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E32
Euk-VirMurid_betaherpesvirus_8
E32__YP_007016436__Murid_betaherpesvirus_8__1261657
Identity
- Accession:
- YP_007016436 ↗
- Protein ID:
- E32
- Kingdom:
- euk
Quality
62.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Muromegalovirus›
Murid_betaherpesvirus_8
TaxID: 1261657
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 75-209
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06070.16 best | Herpes_UL32 | 25.5 | 3.80e-06 | 55.6% | 6.1% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.69 | 40.0 | 4.54e-01 | 84.4% | 75.5% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.68 | 41.0 | 4.15e-01 | 87.4% | 61.1% |
| 3rc3A05 | 1.20.58.1080 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 38.0 | 4.12e-01 | 87.4% | 67.3% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 41.0 | 4.26e-01 | 85.2% | 71.0% |
| 8iprA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.62 | 53.0 | 4.07e-01 | 92.6% | 88.4% |
| 7cfmR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 49.0 | 3.97e-01 | 90.4% | 99.2% |
| 4ib4A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 48.0 | 3.80e-01 | 88.1% | 90.9% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 44.0 | 4.14e-01 | 100.0% | 65.2% |
| 2qgzA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 33.0 | 3.10e-01 | 94.8% | 41.8% |
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.57 | 35.0 | 3.92e-01 | 84.4% | 79.4% |
| 1dofA01 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.55 | 45.0 | 3.74e-01 | 87.4% | 88.9% |
| 1qkrB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.55 | 45.0 | 4.12e-01 | 87.4% | 81.7% |
| 6rv2A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 45.0 | 3.64e-01 | 100.0% | 46.5% |
| 2i39B00 | 1.10.437.20 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus | 0.55 | 37.0 | 3.88e-01 | 89.6% | 75.6% |
| 4nqfA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.54 | 38.0 | 3.75e-01 | 72.6% | 89.7% |
| 2epgB00 | 3.90.1860.10 | Alpha Beta › Alpha-Beta Complex › tRNA-splicing ligase RtcB › tRNA-splicing ligase RtcB | 0.52 | 43.0 | 3.01e-01 | 87.4% | 84.2% |
| 7ae2A01 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.52 | 40.0 | 4.00e-01 | 85.2% | 79.6% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.52 | 46.0 | 4.09e-01 | 98.5% | 68.3% |
| 8amqA02 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.52 | 43.0 | 3.19e-01 | 91.1% | 70.2% |
| 4iggB06 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.51 | 41.0 | 3.59e-01 | 86.7% | 69.3% |
| 4dvyP01 | 1.10.357.130 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.51 | 46.0 | 4.08e-01 | 100.0% | 75.6% |
| 4w8kA02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.51 | 42.0 | 3.80e-01 | 92.6% | 91.9% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.50 | 38.0 | 3.83e-01 | 83.7% | 78.5% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3602825 | 633.12.1.0 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like | 0.77 | 48.0 | 4.96e-01 | 100.0% | 65.4% |
| 5002309 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.67 | 44.0 | 4.05e-01 | 100.0% | 51.4% |
| 3726914 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.66 | 42.0 | 4.13e-01 | 85.2% | 59.3% |
| 3187372 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.65 | 46.0 | 4.21e-01 | 72.6% | 75.6% |
| 4011838 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.65 | 53.0 | 4.25e-01 | 88.1% | 93.0% |
| 4647869 | 5001.1.1.87 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › EXS | 0.63 | 50.0 | 3.80e-01 | 83.7% | 46.3% |
| 4020563 | 601.16.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › GIT1_C | 0.62 | 37.0 | 3.83e-01 | 85.2% | 60.8% |
| 4011437 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.62 | 51.0 | 4.20e-01 | 88.1% | 91.4% |
| 4214881 | 5001.1.1.9 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R | 0.62 | 50.0 | 3.86e-01 | 87.4% | 89.4% |
| 3171851 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 42.0 | 3.97e-01 | 85.2% | 58.7% |
| 3700264 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.61 | 41.0 | 4.26e-01 | 84.4% | 71.5% |
| 4190986 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.60 | 48.0 | 3.67e-01 | 86.7% | 80.6% |
| 4019333 | 5001.1.1.8 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HlyIII | 0.60 | 47.0 | 4.00e-01 | 84.4% | 67.1% |
| 3545988 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.59 | 41.0 | 3.73e-01 | 70.4% | 69.4% |
| 3622827 | 5001.1.1.87 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › EXS | 0.59 | 47.0 | 3.63e-01 | 83.7% | 95.7% |
| 3227635 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.59 | 55.0 | 5.16e-01 | 98.5% | 99.4% |
| 3269062 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.59 | 47.0 | 3.63e-01 | 86.7% | 80.3% |
| 3239589 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.58 | 54.0 | 5.11e-01 | 100.0% | 85.8% |
| 3173473 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.58 | 34.0 | 4.16e-01 | 94.8% | 88.9% |
| 3789617 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.58 | 53.0 | 4.86e-01 | 97.8% | 93.5% |
| 3991594 | 601.42.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle in ROQ domain › Helical bundle in ROQ domain | 0.58 | 47.0 | 4.42e-01 | 88.1% | 88.2% |
| 3173369 | 5059.1.1.3 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT | 0.57 | 40.0 | 2.95e-01 | 70.4% | 80.3% |
| 3708470 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 44.0 | 3.57e-01 | 82.2% | 54.4% |
| 3700729 | 601.39.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Enhancer of filamentation 1 › Enhancer of filamentation 1 | 0.56 | 42.0 | 4.01e-01 | 87.4% | 67.7% |
| 5001086 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.55 | 42.0 | 3.75e-01 | 80.0% | 73.8% |
| 3828380 | 4177.1.1.11 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF632 | 0.55 | 49.0 | 3.97e-01 | 100.0% | 97.8% |
| 3598955 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.54 | 34.0 | 3.82e-01 | 100.0% | 81.0% |
| 3731086 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 43.0 | 3.53e-01 | 83.7% | 79.9% |
| 4069363 | 633.13.1.1 ↗ | alpha bundles › Bromodomain-like › DsbB-like › DsbB-like › DsbB | 0.54 | 50.0 | 4.73e-01 | 100.0% | 97.5% |
| 3684737 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 43.0 | 3.53e-01 | 83.7% | 78.7% |
| 3219872 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.53 | 38.0 | 3.82e-01 | 85.9% | 71.4% |
| 4994485 | 3745.1.1.1 ↗ | alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex | 0.53 | 47.0 | 3.68e-01 | 100.0% | 59.0% |
| 3212957 | 109.3.1.393 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › PF29588 | 0.53 | 37.0 | 3.42e-01 | 85.2% | 57.1% |
| 4413986 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 47.0 | 3.71e-01 | 100.0% | 71.5% |
| 4969650 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.51 | 39.0 | 3.10e-01 | 79.3% | 81.4% |
| 3688033 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.51 | 39.0 | 3.59e-01 | 93.3% | 61.1% |
| 4990614 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.51 | 39.0 | 3.14e-01 | 83.0% | 49.6% |
| 5028980 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.50 | 42.0 | 3.70e-01 | 91.1% | 93.5% |
D2
medium
residues 1-72
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF06070.16 best | Herpes_UL32 | 31.9 | 4.40e-08 | 98.6% | 6.5% |
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.72 | 60.0 | 5.18e-01 | 91.7% | 92.0% |
| 3lxrF00 | 1.10.4120.20 | Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › | 0.70 | 61.0 | 4.54e-01 | 97.2% | 86.7% |
| 1yozA00 | 1.10.3200.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like | 0.64 | 49.0 | 4.29e-01 | 84.7% | 72.6% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.62 | 51.0 | 4.05e-01 | 91.7% | 78.9% |
| 4kjmA02 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.62 | 36.0 | 4.08e-01 | 70.8% | 76.4% |
| 1m3sB00 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.62 | 51.0 | 3.88e-01 | 94.4% | 86.3% |
| 2lsgA00 | 1.20.58.1280 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DNA repair protein Rev1, C-terminal domain | 0.62 | 50.0 | 4.59e-01 | 90.3% | 67.0% |
| 2gsvA00 | 6.10.140.40 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 52.0 | 5.35e-01 | 93.1% | 100.0% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 50.0 | 4.35e-01 | 88.9% | 88.0% |
| 6tmfT00 | 1.10.60.20 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 | 0.60 | 45.0 | 4.80e-01 | 90.3% | 90.6% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.60 | 44.0 | 3.96e-01 | 80.6% | 76.6% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 47.0 | 4.73e-01 | 87.5% | 94.5% |
| 3ut4A00 | 1.25.40.750 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Domain of unknown function DUF5071 | 0.59 | 40.0 | 3.37e-01 | 93.1% | 39.8% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.59 | 41.0 | 3.86e-01 | 72.2% | 66.3% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 43.0 | 3.75e-01 | 80.6% | 87.3% |
| 2lefA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.58 | 40.0 | 3.74e-01 | 70.8% | 77.9% |
| 2co9A00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.58 | 39.0 | 3.48e-01 | 70.8% | 67.6% |
| 1dtoA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.57 | 46.0 | 4.03e-01 | 84.7% | 73.5% |
| 2jexA01 | 1.10.287.30 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › E2 (early) protein, N terminal domain, subdomain 1 | 0.57 | 44.0 | 4.04e-01 | 83.3% | 77.1% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.57 | 47.0 | 3.97e-01 | 90.3% | 80.7% |
| 2lt3A01 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.56 | 44.0 | 4.02e-01 | 88.9% | 90.0% |
| 4g1tA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 37.0 | 3.92e-01 | 79.2% | 80.3% |
| 3pe0A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 44.0 | 4.06e-01 | 91.7% | 96.0% |
| 5pg1A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.55 | 46.0 | 4.03e-01 | 98.6% | 80.9% |
| 2oyyA00 | 6.10.80.10 | Special › Helix non-globular › DNA polymerase; domain 1 › Hexameric tyrosine-coordinated heme protein (HTHP) | 0.54 | 39.0 | 3.99e-01 | 76.4% | 98.6% |
| 2i6jA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.54 | 46.0 | 3.68e-01 | 100.0% | 54.7% |
| 1ikpA02 | 3.90.1350.10 | Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain | 0.53 | 46.0 | 3.66e-01 | 100.0% | 63.9% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 41.0 | 3.55e-01 | 88.9% | 83.5% |
| 4pklA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 42.0 | 3.82e-01 | 100.0% | 82.7% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4926806 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.69 | 58.0 | 5.39e-01 | 91.7% | 95.6% |
| 5001327 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.65 | 45.0 | 4.12e-01 | 70.8% | 98.9% |
| 3243368 | 633.24.1.4 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › RIN1 | 0.65 | 52.0 | 4.66e-01 | 91.7% | 93.3% |
| 4180990 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.64 | 56.0 | 5.47e-01 | 100.0% | 88.7% |
| 3570202 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.61 | 47.0 | 4.27e-01 | 84.7% | 72.0% |
| 3389963 | 1134.1.1.0 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain | 0.59 | 47.0 | 4.74e-01 | 90.3% | 98.6% |
| 3353941 | 1134.1.1.7 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 | 0.59 | 46.0 | 4.78e-01 | 91.7% | 92.3% |
| 3251599 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.58 | 46.0 | 4.65e-01 | 93.1% | 94.7% |
| 3580914 | 604.12.1.2 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 | 0.58 | 51.0 | 4.88e-01 | 100.0% | 89.4% |
| 4397104 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.56 | 39.0 | 3.92e-01 | 73.6% | 74.7% |
| 3901917 | 1134.1.1.7 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › ALA1 | 0.55 | 44.0 | 4.53e-01 | 90.3% | 95.7% |
| 3649926 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.54 | 43.0 | 3.42e-01 | 86.1% | 58.7% |
| 3689265 | 109.1.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C | 0.54 | 46.0 | 3.31e-01 | 97.2% | 96.4% |
| 3584334 | 604.12.1.56 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ASTER | 0.54 | 45.0 | 4.16e-01 | 90.3% | 76.7% |
| 5044957 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.54 | 40.0 | 4.07e-01 | 77.8% | 81.4% |
| 3538104 | 7061.1.1.1 ↗ | few secondary structure elements › VWF C8-3 module › VWF C8-3 module › VWF C8-3 module › C8 | 0.52 | 36.0 | 3.60e-01 | 75.0% | 80.0% |
| 3610708 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.51 | 41.0 | 3.48e-01 | 84.7% | 78.3% |
D3
medium
residues 213-280
Domain cluster:
representative
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.77 | 57.0 | 4.41e-01 | 77.9% | 76.6% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.75 | 66.0 | 5.08e-01 | 98.5% | 58.2% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 54.0 | 3.97e-01 | 83.8% | 86.7% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 58.0 | 4.04e-01 | 92.6% | 77.6% |
| 3kztA00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.64 | 47.0 | 3.73e-01 | 76.5% | 89.4% |
| 1lq7A00 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.64 | 52.0 | 5.25e-01 | 92.6% | 100.0% |
| 2felA00 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.63 | 54.0 | 3.51e-01 | 100.0% | 31.2% |
| 3o10C00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.62 | 50.0 | 4.01e-01 | 88.2% | 78.7% |
| 3rauA00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.60 | 50.0 | 3.20e-01 | 92.6% | 25.7% |
| 3hx3A01 | 1.10.8.20 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › N-terminal domain of phosphatidylinositol transfer protein sec14p | 0.60 | 46.0 | 4.71e-01 | 83.8% | 97.0% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.58 | 44.0 | 4.17e-01 | 100.0% | 69.4% |
| 4kjmA02 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.58 | 43.0 | 4.70e-01 | 80.9% | 100.0% |
| 3rkoF01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.56 | 45.0 | 3.53e-01 | 92.6% | 48.8% |
| 3d5lA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.55 | 37.0 | 4.14e-01 | 70.6% | 90.4% |
| 3bbzA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.55 | 37.0 | 4.17e-01 | 82.4% | 100.0% |
| 4heoA00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.55 | 40.0 | 4.23e-01 | 92.6% | 98.2% |
| 2yysA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.53 | 41.0 | 2.73e-01 | 83.8% | 36.6% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3576527 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.82 | 57.0 | 4.29e-01 | 72.1% | 52.0% |
| 3422458 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.77 | 57.0 | 5.65e-01 | 77.9% | 82.9% |
| 3879800 | 601.3.1.8 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › IQUB | 0.77 | 66.0 | 5.23e-01 | 95.6% | 51.4% |
| 3719985 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.77 | 68.0 | 5.87e-01 | 98.5% | 79.0% |
| 4602773 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.75 | 67.0 | 5.30e-01 | 98.5% | 76.3% |
| 3289277 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.75 | 59.0 | 3.55e-01 | 97.1% | 12.3% |
| 3906133 | 633.21.1.4 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › Cg6151-P | 0.74 | 62.0 | 5.22e-01 | 92.6% | 78.3% |
| 3741935 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.73 | 50.0 | 3.58e-01 | 70.6% | 62.7% |
| 3865887 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.72 | 62.0 | 5.82e-01 | 98.5% | 97.6% |
| 3204035 | 1.1.17.4 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_S64 | 0.70 | 51.0 | 3.18e-01 | 76.5% | 53.2% |
| 3833190 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.68 | 58.0 | 4.62e-01 | 100.0% | 57.0% |
| 5054069 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 57.0 | 4.57e-01 | 95.6% | 75.0% |
| 3424617 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.66 | 54.0 | 4.36e-01 | 91.2% | 75.6% |
| 4031266 | 632.2.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › GA | 0.59 | 43.0 | 4.73e-01 | 80.9% | 100.0% |
| 3163896 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.59 | 52.0 | 3.69e-01 | 100.0% | 91.0% |
| 1503071 | 632.2.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › GA | 0.57 | 42.0 | 4.51e-01 | 92.6% | 100.0% |
| 1155488 | 632.2.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › GA | 0.56 | 45.0 | 4.66e-01 | 95.6% | 96.8% |
| 3428408 | 632.2.1.30 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › Auxin_canalis | 0.51 | 41.0 | 4.08e-01 | 95.6% | 88.0% |
| 3453972 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.51 | 45.0 | 3.56e-01 | 100.0% | 82.9% |
| 3474890 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.50 | 41.0 | 3.49e-01 | 94.1% | 95.0% |