Back to structures

E2

Euk-Vir

Leptonychotes_weddellii_papillomavirus_6

E2__YP_009553596__Leptonychotes_weddellii_papillomavirus_6__2077307

Identity

Accession:
YP_009553596 ↗
Protein ID:
E2
Kingdom:
euk

Quality

79.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-98
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00508.23 best PPV_E2_N 119.1 2.40e-34 99.0% 48.5%
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dtoA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.98 95.0 9.40e-01 100.0% 96.1%
2jexA01 1.10.287.30 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 0.96 89.0 9.06e-01 96.9% 99.0%
2azjA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.74 53.0 3.79e-01 74.5% 42.4%
4c91A03 1.20.58.2150 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 62.0 5.03e-01 90.8% 55.3%
2qvaA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.69 49.0 4.43e-01 72.4% 77.5%
3c1yA02 1.20.1260.110 Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region 0.69 63.0 5.43e-01 99.0% 94.6%
4nleA01 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.69 63.0 4.60e-01 100.0% 48.4%
6nplA01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.69 55.0 3.51e-01 84.7% 81.6%
4mhlA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.68 59.0 4.92e-01 91.8% 72.7%
4fp4A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.68 53.0 3.91e-01 82.7% 57.6%
8hk0B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.68 57.0 5.07e-01 91.8% 74.6%
2wdqD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.67 56.0 5.51e-01 89.8% 100.0%
7eu3E01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 53.0 5.61e-01 92.9% 98.9%
3u64A00 1.25.40.920 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TRAP transporter T-component 0.66 53.0 3.87e-01 87.8% 32.8%
2l6hA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.66 58.0 5.03e-01 100.0% 70.8%
3d19B00 1.20.1260.120 Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 0.65 57.0 4.21e-01 98.0% 82.1%
4oo2A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.65 52.0 4.13e-01 87.8% 68.4%
7c4sB01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.65 58.0 4.20e-01 100.0% 40.9%
6vq6G02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.64 46.0 3.67e-01 73.5% 61.4%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.64 52.0 4.33e-01 86.7% 55.0%
7smtA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.64 52.0 4.23e-01 100.0% 48.3%
7um4A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 56.0 4.22e-01 100.0% 47.0%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 46.0 3.55e-01 76.5% 77.0%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.62 56.0 5.52e-01 100.0% 94.1%
1w99A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.62 52.0 4.28e-01 90.8% 60.1%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 53.0 4.45e-01 94.9% 57.8%
7xxiA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 55.0 3.94e-01 100.0% 40.0%
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.61 49.0 4.67e-01 83.7% 84.8%
2d9dA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.60 45.0 4.70e-01 100.0% 87.6%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 49.0 5.11e-01 87.8% 95.6%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.58 50.0 4.48e-01 99.0% 67.7%
4doyA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.57 52.0 4.22e-01 100.0% 60.7%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 52.0 5.15e-01 99.0% 97.1%
3ccyA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 46.0 4.03e-01 88.8% 95.9%
3purA03 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 44.0 4.22e-01 82.7% 81.8%
4rfsS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.54 47.0 3.83e-01 96.9% 57.2%
6lumD01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.54 45.0 4.18e-01 91.8% 91.2%
3ubkB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 39.0 3.61e-01 77.6% 76.8%
3m1mA03 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.53 37.0 3.57e-01 82.7% 64.5%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 49.0 4.54e-01 100.0% 86.8%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 48.0 3.90e-01 99.0% 73.4%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 46.0 4.09e-01 99.0% 99.3%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 46.0 4.01e-01 99.0% 94.0%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.51 45.0 3.58e-01 99.0% 74.6%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
146673 3017.1.1.1 alpha bundles › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › PPV_E2_N 0.99 95.0 9.63e-01 99.0% 100.0%
2084 52.1.1.1 beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N 0.98 95.0 7.24e-01 100.0% 50.5%
1581081 3017.1.1.1 alpha bundles › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › PPV_E2_N 0.96 89.0 9.11e-01 96.9% 100.0%
3494918 109.4.1.37 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 0.80 70.0 4.63e-01 91.8% 27.8%
3328692 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.80 66.0 5.73e-01 87.8% 70.3%
3801151 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.79 68.0 5.28e-01 91.8% 59.3%
4020083 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.78 65.0 5.66e-01 87.8% 69.3%
4945390 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.77 61.0 5.41e-01 82.7% 63.7%
3240691 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.77 64.0 5.63e-01 86.7% 68.9%
3837728 3843.1.1.0 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.75 70.0 6.15e-01 98.0% 83.0%
3395959 5086.1.1.166 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PEX11 0.72 58.0 5.89e-01 85.7% 100.0%
3490233 109.26.1.6 alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › TPR_NUP160_120_M 0.70 52.0 4.10e-01 77.6% 42.0%
3714005 5054.1.1.61 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO 0.69 58.0 4.26e-01 89.8% 67.8%
3724548 611.7.1.10 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Helo_like_N 0.67 49.0 4.32e-01 74.5% 95.6%
3714706 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 59.0 4.58e-01 95.9% 46.7%
4449533 3843.1.1.1 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 0.66 52.0 5.35e-01 92.9% 89.5%
3377989 174.1.1.49 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7733 0.65 54.0 4.14e-01 90.8% 80.9%
3768533 109.4.1.2144 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27737, PF30504 0.65 49.0 3.12e-01 79.6% 77.0%
3569625 604.12.1.4 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.64 54.0 4.73e-01 90.8% 84.1%
3592028 109.4.1.218 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP 0.64 49.0 3.99e-01 81.6% 46.5%
3225714 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.64 53.0 4.48e-01 87.8% 81.3%
3449605 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.63 45.0 4.37e-01 74.5% 76.4%
3227811 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.63 55.0 4.81e-01 100.0% 69.7%
3237156 604.12.1.4 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.63 53.0 4.75e-01 90.8% 87.4%
3217635 3684.1.1.30 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF29678 0.62 54.0 4.60e-01 100.0% 63.5%
3251538 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 51.0 3.47e-01 87.8% 27.3%
3216129 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.61 50.0 4.61e-01 88.8% 76.0%
2387822 604.38.1.0 alpha bundles › Spectrin repeat-like › Legionella effector SdeA 3-helical bundle › Legionella effector SdeA 3-helical bundle 0.61 50.0 4.90e-01 100.0% 81.0%
4263262 109.4.1.1621 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27751 0.60 49.0 3.29e-01 90.8% 24.5%
4957771 5069.1.3.137 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF7521 0.60 50.0 5.16e-01 91.8% 100.0%
3233698 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.60 52.0 4.74e-01 91.8% 86.4%
3220791 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.60 50.0 4.03e-01 90.8% 50.5%
3937918 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.60 51.0 4.65e-01 91.8% 82.3%
3514005 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.60 48.0 3.79e-01 87.8% 68.1%
3229891 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.60 51.0 4.57e-01 91.8% 85.2%
3586162 5057.1.1.0 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.59 50.0 4.63e-01 91.8% 83.2%
3801203 109.4.1.2247 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, TPR_6, TPR_8, TPR_19 0.59 48.0 2.96e-01 91.8% 13.9%
3793986 604.7.1.7 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › Mitofilin 0.56 52.0 4.66e-01 100.0% 90.4%
3673003 3922.1.1.254 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › NET2A_C 0.56 52.0 4.77e-01 100.0% 88.8%
5061118 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.56 50.0 4.68e-01 100.0% 79.0%
3528346 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 51.0 4.27e-01 100.0% 61.2%
3499315 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 47.0 4.47e-01 100.0% 78.0%
3506302 109.4.1.80 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRN3 0.55 42.0 3.36e-01 83.7% 72.4%
3927597 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.54 49.0 4.63e-01 100.0% 89.2%
3492595 192.29.1.11 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA 0.54 47.0 4.41e-01 99.0% 84.0%
3936985 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.53 47.0 4.07e-01 99.0% 67.1%
4025809 604.6.1.22 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 0.53 45.0 4.40e-01 100.0% 82.7%
3961339 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.51 41.0 3.71e-01 87.8% 96.3%
3630205 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 44.0 4.11e-01 93.9% 87.5%
D2 high residues 115-196
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00508.23 best PPV_E2_N 72.9 3.30e-20 100.0% 41.0%
D3 high residues 358-438
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00511.23 best PPV_E2_C 74.6 8.00e-21 96.3% 97.5%