory_protein__YP_002308360__Caretta_caretta_papillomavirus_1__485241__D3-95

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00508.23 best	PPV_E2_N	117.8	5.90e-34	98.0%	47.5%

D2 high residues 112-200

PDB

Domain cluster: rep: E2__YP_009252394__Cervus_papillomavirus_2__1434070__D104-195

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00508.23 best	PPV_E2_N	92.9	2.40e-26	100.0%	43.0%

CATH (13)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1qqhA00	2.170.200.10	Mainly Beta › Beta Complex › Regulatory Protein E2; Chain: A; Domain 2 › Papillomavirus E2 early protein domain	0.95	90.0	7.39e-01	98.9%	60.4%
2jeuA02	2.170.200.10	Mainly Beta › Beta Complex › Regulatory Protein E2; Chain: A; Domain 2 › Papillomavirus E2 early protein domain	0.93	88.0	8.36e-01	100.0%	87.1%
4hwmA00	2.40.128.500	Mainly Beta › Beta Barrel › Lipocalin › YedD-like protein	0.66	35.0	3.22e-01	70.8%	39.3%
3f6zB01	2.40.128.200	Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor	0.65	35.0	3.69e-01	70.8%	57.0%
1x5hA00	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.64	43.0	3.75e-01	97.8%	46.2%
3u9sE04	3.30.700.40	Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin ›	0.59	31.0	2.78e-01	77.5%	33.6%
2w5eA02	2.40.10.10	Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases	0.57	35.0	3.75e-01	94.4%	71.6%
4innA00	2.40.128.520	Mainly Beta › Beta Barrel › Lipocalin ›	0.56	37.0	3.20e-01	77.5%	41.8%
2j8gA03	2.20.120.10	Mainly Beta › Single Sheet › Multimodular pneumococcal cell wall endolysin, domain 3 › Multimodular pneumococcal cell wall endolysin, domain 3	0.53	30.0	3.43e-01	70.8%	81.0%
4eqvA02	2.60.120.560	Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1	0.52	44.0	3.63e-01	97.8%	76.7%
6c1zA00	2.40.128.20	Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain	0.52	35.0	3.10e-01	70.8%	84.8%
4azpA00	2.40.128.20	Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain	0.51	36.0	3.17e-01	73.0%	84.3%
1wzlA01	2.60.40.10	Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins	0.50	42.0	3.78e-01	97.8%	66.9%

ECOD (15)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2084	52.1.1.1 ↗	beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N	0.97	84.0	6.24e-01	91.0%	41.2%
2083	52.1.1.1 ↗	beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N	0.95	90.0	7.39e-01	98.9%	60.4%
262552	52.1.1.1 ↗	beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N	0.95	89.0	8.56e-01	100.0%	87.9%
1581082	52.1.1.1 ↗	beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N	0.91	86.0	8.13e-01	100.0%	86.3%
3934469	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.59	43.0	3.92e-01	97.8%	56.0%
5038601	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.55	39.0	4.05e-01	96.6%	78.8%
134180	10.1.1.11 ↗	beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Glyco_hydro_16	0.55	46.0	3.34e-01	93.3%	41.7%
3506907	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.53	32.0	3.11e-01	70.8%	51.0%
4478186	4.1.1.0 ↗	beta barrels › SH3 › SH3 › SH3	0.53	28.0	3.55e-01	88.8%	97.8%
2438877	9.1.1.0 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins	0.52	35.0	3.10e-01	70.8%	84.8%
3996508	9.1.1.0 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins	0.52	36.0	3.08e-01	73.0%	83.8%
2265	702.1.1.4 ↗	beta duplicates or obligate multimers › beta-hairpin stack › beta-hairpin stack › beta-hairpin stack	0.52	30.0	2.57e-01	71.9%	32.9%
3215657	9.1.1.1 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin	0.51	35.0	3.08e-01	70.8%	86.7%
3894563	9.1.1.24 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin_7	0.51	35.0	3.14e-01	71.9%	85.2%
3273105	9.1.1.0 ↗	beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins	0.50	34.0	3.25e-01	70.8%	59.0%

D3 high residues 312-388

PDB

Domain cluster: rep: E2__YP_009272701__Sparus_aurata_papillomavirus_1__1885928__D227-298

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00511.23 best	PPV_E2_C	84.1	9.10e-24	97.4%	96.2%