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E2_regulatory_protein
Euk-VirCaretta_caretta_papillomavirus_1
E2_regulatory_protein__YP_002308360__Caretta_caretta_papillomavirus_1__485241
Identity
- Accession:
- YP_002308360 ↗
- Protein ID:
- E2_regulatory_protein
- Kingdom:
- euk
Quality
73.1
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Papovaviricetes›
Zurhausenvirales›
Papillomaviridae›
Dyozetapapillomavirus›
Caretta_caretta_papillomavirus_1
TaxID: 485241
Cluster
View cluster (4 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-95
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00508.23 best | PPV_E2_N | 84.3 | 1.00e-23 | 100.0% | 45.5% |
CATH (64)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.98 | 96.0 | 9.21e-01 | 100.0% | 91.2% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.97 | 94.0 | 9.33e-01 | 100.0% | 96.9% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.83 | 52.0 | 4.89e-01 | 72.0% | 53.6% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.82 | 54.0 | 5.02e-01 | 72.0% | 56.4% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.82 | 56.0 | 5.45e-01 | 71.0% | 72.8% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.78 | 55.0 | 5.27e-01 | 72.0% | 70.9% |
| 3kdqA00 | 6.10.320.10 | Special › Helix non-globular › Ferritin › | 0.78 | 56.0 | 4.65e-01 | 74.2% | 97.4% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.77 | 54.0 | 5.82e-01 | 72.0% | 86.4% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.75 | 50.0 | 5.25e-01 | 71.0% | 73.3% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.75 | 54.0 | 4.96e-01 | 73.1% | 61.4% |
| 2etnB01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.75 | 52.0 | 5.73e-01 | 72.0% | 86.8% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.75 | 52.0 | 5.33e-01 | 71.0% | 78.7% |
| 3d19B00 | 1.20.1260.120 | Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 | 0.74 | 62.0 | 4.39e-01 | 89.2% | 36.3% |
| 3t98B00 | 6.10.140.1350 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 50.0 | 5.22e-01 | 71.0% | 77.9% |
| 7utzR02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.72 | 54.0 | 3.77e-01 | 78.5% | 89.4% |
| 2azjA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.70 | 54.0 | 3.81e-01 | 81.7% | 43.5% |
| 6kd7A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.69 | 53.0 | 3.60e-01 | 81.7% | 54.1% |
| 4nleA01 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.69 | 62.0 | 4.50e-01 | 100.0% | 55.5% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 53.0 | 4.75e-01 | 87.1% | 58.6% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.68 | 48.0 | 4.00e-01 | 73.1% | 93.8% |
| 6v0kA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.68 | 52.0 | 3.58e-01 | 80.6% | 28.5% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.68 | 47.0 | 4.23e-01 | 72.0% | 74.4% |
| 4fp4A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.68 | 55.0 | 4.02e-01 | 87.1% | 57.6% |
| 1s5jA04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.68 | 41.0 | 4.90e-01 | 73.1% | 93.4% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.67 | 47.0 | 3.74e-01 | 72.0% | 43.7% |
| 1v4eA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.67 | 54.0 | 3.81e-01 | 87.1% | 51.1% |
| 4xt1A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.66 | 58.0 | 4.16e-01 | 100.0% | 33.7% |
| 2lquA01 | 1.20.1420.40 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein | 0.66 | 55.0 | 4.69e-01 | 91.4% | 94.8% |
| 2q58B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.66 | 54.0 | 3.68e-01 | 88.2% | 27.4% |
| 5jfqB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.66 | 54.0 | 3.70e-01 | 87.1% | 48.4% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.66 | 50.0 | 3.87e-01 | 79.6% | 78.1% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.66 | 59.0 | 5.00e-01 | 100.0% | 63.0% |
| 2vf8B02 | 1.20.1580.10 | Mainly Alpha › Up-down Bundle › ABC transporter ATPase like fold › ABC transporter ATPase like domain | 0.66 | 48.0 | 4.02e-01 | 90.3% | 44.7% |
| 3aqbB00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.65 | 53.0 | 3.60e-01 | 87.1% | 44.5% |
| 4kk2B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.65 | 46.0 | 3.14e-01 | 78.5% | 20.8% |
| 7eu3E01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.65 | 51.0 | 5.31e-01 | 93.5% | 94.3% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.64 | 57.0 | 4.07e-01 | 100.0% | 38.6% |
| 3terA00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 44.0 | 4.04e-01 | 71.0% | 73.9% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.63 | 44.0 | 4.63e-01 | 72.0% | 89.4% |
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.63 | 52.0 | 5.01e-01 | 89.2% | 100.0% |
| 2b3tB01 | 6.10.140.1980 | Special › Helix non-globular › Helix Hairpins › | 0.63 | 40.0 | 4.66e-01 | 79.6% | 93.8% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.62 | 53.0 | 5.38e-01 | 91.4% | 95.6% |
| 2zcxA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 46.0 | 3.52e-01 | 77.4% | 51.7% |
| 4oo2A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 53.0 | 4.06e-01 | 93.5% | 42.2% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.62 | 54.0 | 5.28e-01 | 100.0% | 88.2% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.61 | 52.0 | 4.00e-01 | 91.4% | 80.5% |
| 5mdtA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 45.0 | 3.88e-01 | 79.6% | 72.4% |
| 3nftA00 | 1.20.1710.10 | Mainly Alpha › Up-down Bundle › IpaD-like › IpaD-like | 0.61 | 54.0 | 3.91e-01 | 98.9% | 91.2% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 49.0 | 4.21e-01 | 90.3% | 90.9% |
| 7smtA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.60 | 54.0 | 4.38e-01 | 98.9% | 90.2% |
| 3nyjA00 | 1.20.120.770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Amyloid precursor protein, E2 domain | 0.60 | 48.0 | 3.95e-01 | 90.3% | 91.7% |
| 1kqfC00 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.59 | 52.0 | 3.97e-01 | 98.9% | 64.8% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.58 | 50.0 | 4.05e-01 | 90.3% | 98.8% |
| 8g0lB01 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 41.0 | 2.78e-01 | 83.9% | 18.4% |
| 3swhA01 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.57 | 43.0 | 3.63e-01 | 82.8% | 87.3% |
| 3purA03 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 46.0 | 4.40e-01 | 89.2% | 82.7% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 52.0 | 5.04e-01 | 100.0% | 93.3% |
| 2ibdA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 44.0 | 3.81e-01 | 87.1% | 90.5% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 47.0 | 4.37e-01 | 95.7% | 92.4% |
| 3f0cA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 44.0 | 3.88e-01 | 92.5% | 97.9% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.53 | 40.0 | 3.83e-01 | 81.7% | 85.7% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 48.0 | 4.40e-01 | 100.0% | 84.3% |
| 2pbxA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 42.0 | 3.26e-01 | 90.3% | 40.1% |
| 2hkuB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 46.0 | 3.75e-01 | 100.0% | 67.0% |
ECOD (68)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 146673 | 3017.1.1.1 ↗ | alpha bundles › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › PPV_E2_N | 0.99 | 97.0 | 9.54e-01 | 100.0% | 95.9% |
| 2084 | 52.1.1.1 ↗ | beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N | 0.98 | 95.0 | 7.12e-01 | 100.0% | 47.9% |
| 1581081 | 3017.1.1.1 ↗ | alpha bundles › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › Alpha-helical subdomain in E2 regularoty transactivation domain › PPV_E2_N | 0.97 | 94.0 | 9.37e-01 | 100.0% | 97.9% |
| 4169065 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 57.0 | 3.82e-01 | 71.0% | 22.7% |
| 4984959 | 3758.1.1.113 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › Rad50_zn_hook | 0.80 | 55.0 | 3.65e-01 | 71.0% | 22.1% |
| 3328692 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.78 | 65.0 | 5.54e-01 | 88.2% | 67.6% |
| 3494918 | 109.4.1.37 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 | 0.78 | 68.0 | 4.49e-01 | 92.5% | 26.7% |
| 3309008 | 375.1.1.246 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rad50_zn_hook | 0.78 | 55.0 | 5.24e-01 | 72.0% | 69.5% |
| 4020083 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.77 | 64.0 | 5.51e-01 | 88.2% | 66.4% |
| 3185802 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.77 | 63.0 | 5.47e-01 | 86.0% | 65.2% |
| 5029796 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.77 | 53.0 | 4.81e-01 | 71.0% | 60.8% |
| 3396506 | 7015.1.1.1 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › DHHC | 0.77 | 64.0 | 4.86e-01 | 88.2% | 76.0% |
| 4259085 | 3755.4.1.66 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › MCPsignal | 0.76 | 53.0 | 3.63e-01 | 72.0% | 23.1% |
| 4005523 | 3860.1.1.167 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › MscS_porin | 0.75 | 50.0 | 4.10e-01 | 71.0% | 40.0% |
| 3837728 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.75 | 70.0 | 6.11e-01 | 100.0% | 80.7% |
| 3938116 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.75 | 56.0 | 4.01e-01 | 78.5% | 35.7% |
| 3589446 | 2004.1.1.301 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_27 | 0.74 | 52.0 | 3.21e-01 | 72.0% | 47.6% |
| 3258297 | 141.1.1.0 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases | 0.73 | 61.0 | 4.52e-01 | 88.2% | 67.3% |
| 3714005 | 5054.1.1.61 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › ELO | 0.73 | 62.0 | 4.44e-01 | 90.3% | 67.5% |
| 3698292 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.72 | 51.0 | 4.31e-01 | 72.0% | 53.1% |
| 5059126 | 5051.1.1.2 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease | 0.72 | 58.0 | 3.68e-01 | 86.0% | 77.8% |
| 4392393 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.72 | 53.0 | 3.76e-01 | 78.5% | 41.8% |
| 5082674 | 141.1.1.0 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases | 0.71 | 61.0 | 4.30e-01 | 90.3% | 73.2% |
| 3743175 | 630.1.1.0 ↗ | a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain | 0.71 | 59.0 | 4.72e-01 | 88.2% | 91.4% |
| 4179150 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.71 | 52.0 | 3.16e-01 | 76.3% | 17.2% |
| 3361591 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.70 | 59.0 | 5.34e-01 | 91.4% | 76.8% |
| 4957307 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.70 | 55.0 | 3.68e-01 | 82.8% | 57.6% |
| 5025856 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.70 | 53.0 | 3.62e-01 | 80.6% | 54.1% |
| 3592028 | 109.4.1.218 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP | 0.69 | 56.0 | 4.41e-01 | 86.0% | 48.1% |
| 3590280 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.68 | 53.0 | 3.60e-01 | 82.8% | 39.6% |
| 5044170 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.68 | 54.0 | 3.65e-01 | 86.0% | 41.0% |
| 4928883 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.68 | 53.0 | 3.64e-01 | 83.9% | 37.2% |
| 4023110 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.67 | 59.0 | 4.38e-01 | 93.5% | 92.3% |
| 3506207 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.67 | 48.0 | 3.17e-01 | 74.2% | 27.4% |
| 3454576 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.67 | 54.0 | 3.66e-01 | 86.0% | 45.1% |
| 3249523 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.67 | 60.0 | 5.52e-01 | 100.0% | 85.8% |
| 4934760 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.67 | 58.0 | 3.95e-01 | 91.4% | 68.0% |
| 1503525 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.66 | 58.0 | 4.16e-01 | 100.0% | 33.7% |
| 3268975 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.66 | 49.0 | 4.17e-01 | 77.4% | 87.3% |
| 3225714 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.66 | 57.0 | 4.71e-01 | 91.4% | 78.7% |
| 404756 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.65 | 53.0 | 3.60e-01 | 87.1% | 44.0% |
| 3217635 | 3684.1.1.30 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PF29678 | 0.65 | 57.0 | 4.75e-01 | 100.0% | 60.6% |
| 5061950 | 141.1.1.1 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › polyprenyl_synt | 0.65 | 53.0 | 3.67e-01 | 88.2% | 64.6% |
| 5066959 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.64 | 44.0 | 3.37e-01 | 71.0% | 31.2% |
| 3595526 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.64 | 54.0 | 4.72e-01 | 92.5% | 98.6% |
| 3500901 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.64 | 48.0 | 3.79e-01 | 79.6% | 84.2% |
| 3824606 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.63 | 53.0 | 4.30e-01 | 90.3% | 56.0% |
| 3216129 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.63 | 53.0 | 4.78e-01 | 89.2% | 72.0% |
| 3388999 | 5057.1.1.1 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb | 0.63 | 56.0 | 4.34e-01 | 94.6% | 88.4% |
| 3227811 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.62 | 55.0 | 4.69e-01 | 100.0% | 66.5% |
| 3937918 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.62 | 56.0 | 4.93e-01 | 95.7% | 80.8% |
| 3486748 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.62 | 51.0 | 4.91e-01 | 87.1% | 94.3% |
| 4967169 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.62 | 55.0 | 5.28e-01 | 100.0% | 86.7% |
| 3233698 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.62 | 55.0 | 4.93e-01 | 95.7% | 87.2% |
| 5047661 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.62 | 51.0 | 4.56e-01 | 90.3% | 67.7% |
| 3175905 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 50.0 | 3.12e-01 | 86.0% | 27.4% |
| 3586162 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.61 | 54.0 | 4.88e-01 | 95.7% | 81.6% |
| 3229891 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.60 | 55.0 | 4.82e-01 | 98.9% | 86.7% |
| 3492595 | 192.29.1.11 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA | 0.59 | 53.0 | 4.80e-01 | 100.0% | 85.6% |
| 3932144 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.58 | 49.0 | 4.54e-01 | 91.4% | 79.1% |
| 1510407 | 6171.1.1.1 ↗ | alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › JHD | 0.57 | 48.0 | 4.41e-01 | 91.4% | 94.2% |
| 3641718 | 604.5.1.52 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › DUF7610 | 0.57 | 45.0 | 4.81e-01 | 100.0% | 100.0% |
| 4941675 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.55 | 45.0 | 2.91e-01 | 91.4% | 56.3% |
| 3474716 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.55 | 48.0 | 3.22e-01 | 97.8% | 58.4% |
| 5061118 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.54 | 48.0 | 4.37e-01 | 100.0% | 79.0% |
| 3961339 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.53 | 41.0 | 3.69e-01 | 83.9% | 91.9% |
| 3459453 | 109.4.1.1257 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 | 0.53 | 35.0 | 3.32e-01 | 86.0% | 56.4% |
| 3630205 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.51 | 45.0 | 4.18e-01 | 98.9% | 87.5% |
D2
high
residues 104-143_155-202
Domain cluster:
rep: E2__YP_003622566__Bettongia_penicillata_papillomavirus_1__759701__D110-171
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00508.23 best | PPV_E2_N | 59.0 | 5.80e-16 | 100.0% | 42.0% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1qqhA00 | 2.170.200.10 | Mainly Beta › Beta Complex › Regulatory Protein E2; Chain: A; Domain 2 › Papillomavirus E2 early protein domain | 0.86 | 79.0 | 6.52e-01 | 100.0% | 59.0% |
| 2jeuA02 | 2.170.200.10 | Mainly Beta › Beta Complex › Regulatory Protein E2; Chain: A; Domain 2 › Papillomavirus E2 early protein domain | 0.82 | 74.0 | 7.05e-01 | 100.0% | 85.1% |
| 6grsA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.64 | 38.0 | 3.73e-01 | 90.9% | 53.7% |
| 1cfbA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.64 | 34.0 | 3.25e-01 | 92.0% | 41.5% |
| 3l5iA03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.63 | 33.0 | 3.33e-01 | 90.9% | 47.7% |
| 3f6zB01 | 2.40.128.200 | Mainly Beta › Beta Barrel › Lipocalin › C-type lysozyme inhibitor | 0.60 | 40.0 | 4.26e-01 | 83.0% | 75.9% |
| 2htdB00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.60 | 37.0 | 3.32e-01 | 90.9% | 44.4% |
| 7y8sB03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.60 | 32.0 | 3.31e-01 | 90.9% | 51.2% |
| 2r6vA01 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.59 | 41.0 | 3.33e-01 | 97.7% | 38.4% |
| 1yoaA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.58 | 40.0 | 3.31e-01 | 98.9% | 40.3% |
| 1uscA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.57 | 41.0 | 3.23e-01 | 98.9% | 36.5% |
| 2ecuA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.57 | 40.0 | 3.40e-01 | 97.7% | 43.6% |
| 1rz1A00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.56 | 40.0 | 3.37e-01 | 100.0% | 44.1% |
| 2ptfA01 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.55 | 34.0 | 2.88e-01 | 90.9% | 36.7% |
| 3nfwA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.55 | 40.0 | 3.16e-01 | 100.0% | 37.4% |
| 3liuA01 | 2.60.40.3160 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 31.0 | 2.86e-01 | 90.9% | 39.0% |
| 4hwmA00 | 2.40.128.500 | Mainly Beta › Beta Barrel › Lipocalin › YedD-like protein | 0.54 | 40.0 | 3.60e-01 | 79.5% | 58.1% |
| 2f4nB02 | 2.40.30.90 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Bacterial fluorinating enzyme like | 0.53 | 39.0 | 3.81e-01 | 90.9% | 72.3% |
| 2imlA01 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.53 | 33.0 | 3.07e-01 | 92.0% | 48.7% |
| 1lfoA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.52 | 38.0 | 3.37e-01 | 85.2% | 53.5% |
| 3mazA00 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.51 | 34.0 | 3.28e-01 | 92.0% | 60.6% |
| 3m9qA01 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.51 | 29.0 | 3.19e-01 | 78.4% | 68.1% |
| 1p6pA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.50 | 36.0 | 3.24e-01 | 85.2% | 53.6% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2083 | 52.1.1.1 ↗ | beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N | 0.86 | 79.0 | 6.52e-01 | 100.0% | 59.0% |
| 262552 | 52.1.1.1 ↗ | beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N | 0.85 | 77.0 | 7.35e-01 | 100.0% | 84.8% |
| 2084 | 52.1.1.1 ↗ | beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N | 0.85 | 77.0 | 5.81e-01 | 100.0% | 43.8% |
| 1581082 | 52.1.1.1 ↗ | beta sandwiches › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › E2 regulatory, transactivation domain › PPV_E2_N | 0.82 | 74.0 | 7.07e-01 | 100.0% | 84.3% |
| 5068693 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.64 | 38.0 | 3.66e-01 | 93.2% | 49.5% |
| 4929839 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.57 | 36.0 | 3.32e-01 | 93.2% | 47.8% |
| 4500974 | 1.1.5.25 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ | 0.57 | 33.0 | 3.04e-01 | 92.0% | 42.5% |
| 3246415 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.54 | 39.0 | 3.54e-01 | 96.6% | 54.4% |
| 4938346 | 1.1.5.17 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N | 0.54 | 33.0 | 2.86e-01 | 92.0% | 37.9% |
| 3520059 | 9.1.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin | 0.52 | 32.0 | 2.91e-01 | 83.0% | 43.3% |
D3
high
residues 323-400
Domain cluster:
rep: E2__YP_009272701__Sparus_aurata_papillomavirus_1__1885928__D227-298
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00511.23 best | PPV_E2_C | 57.8 | 1.40e-15 | 97.4% | 93.8% |